ATE493491T1 - Verfahren und kit zur schnellen isolierung humaner foxp3-treg-zellen - Google Patents

Verfahren und kit zur schnellen isolierung humaner foxp3-treg-zellen

Info

Publication number: ATE493491T1
Authority: AT; Austria
Prior art keywords: treg cells; kit; foxp3; human foxp3; cells
Prior art date: 2007-10-12

Application number

AT07020026T

Other languages

English (en)

Inventor

Olaf Roetzschke

Kirsten Falk

Markus Kleinewietfeld

Original Assignee

Max Delbrueck Centrum

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2007-10-12

Filing date

2007-10-12

Publication date

2011-01-15

2007-10-12 Application filed by Max Delbrueck Centrum filed Critical Max Delbrueck Centrum

2011-01-15 Application granted granted Critical

2011-01-15 Publication of ATE493491T1 publication Critical patent/ATE493491T1/de

Links

238000002955 isolation Methods 0.000 title abstract 2
238000000034 method Methods 0.000 title abstract 2
210000003289 regulatory T cell Anatomy 0.000 abstract 4
210000003819 peripheral blood mononuclear cell Anatomy 0.000 abstract 2
101000861452 Homo sapiens Forkhead box protein P3 Proteins 0.000 abstract 1
101001057504 Homo sapiens Interferon-stimulated gene 20 kDa protein Proteins 0.000 abstract 1
101001055144 Homo sapiens Interleukin-2 receptor subunit alpha Proteins 0.000 abstract 1
102100027268 Interferon-stimulated gene 20 kDa protein Human genes 0.000 abstract 1
102000053917 human FOXP3 Human genes 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/10—Cellular immunotherapy characterised by the cell type used
- A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/20—Cellular immunotherapy characterised by the effect or the function of the cells
- A61K40/22—Immunosuppressive or immunotolerising
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
- A61K40/41—Vertebrate antigens
- A61K40/418—Antigens related to induction of tolerance to non-self
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0081—Purging biological preparations of unwanted cells
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0081—Purging biological preparations of unwanted cells
- C12N5/0087—Purging against subsets of blood cells, e.g. purging alloreactive T cells
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0636—T lymphocytes

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Biomedical Technology (AREA)
Bioinformatics & Cheminformatics (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Zoology (AREA)
Wood Science & Technology (AREA)
Genetics & Genomics (AREA)
Biotechnology (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Epidemiology (AREA)
Cell Biology (AREA)
Microbiology (AREA)
Immunology (AREA)
Biochemistry (AREA)
General Engineering & Computer Science (AREA)
Hematology (AREA)
Molecular Biology (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)

AT07020026T 2007-10-12 2007-10-12 Verfahren und kit zur schnellen isolierung humaner foxp3-treg-zellen ATE493491T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP07020026A EP2048225B1 (de)	2007-10-12	2007-10-12	Verfahren und Kit zur schnellen Isolierung humaner Foxp3-Treg-Zellen

Publications (1)

Publication Number	Publication Date
ATE493491T1 true ATE493491T1 (de)	2011-01-15

Family

ID=39047498

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT07020026T ATE493491T1 (de)	2007-10-12	2007-10-12	Verfahren und kit zur schnellen isolierung humaner foxp3-treg-zellen

Country Status (4)

Country	Link
EP (1)	EP2048225B1 (de)
AT (1)	ATE493491T1 (de)
DE (1)	DE602007011626D1 (de)
ES (1)	ES2355587T3 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN110187107A (zh) *	2019-04-26	2019-08-30	温州医科大学	一种基于肿瘤组织浸润免疫细胞特征建立的结直肠癌预后评估装置及方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6017719A (en) *	1994-06-14	2000-01-25	Nexell Therapeutics, Inc.	Positive and positive/negative cell selection mediated by peptide release
ATE476496T1 (de) *	1996-03-04	2010-08-15	Calyx Bio Ventures Inc	Modifizierte schnellvermehrungsmethode ('modified-rem') zur in vitro vermehrung von t-lymphozyten

2007
- 2007-10-12 AT AT07020026T patent/ATE493491T1/de not_active IP Right Cessation
- 2007-10-12 DE DE602007011626T patent/DE602007011626D1/de active Active
- 2007-10-12 ES ES07020026T patent/ES2355587T3/es active Active
- 2007-10-12 EP EP07020026A patent/EP2048225B1/de active Active

Also Published As

Publication number	Publication date
EP2048225B1 (de)	2010-12-29
ES2355587T3 (es)	2011-03-29
DE602007011626D1 (de)	2011-02-10
EP2048225A1 (de)	2009-04-15

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Legal Events

Date	Code	Title	Description
2011-06-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties