ATE496070T1 - Poröse harzkügelchen und verfahren zur herstellung von nukleinsäure damit - Google Patents

Poröse harzkügelchen und verfahren zur herstellung von nukleinsäure damit

Info

Publication number
ATE496070T1
ATE496070T1 AT09163589T AT09163589T ATE496070T1 AT E496070 T1 ATE496070 T1 AT E496070T1 AT 09163589 T AT09163589 T AT 09163589T AT 09163589 T AT09163589 T AT 09163589T AT E496070 T1 ATE496070 T1 AT E496070T1
Authority
AT
Austria
Prior art keywords
porous resin
resin beads
nucleic acid
producing nucleic
acid therefrom
Prior art date
Application number
AT09163589T
Other languages
English (en)
Inventor
Kenjiro Mori
Eri Maeta
Tatsuya Konishi
Original Assignee
Nitto Denko Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nitto Denko Corp filed Critical Nitto Denko Corp
Application granted granted Critical
Publication of ATE496070T1 publication Critical patent/ATE496070T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00—Chemical modification by after-treatment
    • C08F8/12—Hydrolysis
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F12/00—Homopolymers and copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by an aromatic carbocyclic ring
    • C08F12/02—Monomers containing only one unsaturated aliphatic radical
    • C08F12/04—Monomers containing only one unsaturated aliphatic radical containing one ring
    • C08F12/14—Monomers containing only one unsaturated aliphatic radical containing one ring substituted by hetero atoms or groups containing heteroatoms
    • C08F12/22—Oxygen
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F12/00—Homopolymers and copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by an aromatic carbocyclic ring
    • C08F12/02—Monomers containing only one unsaturated aliphatic radical
    • C08F12/04—Monomers containing only one unsaturated aliphatic radical containing one ring
    • C08F12/14—Monomers containing only one unsaturated aliphatic radical containing one ring substituted by hetero atoms or groups containing heteroatoms
    • C08F12/22—Oxygen
    • C08F12/24—Phenols or alcohols
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F212/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by an aromatic carbocyclic ring
    • C08F212/02—Monomers containing only one unsaturated aliphatic radical
    • C08F212/04—Monomers containing only one unsaturated aliphatic radical containing one ring
    • C08F212/06—Hydrocarbons
    • C08F212/08—Styrene
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F212/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by an aromatic carbocyclic ring
    • C08F212/02—Monomers containing only one unsaturated aliphatic radical
    • C08F212/04—Monomers containing only one unsaturated aliphatic radical containing one ring
    • C08F212/14—Monomers containing only one unsaturated aliphatic radical containing one ring substituted by heteroatoms or groups containing heteroatoms
    • C08F212/22—Oxygen
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F212/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by an aromatic carbocyclic ring
    • C08F212/02—Monomers containing only one unsaturated aliphatic radical
    • C08F212/04—Monomers containing only one unsaturated aliphatic radical containing one ring
    • C08F212/14—Monomers containing only one unsaturated aliphatic radical containing one ring substituted by heteroatoms or groups containing heteroatoms
    • C08F212/22—Oxygen
    • C08F212/24—Phenols or alcohols
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F2800/00—Copolymer characterised by the proportions of the comonomers expressed
    • C08F2800/10—Copolymer characterised by the proportions of the comonomers expressed as molar percentages

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Emergency Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Saccharide Compounds (AREA)
  • Manufacture Of Porous Articles, And Recovery And Treatment Of Waste Products (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
AT09163589T 2008-06-25 2009-06-24 Poröse harzkügelchen und verfahren zur herstellung von nukleinsäure damit ATE496070T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2008165379A JP5276367B2 (ja) 2008-06-25 2008-06-25 多孔質樹脂ビーズおよびそれを用いる核酸の製造方法

Publications (1)

Publication Number Publication Date
ATE496070T1 true ATE496070T1 (de) 2011-02-15

Family

ID=41021060

Family Applications (1)

Application Number Title Priority Date Filing Date
AT09163589T ATE496070T1 (de) 2008-06-25 2009-06-24 Poröse harzkügelchen und verfahren zur herstellung von nukleinsäure damit

Country Status (6)

Country Link
US (1) US8592542B2 (de)
EP (1) EP2138519B1 (de)
JP (1) JP5276367B2 (de)
CN (1) CN101613430B (de)
AT (1) ATE496070T1 (de)
DE (1) DE602009000613D1 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5479828B2 (ja) * 2009-09-17 2014-04-23 日東電工株式会社 多孔質樹脂ビーズおよびそれを用いる核酸の製造方法
EP2666794A1 (de) 2012-05-23 2013-11-27 Nitto Denko Corporation Festphasenträger für Oligonukleotidsynthese und Oligonukleotidsyntheseverfahren
US20150152234A1 (en) * 2013-12-04 2015-06-04 Nitto Denko Corporation Porous resin bead and production method of nucleic acid by using same
CN106008841B (zh) * 2015-03-25 2020-03-31 株式会社Jsp 复合树脂颗粒及其制造方法
CN108728431B (zh) * 2018-04-24 2021-06-04 厦门纽克泰生物技术有限公司 核酸合成固相载体、制备方法及含有该载体的核酸合成装置、核酸合成方法
JP7510919B2 (ja) 2019-03-29 2024-07-04 住友化学株式会社 無機多孔質担体及びこれを用いた核酸の製造方法
CN114539458B (zh) * 2020-11-26 2023-07-25 西安蓝晓科技新材料股份有限公司 一种应用于固相合成的多孔树脂及其制备方法
US20240052116A1 (en) * 2022-07-29 2024-02-15 Dioxycle Electrolysis using membrane with acrylamide moiety
US11891468B1 (en) * 2022-07-29 2024-02-06 Dioxycle Polymers and membranes with acrylamide moiety
CN115403703B (zh) * 2022-09-29 2024-05-03 辽宁凯莱英医药化学有限公司 固定化4,5-二氰基咪唑、其制备方法及应用
WO2025095132A1 (ja) * 2023-11-02 2025-05-08 日東電工株式会社 多孔質樹脂ビーズおよびその製造方法ならびに該多孔質樹脂ビーズを用いた核酸の製造方法
US12421274B1 (en) 2024-10-03 2025-09-23 Agilent Technologies, Inc. Polymer beads for oligonucleotide synthesis

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5817481B2 (ja) * 1975-05-01 1983-04-07 旭化成株式会社 多孔性樹脂の製造法
US4458066A (en) 1980-02-29 1984-07-03 University Patents, Inc. Process for preparing polynucleotides
US5047524A (en) * 1988-12-21 1991-09-10 Applied Biosystems, Inc. Automated system for polynucleotide synthesis and purification
US5262530A (en) 1988-12-21 1993-11-16 Applied Biosystems, Inc. Automated system for polynucleotide synthesis and purification
JPH046463A (ja) * 1990-04-16 1992-01-10 W R Grace & Co 液体クロマトグラフィー用担体およびそれを用いた液体クロマトグラフィー法
JP3058561B2 (ja) * 1994-06-10 2000-07-04 大日精化工業株式会社 多孔質材料及びその製造方法
GB9814876D0 (en) * 1998-07-10 1998-09-09 Zeneca Ltd Polymer
US6335438B1 (en) * 1999-03-22 2002-01-01 Geir Fonnum Method for the manufacture of amino group containing support matrices, support matrices prepared by the method, and use of the support matrices
US6815020B2 (en) * 2001-08-31 2004-11-09 Eastman Kodak Company Ink jet recording element
GB0209539D0 (en) * 2002-04-26 2002-06-05 Avecia Ltd Monomer Polymer and process
DK1510541T3 (da) * 2003-08-29 2007-04-02 Nitto Denko Corp Poröse harpikspartikler og fremgangsmåde til fremstilling af disse
JP4799831B2 (ja) * 2004-05-14 2011-10-26 日東電工株式会社 多孔質樹脂の製造方法
JP4970881B2 (ja) 2006-09-21 2012-07-11 日東電工株式会社 固相合成用担体

Also Published As

Publication number Publication date
EP2138519B1 (de) 2011-01-19
EP2138519A1 (de) 2009-12-30
CN101613430B (zh) 2016-03-16
JP2010006888A (ja) 2010-01-14
US20090326210A1 (en) 2009-12-31
US8592542B2 (en) 2013-11-26
DE602009000613D1 (de) 2011-03-03
CN101613430A (zh) 2009-12-30
JP5276367B2 (ja) 2013-08-28

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