|
US4327080A
(en)
|
1981-07-13 |
1982-04-27 |
E. R. Squibb & Sons, Inc. |
Novel Bendroflumethiazide formulations and method
|
|
US5002776A
(en)
*
|
1983-12-22 |
1991-03-26 |
Elan Corporation, Plc |
Controlled absorption diltiazem formulations
|
|
GB8608335D0
(en)
|
1986-04-04 |
1986-05-08 |
Pfizer Ltd |
Pharmaceutically acceptable salts
|
|
US4808413A
(en)
*
|
1987-04-28 |
1989-02-28 |
E. R. Squibb & Sons, Inc. |
Pharmaceutical compositions in the form of beadlets and method
|
|
US5049394A
(en)
|
1987-09-11 |
1991-09-17 |
E. R. Squibb & Sons, Inc. |
Pharmaceutical composition containing high drug load and method for preparing same
|
|
US5744166A
(en)
|
1989-02-25 |
1998-04-28 |
Danbiosyst Uk Limited |
Drug delivery compositions
|
|
US5212165A
(en)
|
1989-10-23 |
1993-05-18 |
E. R. Squibb & Sons, Inc. |
Method for rehabilitating the vasorelaxant action of the coronary arteries impaired through atherosclerosis or hypercholesterolemia employing an ace inhibitor
|
|
US5707644A
(en)
|
1989-11-04 |
1998-01-13 |
Danbiosyst Uk Limited |
Small particle compositions for intranasal drug delivery
|
|
FR2681067B1
(fr)
|
1991-09-10 |
1993-12-17 |
Elf Sanofi |
Derives heterocycliques n-substitues, leur preparation, les compositions pharmaceutiques en contenant.
|
|
FR2665702B1
(fr)
|
1990-08-08 |
1994-02-25 |
Sanofi |
Derives heterocycliques n-substitues, leur preparation, les compositions pharmaceutiques en contenant.
|
|
TW201738B
(de)
|
1990-03-20 |
1993-03-11 |
Sanofi Co |
|
|
US5270317A
(en)
|
1990-03-20 |
1993-12-14 |
Elf Sanofi |
N-substituted heterocyclic derivatives, their preparation and the pharmaceutical compositions in which they are present
|
|
FR2659967B1
(fr)
|
1990-03-20 |
1992-07-24 |
Sanofi Sa |
Derives d'imidazolinone n-substitues, leur preparation, les compositions pharmaceutiques en contenant.
|
|
US5298497A
(en)
*
|
1990-05-15 |
1994-03-29 |
E. R. Squibb & Sons, Inc. |
Method for preventing onset of hypertension employing a cholesterol lowering drug
|
|
US5140012A
(en)
|
1990-05-31 |
1992-08-18 |
E. R. Squibb & Sons, Inc. |
Method for preventing onset of restenosis after angioplasty employing pravastatin
|
|
US5622985A
(en)
|
1990-06-11 |
1997-04-22 |
Bristol-Myers Squibb Company |
Method for preventing a second heart attack employing an HMG CoA reductase inhibitor
|
|
US5137902A
(en)
|
1990-07-13 |
1992-08-11 |
E. I. Du Pont De Nemours And Company |
4-alkylimidazole derivatives and anti-hypertensive use thereof
|
|
US5089626A
(en)
*
|
1990-08-23 |
1992-02-18 |
Merck & Co., Inc. |
Process for preparing an angiotensin II antagonist
|
|
US5098889A
(en)
*
|
1990-09-17 |
1992-03-24 |
E. R. Squibb & Sons, Inc. |
Method for preventing or inhibiting loss of cognitive function employing a combination of an ace inhibitor and a drug that acts at serotonin receptors
|
|
US5032578A
(en)
|
1990-09-17 |
1991-07-16 |
E. R. Squibb & Sons, Inc. |
Method for preventing or treating depression employing a combination of an ace inhibitor and a drug that acts at serotonin receptors
|
|
US6025380A
(en)
*
|
1990-12-14 |
2000-02-15 |
Smithkline Beecham Plc |
Medicament
|
|
US6028091A
(en)
*
|
1990-12-14 |
2000-02-22 |
Smithkline Beecham Plc |
Medicament
|
|
US6034114A
(en)
*
|
1990-12-14 |
2000-03-07 |
Smithkline Beecham Plc |
Medicament
|
|
US20010016594A1
(en)
|
1990-12-14 |
2001-08-23 |
Smithkline Beecham P.L.C. |
Medicament
|
|
KR100222252B1
(ko)
|
1990-12-14 |
1999-10-01 |
스튜어트 알. 수터 |
안지오텐신 ii 수용체 차단 조성물
|
|
US5472967A
(en)
|
1991-02-20 |
1995-12-05 |
Synthelabo |
4-pyrimidinone derivatives their preparation and their application in therapy
|
|
FR2673427B1
(fr)
|
1991-03-01 |
1993-06-18 |
Sanofi Elf |
Derives heterocycliques diazotes n-substitues par un groupement biphenylmethyle, leur preparation, les compositions pharmaceutiques en contenant.
|
|
FR2677984B1
(fr)
|
1991-06-21 |
1994-02-25 |
Elf Sanofi |
Derives d'imidazoline n-substitues, leur preparation, les compositions pharmaceutiques en contenant.
|
|
DE59202126D1
(de)
*
|
1991-07-01 |
1995-06-14 |
Gergely Gerhard |
Verfahren zur Herstellung einer pharmazeutischen Zubereitung mit wenigstens zwei verschiedenen Wirkstoffen und Verwendung einer solchen Zubereitung.
|
|
AU2494792A
(en)
|
1991-08-19 |
1993-03-16 |
E.I. Du Pont De Nemours And Company |
Angiotensin ii receptor blocking imidazolinone derivatives
|
|
WO1993004045A1
(en)
|
1991-08-19 |
1993-03-04 |
E.I. Du Pont De Nemours And Company |
Angiotensin ii receptor blocking imidazolinone derivatives
|
|
ATE216577T1
(de)
*
|
1992-01-29 |
2002-05-15 |
Takeda Chemical Industries Ltd |
Schnellösliche tablette und ihre herstellung
|
|
FR2688781B1
(fr)
|
1992-03-23 |
1994-07-01 |
Sanofi Elf |
Imidazolines n-substituees par un groupement biphenylmethyle, leur preparation, les compositions pharmaceutiques en contenant.
|
|
GB9208116D0
(en)
|
1992-04-13 |
1992-05-27 |
Ici Plc |
Therapeutic agents
|
|
US6673824B1
(en)
*
|
1992-05-06 |
2004-01-06 |
Bristol-Myers Squibb Co. |
Phenyl sulfonamide endothelin antagonists
|
|
EP0577023A3
(en)
|
1992-07-01 |
1996-12-18 |
Hoechst Ag |
Angiotensin-ii receptor-antagonists for the treatment of arrhythmices
|
|
US5472711A
(en)
|
1992-07-30 |
1995-12-05 |
Edward Mendell Co., Inc. |
Agglomerated hydrophilic complexes with multi-phasic release characteristics
|
|
AU5449194A
(en)
|
1992-10-26 |
1994-05-24 |
Merck & Co., Inc. |
Combinations of angiotensin-ii receptor antagonists and diuretics
|
|
US5457112A
(en)
|
1992-12-14 |
1995-10-10 |
Synthelabo |
3-(6-quinolylmethyl)-4H-imidazol-4-one derivatives, their preparation and their application in therapy
|
|
NZ262679A
(en)
*
|
1993-02-22 |
1997-08-22 |
Vivorx Pharmaceuticals Inc |
Compositions for in vivo delivery of pharmaceutical agents where the agents are contained in a polymeric shell
|
|
US5914132A
(en)
|
1993-02-26 |
1999-06-22 |
The Procter & Gamble Company |
Pharmaceutical dosage form with multiple enteric polymer coatings for colonic delivery
|
|
EP0635263A3
(de)
|
1993-06-28 |
1995-09-27 |
American Cyanamid Co |
Angiotensin (AII)-antagonisten als Inhibitoren des Wachstums von Fettgewebe.
|
|
FR2708606B1
(fr)
|
1993-07-30 |
1995-10-27 |
Sanofi Sa |
Dérivés du N-phénylalkylindol-2-one, leur préparation, les compositions pharmaceutiques en contenant.
|
|
FR2708608B1
(fr)
|
1993-07-30 |
1995-10-27 |
Sanofi Sa |
Dérivés de N-sulfonylbenzimidazolone, leur préparation, les compositions pharmaceutiques en contenant.
|
|
US5514670A
(en)
|
1993-08-13 |
1996-05-07 |
Pharmos Corporation |
Submicron emulsions for delivery of peptides
|
|
US5824696A
(en)
|
1993-09-01 |
1998-10-20 |
Smithkline Beecham Corporation |
Medicaments
|
|
US6174917B1
(en)
*
|
1993-09-08 |
2001-01-16 |
Pharmacy And Therapeutic Advisory Consultancy Ltd. |
Method of treating liver disease and like indications with vasodilating agents
|
|
US5464854A
(en)
|
1993-11-11 |
1995-11-07 |
Depadova; Anathony S. |
Method of modifying ovarian hormone-regulated AT1 receptor activity as treatment of incapacitating symptom(s) of P.M.S.
|
|
JPH09510182A
(ja)
*
|
1993-11-17 |
1997-10-14 |
エルディーエス・テクノロジーズ・インコーポレーテッド |
カプセル封入されたドラッグデリバリー用透明液
|
|
US5536505A
(en)
|
1993-12-15 |
1996-07-16 |
Eastman Chemical Company |
Controlled release matrix system using cellulose acetate/poly-2-ethyl-2-oxazoline blends
|
|
US5523095A
(en)
|
1993-12-15 |
1996-06-04 |
Eastman Chemical Company |
Controlled release matrix system using cellulose acetate/polyvinylpyrrolidone blends
|
|
ATE300287T1
(de)
*
|
1994-02-08 |
2005-08-15 |
Novartis Pharma Gmbh |
Behandlung von normaldruckglaukom mit valsartan
|
|
JP3414539B2
(ja)
*
|
1994-05-11 |
2003-06-09 |
有限会社ドット |
経鼻吸収用組成物
|
|
US6645463B1
(en)
|
1994-05-16 |
2003-11-11 |
The Board Of Regents Of The University Of Michigan |
Blood-pool selective carrier for lipophilic imaging agents
|
|
US5464633A
(en)
|
1994-05-24 |
1995-11-07 |
Jagotec Ag |
Pharmaceutical tablets releasing the active substance after a definite period of time
|
|
US5541209A
(en)
|
1994-08-22 |
1996-07-30 |
Bristol-Myers Squibb Company |
Method of treating or preventing cardiac arrhythmia employing an N-substituted heterocyclic derivative
|
|
US5612359A
(en)
*
|
1994-08-26 |
1997-03-18 |
Bristol-Myers Squibb Company |
Substituted biphenyl isoxazole sulfonamides
|
|
FR2725987B1
(fr)
|
1994-10-19 |
1997-01-10 |
Sanofi Sa |
Procede pour la preparation d'un derive de tetrazole sous deux formes cristallines et nouvelle forme cristalline de ce derive
|
|
US6485726B1
(en)
|
1995-01-17 |
2002-11-26 |
The Brigham And Women's Hospital, Inc. |
Receptor specific transepithelial transport of therapeutics
|
|
US5780473A
(en)
|
1995-02-06 |
1998-07-14 |
Bristol-Myers Squibb Company |
Substituted biphenyl sulfonamide endothelin antagonists
|
|
CA2168066A1
(en)
|
1995-02-08 |
1996-08-09 |
James R. Powell |
Treatment of hypertension and congestive heart failure
|
|
FR2732223B1
(fr)
*
|
1995-03-30 |
1997-06-13 |
Sanofi Sa |
Composition pharmaceutique pour administration transdermique
|
|
US5731339A
(en)
*
|
1995-04-28 |
1998-03-24 |
Zonagen, Inc. |
Methods and formulations for modulating the human sexual response
|
|
US20020094346A1
(en)
|
1995-05-17 |
2002-07-18 |
M. D. Henry C. Lin |
Method and compositions for improving digestion and absorption in the small intestine
|
|
US5686106A
(en)
|
1995-05-17 |
1997-11-11 |
The Procter & Gamble Company |
Pharmaceutical dosage form for colonic delivery
|
|
SE9501881D0
(sv)
|
1995-05-19 |
1995-05-19 |
Astra Ab |
New pharmacological use of AII-receptor antagonists
|
|
TW442301B
(en)
*
|
1995-06-07 |
2001-06-23 |
Sanofi Synthelabo |
Pharmaceutical compositions containing irbesartan
|
|
US5994348A
(en)
*
|
1995-06-07 |
1999-11-30 |
Sanofi |
Pharmaceutical compositions containing irbesartan
|
|
US5645839A
(en)
|
1995-06-07 |
1997-07-08 |
Trustees Of Boston University |
Combined use of angiotensin inhibitors and nitric oxide stimulators to treat fibrosis
|
|
AU725689B2
(en)
|
1995-06-07 |
2000-10-19 |
G.D. Searle & Co. |
Epoxy-steroidal aldosterone antagonist and angiotensin II antagonist combination therapy for treatment of congestive heart failure
|
|
FR2735365B1
(fr)
|
1995-06-14 |
1997-09-05 |
Sanofi Sa |
Utilisation d'un antagoniste de l'angiotensine ii et d'un derive du benzofurane pour la preparation d'un medicament utile dans le traitement des affections cardiovasculaires
|
|
SE9502219D0
(sv)
|
1995-06-19 |
1995-06-19 |
Astra Ab |
Novel medical use
|
|
US6057139A
(en)
*
|
1995-06-29 |
2000-05-02 |
Mcneil-Ppc, Inc. |
Preblend of microcrystalline cellulose and lactase for making tablets
|
|
US5846990A
(en)
|
1995-07-24 |
1998-12-08 |
Bristol-Myers Squibb Co. |
Substituted biphenyl isoxazole sulfonamides
|
|
FR2740136B1
(fr)
|
1995-10-24 |
1998-01-09 |
Sanofi Sa |
Derives d'indolin-2-one, procede pour leur preparation et les compositions pharmaceutiques les contenant
|
|
FR2740686B1
(fr)
|
1995-11-03 |
1998-01-16 |
Sanofi Sa |
Formulation pharmaceutique lyophilisee stable
|
|
DK0883401T3
(da)
*
|
1996-02-29 |
2003-05-05 |
Novartis Ag |
AT1-receptorantagonist til stimulering af apoptose
|
|
FR2746013B1
(fr)
|
1996-03-18 |
1998-05-29 |
Sanofi Sa |
Utilisation de composes antiarythmiques dans la prevention de la mortalite post infarctus
|
|
US5939446A
(en)
|
1996-04-09 |
1999-08-17 |
Bristol-Myers Squibb Co. |
Heteroaryl substituted phenyl isoxazole sulfonamide endothelin antagonists
|
|
DE69731840T2
(de)
*
|
1996-07-15 |
2005-08-04 |
Sankyo Co., Ltd. |
Pharmazeutische Zusammensetzungen enthaltend CS-866 und Insulinresistenz verbessernde Mittel und deren Verwendung zur Behandlung von Arteriosklerose und Xanthom
|
|
US5891469A
(en)
|
1997-04-02 |
1999-04-06 |
Pharmos Corporation |
Solid Coprecipitates for enhanced bioavailability of lipophilic substances
|
|
HRP970493A2
(en)
*
|
1996-09-23 |
1998-08-31 |
Wienman E. Phlips |
Oral delayed immediate release medical formulation and method for preparing the same
|
|
ATE314097T1
(de)
|
1996-10-28 |
2006-01-15 |
Amersham Health As |
Kontrastmittel
|
|
US6008221A
(en)
|
1996-11-06 |
1999-12-28 |
Bristol-Myers Squibb Company |
Method for treating Alzheimer's disease with folic acid
|
|
US6019988A
(en)
*
|
1996-11-18 |
2000-02-01 |
Bristol-Myers Squibb Company |
Methods and compositions for enhancing skin permeation of drugs using permeation enhancers, when drugs and/or permeation enhancers are unstable in combination during long-term storage
|
|
FR2757157B1
(fr)
|
1996-12-13 |
1999-12-31 |
Sanofi Sa |
Derives d'indolin-2-one, procede pour leur preparation et compositions pharmaceutiques les contenant
|
|
US6201002B1
(en)
*
|
1997-01-10 |
2001-03-13 |
Merck & Co., Inc. |
Method for reducing mortality with an angiotensin II antagonist
|
|
EP0855392A3
(de)
*
|
1997-01-22 |
2000-01-05 |
Hoechst Aktiengesellschaft |
Fünfgliedrige Heterocyclen mit Biphenylsulfonylsubstitution, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
|
|
US5788987A
(en)
|
1997-01-29 |
1998-08-04 |
Poli Industria Chimica Spa |
Methods for treating early morning pathologies
|
|
TW536540B
(en)
*
|
1997-01-30 |
2003-06-11 |
Bristol Myers Squibb Co |
Endothelin antagonists: N-[[2'-[[(4,5-dimethyl-3-isoxazolyl)amino]sulfonyl]-4-(2-oxazolyl)[1,1'-biphenyl]-2-yl]methyl]-N,3,3-trimethylbutanamide and N-(4,5-dimethyl-3-isoxazolyl)-2'-[(3,3-dimethyl-2-oxo-1-pyrrolidinyl)methyl]-4'-(2-oxazolyl)[1,1'-biphe
|
|
WO1998033781A1
(en)
|
1997-01-30 |
1998-08-06 |
Bristol-Myers Squibb Company |
Method for preventing or treating low renin hypertension by administering an endothelin antagonist
|
|
US5846985A
(en)
|
1997-03-05 |
1998-12-08 |
Bristol-Myers Squibb Co. |
Substituted biphenyl isoxazole sulfonamides
|
|
TW580397B
(en)
|
1997-05-27 |
2004-03-21 |
Takeda Chemical Industries Ltd |
Solid preparation
|
|
DE19724696A1
(de)
|
1997-06-12 |
1998-12-24 |
Hexal Ag |
Pharmazeutische Zubereitung mit drei Pelletarten
|
|
CA2295177C
(en)
*
|
1997-06-13 |
2007-01-09 |
Medinova Medical Consulting Gmbh |
Drug targeting system, method of its preparation and its use
|
|
IT1292437B1
(it)
|
1997-06-30 |
1999-02-08 |
Zambon Spa |
Processo di orto-metallazione utile per la sintesi di 1 - tetrazol- 5-il) benzeni 2-sostituiti
|
|
HU218679B
(hu)
|
1997-07-25 |
2000-10-28 |
Sanofi-Synthelabo |
Eljárás imidazolonok előállítására és intermedierjeik
|
|
US20010044584A1
(en)
|
1997-08-28 |
2001-11-22 |
Kensey Kenneth R. |
In vivo delivery methods and compositions
|
|
GT199800126A
(es)
|
1997-08-29 |
2000-01-29 |
|
Terapia de combinacion.
|
|
NL1006903C2
(nl)
*
|
1997-09-01 |
1999-03-04 |
Johannes Gerardus Van Gemert |
Werkwijze voor het verdichten van vormzand.
|
|
PT942780E
(pt)
|
1997-09-09 |
2003-11-28 |
Lyotropic Therapeutics Inc |
Particulas revestidas processos de obtencao e uso
|
|
US6248358B1
(en)
|
1998-08-25 |
2001-06-19 |
Columbia Laboratories, Inc. |
Bioadhesive progressive hydration tablets and methods of making and using the same
|
|
US20030077229A1
(en)
|
1997-10-01 |
2003-04-24 |
Dugger Harry A. |
Buccal, polar and non-polar spray or capsule containing cardiovascular or renal drugs
|
|
KR100523112B1
(ko)
|
1997-10-17 |
2005-10-19 |
유로진 리미티드 |
레닌-안지오텐신계 억제제의 사용
|
|
DE19750529A1
(de)
*
|
1997-11-14 |
1999-05-20 |
Basf Ag |
Neue heterocyclisch substituierte alpha-Hydroxycarbonsäurederivate, ihre Herstellung und Verwendung als Endothelinrezeptorantagonisten
|
|
JPH11137208A
(ja)
*
|
1997-11-14 |
1999-05-25 |
Nikken Chem Co Ltd |
口腔内速溶性固形物及びその製造方法
|
|
CA2315088A1
(en)
*
|
1997-12-19 |
1999-07-01 |
Smithkline Beecham Corporation |
Process for manufacturing bite-dispersion tablets
|
|
US6162922A
(en)
|
1998-01-30 |
2000-12-19 |
Bristol-Myers Squibb Co. |
Method for preparing N-substituted heterocyclic derivatives using a phase-transfer catalyst
|
|
HRP980532B1
(en)
*
|
1998-10-02 |
2005-06-30 |
Pliva |
Novel crystalline torasemide modification
|
|
CA2318778A1
(en)
|
1998-02-25 |
1999-09-02 |
Merck & Co., Inc. |
Method for decreasing qt dispersion or inhibiting the progression of qt dispersion with an angiotensin ii receptor antagonist
|
|
AU2745199A
(en)
|
1998-03-04 |
1999-09-20 |
Takeda Chemical Industries Ltd. |
Sustained-release preparation for aii antagonist, production and use thereof
|
|
FR2775598A1
(fr)
|
1998-03-06 |
1999-09-10 |
Sanofi Sa |
Compositions pharmaceutiques contenant en association un antagoniste selectif des recepteurs v1a de l'arginine-vasopressine et un antagoniste selectif des recepteur v2 de l'arginine-vasopressine
|
|
US6284363B1
(en)
|
1998-03-23 |
2001-09-04 |
Fuji Polymer Industries Co., Ltd. |
Electromagnetic wave absorbing thermoconductive silicone gel molded sheet and method for producing the same
|
|
US20040062802A1
(en)
|
1998-04-02 |
2004-04-01 |
Hermelin Victor M. |
Maximizing effectiveness of substances used to improve health and well being
|
|
FR2778103A1
(fr)
|
1998-04-29 |
1999-11-05 |
Sanofi Sa |
Compositions pharmaceutiques contenant en association un antagoniste v1a de l'arginine-vasopressine et un antagoniste des recepteurs at1 de l'angiotensine ii
|
|
HUP0103714A3
(en)
|
1998-05-11 |
2003-05-28 |
Takeda Pharmaceutical |
Oxyiminoalkanoic acid derivatives with hypoglycemic and hypolipidemic activity, medicaments containing them and their use
|
|
AU750122C
(en)
|
1998-06-17 |
2003-02-27 |
Bristol-Myers Squibb Company |
Preventing cerebral infarction through administration of ADP-receptor antiplatelet and antihypertensive drugs in combination
|
|
IT1301759B1
(it)
|
1998-06-19 |
2000-07-07 |
Nicox Sa |
Sali nitrati di farmaci antiipertensivi
|
|
FR2780403B3
(fr)
*
|
1998-06-24 |
2000-07-21 |
Sanofi Sa |
Nouvelle forme de l'irbesartan, procedes pour obtenir ladite forme et compositions pharmaceutiques en contenant
|
|
US6638937B2
(en)
|
1998-07-06 |
2003-10-28 |
Bristol-Myers Squibb Co. |
Biphenyl sulfonamides as dual angiotensin endothelin receptor antagonists
|
|
FR2780890B3
(fr)
|
1998-07-10 |
2000-09-01 |
Sanofi Sa |
Utilisation d'une composition pharmaceutique contenant, en association, un antagoniste des recepteurs at1 de l'angiotensine ii et l'indomethacine pour le traitement des glomerulonephrites chroniques
|
|
TW585786B
(en)
|
1998-07-28 |
2004-05-01 |
Takeda Chemical Industries Ltd |
Lansoprazole-containing rapidly disintegrable solid pharmaceutical composition
|
|
CA2340206A1
(en)
*
|
1998-08-26 |
2000-03-09 |
Queen's University At Kingston |
Use of anti-pressor agents for vascular remodeling in genital dysfunction
|
|
US6489307B1
(en)
|
1998-09-14 |
2002-12-03 |
University Of Florida |
Antisense compositions targeted to β1-adrenoceptor-specific mRNA and methods of use
|
|
FR2783422A1
(fr)
|
1998-09-21 |
2000-03-24 |
Sanofi Sa |
Composition pharmaceutique contenant un antagoniste des recepteurs at1 de l'angiotensine ii et un antiagregant plaquettaire
|
|
US6531152B1
(en)
*
|
1998-09-30 |
2003-03-11 |
Dexcel Pharma Technologies Ltd. |
Immediate release gastrointestinal drug delivery system
|
|
US7815937B2
(en)
|
1998-10-27 |
2010-10-19 |
Biovail Laboratories International Srl |
Quick dissolve compositions and tablets based thereon
|
|
US6596747B2
(en)
|
1998-10-29 |
2003-07-22 |
Bristol-Myers Squibb Company |
Compounds derived from an amine nucleus and pharmaceutical compositions comprising same
|
|
US20040141925A1
(en)
|
1998-11-12 |
2004-07-22 |
Elan Pharma International Ltd. |
Novel triamcinolone compositions
|
|
US6478771B1
(en)
*
|
1998-11-13 |
2002-11-12 |
Elan Pharma International Limited |
Drug delivery systems and methods
|
|
TNSN99224A1
(fr)
|
1998-12-01 |
2005-11-10 |
Inst For Pharm Discovery Inc |
Methodes de reduction des niveaux de glucose et triglyceride en serum et pour suppression de l'antigenese utilisant les acides la indolealkanoique
|
|
FR2787330A1
(fr)
|
1998-12-18 |
2000-06-23 |
Sanofi Sa |
Composition pharmaceutique contenant, en association, un antagoniste des recepteurs at1 de l'angiotensine ii et un immunosuppresseur pour la prevention ou le traitement des complications vasculaires du rejet de greffe
|
|
KR100349597B1
(ko)
|
1999-01-12 |
2002-08-22 |
삼성전자 주식회사 |
광도파로 소자 및 그 제조방법
|
|
US6248363B1
(en)
|
1999-11-23 |
2001-06-19 |
Lipocine, Inc. |
Solid carriers for improved delivery of active ingredients in pharmaceutical compositions
|
|
US20030104048A1
(en)
|
1999-02-26 |
2003-06-05 |
Lipocine, Inc. |
Pharmaceutical dosage forms for highly hydrophilic materials
|
|
US6294192B1
(en)
*
|
1999-02-26 |
2001-09-25 |
Lipocine, Inc. |
Triglyceride-free compositions and methods for improved delivery of hydrophobic therapeutic agents
|
|
US7374779B2
(en)
|
1999-02-26 |
2008-05-20 |
Lipocine, Inc. |
Pharmaceutical formulations and systems for improved absorption and multistage release of active agents
|
|
CA2366602A1
(en)
*
|
1999-03-08 |
2000-09-14 |
Medicure Inc. |
Pyridoxal analogues for vitamin b-6 disorders
|
|
JP3695978B2
(ja)
|
1999-03-16 |
2005-09-14 |
三洋電機株式会社 |
渦巻状電極体を備えたアルカリ蓄電池
|
|
US6548529B1
(en)
|
1999-04-05 |
2003-04-15 |
Bristol-Myers Squibb Company |
Heterocyclic containing biphenyl aP2 inhibitors and method
|
|
US6383471B1
(en)
|
1999-04-06 |
2002-05-07 |
Lipocine, Inc. |
Compositions and methods for improved delivery of ionizable hydrophobic therapeutic agents
|
|
US6632451B2
(en)
|
1999-06-04 |
2003-10-14 |
Dexcel Pharma Technologies Ltd. |
Delayed total release two pulse gastrointestinal drug delivery system
|
|
US6387894B1
(en)
|
1999-06-11 |
2002-05-14 |
Pfizer Inc. |
Use of CRF antagonists and renin-angiotensin system inhibitors
|
|
CA2385798A1
(en)
|
1999-06-25 |
2001-01-04 |
Michael C. Van Zandt |
Substituted phenoxyacetic acids
|
|
US6309663B1
(en)
|
1999-08-17 |
2001-10-30 |
Lipocine Inc. |
Triglyceride-free compositions and methods for enhanced absorption of hydrophilic therapeutic agents
|
|
US20030235595A1
(en)
|
1999-06-30 |
2003-12-25 |
Feng-Jing Chen |
Oil-containing, orally administrable pharmaceutical composition for improved delivery of a therapeutic agent
|
|
SE9902597D0
(sv)
|
1999-07-06 |
1999-07-06 |
Astra Ab |
New use
|
|
US6677356B1
(en)
*
|
1999-08-24 |
2004-01-13 |
Medicure International Inc. |
Treatment of cardiovascular and related pathologies
|
|
US6432989B1
(en)
|
1999-08-27 |
2002-08-13 |
Pfizer Inc |
Use of CRF antagonists to treat circadian rhythm disorders
|
|
US20030225124A1
(en)
|
1999-08-31 |
2003-12-04 |
Spiridon Spireas |
Stable formulations of ACE inhibitors, and methods for preparation thereof
|
|
US6555551B1
(en)
|
1999-08-31 |
2003-04-29 |
Mutual Pharmaceutical Co., Inc. |
Stable formulations of ACE inhibitors, and methods for preparation thereof
|
|
WO2001017528A1
(en)
*
|
1999-09-08 |
2001-03-15 |
Nitromed, Inc. |
Methods of treating and preventing congestive heart failure with hydralazine compounds and isosorbide dinitrate or isosorbide mononitrate
|
|
US6414002B1
(en)
|
1999-09-22 |
2002-07-02 |
Bristol-Myers Squibb Company |
Substituted acid derivatives useful as antidiabetic and antiobesity agents and method
|
|
PH12000002657B1
(en)
|
1999-10-12 |
2006-02-21 |
Bristol Myers Squibb Co |
C-aryl glucoside SGLT2 inhibitors
|
|
US6515117B2
(en)
*
|
1999-10-12 |
2003-02-04 |
Bristol-Myers Squibb Company |
C-aryl glucoside SGLT2 inhibitors and method
|
|
US6720001B2
(en)
|
1999-10-18 |
2004-04-13 |
Lipocine, Inc. |
Emulsion compositions for polyfunctional active ingredients
|
|
US6323226B1
(en)
|
1999-10-19 |
2001-11-27 |
Texas Heart Institute |
Treatment of heart disease with cox-2 inhibitors
|
|
EP1093814A1
(de)
|
1999-10-22 |
2001-04-25 |
Boehringer Ingelheim Pharma KG |
Verwendung von Dipyridamole oder Mopidamol zur Herstellung eines Medikaments für die Behandlung und Vorbeugung von fibrinabhängigen Mikrozirkulationstörungen
|
|
US6264981B1
(en)
|
1999-10-27 |
2001-07-24 |
Anesta Corporation |
Oral transmucosal drug dosage using solid solution
|
|
US7537785B2
(en)
|
1999-10-29 |
2009-05-26 |
Nitromed, Inc. |
Composition for treating vascular diseases characterized by nitric oxide insufficiency
|
|
US6635273B1
(en)
|
1999-10-29 |
2003-10-21 |
Trustees Of Boston University |
Methods of treating vascular diseases characterized by nitric oxide insufficiency
|
|
US7235237B2
(en)
|
1999-10-29 |
2007-06-26 |
Nitromed, Inc. |
Methods of treating vascular diseases characterized by nitric oxide insufficiency
|
|
US20030113330A1
(en)
|
1999-11-08 |
2003-06-19 |
Uhal Bruce D. |
Methods for treating pulmonary fibrosis
|
|
US20030180352A1
(en)
|
1999-11-23 |
2003-09-25 |
Patel Mahesh V. |
Solid carriers for improved delivery of active ingredients in pharmaceutical compositions
|
|
IL133196A0
(en)
*
|
1999-11-29 |
2001-03-19 |
Yissum Res Dev Co |
Gastroretentive controlled release pharmaceutical dosage forms
|
|
MY125533A
(en)
*
|
1999-12-06 |
2006-08-30 |
Bristol Myers Squibb Co |
Heterocyclic dihydropyrimidine compounds
|
|
EP1106210A3
(de)
*
|
1999-12-07 |
2003-12-03 |
Pfizer Products Inc. |
Zusammensetzungen, für die Behandlung von diabetischen Komplikationen, welche Aldosereductasehemmern und antihypertensive Mitteln enthalten
|
|
FR2803525B1
(fr)
*
|
2000-01-06 |
2002-05-03 |
Sod Conseils Rech Applic |
Inhibiteur de la transduction des signaux des proteines g heterotrimeriques associe a un agent anti-hypertenseur dans le traitement de l'hypertension arterielle
|
|
WO2001054694A1
(en)
|
2000-01-28 |
2001-08-02 |
Bristol-Myers Squibb Company |
Tetrahydropyrimidone inhibitors of fatty acid binding protein and method
|
|
US6570013B2
(en)
|
2000-02-16 |
2003-05-27 |
Pfizer Inc |
Salts of zopolrestat
|
|
WO2001060362A1
(fr)
*
|
2000-02-18 |
2001-08-23 |
Takeda Chemical Industries, Ltd. |
INHIBITEURS DE TNF-$g(a)
|
|
WO2001060410A1
(en)
|
2000-02-21 |
2001-08-23 |
Takeda Chemical Industries, Ltd. |
Sustained release preparations of physiologically active compound hardly soluble in water and production process and use of the same
|
|
US20030152636A1
(en)
|
2000-02-23 |
2003-08-14 |
Nanopharm Ag |
Method of treating cancer
|
|
WO2001064692A1
(en)
|
2000-02-29 |
2001-09-07 |
Medicure International Inc. |
Cardioprotective phosphonates and malonates
|
|
AU2001238718A1
(en)
|
2000-03-02 |
2001-09-12 |
The Institutes For Pharmaceutical Discovery, Llc |
Compositions containing a substituted indolealkanoic acid and an angiotensin converting enzyme inhibitor
|
|
KR20070104953A
(ko)
|
2000-03-17 |
2007-10-29 |
아지노모토 가부시키가이샤 |
신경 장애용 약제
|
|
US6436684B1
(en)
|
2000-03-27 |
2002-08-20 |
Applera Corporation |
Isolated human drug-metabolizing proteins, nucleic acid molecules encoding human drug-metabolizing proteins, and uses thereof
|
|
DE10014588A1
(de)
|
2000-03-27 |
2001-10-04 |
Basf Ag |
Wirkstoffhaltige Schwimmformen enthaltend Polyvinylacetat und Polyvinylpyrrolidon, deren Verwendung und Herstellung
|
|
EP1277730A4
(de)
|
2000-03-28 |
2005-03-16 |
|
Hemmer der neovaskularisation
|
|
CA2403555A1
(en)
*
|
2000-03-28 |
2001-10-04 |
Queen's University At Kingston |
Methods for effecting neuroprotection
|
|
DE10015479A1
(de)
|
2000-03-29 |
2001-10-11 |
Basf Ag |
Feste orale Darreichungsformen mit retardierter Wirkstofffreisetzung und hoher mechanischer Stabilität
|
|
EP1267855A2
(de)
*
|
2000-04-03 |
2003-01-02 |
Bristol-Myers Squibb Company |
Vasopeptidase inhibitoren zur behandlung des isolierten, systolischen bluthochdrucks
|
|
GB0008269D0
(en)
|
2000-04-05 |
2000-05-24 |
Astrazeneca Ab |
Combination chemotherapy
|
|
GB2361185A
(en)
|
2000-04-10 |
2001-10-17 |
Nicholas J Wald |
Pharmaceutical formulation for the prevention of cardiovascular disease
|
|
US6881860B2
(en)
*
|
2000-04-11 |
2005-04-19 |
Atherogenics, Inc. |
Compounds and methods to increase plasma HDL cholesterol levels and improve HDL functionality
|
|
WO2003030868A1
(en)
|
2001-10-09 |
2003-04-17 |
Bristol-Myers Squibb Company |
Flashmelt oral dosage formulation
|
|
CA2311734C
(en)
|
2000-04-12 |
2011-03-08 |
Bristol-Myers Squibb Company |
Flash-melt oral dosage formulation
|
|
CN1440283A
(zh)
*
|
2000-04-12 |
2003-09-03 |
诺瓦提斯公司 |
有机化合物的联合形式
|
|
US20030083342A1
(en)
|
2002-08-27 |
2003-05-01 |
Steele Ronald Edward |
Combination of organic compounds
|
|
AR030557A1
(es)
|
2000-04-14 |
2003-08-27 |
Jagotec Ag |
Una tableta en multicapa de liberacion controlada y metodo de tratamiento
|
|
JP4763957B2
(ja)
*
|
2000-05-10 |
2011-08-31 |
オバン・エナジー・リミテッド |
メディアミリング
|
|
ATE310728T1
(de)
*
|
2000-05-11 |
2005-12-15 |
Bristol Myers Squibb Co |
Tetrahydroisochinolin-analoga als wachstumshormon-sekretagoga
|
|
US7229986B2
(en)
|
2000-05-16 |
2007-06-12 |
Takeda Pharmaceutical Company Ltd. |
Melanin-concentrating hormone antagonist
|
|
AU2001264729A1
(en)
*
|
2000-05-22 |
2001-12-03 |
Nitromed, Inc. |
Thromboxane inhibitors, compositions and methods of use related applications
|
|
EP1284260A4
(de)
|
2000-05-22 |
2004-03-31 |
Takeda Chemical Industries Ltd |
Tyrosin-phosphatase inhibitoren
|
|
WO2001092283A2
(en)
|
2000-05-31 |
2001-12-06 |
Mayo Foundation For Medical Education And Research |
Cobalamin compounds useful as cardiovascular agents and as imaging agents
|
|
US20030212124A1
(en)
|
2001-05-30 |
2003-11-13 |
Kevorkian Robert C. |
Use of ace inhibitors for treatment of patients suffering from behavioral disorders
|
|
US20020044962A1
(en)
|
2000-06-06 |
2002-04-18 |
Cherukuri S. Rao |
Encapsulation products for controlled or extended release
|
|
US7678387B2
(en)
|
2000-06-06 |
2010-03-16 |
Capricorn Pharma, Inc. |
Drug delivery systems
|
|
US6544981B2
(en)
*
|
2000-06-09 |
2003-04-08 |
Bristol-Myers Squibb Company |
Lactam inhibitors of factor Xa and method
|
|
US6620821B2
(en)
*
|
2000-06-15 |
2003-09-16 |
Bristol-Myers Squibb Company |
HMG-CoA reductase inhibitors and method
|
|
US6627636B2
(en)
|
2000-06-15 |
2003-09-30 |
Bristol-Myers Squibb Company |
HMG-CoA reductase inhibitors and method
|
|
US20020028826A1
(en)
*
|
2000-06-15 |
2002-03-07 |
Robl Jeffrey A. |
HMG-CoA reductase inhibitors and method
|
|
US20020013334A1
(en)
*
|
2000-06-15 |
2002-01-31 |
Robl Jeffrey A. |
HMG-CoA reductase inhibitors and method
|
|
US20020013335A1
(en)
*
|
2000-06-16 |
2002-01-31 |
American Home Products Corporation |
Method of treating cardiovascular disease
|
|
US6670355B2
(en)
|
2000-06-16 |
2003-12-30 |
Wyeth |
Method of treating cardiovascular disease
|
|
DE10029201A1
(de)
*
|
2000-06-19 |
2001-12-20 |
Basf Ag |
Verfahren zur Herstellung fester oraler Darreichungsformen mit retardierender Wirkstoffreisetzung
|
|
CA2410632A1
(en)
*
|
2000-06-22 |
2001-12-27 |
David S. Garvey |
Nitrosated and nitrosylated taxanes, compositions and methods of use
|
|
WO2002000258A1
(en)
|
2000-06-27 |
2002-01-03 |
Anges Mg, Inc. |
Medicinal compositions for angiogenic therapy
|
|
US20030114420A1
(en)
|
2000-06-28 |
2003-06-19 |
Salvati Mark E. |
Fused cyclic modulators of nuclear hormone receptor function
|
|
EP1317258B1
(de)
*
|
2000-06-28 |
2009-02-11 |
Merck & Co., Inc. |
Verwendung von allopurinol zur behandlung von bluthochdruck
|
|
US6375982B1
(en)
*
|
2000-07-05 |
2002-04-23 |
Capricorn Pharma, Inc. |
Rapid-melt semi-solid compositions, methods of making same and method of using same
|
|
WO2002002081A1
(en)
|
2000-07-05 |
2002-01-10 |
Capricorn Pharma, Inc. |
Rapid-melt semi-solid compositions, methods of making same and methods of using same
|
|
NZ523815A
(en)
|
2000-07-07 |
2004-07-30 |
Medicure Int Inc |
Pyridoxine and pyridoxal analogues: cardiovascular therapeutics
|
|
US20030176426A1
(en)
|
2000-07-13 |
2003-09-18 |
Alteon, Inc. |
Method for treating fibrotic diseases or other indications with imidazolium agents
|
|
US20020068729A1
(en)
|
2000-07-13 |
2002-06-06 |
Alteon, Inc. |
Method for treating fibrotic diseases or other indications IC
|
|
AU2001269516B2
(en)
|
2000-07-13 |
2006-09-14 |
Takeda Pharmaceutical Company Limited |
Lipid-rich plaque regressing agents
|
|
WO2002009683A2
(en)
|
2000-07-27 |
2002-02-07 |
Pharmacia Corporation |
Aldosterone blocker therapy to prevent or treat inflammation-related disorders
|
|
US6511973B2
(en)
|
2000-08-02 |
2003-01-28 |
Bristol-Myers Squibb Co. |
Lactam inhibitors of FXa and method
|
|
GB0020691D0
(en)
|
2000-08-22 |
2000-10-11 |
Boehringer Ingelheim Pharma |
Pharmaceutical combination
|
|
US7166578B2
(en)
|
2000-08-24 |
2007-01-23 |
The Regents Of The University Of California |
Orally administered peptides synergize statin activity
|
|
US6664230B1
(en)
*
|
2000-08-24 |
2003-12-16 |
The Regents Of The University Of California |
Orally administered peptides to ameliorate atherosclerosis
|
|
CA2420055C
(en)
|
2000-08-25 |
2010-06-01 |
Takeda Chemical Industries, Ltd. |
Fibrinogen-lowering agent
|
|
US6521747B2
(en)
|
2000-08-28 |
2003-02-18 |
Genaissance Pharmaceuticals, Inc. |
Haplotypes of the AGTR1 gene
|
|
AU2001284413A1
(en)
|
2000-08-30 |
2002-03-13 |
Sankyo Company Limited |
Medicinal compositions for preventing or treating heart failure
|
|
JP4969761B2
(ja)
|
2000-08-31 |
2012-07-04 |
オバン・エナジー・リミテッド |
所望粒度を持つ固体基材の小粒子および第一材料の小粒状物を含む相乗作用性混合物を製造する方法
|
|
US6576644B2
(en)
|
2000-09-06 |
2003-06-10 |
Bristol-Myers Squibb Co. |
Quinoline inhibitors of cGMP phosphodiesterase
|
|
US6595926B1
(en)
|
2000-09-07 |
2003-07-22 |
John H. Laragh |
Method for evaluating and treating hypertension
|
|
US6632180B1
(en)
|
2000-09-07 |
2003-10-14 |
John H. Laragh |
Method for evaluating and treating hypertension
|
|
US6821978B2
(en)
|
2000-09-19 |
2004-11-23 |
Schering Corporation |
Xanthine phosphodiesterase V inhibitors
|
|
US20020048599A1
(en)
|
2000-10-20 |
2002-04-25 |
Thomas H. Mueller |
Method for increasing tissue perfusion by co-administration of an agent that increases cGMP synthesis and an agent that inhibits cGMP degradation
|
|
US6841671B2
(en)
|
2000-10-26 |
2005-01-11 |
Pfizer Inc. |
Spiro-pyrimidine-2,4,6-trione metalloproteinase inhibitors
|
|
IL154946A0
(en)
|
2000-10-26 |
2003-10-31 |
Pfizer Prod Inc |
Pyrimidine-2,4,6-trione metalloproteinase inhibitors
|
|
AU2002214305A1
(en)
*
|
2000-11-17 |
2002-05-27 |
Takeda Chemical Industries Ltd. |
Pharmaceutical preparation containing copolyvidone
|
|
EP1343763A1
(de)
|
2000-11-20 |
2003-09-17 |
Bristol-Myers Squibb Company |
Pyrodon-derivate als ap2 inhibitoren
|
|
JP4107831B2
(ja)
|
2000-11-21 |
2008-06-25 |
第一三共株式会社 |
医薬組成物
|
|
AU1788502A
(en)
|
2000-11-28 |
2002-06-11 |
Univ Chicago |
Genetically engineered herpes virus for the treatment of cardiovascular disease
|
|
CA2430934C
(en)
*
|
2000-12-01 |
2011-06-21 |
Takeda Chemical Industries, Ltd. |
A method of producing sustained-release preparations of a bioactive substance using high-pressure gas
|
|
US6673802B2
(en)
|
2000-12-01 |
2004-01-06 |
Osi Pharmaceuticals, Inc. |
Compounds specific to adenosine A3 receptor and uses thereof
|
|
AU2002226365A1
(en)
|
2000-12-01 |
2002-06-11 |
Novartis Ag |
Combinations of an angiotensin receptor antagonist and an anti-hypertensive drug or a statin, for the treatment of sexual dysfunction
|
|
US20020137755A1
(en)
|
2000-12-04 |
2002-09-26 |
Bilodeau Mark T. |
Tyrosine kinase inhibitors
|
|
WO2002049630A2
(en)
|
2000-12-21 |
2002-06-27 |
Bristol-Myers Squibb Company |
Method for preventing or treating pain by administering an endothelin antagonist
|
|
ATE431830T1
(de)
|
2000-12-28 |
2009-06-15 |
Kissei Pharmaceutical |
Glucopyranosylpyrazolderivate und deren verwendung in arzneimitteln
|
|
AU2002232919A1
(en)
|
2000-12-29 |
2002-07-16 |
Alteon, Inc. |
Method for treating fibrotic diseases or other indications
|
|
MXPA03005954A
(es)
|
2000-12-29 |
2004-05-24 |
Alteon Inc |
Metodo para tratar enfermedades fibroticas u otras indicaciones iiic.
|
|
WO2002053161A1
(en)
|
2000-12-29 |
2002-07-11 |
Alteon, Inc. |
Method for treating fibrotic diseases or other indications
|
|
ITMI20010129A1
(it)
|
2001-01-25 |
2002-07-25 |
Pharmacia & Upjohn Spa |
Acidi grassi essenziali nella terapia di insufficienza cardiaca e scompenso cardiaco
|
|
IL156585A0
(en)
|
2001-01-26 |
2004-01-04 |
Schering Corp |
Combinations of sterol absorption inhibitor(s) with cardiovascular agent(s) for the treatment of vascular conditions
|
|
PL364178A1
(en)
|
2001-01-26 |
2004-12-13 |
Schering Corporation |
Combinations of sterol absorption inhibitor(s) with blood modifier(s) for treating vascular conditions
|
|
US20020183305A1
(en)
|
2001-01-26 |
2002-12-05 |
Schering Corporation |
Combinations of nicotinic acid and derivatives thereof and sterol absorption inhibitor(s) and treatments for vascular indications
|
|
HU230253B1
(hu)
|
2001-01-26 |
2015-11-30 |
Merck Sharp & Dohme Corp |
Peroxiszóma proliferátor-aktivált receptor (PPAR) aktivátor(ok) és szterin-abszorpció inhibitor(ok) kombinációi és alkalmazásuk vaszkuláris indikációk kezelésére
|
|
AU2002241956A1
(en)
*
|
2001-01-26 |
2002-08-06 |
Schering Corporation |
Combinations of bile acid sequestrant(s) and sterol absorption inhibitor(s) and treatments for vascular indications
|
|
JP2004518688A
(ja)
|
2001-01-30 |
2004-06-24 |
ブリストル−マイヤーズ スクイブ カンパニー |
ファクターXa阻害剤のスルホンアミドラクタムおよびその方法
|
|
TWI255817B
(en)
|
2001-02-14 |
2006-06-01 |
Kissei Pharmaceutical |
Glucopyranosyloxybenzylbenzene derivatives and medicinal use thereof
|
|
FI114483B
(fi)
*
|
2001-02-20 |
2004-10-29 |
Jurilab Ltd Oy |
Menetelmä kohonneen verenpaineen riskin osoittamiseksi ja sen käytöt
|
|
US7087579B2
(en)
|
2001-02-26 |
2006-08-08 |
Kissei Pharmaceutical Co., Ltd. |
Glucopyranosyloxypyrazole derivatives and medicinal use thereof
|
|
JP4147111B2
(ja)
|
2001-02-27 |
2008-09-10 |
キッセイ薬品工業株式会社 |
グルコピラノシルオキシピラゾール誘導体およびその医薬用途
|
|
ATE297902T1
(de)
*
|
2001-02-28 |
2005-07-15 |
Pfizer Prod Inc |
Sulfonyl-pyridazinon-derivate zur verwendung als aldose-reduktase-inhibitoren
|
|
US20030119010A1
(en)
|
2001-03-01 |
2003-06-26 |
University Of Queensland |
Polynucleotides and polypeptides linked to a disease or condition
|
|
EP1370211A4
(de)
|
2001-03-02 |
2005-02-09 |
Bristol Myers Squibb Co |
Gleichzeitige verabreichung eines melanocortin rezeptor-agonists und eines phosphodiesterase-hemmers zur behandlung von erkrankungen im zusammenhang mit zyklischer amp
|
|
CA2438272A1
(en)
|
2001-03-02 |
2002-10-10 |
John Macor |
Compounds useful as modulators of melanocortin receptors and pharmaceutical compositions comprising same
|
|
US6936590B2
(en)
|
2001-03-13 |
2005-08-30 |
Bristol Myers Squibb Company |
C-aryl glucoside SGLT2 inhibitors and method
|
|
US6642244B2
(en)
|
2001-03-16 |
2003-11-04 |
Bristol-Myers Squibb Co. |
Pyrazolopyridopyrimidine inhibitors of cGMP phosphodiesterase
|
|
EP1491541B1
(de)
|
2001-03-30 |
2007-01-24 |
Pfizer Products Inc. |
Pyridazinon Aldose Reductase Inhibitoren
|
|
EP1247809A3
(de)
*
|
2001-03-30 |
2003-12-17 |
Pfizer Products Inc. |
Triazin-Verbindungen und ihre Verwendung als Hemmer der Sorbit-Dehydrogenase
|
|
AU2002254567B2
(en)
|
2001-04-11 |
2007-10-11 |
Bristol-Myers Squibb Company |
Amino acid complexes of C-aryl glucosides for treatment of diabetes and method
|
|
US20030004199A1
(en)
*
|
2001-04-12 |
2003-01-02 |
Isabelle Ounis |
Method for preventing or treating pulmonary inflammation by administering an endothelin antagonist
|
|
US7235523B2
(en)
|
2001-04-13 |
2007-06-26 |
Children's Hospital Medical Center |
Methods for the treatment of hepatic disorders
|
|
WO2002087503A2
(en)
|
2001-04-26 |
2002-11-07 |
Vanderbilt University |
Compositions and methods for treating colorectal polyps and cancer
|
|
WO2002087508A2
(en)
|
2001-05-02 |
2002-11-07 |
Nitromed, Inc. |
Nitrosated and nitrosylated nebivolol and its metabolites, compositions and methods of use
|
|
US20020168393A1
(en)
|
2001-05-08 |
2002-11-14 |
Ryota Sugimoto |
Implantable medical material and implantable medical device
|
|
US20030073705A1
(en)
|
2001-05-14 |
2003-04-17 |
Shahnaz Shahinfar |
Method of treatment
|
|
US6777443B2
(en)
|
2001-05-15 |
2004-08-17 |
Novartis Ag |
Dipeptide derivatives
|
|
US20030078190A1
(en)
|
2001-05-25 |
2003-04-24 |
Weinberg Marc S. |
Methods for tissue protection using highly effective inhibition of the renin-angiotensin system
|
|
US20030060451A1
(en)
*
|
2001-05-29 |
2003-03-27 |
Rajneesh Taneja |
Enhancement of oral bioavailability of non-emulsified formulations of prodrug esters with lecithin
|
|
JP2004532862A
(ja)
*
|
2001-05-30 |
2004-10-28 |
アルテオン インコーポレイテッド |
線維性疾患又は他の適応症の治療方法
|
|
EP1406611A2
(de)
*
|
2001-05-30 |
2004-04-14 |
Alteon, Inc. |
Behandlungsmethode für fibrotische erkrankungen oder andere indikationen
|
|
US20030092736A1
(en)
|
2001-05-30 |
2003-05-15 |
Cheng Peter T. |
Substituted azole acid derivatives useful as antidiabetic and antiobesity agents and method
|
|
US7105556B2
(en)
|
2001-05-30 |
2006-09-12 |
Bristol-Myers Squibb Company |
Conformationally constrained analogs useful as antidiabetic and antiobesity agents and method
|
|
US6967212B2
(en)
|
2001-05-30 |
2005-11-22 |
Bristol-Myers Squibb Company |
Substituted azole acid derivatives useful as antidiabetic and antiobesity agents and method
|
|
US20040156903A1
(en)
|
2002-05-22 |
2004-08-12 |
Abrams Andrew L.. |
Metering and packaging of controlled release medication
|
|
KR100988542B1
(ko)
|
2001-06-18 |
2010-10-20 |
노벤 파머수티컬즈, 인코퍼레이티드 |
경피 시스템에서의 강화된 약물 전달
|
|
WO2003006023A1
(en)
*
|
2001-07-13 |
2003-01-23 |
Bristol-Myers Squibb Company |
Pyrazinone inhibitors of fatty acid binding protein and method
|
|
US20030158090A1
(en)
|
2001-07-23 |
2003-08-21 |
Ulrik Pedersen-Bjergaard |
Renin-angiotensin system in diabetes mellitus
|
|
WO2003011824A1
(en)
*
|
2001-07-31 |
2003-02-13 |
Bristol-Myers Squibb Company |
Bicyclic modulators of androgen receptor function
|
|
WO2003015715A2
(en)
|
2001-08-20 |
2003-02-27 |
Bristol-Myers Squibb Company |
Tetrahydroquinoline derivatives as antithrombotic agents
|
|
US20030083286A1
(en)
|
2001-08-22 |
2003-05-01 |
Ching-Leou Teng |
Bioadhesive compositions and methods for enhanced intestinal drug absorption
|
|
US20030124196A1
(en)
|
2001-08-22 |
2003-07-03 |
Susan Weinbach |
Pulsatile release compositions and methods for enhanced intestinal drug absorption
|
|
US6576256B2
(en)
*
|
2001-08-28 |
2003-06-10 |
The Brigham And Women's Hospital, Inc. |
Treatment of patients at elevated cardiovascular risk with a combination of a cholesterol-lowering agent, an inhibitor of the renin-angiotensin system, and aspirin
|
|
ATE395349T1
(de)
|
2001-08-28 |
2008-05-15 |
Schering Corp |
Polycyclische guanin phosphodiesterase inhibitoren
|
|
US6669955B2
(en)
|
2001-08-28 |
2003-12-30 |
Longwood Pharmaceutical Research, Inc. |
Combination dosage form containing individual dosage units of a cholesterol-lowering agent, an inhibitor of the renin-angiotensin system, and aspirin
|
|
WO2003020737A1
(en)
|
2001-09-05 |
2003-03-13 |
Bristol-Myers Squibb Company |
O-pyrazole glucoside sglt2 inhibitors and method of use
|
|
US20030050620A1
(en)
*
|
2001-09-07 |
2003-03-13 |
Isa Odidi |
Combinatorial type controlled release drug delivery device
|
|
WO2003023066A1
(en)
|
2001-09-11 |
2003-03-20 |
The Regents Of The University Of Colorado, A Body Corporate |
Expression profiling in the intact human heart
|
|
US6638542B2
(en)
|
2001-09-20 |
2003-10-28 |
Nutricia N.V. |
Reducing appetite in mammals by administering procyanidin and hydroxycitric acid
|
|
US7056906B2
(en)
|
2001-09-21 |
2006-06-06 |
Schering Corporation |
Combinations of hormone replacement therapy composition(s) and sterol absorption inhibitor(s) and treatments for vascular conditions in post-menopausal women
|
|
TWI320039B
(en)
|
2001-09-21 |
2010-02-01 |
|
Lactam-containing compounds and derivatives thereof as factor xa inhibitors
|
|
US20030119808A1
(en)
|
2001-09-21 |
2003-06-26 |
Schering Corporation |
Methods of treating or preventing cardiovascular conditions while preventing or minimizing muscular degeneration side effects
|
|
US7053080B2
(en)
|
2001-09-21 |
2006-05-30 |
Schering Corporation |
Methods and therapeutic combinations for the treatment of obesity using sterol absorption inhibitors
|
|
US20030114469A1
(en)
|
2001-09-27 |
2003-06-19 |
Cohen David Saul |
Combinations
|
|
US7019010B2
(en)
|
2001-09-27 |
2006-03-28 |
Novertis Ag |
Combinations
|
|
EP1298223A3
(de)
|
2001-09-28 |
2003-07-23 |
Pfizer Products Inc. |
Methoden die mit der A-C Wiederholungs-Z-Sequenz stromaufwärts des Aldosereduktasegens in Zusammenhang stehen
|
|
JP2005508332A
(ja)
|
2001-09-28 |
2005-03-31 |
メイオウ・フアウンデーシヨン・フオー・メデイカル・エジユケイシヨン・アンド・リサーチ |
薬剤を送達するための、輸送タンパク質とコンジュゲートコバラミンとの同時投与
|
|
US20030134810A1
(en)
|
2001-10-09 |
2003-07-17 |
Chris Springate |
Methods and compositions comprising biocompatible materials useful for the administration of therapeutic agents
|
|
US6592901B2
(en)
|
2001-10-15 |
2003-07-15 |
Hercules Incorporated |
Highly compressible ethylcellulose for tableting
|
|
KR20040054729A
(ko)
|
2001-10-18 |
2004-06-25 |
브리스톨-마이어스 스큅 컴퍼니 |
인간 글루카곤-유사-펩티드-1 모방체, 및 당뇨병 및 이와관련된 증상의 치료에 있어서 이의 용도
|
|
US20030152622A1
(en)
|
2001-10-25 |
2003-08-14 |
Jenny Louie-Helm |
Formulation of an erodible, gastric retentive oral diuretic
|
|
US20030091630A1
(en)
|
2001-10-25 |
2003-05-15 |
Jenny Louie-Helm |
Formulation of an erodible, gastric retentive oral dosage form using in vitro disintegration test data
|
|
FR2831446B1
(fr)
|
2001-10-26 |
2004-03-05 |
Sanofi Synthelabo |
Utilisation de l'irbesartan pour la preparation de medicaments utiles pour la prevention ou le traitement de l'hypertension pulmonaire
|
|
AU2916902A
(en)
|
2001-10-29 |
2003-05-01 |
Caritas St. Elizabeth's Medical Center Of Boston, Inc. |
Glycogen synthase kinase function in endothelial cells
|
|
US20030083614A1
(en)
|
2001-10-30 |
2003-05-01 |
Boehringer Ingelheim Pharma Kg |
Controlled release endoprosthetic device
|
|
US20030195205A1
(en)
|
2001-11-02 |
2003-10-16 |
Pfizer Inc. |
PDE9 inhibitors for treating cardiovascular disorders
|
|
EP1442028A4
(de)
*
|
2001-11-06 |
2009-11-04 |
Bristol Myers Squibb Co |
Substituierte säurederivate, die sich als antidiabetika und mittel gegen obesitas eignen, und verfahren
|
|
CA2465893A1
(en)
|
2001-11-09 |
2003-05-22 |
Schering Corporation |
Polycyclic guanine derivative phosphodiesterase v inhibitors
|
|
DE60222693T2
(de)
|
2001-11-13 |
2008-07-17 |
Schering Corp. |
Nk1-antagonisten
|
|
US7361671B2
(en)
|
2001-11-15 |
2008-04-22 |
The Institute For Pharmaceutical Discovery, Inc. |
Substituted heteroarylalkanoic acids
|
|
AU2002348276A1
(en)
|
2001-11-16 |
2003-06-10 |
Bristol-Myers Squibb Company |
Dual inhibitors of adipocyte fatty acid binding protein and keratinocyte fatty acid binding protein
|
|
US20030206978A1
(en)
|
2001-11-29 |
2003-11-06 |
Bob Sherwood |
Agglomerated particles including an active agent coprocessed with silicified microcrystalline cellulose
|
|
TW200303309A
(en)
|
2001-12-04 |
2003-09-01 |
Bristol Myers Squibb Co |
Novel n-[4-(1h-imidazol-1-yl)-2-fluorophenyl]-3-trifluoromethyl)-1h-pyrazole-5-carboxamides as factor Xa inhibitors
|
|
WO2003048081A2
(en)
|
2001-12-04 |
2003-06-12 |
Bristol-Myers Squibb Company |
Glycinamides as factor xa inhibitors
|
|
TW200302225A
(en)
|
2001-12-04 |
2003-08-01 |
Bristol Myers Squibb Co |
Substituted amino methyl factor Xa inhibitors
|
|
US6831102B2
(en)
|
2001-12-07 |
2004-12-14 |
Bristol-Myers Squibb Company |
Phenyl naphthol ligands for thyroid hormone receptor
|
|
US20050176793A1
(en)
|
2001-12-10 |
2005-08-11 |
Reddy Reguri B. |
Amorphous form of 2-n-butyl-3-((2-(1h-tetrazol-5-yl)([1,1'-biphenyl)-4-yl)methyl)-1, 3-diazaspiro(4,4')non-1-en-4-one
|
|
PE20030762A1
(es)
|
2001-12-18 |
2003-09-05 |
Schering Corp |
Compuestos heterociclicos como antagonistas nk1
|
|
US7087636B2
(en)
|
2001-12-19 |
2006-08-08 |
Bristol-Myers Squibb Company |
Fused heterocyclic compounds and analogs thereof, modulators of nuclear hormone receptor function
|
|
WO2003053353A2
(en)
|
2001-12-20 |
2003-07-03 |
Bristol-Myers Squibb Company |
Administration of vasopeptidase inhibitors to reduce pulse pressure
|
|
ATE374602T1
(de)
|
2001-12-21 |
2007-10-15 |
Supernus Pharmaceuticals Inc |
Orale kapselformulierung mit verbesserter physikalischer stabilität
|
|
ES2280596T3
(es)
|
2001-12-29 |
2007-09-16 |
Novo Nordisk A/S |
Uso combinado de un compuesto de glp-1 y un inhibidor de una aldosa reductasa.
|
|
PT1478648E
(pt)
|
2002-02-01 |
2014-07-15 |
Ariad Pharma Inc |
Compostos contendo fósforo e suas utilizações
|
|
WO2003065997A2
(en)
|
2002-02-06 |
2003-08-14 |
Vicor Technologies, Inc. |
Anti-infarction molecules
|
|
US20030221207A1
(en)
|
2002-02-13 |
2003-11-27 |
Pharmacia Corporation, Global Patent Department |
Cardiac-specific 11beta hydroxysteroid dehydrogenase type 2 transgenic mice
|
|
WO2003070278A1
(en)
|
2002-02-19 |
2003-08-28 |
Boehringer Ingelheim International Gmbh |
Pharmaceutical combination of angiotensin ii antagonists and angiotensin i converting enzyme inhibitors
|
|
AU2002367730A1
(en)
|
2002-02-26 |
2003-09-09 |
Stephen L. Schlesinger |
Use of leukotriene receptor antagonist for treatment of scarring
|
|
CN1642599A
(zh)
|
2002-02-27 |
2005-07-20 |
辉瑞产品公司 |
Acc抑制剂
|
|
US20040116510A1
(en)
|
2002-03-05 |
2004-06-17 |
Nichtberger Steven A. |
Antihypertensive agent and cholesterol absorption inhibitor combination therapy
|
|
US20030215526A1
(en)
|
2002-03-08 |
2003-11-20 |
Scott Stofik |
Stable formulations of angiotensin converting enzyme (ACE) inhibitors
|
|
JP2005526769A
(ja)
|
2002-03-15 |
2005-09-08 |
ザ・ブリガーム・アンド・ウーメンズ・ホスピタル・インコーポレーテッド |
治療剤を全身搬送するための中央気道投与
|
|
CA2478653A1
(en)
|
2002-03-18 |
2003-09-25 |
Pfizer Products Inc. |
Methods of treatment with selective ep4 receptor agonists
|
|
AU2003209851A1
(en)
|
2002-03-20 |
2003-09-29 |
The University Of Queensland |
Method of treatment and/or prophylaxis
|
|
CA2480082A1
(en)
*
|
2002-03-29 |
2003-10-16 |
Neurogen Corporation |
Combination therapy for the treatment of conditions with pathogenic inflammatory components
|
|
AU2003223491A1
(en)
|
2002-04-05 |
2003-10-27 |
Nitromed, Inc. |
Nitric oxide donors, compositions and methods of use
|
|
US6930085B2
(en)
|
2002-04-05 |
2005-08-16 |
The Regents Of The University Of California |
G-type peptides to ameliorate atherosclerosis
|
|
US20040005358A1
(en)
*
|
2002-04-23 |
2004-01-08 |
Slugg Peter H. |
Modified-release vasopeptidase inhibitor formulation, combinations and method
|
|
KR20040104632A
(ko)
*
|
2002-04-26 |
2004-12-10 |
쉐링 악티엔게젤샤프트 |
호르몬 대체 요법을 받는 여성에서 고혈압의 치료
|
|
JP2005529889A
(ja)
|
2002-04-26 |
2005-10-06 |
ファイザー・プロダクツ・インク |
ピリミジン−2,4,6−トリオンメタロ−プロテイナーゼ阻害剤
|
|
NI200300045A
(es)
*
|
2002-04-26 |
2005-07-08 |
Pfizer Prod Inc |
Inhibidores de triariloxiariloxipirimidin-2,4,6-triona de metaloproteinasa.
|
|
AU2003216660A1
(en)
*
|
2002-04-26 |
2003-11-10 |
Pfizer Products Inc. |
N-substituted-heteroaryloxy-aryl-spiro-pyrimidine-2,4,6-trione metalloproteinase inhibitors
|
|
AU2003219410A1
(en)
|
2002-04-26 |
2003-11-10 |
Pfizer Products Inc. |
Triaryl-oxy-aryl-spiro-pyrimidine-2, 4, 6-trione metalloproteinase inhibitors
|
|
US20030203027A1
(en)
|
2002-04-26 |
2003-10-30 |
Ethicon, Inc. |
Coating technique for deposition of drug substance on a substrate
|
|
US20030203019A1
(en)
|
2002-04-30 |
2003-10-30 |
Cornelius John Mark |
Coated conditioners for use in foods and pharmaceuticals
|
|
TW200307667A
(en)
*
|
2002-05-06 |
2003-12-16 |
Bristol Myers Squibb Co |
Sulfonylaminovalerolactams and derivatives thereof as factor Xa inhibitors
|
|
US7276514B2
(en)
|
2002-05-15 |
2007-10-02 |
Charitable Leadership Foundation - Medical Technology Acceleration Program |
Pyrroloquinoline quinone drugs for treatment of cardiac injury and methods of use thereof
|
|
AUPS236902A0
(en)
|
2002-05-16 |
2002-06-13 |
Northern Sydney Area Health Service |
Composition and method for treating hypertension
|
|
TW200407324A
(en)
*
|
2002-05-17 |
2004-05-16 |
Bristol Myers Squibb Co |
Bicyclic modulators of androgen receptor function
|
|
US7375138B2
(en)
|
2002-05-18 |
2008-05-20 |
Sanofi-Aventis Deutschland Gmbh |
Pentafluorosulfanylbenzoylguanidines, processes for their preparation, their use as medicaments or diagnostic aids, and medicaments comprising them
|
|
US7057046B2
(en)
*
|
2002-05-20 |
2006-06-06 |
Bristol-Myers Squibb Company |
Lactam glycogen phosphorylase inhibitors and method of use
|
|
AU2003239508A1
(en)
|
2002-05-21 |
2003-12-12 |
Bristol-Myers Squibb Company |
Indole compounds useful as impdh inhibitors
|
|
US20030229007A1
(en)
|
2002-05-30 |
2003-12-11 |
Roberto Levi |
Form of human renin and its use as a target in treatments for cardiac ischemia and arrhythmia
|
|
JP2005529933A
(ja)
|
2002-05-31 |
2005-10-06 |
シェーリング コーポレイション |
キサンチンホスホジエステラーゼvインヒビター多形体
|
|
US20030233118A1
(en)
|
2002-06-13 |
2003-12-18 |
Hui John C. K. |
Method for treating congestive heart failure using external counterpulsation
|
|
US7049333B2
(en)
*
|
2002-06-04 |
2006-05-23 |
Sanofi-Aventis Deutschland Gmbh |
Substituted thiophenes: compositions, processes of making, and uses in disease treatment and diagnosis
|
|
WO2003101431A1
(en)
|
2002-06-04 |
2003-12-11 |
J.B. Chemicals & Pharmaceuticals Ltd. |
Pharmaceutical composition for controlled drug delivery system
|
|
JP4533134B2
(ja)
|
2002-06-10 |
2010-09-01 |
エラン ファーマ インターナショナル,リミティド |
ナノ粒子ポリコサノール製剤および新規なポリコサノールの組合せ
|
|
US20040009972A1
(en)
*
|
2002-06-17 |
2004-01-15 |
Ding Charles Z. |
Benzodiazepine inhibitors of mitochondial F1F0 ATP hydrolase and methods of inhibiting F1F0 ATP hydrolase
|
|
US6846838B2
(en)
*
|
2002-06-19 |
2005-01-25 |
Bristol-Myers Squibb Company |
Ureido-substituted aniline compounds useful as serine protease inhibitors
|
|
EP1382334A1
(de)
|
2002-07-11 |
2004-01-21 |
Université de Picardie Jules Verne |
Verwendung von Angiotensin II AT1-Rezeptorblockern, allein oder in Kombination mit Thiazide oder Angiotensin II zur Behandlung von Schlaganfall
|
|
US20040138306A1
(en)
|
2002-07-25 |
2004-07-15 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Use of a specific cyclic amine derivative or the pharmaceutically acceptable salts thereof for the treatment or prevention of heart failure
|
|
US7985422B2
(en)
|
2002-08-05 |
2011-07-26 |
Torrent Pharmaceuticals Limited |
Dosage form
|
|
AU2003279842A1
(en)
|
2002-10-04 |
2004-05-04 |
Microchips, Inc. |
Medical device for controlled drug delivery and cardiac monitoring and/or stimulation
|
|
US20040106954A1
(en)
|
2002-11-15 |
2004-06-03 |
Whitehurst Todd K. |
Treatment of congestive heart failure
|
|
US7268157B2
(en)
|
2002-11-26 |
2007-09-11 |
Shenzhen Chipscreen Biosciences, Ltd. |
Substituted arylalcanoic acid derivatives as PPAR pan agonists with potent antihyperglycemic and antihyperlipidemic activity
|