ATE496035T1 - Stickstoffenthaltende heterocyclische verbindungen - Google Patents
Stickstoffenthaltende heterocyclische verbindungenInfo
- Publication number
- ATE496035T1 ATE496035T1 AT99912061T AT99912061T ATE496035T1 AT E496035 T1 ATE496035 T1 AT E496035T1 AT 99912061 T AT99912061 T AT 99912061T AT 99912061 T AT99912061 T AT 99912061T AT E496035 T1 ATE496035 T1 AT E496035T1
- Authority
- AT
- Austria
- Prior art keywords
- atom
- substituted
- represent
- nitrogen
- unsubstituted
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
- C07D239/94—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
- C07D473/32—Nitrogen atom
- C07D473/34—Nitrogen atom attached in position 6, e.g. adenine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Pyridine Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP8751498 | 1998-03-31 | ||
| PCT/JP1999/001665 WO1999051582A1 (en) | 1998-03-31 | 1999-03-31 | Nitrogenous heterocyclic compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE496035T1 true ATE496035T1 (de) | 2011-02-15 |
Family
ID=13917109
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99912061T ATE496035T1 (de) | 1998-03-31 | 1999-03-31 | Stickstoffenthaltende heterocyclische verbindungen |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US6423716B1 (de) |
| EP (1) | EP1067123B1 (de) |
| AT (1) | ATE496035T1 (de) |
| AU (1) | AU3053999A (de) |
| CA (1) | CA2326324C (de) |
| DE (1) | DE69943144D1 (de) |
| ES (1) | ES2356886T3 (de) |
| WO (1) | WO1999051582A1 (de) |
Families Citing this family (78)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU5261001A (en) * | 2000-04-27 | 2001-11-12 | Imperial Cancer Research Technology Ltd | Condensed heteroaryl derivatives |
| US6608053B2 (en) | 2000-04-27 | 2003-08-19 | Yamanouchi Pharmaceutical Co., Ltd. | Fused heteroaryl derivatives |
| IL153884A0 (en) | 2000-07-20 | 2003-07-31 | Neurogen Corp | Capsaicin receptor ligands |
| HU228668B1 (hu) * | 2000-08-18 | 2013-05-28 | Millennium Pharmaceuticals | Kináz inhibitor kinazolin-származékok és az ezeket tartalmazó gyógyszerkészítmények |
| EP1309568B1 (de) | 2000-08-18 | 2011-02-16 | Millennium Pharmaceuticals, Inc. | (Chinazolin-4-yl)piperazin-4-yl]thiocarboxamide als Hemmer der Phosphorylierung eines PDGF-Rezeptors |
| DE60143204D1 (de) * | 2000-08-18 | 2010-11-18 | Kyowa Hakko Kirin Co Ltd | N-aryl-ä4-Ä7-(alkoxy)Chinazolin-4-ylÜPiperazinylüCarboxamid-Verbindungen als PDGF-Rezeptoren Hemmer |
| DE60144284D1 (de) | 2000-11-01 | 2011-05-05 | Millennium Pharm Inc | Stickstoffhaltige heterozyklische verbindungen und verfahren zu deren herstellung |
| US20040259881A1 (en) * | 2001-02-02 | 2004-12-23 | Anjali Pandey | Nitrogenous heterocyclic compounds |
| WO2002072578A2 (en) | 2001-03-08 | 2002-09-19 | Millennium Pharmaceuticals | (homo) piperazine substituted quinolines for inhibiting the phosphorylation of kinases |
| AU2002242996A1 (en) * | 2001-03-29 | 2002-10-15 | Tanabe Seiyaku Co., Ltd. | Spiroisoquinoline compounds, methods for their preparation and intermediates |
| CN101100472A (zh) * | 2001-04-30 | 2008-01-09 | 美国拜尔公司 | 4-氨基-5,6-取代的噻吩并[2,3-d]嘧啶化合物及其应用 |
| EP1575916B1 (de) | 2001-08-31 | 2013-05-22 | The Rockefeller University | Phosphodiesteraseaktivität und regulation der durch phosphodiesterase-1-b vermittelten signalvermittlung im hirn |
| US6845657B2 (en) * | 2002-03-28 | 2005-01-25 | Harrison R. Cooper Systems, Inc. | Apparatus for sampling drill hole cuttings |
| DE60318875T2 (de) | 2002-06-28 | 2009-01-15 | Euro-Celtique S.A. | Therapeutische piperazin-derivate für die behandlung von schmerzen |
| US7262194B2 (en) * | 2002-07-26 | 2007-08-28 | Euro-Celtique S.A. | Therapeutic agents useful for treating pain |
| US7157462B2 (en) | 2002-09-24 | 2007-01-02 | Euro-Celtique S.A. | Therapeutic agents useful for treating pain |
| US7488823B2 (en) | 2003-11-10 | 2009-02-10 | Array Biopharma, Inc. | Cyanoguanidines and cyanoamidines as ErbB2 and EGFR inhibitors |
| NZ540092A (en) * | 2002-11-20 | 2007-06-29 | Array Biopharma Inc | Cyanoguanidines and cyanoamidines as ErbB2 and EGFR inhibitors |
| AU2004293026B2 (en) * | 2003-11-21 | 2012-01-19 | Array Biopharma Inc. | AKT protein kinase inhibitors |
| AU2005322085B2 (en) * | 2004-12-28 | 2012-07-19 | Exelixis, Inc. | [1H-pyrazolo[3, 4-d]pyrimidin-4-yl]-piperidine or -piperazine compounds as serine-threonine kinase modulators (p70S6K, Atk1 and Atk2) for the treatment of immunological, inflammatory and proliferative diseases |
| FR2880540B1 (fr) * | 2005-01-13 | 2008-07-11 | Aventis Pharma Sa | Utilisation de derives de la purine comme inhibiteurs de la proteine hsp90 |
| WO2006133261A2 (en) | 2005-06-06 | 2006-12-14 | Intra-Cellular Therapies, Inc. | Organic compounds |
| EP1919287A4 (de) * | 2005-08-23 | 2010-04-28 | Intra Cellular Therapies Inc | Organische verbindungen zur behandlung einer verringerten dopamin-rezeptorsignalisierungs-aktivität |
| AU2007217474A1 (en) * | 2006-02-21 | 2007-08-30 | Amgen Inc. | Cinnoline derivatives as phosphodiesterase 10 inhibitors |
| CA2644850A1 (en) * | 2006-03-08 | 2007-09-13 | Amgen Inc. | Quinoline and isoquinoline derivatives as phosphodiesterase 10 inhibitors |
| PL2041139T3 (pl) * | 2006-04-26 | 2012-05-31 | Hoffmann La Roche | Związki farmaceutyczne |
| KR20090021155A (ko) | 2006-04-26 | 2009-02-27 | 에프. 호프만-라 로슈 아게 | Ｐｉ3ｋ 억제제로서의 피리미딘 유도체 |
| US20080076924A1 (en) * | 2006-06-30 | 2008-03-27 | Patrick Betschmann | Piperazines as P2X7 antagonists |
| US8063050B2 (en) * | 2006-07-06 | 2011-11-22 | Array Biopharma Inc. | Hydroxylated and methoxylated pyrimidyl cyclopentanes as AKT protein kinase inhibitors |
| DE602007011628D1 (de) | 2006-07-06 | 2011-02-10 | Array Biopharma Inc | Dihydrofuropyrimidine als akt-proteinkinaseinhibitoren |
| RU2481336C2 (ru) | 2006-07-06 | 2013-05-10 | Эррэй Биофарма Инк. | Циклопента(d)пиримидины в качестве ингибиторов протеинкиназ акт |
| WO2008006039A1 (en) | 2006-07-06 | 2008-01-10 | Array Biopharma Inc. | Dihydrothieno pyrimidines as akt protein kinase inhibitors |
| WO2008063505A1 (en) * | 2006-11-13 | 2008-05-29 | Intra-Cellular Therapies, Inc. | Organic compounds |
| WO2008070095A1 (en) | 2006-12-05 | 2008-06-12 | Intra-Cellular Therapies, Inc. | Novel uses |
| EP2397477B1 (de) | 2007-01-16 | 2014-03-05 | Purdue Pharma LP | Heterocyclisch-substituierte Piperidinverbindungen und Verwendungen davon |
| US9409886B2 (en) | 2007-07-05 | 2016-08-09 | Array Biopharma Inc. | Pyrimidyl cyclopentanes as AKT protein kinase inhibitors |
| MX2009014013A (es) * | 2007-07-05 | 2010-01-28 | Array Biopharma Inc | Pirimidil ciclopentanos como inhibidores de la proteina cinasa akt. |
| US8846683B2 (en) | 2007-07-05 | 2014-09-30 | Array Biopharma, Inc. | Pyrimidyl cyclopentanes as Akt protein kinase inhibitors |
| CA2692502C (en) | 2007-07-05 | 2016-03-01 | Array Biopharma Inc. | Pyrimidyl cyclopentanes as akt protein kinase inhibitors |
| WO2009027820A2 (en) | 2007-08-31 | 2009-03-05 | Purdue Pharma L.P. | Substituted-quinoxaline-type-piperidine compounds and the uses thereof |
| GB0721095D0 (en) * | 2007-10-26 | 2007-12-05 | Piramed Ltd | Pharmaceutical compounds |
| US7946206B2 (en) * | 2007-11-21 | 2011-05-24 | Rocksmart, Llc | Quick-release system |
| ES2588238T3 (es) * | 2007-12-06 | 2016-10-31 | Intra-Cellular Therapies, Inc. | Derivados de pirazolopirimidin-4,6-diona y su uso como producto farmacéutico |
| WO2009089352A1 (en) | 2008-01-08 | 2009-07-16 | Array Biopharma Inc. | Pyrrolopyridines as kinase inhibitors |
| US8853216B2 (en) * | 2008-01-09 | 2014-10-07 | Array Biopharma, Inc. | Hydroxylated pyrimidyl cyclopentane as AKT protein kinase inhibitor |
| EP2242757B1 (de) | 2008-01-09 | 2012-08-01 | Array Biopharma, Inc. | Pyrazolopyridine als kinaseinhibitoren |
| US8835434B2 (en) * | 2008-01-09 | 2014-09-16 | Array Biopharma, Inc. | Hydroxylated pyrimidyl cyclopentanes as akt protein kinase inhibitors |
| RS52590B2 (sr) | 2008-07-21 | 2018-05-31 | Purdue Pharma Lp | Jedinjenja tipa supstituisanog hinoksalina sa premošćenim piperidinom i njihova upotreba |
| EP2370417A2 (de) * | 2008-11-21 | 2011-10-05 | Millennium Pharmaceuticals, Inc. | Lactatsalz von 4-[6-methoxy-7-(3-piperidin-1-yl-propoxy)chinazolin-4-yl]piperazin-1-carbonsäure-(4-isopropoxyphenyl)amid und pharmazeutische zusammensetzungen davon zur behandlung von krebs und anderen krankheiten bzw. störungen |
| MX2011005934A (es) | 2008-12-06 | 2011-12-16 | Intra Cellular Therapies Inc | Compuestos organicos. |
| BRPI0922700A2 (pt) | 2008-12-06 | 2015-08-11 | Intracellular Therapies Inc | Compostos orgânicos |
| AU2009322899A1 (en) | 2008-12-06 | 2010-06-10 | Intra-Cellular Therapies, Inc. | Organic compounds |
| WO2010098839A1 (en) | 2009-02-25 | 2010-09-02 | Intra-Cellular Therapies, Inc. | Pde 1 inhibitors for ophthalmic disorders |
| EP2434895A4 (de) | 2009-05-13 | 2013-08-07 | Intra Cellular Therapies Inc | Organische verbindungen |
| WO2011016861A2 (en) | 2009-08-05 | 2011-02-10 | Intra-Cellular Therapies, Inc. | Novel regulatory proteins and inhibitors |
| US9371327B2 (en) | 2010-05-31 | 2016-06-21 | Intra-Cellular Therapies, Inc. | PDE1 inhibitor compounds |
| EP2575817A4 (de) | 2010-05-31 | 2014-01-08 | Intra Cellular Therapies Inc | Organische verbindungen |
| EP2616469B1 (de) * | 2010-09-14 | 2016-10-26 | Exelixis, Inc. | 9h-purin-verbindungen als pi3k-delta-inhibitoren sowie verfahren zu deren herstellung |
| TR201815685T4 (tr) | 2011-04-01 | 2018-11-21 | Genentech Inc | Kanser tedavisi için akt ve mek inhibe edici bileşiklerin kombinasyonları. |
| FI2694072T4 (fi) | 2011-04-01 | 2024-09-30 | Genentech Inc | Akt-inhibiittoriyhdisteen ja abirateronin yhdistelmä käytettäväksi terapeuttisissa hoidoissa |
| RU2015102537A (ru) * | 2012-06-28 | 2016-08-20 | Эббви Инк. | Цианогуанидины и их применение в качестве противовирусных средств |
| WO2014086453A1 (en) * | 2012-12-07 | 2014-06-12 | Merck Patent Gmbh | Azaheterobicyclic compounds |
| EA027752B1 (ru) | 2012-12-20 | 2017-08-31 | Юсб Биофарма Спрл | Терапевтически активные производные пиразолопиримидина |
| USRE48622E1 (en) | 2012-12-20 | 2021-07-06 | UCB Biopharma SRL | Therapeutically active pyrazolo-pyrimidine derivatives |
| US9090618B2 (en) | 2012-12-27 | 2015-07-28 | Purdue Pharma L.P. | Substituted benzimidazole-type piperidine compounds and uses thereof |
| EP2956141A4 (de) | 2013-02-17 | 2016-10-26 | Intra Cellular Therapies Inc | Neuartige verwendungen |
| ES2717688T3 (es) | 2013-03-15 | 2019-06-24 | Intra Cellular Therapies Inc | Inhibidores de la PDE1 para uso en el tratamiento y/o prevención de lesiones de SNC, y enfermedades, trastornos o lesiones de SNP |
| DK2970279T3 (da) | 2013-03-15 | 2020-11-30 | Intra Cellular Therapies Inc | Organiske forbindelser |
| DK3157926T3 (da) | 2014-06-20 | 2019-08-19 | Intra Cellular Therapies Inc | Organiske forbindelser |
| US10131671B2 (en) | 2014-08-07 | 2018-11-20 | Intra-Cellular Therapies, Inc. | Organic compounds |
| US9546175B2 (en) | 2014-08-07 | 2017-01-17 | Intra-Cellular Therapies, Inc. | Organic compounds |
| US10285992B2 (en) | 2014-08-07 | 2019-05-14 | Intra-Cellular Therapies, Inc. | Combinations of PDE1 inhibitors and NEP inhibitors and associated methods |
| CA2961212C (en) | 2014-09-17 | 2024-02-06 | Intra-Cellular Therapies, Inc. | Compounds and methods |
| US10682354B2 (en) | 2016-03-28 | 2020-06-16 | Intra-Cellular Therapies, Inc. | Compositions and methods |
| US11291666B2 (en) | 2016-09-12 | 2022-04-05 | Intra-Cellular Therapies, Inc. | Uses |
| JP7401442B2 (ja) | 2018-01-31 | 2023-12-19 | イントラ－セルラー・セラピーズ・インコーポレイテッド | 新規使用 |
| US12410175B2 (en) | 2019-09-03 | 2025-09-09 | Intra-Cellular Therapies, Inc. | Compounds |
| US12364695B2 (en) | 2020-06-02 | 2025-07-22 | Intra-Cellular Therapies, Inc. | Methods of treating inflammatory disease |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NO128657B (de) * | 1966-10-31 | 1973-12-27 | Pfizer | |
| US3723434A (en) | 1970-07-17 | 1973-03-27 | Pfizer | Piperazino isoquinoline bronchodilators |
| SU474984A3 (ru) * | 1971-04-10 | 1975-06-25 | Д-Р Карл Томэ Гмбх (Фирма) | Способ получени пиридо (3,2- ) пиримидинов |
| JPS58172379A (ja) * | 1982-04-02 | 1983-10-11 | Showa Denko Kk | 新規なキナゾリン誘導体 |
| NZ225447A (en) | 1987-07-20 | 1991-12-23 | Merck & Co Inc | Piperazinyl derivatives of purine and purine isosteres and pharmaceutical compositions |
| DE69222637T2 (de) | 1991-05-10 | 1998-02-26 | Rhone Poulenc Rorer Int | Bis mono- und bicyclische aryl- und heteroarylderivate mit inhibierender wirkung auf die egf und/oder pdgf-rezeptor tyrosinkinase |
| NZ243082A (en) | 1991-06-28 | 1995-02-24 | Ici Plc | 4-anilino-quinazoline derivatives; pharmaceutical compositions, preparatory processes, and use thereof |
| US5521184A (en) | 1992-04-03 | 1996-05-28 | Ciba-Geigy Corporation | Pyrimidine derivatives and processes for the preparation thereof |
| JP3229693B2 (ja) | 1993-02-22 | 2001-11-19 | 協和醗酵工業株式会社 | ピペラジン誘導体 |
| US5656643A (en) | 1993-11-08 | 1997-08-12 | Rhone-Poulenc Rorer Pharmaceuticals Inc. | Bis mono-and bicyclic aryl and heteroaryl compounds which inhibit EGF and/or PDGF receptor tyrosine kinase |
| US5654307A (en) | 1994-01-25 | 1997-08-05 | Warner-Lambert Company | Bicyclic compounds capable of inhibiting tyrosine kinases of the epidermal growth factor receptor family |
| ES2109796T3 (es) | 1994-05-03 | 1998-01-16 | Ciba Geigy Ag | Derivados de pirrolopirimidilo con efecto antiproliferante. |
| GB9510757D0 (en) | 1994-09-19 | 1995-07-19 | Wellcome Found | Therapeuticaly active compounds |
| JP4249804B2 (ja) | 1995-04-03 | 2009-04-08 | ノバルティス・アクチエンゲゼルシャフト | ピラゾール誘導体およびその製造法 |
| CA2223081C (en) | 1995-06-07 | 2001-03-06 | Pfizer Inc. | Heterocyclic ring-fused pyrimidine derivatives |
| PL188959B1 (pl) | 1995-07-06 | 2005-05-31 | Novartis Ag | Pirolopirymidyny i sposoby ich wytwarzania |
| AR004010A1 (es) | 1995-10-11 | 1998-09-30 | Glaxo Group Ltd | Compuestos heterociclicos |
| DE69622183D1 (de) | 1995-11-07 | 2002-08-08 | Kirin Brewery | Chinolinderivate und chinazolinderivate welche die autophosphorylierung des von blutplättchen abstammenden wachstumsfaktorrezeptors inhibiren und sie enthaltende pharmazeutische zusammensetzungen |
| US6140317A (en) | 1996-01-23 | 2000-10-31 | Novartis Ag | Pyrrolopyrimidines and processes for their preparation |
| AU719392B2 (en) | 1996-10-01 | 2000-05-11 | Kyowa Hakko Kirin Co., Ltd. | Nitrogen-containing heterocyclic compounds |
-
1999
- 1999-03-31 DE DE69943144T patent/DE69943144D1/de not_active Expired - Lifetime
- 1999-03-31 ES ES99912061T patent/ES2356886T3/es not_active Expired - Lifetime
- 1999-03-31 CA CA2326324A patent/CA2326324C/en not_active Expired - Fee Related
- 1999-03-31 US US09/647,490 patent/US6423716B1/en not_active Expired - Lifetime
- 1999-03-31 WO PCT/JP1999/001665 patent/WO1999051582A1/ja not_active Ceased
- 1999-03-31 AT AT99912061T patent/ATE496035T1/de not_active IP Right Cessation
- 1999-03-31 EP EP99912061A patent/EP1067123B1/de not_active Expired - Lifetime
- 1999-03-31 AU AU30539/99A patent/AU3053999A/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP1067123A1 (de) | 2001-01-10 |
| WO1999051582A1 (en) | 1999-10-14 |
| EP1067123A4 (de) | 2002-04-03 |
| DE69943144D1 (de) | 2011-03-03 |
| EP1067123B1 (de) | 2011-01-19 |
| US6423716B1 (en) | 2002-07-23 |
| AU3053999A (en) | 1999-10-25 |
| CA2326324A1 (en) | 1999-10-14 |
| CA2326324C (en) | 2010-05-11 |
| ES2356886T3 (es) | 2011-04-14 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE69943144D1 (de) | Stickstoffenthaltende heterocyclische verbindungen | |
| FI953968A0 (fi) | Antraniiliset happojohdannaiset | |
| ATE480521T1 (de) | Stickstoff enthaltende heterocyclische verbindungen | |
| AU2001230564A1 (en) | Nitrogen-containing compounds having kinase inhibitory activity and drugs containing the same | |
| ATE368655T1 (de) | Stickstoffhaltige heterocyclische verbindung und arzneimittel davon | |
| CR7727A (es) | Compuestos quimicos | |
| ATE206412T1 (de) | Heterocyclische verbindungen als bradykinin antagonisten | |
| ATE452880T1 (de) | 2-aminonicotinamid-derivate und ihre verwendung als vegf-rezeptor tyrosin-kinase inhibitoren | |
| DK0976748T3 (da) | Pyrrolidinderivater med phospholispase A2-hæmmende aktivitet | |
| GR3006247T3 (de) | ||
| PT865281E (pt) | Derivados de benzimidazole substituidos por naftilo como anticoagulantes | |
| DE69813605D1 (de) | Benzofuranderivate | |
| WO2002028853A1 (en) | Benzylamine compound, process for producing the same, and intermediate therefor | |
| CA2273303A1 (en) | Thienylsulfonylamino(thio)carbonyl compounds | |
| EP1122253A4 (de) | Quinalozinon-derivate | |
| BG100954A (bg) | Нови производни на хидроксамови киселини, фармацевтични състави на тяхна основа и метод за получаването им | |
| DE69915471D1 (de) | Analoga von distamycin-zimtsäurederivaten, verfahren zu ihrer herstellung und ihre verwendung als antitumormittel | |
| IL136510A (en) | Acylated hetero-alicyclic derivatives and pharmaceutical compositions containing the same | |
| NO20053302D0 (no) | Imidazolderivater med affinitet for alfa 2-reseptoraktivitet. | |
| DE60239324D1 (de) | Phenyl- und pyridyl-piperidine mit tnf-wirkung | |
| TR199901102T2 (xx) | Bisiklik amin t�revleri. | |
| TH20779A (th) | สารประกอบฆ่าเห็ดรา |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |