ATE494913T1 - Kontrastmittel für eine extrazelluläre matrix - Google Patents

Kontrastmittel für eine extrazelluläre matrix

Info

Publication number
ATE494913T1
ATE494913T1 AT05817391T AT05817391T ATE494913T1 AT E494913 T1 ATE494913 T1 AT E494913T1 AT 05817391 T AT05817391 T AT 05817391T AT 05817391 T AT05817391 T AT 05817391T AT E494913 T1 ATE494913 T1 AT E494913T1
Authority
AT
Austria
Prior art keywords
extracellular matrix
contrast agents
biomodifier
areas
human
Prior art date
Application number
AT05817391T
Other languages
English (en)
Inventor
Dagfinn Lyvhaug
Morten Eriksen
Hege B Fjerdingstad
Andrew Healey
Original Assignee
Ge Healthcare As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ge Healthcare As filed Critical Ge Healthcare As
Application granted granted Critical
Publication of ATE494913T1 publication Critical patent/ATE494913T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10—Organic compounds
    • A61K49/14—Peptides, e.g. proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/005—Fluorescence in vivo characterised by the carrier molecule carrying the fluorescent agent
    • A61K49/0056—Peptides, proteins, polyamino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/0002—General or multifunctional contrast agents, e.g. chelated agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • A61K49/0032—Methine dyes, e.g. cyanine dyes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/085—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier conjugated systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0497—Organic compounds conjugates with a carrier being an organic compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Optics & Photonics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Steroid Compounds (AREA)
AT05817391T 2004-11-22 2005-11-21 Kontrastmittel für eine extrazelluläre matrix ATE494913T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NO20045081 2004-11-22
PCT/NO2005/000435 WO2006054904A2 (en) 2004-11-22 2005-11-21 Contrast agents to target extracellular matrix

Publications (1)

Publication Number Publication Date
ATE494913T1 true ATE494913T1 (de) 2011-01-15

Family

ID=36182407

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05817391T ATE494913T1 (de) 2004-11-22 2005-11-21 Kontrastmittel für eine extrazelluläre matrix

Country Status (17)

Country Link
US (1) US8182790B2 (de)
EP (2) EP2243496A3 (de)
JP (2) JP5116480B2 (de)
KR (1) KR20070091609A (de)
CN (1) CN101107016B (de)
AT (1) ATE494913T1 (de)
AU (1) AU2005307195A1 (de)
BR (1) BRPI0518328A2 (de)
CA (1) CA2586621A1 (de)
DE (1) DE602005025911D1 (de)
ES (1) ES2358745T3 (de)
IL (1) IL182898A0 (de)
MX (1) MX2007006050A (de)
NO (1) NO20073039L (de)
RU (1) RU2007118385A (de)
WO (1) WO2006054904A2 (de)
ZA (1) ZA200705043B (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0610395D0 (en) * 2006-05-25 2006-07-05 Ge Healthcare Ltd Novel imaging agents
EP2056886A2 (de) * 2006-08-28 2009-05-13 GE Healthcare Limited 68ga-markierte radiopharmazeutika auf peptidbasis
JP2008266194A (ja) * 2007-04-19 2008-11-06 Hiroshi Tanaka 分子プローブの原料として有用な新規有機化合物
GB0722650D0 (en) * 2007-11-19 2007-12-27 Ge Healthcare Ltd Novel imaging method
JP5604305B2 (ja) 2007-12-13 2014-10-08 アンセルム（アンスチチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル） 線維症の非侵襲性の特異的イメージングのための、ポリペプチド、環状ポリペプチドおよびそれを含む医薬
US8815214B2 (en) * 2008-01-18 2014-08-26 Visen Medical, Inc. Fluorescent imaging agents
CN102088991A (zh) 2008-05-13 2011-06-08 堪萨斯大学 金属提取肽标签和相关方法
GB0814722D0 (en) * 2008-08-12 2008-09-17 Ge Healthcare Ltd Treatment monitoring
GB0910013D0 (en) * 2009-06-10 2009-07-22 Ge Healthcare Ltd PET imaging of fibogenesis
KR100991716B1 (ko) * 2009-10-22 2010-11-04 경북대학교 산학협력단 광학영상 조영제, 그 용도 및 장치
CN102504603B (zh) * 2011-10-20 2014-01-29 中国海洋大学 一种多聚物与生物染色剂的偶合物及其制备方法和用途
US9187735B2 (en) 2012-06-01 2015-11-17 University Of Kansas Metal abstraction peptide with superoxide dismutase activity
WO2015085005A1 (en) * 2013-12-03 2015-06-11 The General Hospital Corporation Molecular imaging probes
CN117623996B (zh) * 2022-08-10 2025-07-22 中国药科大学 一种二价keap1-nrf2抑制剂、制备方法及其医药用途

Family Cites Families (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4647447A (en) 1981-07-24 1987-03-03 Schering Aktiengesellschaft Diagnostic media
US4615876A (en) * 1983-04-25 1986-10-07 Curators Of The University Of Missouri Macrocyclic complexes of technetium-99m for use as diagnostic radionuclides
US4687659A (en) 1984-11-13 1987-08-18 Salutar, Inc. Diamide-DTPA-paramagnetic contrast agents for MR imaging
US5268486A (en) 1986-04-18 1993-12-07 Carnegie-Mellon Unversity Method for labeling and detecting materials employing arylsulfonate cyanine dyes
US6048982A (en) 1986-04-18 2000-04-11 Carnegie Mellon University Cyanine dyes as labeling reagents for detection of biological and other materials by luminescence methods
ATE145337T1 (de) 1988-05-02 1996-12-15 Phanos Tech Inc Verbindungen, zusammensetzungen und verfahren zum binden von bio-affektions-substanzen an oberflächenmembranen von bioteilchen
GB8903022D0 (en) * 1989-02-10 1989-03-30 Celltech Ltd Chemical compounds
EP0643706A1 (de) 1991-11-27 1995-03-22 Zynaxis Inc. Verbindungen, zusammensetzungen und methoden um biologisch aktive substanzen anoberfl chenmembrane von biopartikeln zu binden
DE69735901T2 (de) 1996-10-28 2007-05-10 Ge Healthcare As Verbesseringen an oder in verbindung mit diagnostischen/therapeutischen mitteln
ATE314097T1 (de) 1996-10-28 2006-01-15 Amersham Health As Kontrastmittel
JP2001509796A (ja) * 1997-01-29 2001-07-24 ニユコメド・イメージング・アクシエセルカペト 重合体
EP1037947B1 (de) 1997-07-28 2003-09-10 Amersham plc Cyaninfarbstoffe
US5942637A (en) * 1998-03-30 1999-08-24 North Dakota State University Research Foundation Compounds containing tetradecachlorocyclohexasilane dianion
US6852318B1 (en) * 1998-05-08 2005-02-08 The Regents Of The University Of California Methods for detecting and inhibiting angiogenesis
WO1999058139A2 (en) * 1998-05-08 1999-11-18 The Regents Of The University Of California Methods for detecting and inhibiting angiogenesis
JP2000095758A (ja) * 1998-09-18 2000-04-04 Schering Ag 近赤外蛍光造影剤および蛍光造影方法
US6230777B1 (en) 1999-02-04 2001-05-15 Midmac Systems, Inc. Filter forming and joining apparatus
CA2405469C (en) * 2000-04-12 2012-03-20 Amersham Health As Integrin binding peptide derivatives
NO20004795D0 (no) * 2000-09-26 2000-09-26 Nycomed Imaging As Peptidbaserte forbindelser
EP1337278A2 (de) * 2000-11-27 2003-08-27 Bristol-Myers Squibb Medical Imaging, Inc. Gleichzeitiges imaging der kardialen perfusion und eines auf den vitronektin rezeptor zielgerichteten agens
BRPI0210886B8 (pt) * 2001-07-10 2021-05-25 Amersham Health As composto, composição farmacêutica, uso de um composto, e, métodos de geração de imagens, de monitoração do efeito do tratamento de um corpo humano ou animal com uma droga para combater uma condição associada com câncer e de tratamento de câncer ou de uma doença relacionada em um corpo humano ou animal
GB0116815D0 (en) 2001-07-10 2001-08-29 Nycomed Amersham Plc Improved chelator conjugates
GB0206750D0 (en) 2002-03-22 2002-05-01 Amersham Plc Radiofluorination methods
JP2006510576A (ja) 2002-06-17 2006-03-30 カルテラ、アクチボラグ アテローム性動脈硬化症のプラーク形成の進行を防止するためのインテグリンα１０鎖の方法および使用
US7063158B2 (en) 2003-06-16 2006-06-20 Deepwater Technologies, Inc. Bottom tensioned offshore oil well production riser
NO20033115D0 (no) * 2003-07-08 2003-07-08 Amersham Health As Peptid-baserte forbindelser
GB0317815D0 (en) 2003-07-30 2003-09-03 Amersham Health As Imaging agents
WO2005019247A2 (en) 2003-08-15 2005-03-03 Board Of Regents, The University Of Texas System Cyclic peptide and imaging compound compositions and uses for targeted imaging and therapy
JP2007512321A (ja) * 2003-11-24 2007-05-17 ジーイー・ヘルスケア・アクスイェ・セルスカプ 造影剤
ATE447417T1 (de) * 2004-03-04 2009-11-15 Ge Healthcare As Konjugate von angiotensin-peptid analoga und chelatbildner für diagnose und therapie
RU2393167C2 (ru) * 2004-06-16 2010-06-27 Джи-И Хелткер АС Пептидные соединения
JP5280682B2 (ja) * 2004-06-16 2013-09-04 ジーイー・ヘルスケア・アクスイェ・セルスカプ ペプチド系化合物

Also Published As

Publication number Publication date
EP1814598A2 (de) 2007-08-08
EP2243496A2 (de) 2010-10-27
MX2007006050A (es) 2007-11-14
JP5116480B2 (ja) 2013-01-09
EP1814598B1 (de) 2011-01-12
WO2006054904A2 (en) 2006-05-26
NO20073039L (no) 2007-08-16
JP2008520658A (ja) 2008-06-19
US8182790B2 (en) 2012-05-22
KR20070091609A (ko) 2007-09-11
IL182898A0 (en) 2007-08-19
EP2243496A3 (de) 2012-12-26
ZA200705043B (en) 2008-09-25
CA2586621A1 (en) 2006-05-26
BRPI0518328A2 (pt) 2008-11-11
DE602005025911D1 (de) 2011-02-24
US20090208412A1 (en) 2009-08-20
WO2006054904A3 (en) 2007-04-05
JP2012207027A (ja) 2012-10-25
ES2358745T3 (es) 2011-05-13
AU2005307195A1 (en) 2006-05-26
RU2007118385A (ru) 2008-12-27
CN101107016A (zh) 2008-01-16
CN101107016B (zh) 2011-11-16

Similar Documents

Publication Publication Date Title
IL182898A0 (en) Contrast agents
DE60042522D1 (de) Cyanin- oder indocyaninefarbstoffe biokonjugate für biomedische anwendungen
ECSP066311A (es) Derivados de la piperazina y su uso como agentes terapéuticos
CY1110505T1 (el) Ανθρωπινα αντισωματα dr4 και χρησεις αυτων
ATE530168T1 (de) Magnetische nanoteilchen-zusammensetzungen und ihre verwendungen
CY1109151T1 (el) Αντισωματα dr4 και χρησεις αυτων
WO2003049684A3 (en) Pseudo-antibody constructs
ATE445838T1 (de) Zusammensetzungen und verfahren zur modulation des transports durch die blut-hirn-schranke
DE69837975D1 (de) Diagnostisches Abbildungsverfahren
ATE439868T1 (de) Targetingmittel für molekulare bilderzeugung
BRPI0418552A (pt) compostos de alvejamento de piperidinila que seletivamente ligam-se à integrinas
EP1250095A4 (de) Vielseitige hydrophile farbstoffe
DE50207866D1 (de) Verwendung löslicher cytokeratin-1-fragmente in diagnostik
FR2870731B1 (fr) Composition pour la coloration des fibres keratiniques comprenant un pigment et des polymeres aptes a reagir l'un avec l'autre pour former des liaisons covalentes
ATE425770T1 (de) Kontrastmittel
DE50101479D1 (de) Fluoresceinisothiocyanat-(fitc)-sinistrin, seine herstellung und verwendung
AR027575A1 (es) Benzoilciclohexenonas substituidas
DE602008004556D1 (de) Zusammensetzungen und verfahren zum nachweis von störungen in verbindung mit histamin
WO2005049095A3 (en) Contrast agent imaging angiotensin ii receptors
ATE480552T1 (de) Stq-peptide
ATE392183T1 (de) Hydrophile zyaninfarbstoffe
ATE306283T1 (de) Biotin-derivate und ihre konjugaten mit chelatierungsmitteln
FR2836382B1 (fr) Nouveaux agents de couplages, leurs conjugues, ainsi que l'utilisation de ces conjugues dans des methodes de diagnostic
WO2006027244A3 (en) Paramagnetic metal polyamino complexes for mri visualization of internalized polynucleotides

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties