ATE496130T1 - Verfahren zur identifizierung von modulatoren eines g-protein-gekoppelten rezeptors - Google Patents

Verfahren zur identifizierung von modulatoren eines g-protein-gekoppelten rezeptors

Info

Publication number
ATE496130T1
ATE496130T1 AT04818967T AT04818967T ATE496130T1 AT E496130 T1 ATE496130 T1 AT E496130T1 AT 04818967 T AT04818967 T AT 04818967T AT 04818967 T AT04818967 T AT 04818967T AT E496130 T1 ATE496130 T1 AT E496130T1
Authority
AT
Austria
Prior art keywords
protein
dna
coupled receptor
function
identifying
Prior art date
Application number
AT04818967T
Other languages
English (en)
Inventor
Osamu Ohara
Takahiro Nagase
Michio Ohishi
Daisuke Okajima
Hiroshi Yokota
Original Assignee
Daiichi Sankyo Co Ltd
Kazusa Dna Res Inst Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daiichi Sankyo Co Ltd, Kazusa Dna Res Inst Foundation filed Critical Daiichi Sankyo Co Ltd
Application granted granted Critical
Publication of ATE496130T1 publication Critical patent/ATE496130T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • G01N33/76—Human chorionic gonadotropin including luteinising hormone, follicle stimulating hormone, thyroid stimulating hormone or their receptors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/72—Assays involving receptors, cell surface antigens or cell surface determinants for hormones
    • G01N2333/726—G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Obesity (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Psychiatry (AREA)
  • Pathology (AREA)
  • Reproductive Health (AREA)
  • Emergency Medicine (AREA)
  • Biotechnology (AREA)
  • Hospice & Palliative Care (AREA)
  • Child & Adolescent Psychology (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
AT04818967T 2003-11-19 2004-11-19 Verfahren zur identifizierung von modulatoren eines g-protein-gekoppelten rezeptors ATE496130T1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP2003389624 2003-11-19
JP2004130371 2004-04-26
JP2004304780 2004-10-19
PCT/JP2004/017239 WO2005049833A1 (ja) 2003-11-19 2004-11-19 G蛋白質共役型受容体をコードする遺伝子およびその遺伝子産物

Publications (1)

Publication Number Publication Date
ATE496130T1 true ATE496130T1 (de) 2011-02-15

Family

ID=34623571

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04818967T ATE496130T1 (de) 2003-11-19 2004-11-19 Verfahren zur identifizierung von modulatoren eines g-protein-gekoppelten rezeptors

Country Status (6)

Country Link
EP (1) EP1693456B1 (de)
JP (1) JP4638354B2 (de)
AT (1) ATE496130T1 (de)
DE (1) DE602004031148D1 (de)
DK (1) DK1693456T3 (de)
WO (1) WO2005049833A1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7527937B2 (en) 2003-11-19 2009-05-05 Daiichi Sankyo Company, Limited Assay employing a g-protein coupled receptor that is activated by CCK-8S
JPWO2006118289A1 (ja) * 2005-05-02 2008-12-18 第一三共株式会社 抗うつ作用を有する化合物の同定方法
JPWO2008053962A1 (ja) * 2006-11-02 2010-02-25 第一三共株式会社 抗不安作用を有する化合物の同定方法
JP4691571B2 (ja) 2008-03-04 2011-06-01 株式会社マルハニチロ食品 摂食調節剤
JP2010235492A (ja) * 2009-03-31 2010-10-21 Sekisui Chem Co Ltd シャペロニン−目的タンパク質複合体及びその製造方法
US10364350B2 (en) 2009-04-20 2019-07-30 Agency For Science, Technology And Research Vesicular system and uses thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4001976B2 (ja) * 1997-05-23 2007-10-31 オンコセラピー・サイエンス株式会社 ヒトｂａｉ遺伝子及びその利用
WO2002061087A2 (en) * 2000-12-19 2002-08-08 Lifespan Biosciences, Inc. Antigenic peptides, such as for g protein-coupled receptors (gpcrs), antibodies thereto, and systems for identifying such antigenic peptides
JP2003284573A (ja) * 2001-06-18 2003-10-07 National Institute Of Advanced Industrial & Technology グアノシン三リン酸結合タンパク質共役型の受容体
US20030143668A1 (en) * 2001-06-18 2003-07-31 National Institute Of Advanced Industrial Guanosine triphosphate-binding protein coupled receptors

Also Published As

Publication number Publication date
WO2005049833A1 (ja) 2005-06-02
EP1693456B1 (de) 2011-01-19
DK1693456T3 (da) 2011-03-21
JPWO2005049833A1 (ja) 2007-06-07
JP4638354B2 (ja) 2011-02-23
EP1693456A4 (de) 2007-07-11
EP1693456A1 (de) 2006-08-23
DE602004031148D1 (de) 2011-03-03

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