ATE496064T1 - Lösliche formulierungen, die monomeres insulin und acyliertes insulin enthalten - Google Patents

Lösliche formulierungen, die monomeres insulin und acyliertes insulin enthalten

Info

Publication number
ATE496064T1
ATE496064T1 AT03722301T AT03722301T ATE496064T1 AT E496064 T1 ATE496064 T1 AT E496064T1 AT 03722301 T AT03722301 T AT 03722301T AT 03722301 T AT03722301 T AT 03722301T AT E496064 T1 ATE496064 T1 AT E496064T1
Authority
AT
Austria
Prior art keywords
insulin
formulations containing
containing monomeric
acylated
soluble formulations
Prior art date
Application number
AT03722301T
Other languages
English (en)
Inventor
Liselotte Langkjaer
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Application granted granted Critical
Publication of ATE496064T1 publication Critical patent/ATE496064T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/28—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Diabetes (AREA)
  • Veterinary Medicine (AREA)
  • Endocrinology (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
AT03722301T 2002-05-07 2003-05-02 Lösliche formulierungen, die monomeres insulin und acyliertes insulin enthalten ATE496064T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA200200683 2002-05-07
PCT/DK2003/000288 WO2003094956A1 (en) 2002-05-07 2003-05-02 Soluble formulations comprising monomeric insulin and acylated insulin

Publications (1)

Publication Number Publication Date
ATE496064T1 true ATE496064T1 (de) 2011-02-15

Family

ID=29414624

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03722301T ATE496064T1 (de) 2002-05-07 2003-05-02 Lösliche formulierungen, die monomeres insulin und acyliertes insulin enthalten

Country Status (8)

Country Link
US (2) US20040006000A1 (de)
EP (1) EP1506230B1 (de)
JP (2) JP5599543B2 (de)
AT (1) ATE496064T1 (de)
AU (1) AU2003236201A1 (de)
DE (1) DE60335797D1 (de)
ES (1) ES2360182T3 (de)
WO (1) WO2003094956A1 (de)

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JP5552046B2 (ja) * 2007-06-13 2014-07-16 ノボ・ノルデイスク・エー／エス インスリン誘導体を含有する薬学的製剤
WO2009063072A2 (en) 2007-11-16 2009-05-22 Novo Nordisk A/S Pharmaceutical compositions containing insulin and an insulinotropic peptide
JP5762001B2 (ja) 2008-03-14 2015-08-12 ノボ・ノルデイスク・エー／エス プロテアーゼ安定化インスリンアナログ
WO2009115469A1 (en) 2008-03-18 2009-09-24 Novo Nordisk A/S Protease stabilized, acylated insulin analogues
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JP2016519127A (ja) 2013-04-30 2016-06-30 ノヴォ ノルディスク アー／エス 新規投与レジメン
AU2014333979B2 (en) 2013-10-07 2018-02-15 Novo Nordisk A/S Novel derivative of an insulin analogue
CN112957455A (zh) 2014-01-09 2021-06-15 赛诺菲 胰岛素类似物和/或胰岛素衍生物的稳定化药物制剂
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JP7173953B2 (ja) * 2014-01-09 2022-11-16 サノフイ インスリンアナログおよび／またはインスリン誘導体の安定化された医薬製剤
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TWI748945B (zh) 2015-03-13 2021-12-11 德商賽諾菲阿凡提斯德意志有限公司 第２型糖尿病病患治療
TW201705975A (zh) 2015-03-18 2017-02-16 賽諾菲阿凡提斯德意志有限公司 第２型糖尿病病患之治療
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JO3749B1 (ar) 2015-08-27 2021-01-31 Lilly Co Eli تركيبات إنسولين سريعة المفعول
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WO2019125879A2 (en) 2017-12-18 2019-06-27 Merck Sharp & Dohme Corp. Conjugate based systems for controlled insulin delivery
EP3727424A4 (de) 2017-12-18 2021-10-27 Merck Sharp & Dohme Corp. Konjugatbasierte systeme für kontrollierte insulinfreisetzung
US10335464B1 (en) 2018-06-26 2019-07-02 Novo Nordisk A/S Device for titrating basal insulin
EP3853200B1 (de) 2018-09-18 2024-01-24 Eli Lilly and Company Erbumine salz von treprostinil
US12343383B2 (en) 2019-07-12 2025-07-01 Novo Nordisk A/S High concentration insulin formulation
AU2020351154A1 (en) * 2019-09-17 2022-03-31 Cass Pharmaceuticals, Inc. Subcutaneously injectable insulin formulations and methods of administration
CA3173417A1 (en) 2020-03-31 2021-10-07 Alborz Mahdavi Conjugates for selective responsiveness to vicinal diols
PH12023500012A1 (en) 2020-11-19 2024-03-11 Protomer Tech Inc Aromatic boron-containing compounds and insulin analogs
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Also Published As

Publication number Publication date
US20050261168A1 (en) 2005-11-24
WO2003094956A1 (en) 2003-11-20
EP1506230A1 (de) 2005-02-16
US7387996B2 (en) 2008-06-17
EP1506230B1 (de) 2011-01-19
JP2006511441A (ja) 2006-04-06
US20040006000A1 (en) 2004-01-08
JP2012233003A (ja) 2012-11-29
DE60335797D1 (de) 2011-03-03
ES2360182T3 (es) 2011-06-01
JP5599543B2 (ja) 2014-10-01
AU2003236201A1 (en) 2003-11-11

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties