ATE496025T1 - Magnesiumsalze von hmg-coa-reduktase-hemmern - Google Patents
Magnesiumsalze von hmg-coa-reduktase-hemmernInfo
- Publication number
- ATE496025T1 ATE496025T1 AT06765662T AT06765662T ATE496025T1 AT E496025 T1 ATE496025 T1 AT E496025T1 AT 06765662 T AT06765662 T AT 06765662T AT 06765662 T AT06765662 T AT 06765662T AT E496025 T1 ATE496025 T1 AT E496025T1
- Authority
- AT
- Austria
- Prior art keywords
- magnesium salts
- hmg
- coa reductase
- reductase inhibitors
- compositions
- Prior art date
Links
- 159000000003 magnesium salts Chemical class 0.000 title abstract 2
- 229940121710 HMGCoA reductase inhibitor Drugs 0.000 title 1
- 239000002471 hydroxymethylglutaryl coenzyme A reductase inhibitor Substances 0.000 title 1
- 229940096701 plain lipid modifying drug hmg coa reductase inhibitors Drugs 0.000 title 1
- XUKUURHRXDUEBC-KAYWLYCHSA-N Atorvastatin Chemical class C=1C=CC=CC=1C1=C(C=2C=CC(F)=CC=2)N(CC[C@@H](O)C[C@@H](O)CC(O)=O)C(C(C)C)=C1C(=O)NC1=CC=CC=C1 XUKUURHRXDUEBC-KAYWLYCHSA-N 0.000 abstract 1
- XUKUURHRXDUEBC-UHFFFAOYSA-N Atorvastatin Natural products C=1C=CC=CC=1C1=C(C=2C=CC(F)=CC=2)N(CCC(O)CC(O)CC(O)=O)C(C(C)C)=C1C(=O)NC1=CC=CC=C1 XUKUURHRXDUEBC-UHFFFAOYSA-N 0.000 abstract 1
- 208000035150 Hypercholesterolemia Diseases 0.000 abstract 1
- 241000124008 Mammalia Species 0.000 abstract 1
- 229960005370 atorvastatin Drugs 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN1108DE2005 | 2005-05-03 | ||
| PCT/IB2006/051396 WO2006117761A2 (en) | 2005-05-03 | 2006-05-03 | Magnesium salts of hmg-coa reductase inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE496025T1 true ATE496025T1 (de) | 2011-02-15 |
Family
ID=37308379
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT06765662T ATE496025T1 (de) | 2005-05-03 | 2006-05-03 | Magnesiumsalze von hmg-coa-reduktase-hemmern |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20100222405A1 (de) |
| EP (2) | EP2172452A1 (de) |
| AT (1) | ATE496025T1 (de) |
| DE (1) | DE602006019710D1 (de) |
| DK (1) | DK1879862T3 (de) |
| ES (1) | ES2304911T3 (de) |
| NO (1) | NO20076191L (de) |
| PT (1) | PT1879862E (de) |
| WO (1) | WO2006117761A2 (de) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE466840T1 (de) | 2005-11-21 | 2010-05-15 | Warner Lambert Co | Neue formen von är-(r*,r*)ü-2-(4-fluorphenyl)-b,d-dihydroxy-5-( -methylethyl)-3-phenyl-4- ä(phenylamino)carbonylü-1h-pyrrol-1-heptansäure magnesium |
| EP1963263A4 (de) * | 2005-11-29 | 2009-09-02 | Biocon Ltd | Polymorphe von [r-(r*,r*)]-2-(4-fluorphenyl)-beta, delta-dihydroxy-5-(l-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1h-pyrrol-1-heptansäure-magnesiumsalz (2:1) |
| WO2007099552A2 (en) * | 2006-03-02 | 2007-09-07 | Matrix Labaratories Ltd | Novel crystalline form of atovastatin hemi-magnesium |
| SI22255A (sl) * | 2006-04-14 | 2007-10-31 | Krka, Tovarna Zdravil, D.D., Novo Mesto | Novi polimorfi statinovih soli in njihova uporabav farmacevtskih formulacijah |
| IS8587A (is) * | 2006-12-27 | 2008-06-28 | Actavis Group Hf. | Atorvastatin lyfjasamsetning |
| WO2009063476A1 (en) * | 2007-11-16 | 2009-05-22 | Biocon Limited | A crystalline form of atorvastatin hemi magnesium salt and a process thereof |
| EP2130819A3 (de) | 2008-04-10 | 2009-12-23 | Ranbaxy Laboratories Limited | Kristalline Formen von Atorvastatin-Magnesium |
| WO2009157005A1 (en) * | 2008-06-26 | 2009-12-30 | Biocon Limited | Crystalline forms of atorvastatin hemi-magnesium salt and a process thereof |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FI94339C (fi) * | 1989-07-21 | 1995-08-25 | Warner Lambert Co | Menetelmä farmaseuttisesti käyttökelpoisen /R-(R*,R*)/-2-(4-fluorifenyyli)- , -dihydroksi-5-(1-metyylietyyli)-3-fenyyli-4-/(fenyyliamino)karbonyyli/-1H-pyrroli-1-heptaanihapon ja sen farmaseuttisesti hyväksyttävien suolojen valmistamiseksi |
| JP2004501191A (ja) * | 2000-06-28 | 2004-01-15 | テバ ファーマシューティカル インダストリーズ リミティド | カルベジロール |
| BR0307720A (pt) * | 2002-02-14 | 2005-01-25 | Ranbaxi Lab Ltd | Formulações de atorvastatina estabilizadas com adições de metal alcalino, método para produzir uma formulação farmacêutica e estabilizar dita formulação |
| EP1814541A4 (de) * | 2004-11-22 | 2009-10-28 | Dexcel Pharma Technologies Ltd | Stabile atorvastatin-formulierungen |
| US20080305158A1 (en) * | 2004-12-28 | 2008-12-11 | Ranbaxy Laboratories Limited | Methods For the Preparation of Stable Pharmaceutical Solid Dosage Forms of Atorvastatin and Amlodipine |
| EP1853249A2 (de) * | 2005-02-10 | 2007-11-14 | LifeCycle Pharma A/S | Stabile pharmazeutische zusammensetzung aus einer fixdosen-kombination von fenofibrat und einem hmg-coa-reductase-hemmer |
| ATE466840T1 (de) * | 2005-11-21 | 2010-05-15 | Warner Lambert Co | Neue formen von är-(r*,r*)ü-2-(4-fluorphenyl)-b,d-dihydroxy-5-( -methylethyl)-3-phenyl-4- ä(phenylamino)carbonylü-1h-pyrrol-1-heptansäure magnesium |
| EP1963263A4 (de) * | 2005-11-29 | 2009-09-02 | Biocon Ltd | Polymorphe von [r-(r*,r*)]-2-(4-fluorphenyl)-beta, delta-dihydroxy-5-(l-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1h-pyrrol-1-heptansäure-magnesiumsalz (2:1) |
| WO2007099552A2 (en) * | 2006-03-02 | 2007-09-07 | Matrix Labaratories Ltd | Novel crystalline form of atovastatin hemi-magnesium |
| SI22255A (sl) * | 2006-04-14 | 2007-10-31 | Krka, Tovarna Zdravil, D.D., Novo Mesto | Novi polimorfi statinovih soli in njihova uporabav farmacevtskih formulacijah |
| EP2016048A4 (de) * | 2006-05-11 | 2010-06-23 | Biocon Ltd | Kristalline form b4 von atorvastatin-magnesium und verfahren dafür |
| EP2130819A3 (de) * | 2008-04-10 | 2009-12-23 | Ranbaxy Laboratories Limited | Kristalline Formen von Atorvastatin-Magnesium |
-
2006
- 2006-05-03 PT PT06765662T patent/PT1879862E/pt unknown
- 2006-05-03 AT AT06765662T patent/ATE496025T1/de active
- 2006-05-03 ES ES06765662T patent/ES2304911T3/es active Active
- 2006-05-03 WO PCT/IB2006/051396 patent/WO2006117761A2/en not_active Ceased
- 2006-05-03 DE DE602006019710T patent/DE602006019710D1/de active Active
- 2006-05-03 EP EP08161846A patent/EP2172452A1/de not_active Withdrawn
- 2006-05-03 EP EP06765662A patent/EP1879862B1/de not_active Revoked
- 2006-05-03 US US11/913,582 patent/US20100222405A1/en not_active Abandoned
- 2006-05-03 DK DK06765662.9T patent/DK1879862T3/da active
-
2007
- 2007-11-30 NO NO20076191A patent/NO20076191L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| EP2172452A1 (de) | 2010-04-07 |
| EP1879862A2 (de) | 2008-01-23 |
| ES2304911T3 (es) | 2011-05-30 |
| DK1879862T3 (da) | 2011-05-16 |
| US20100222405A1 (en) | 2010-09-02 |
| WO2006117761A3 (en) | 2007-03-29 |
| PT1879862E (pt) | 2011-04-19 |
| NO20076191L (no) | 2008-01-30 |
| EP1879862B1 (de) | 2011-01-19 |
| DE602006019710D1 (de) | 2011-03-03 |
| WO2006117761A2 (en) | 2006-11-09 |
| ES2304911T1 (es) | 2008-11-01 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE602006010243D1 (de) | 4-(Phenylamino)-6-oxo-1,6-dihydropyridazine-3-carboxamid Derivate als MEK Inhibitoren zur Behandlung von hyperproliferativen Erkrankungen | |
| WO2012002741A3 (en) | Process for the preparation of hmg-coa reductase inhibitors and intermediates thereof | |
| EA201100311A1 (ru) | Амидные производные гетероарилов и их применение в качестве активаторов глюкокиназы | |
| WO2007079199A3 (en) | Substituted bis-amide metalloprotease inhibitors | |
| EA200702048A1 (ru) | Фармакокинетически улучшенные соединения | |
| EP1756106A4 (de) | Cyclohexylalaninderivate als dipeptidylpeptidase-iv-inhibitoren zur behandlung oder prävention von diabetes | |
| WO2007138282A3 (en) | Bi-aryl or aryl-heteroaryl substituted indoles | |
| WO2007097931A3 (en) | Aminotetrahydropyrans as dipeptidyl peptidase-iv inhibitors for the treatment or prevention of diabetes | |
| WO2007070434A3 (en) | Fused aminopiperidines as dipeptidyl peptidase-4 inhibitors for the treatment or prevention of diabetes | |
| WO2007015866A3 (en) | Inhibitors of p38 kinase and methods of treating inflammatory disorders | |
| TW200720272A (en) | Novel ortho-terphenyl inhibitors of p38 kinase and methods of treating inflammatory disorders | |
| MX2009003981A (es) | Agentes moduladores del receptor de calcio. | |
| SG166829A1 (en) | Process for (3r, 5r)-7-[2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4- [(4-hydroxy methyl phenyl amino) carbonyl]-pyrrol-1-yl]-3, 5-dihydroxy-heptanoic acid hemi calcium salt | |
| PT1742642E (pt) | Análogos de fosfonato de compostos inibidores da integrase do hiv | |
| WO2007079214A3 (en) | Prokineticin 2 receptor antagonists | |
| WO2007015877A3 (en) | Inhibitors of p38 kinase and methods of treating inflammatory disorders | |
| DK2363130T3 (da) | Kombination af HMG-CoA reduktaseinhibitorer atorvastatin eller simvastatin med en phosphodiesterase 4-inhibitor, såsom roflumilast til behandlingen af inflammatorisk pulmonære sygdomme | |
| NO20043919L (no) | Fremgangsmate for fremstilling av HMG-COA reduktaseinhiberende mevalonsyrederivater | |
| NO20076191L (no) | Magnesiumsalter av HMG-COA reduktaseinhibitorer | |
| WO2007137098A3 (en) | Sulfonyl-substituted bicyclic compounds as modulators of ppar | |
| TNSN05306A1 (en) | Substituted pyrrole derivatives. | |
| ATE444299T1 (de) | Neue boronatester | |
| EA200601678A1 (ru) | Новые имидазолы | |
| WO2008010087A3 (en) | Polymorphic forms of an hmg-coa reductase inhibitor and uses thereof | |
| EA201170822A1 (ru) | Стереоселективный синтез производных пиперидина |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 1879862 Country of ref document: EP |