ATE500269T1 - Verbindungen mit wachstumshormon-freisetzenden eigenschaften - Google Patents

Verbindungen mit wachstumshormon-freisetzenden eigenschaften

Info

Publication number
ATE500269T1
ATE500269T1 AT99929114T AT99929114T ATE500269T1 AT E500269 T1 ATE500269 T1 AT E500269T1 AT 99929114 T AT99929114 T AT 99929114T AT 99929114 T AT99929114 T AT 99929114T AT E500269 T1 ATE500269 T1 AT E500269T1
Authority
AT
Austria
Prior art keywords
growth hormone
compounds
hormone releasing
releasing properties
properties
Prior art date
Application number
AT99929114T
Other languages
English (en)
Inventor
Bernd Peschke
Stefan Richter
Thomas Hansen
Michael Ankersen
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Application granted granted Critical
Publication of ATE500269T1 publication Critical patent/ATE500269T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0207Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-(X)4-C(=0), e.g. 'isosters', replacing two amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/02Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/02Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
    • A61P5/04Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin for decreasing, blocking or antagonising the activity of the hypothalamic hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/06Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Endocrinology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Hydrogenated Pyridines (AREA)
  • Peptides Or Proteins (AREA)
AT99929114T 1998-06-30 1999-06-29 Verbindungen mit wachstumshormon-freisetzenden eigenschaften ATE500269T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DKPA199800857 1998-06-30
DKPA199801440 1998-11-09
PCT/DK1999/000368 WO2000001726A1 (en) 1998-06-30 1999-06-29 Compounds with growth hormone releasing properties

Publications (1)

Publication Number Publication Date
ATE500269T1 true ATE500269T1 (de) 2011-03-15

Family

ID=26064788

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99929114T ATE500269T1 (de) 1998-06-30 1999-06-29 Verbindungen mit wachstumshormon-freisetzenden eigenschaften

Country Status (20)

Country Link
EP (1) EP1100824B1 (de)
JP (1) JP4511040B2 (de)
KR (1) KR100907638B1 (de)
CN (1) CN1304424C (de)
AT (1) ATE500269T1 (de)
AU (1) AU771644B2 (de)
BR (1) BRPI9911756B1 (de)
CA (1) CA2334315C (de)
CY (1) CY1111509T1 (de)
CZ (1) CZ299648B6 (de)
DE (1) DE69943239D1 (de)
DK (1) DK1100824T3 (de)
HU (1) HUP0102460A3 (de)
IL (1) IL140044A0 (de)
NO (1) NO331351B1 (de)
PL (1) PL199853B1 (de)
PT (1) PT1100824E (de)
RU (1) RU2298547C2 (de)
TW (1) TW593337B (de)
WO (1) WO2000001726A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2002331064B2 (en) * 2001-08-10 2007-08-23 Palatin Technologies, Inc. Peptidomimetics of biologically active metallopeptides
US7476653B2 (en) 2003-06-18 2009-01-13 Tranzyme Pharma, Inc. Macrocyclic modulators of the ghrelin receptor
KR20070010151A (ko) * 2004-03-30 2007-01-22 사파이어 세라퓨틱스, 인크. 성장 호르몬 분비촉진제를 이용하여 c-반응성 단백질을감소시키는 방법
ES2388501T3 (es) * 2004-08-12 2012-10-16 Helsinn Healthcare S.A. Uso de secretagogos de la hormona de crecimiento para estimular la motilidad del sistema gastrointestinal
JP4954983B2 (ja) * 2005-05-18 2012-06-20 ファーマサイエンス・インコーポレイテッド Birドメイン結合化合物
WO2007048224A1 (en) 2005-10-25 2007-05-03 Aegera Therapeutics Inc. Iap bir domain binding compounds
CU23558A1 (es) 2006-02-28 2010-07-20 Ct Ingenieria Genetica Biotech Compuestos análogos a los secretagogos peptidicos de la hormona de crecimiento
CN101657436A (zh) 2007-02-09 2010-02-24 特兰齐姆制药公司 大环生长素释放肽受体调节剂及其使用方法
CN107382827B (zh) * 2017-04-14 2021-01-01 江苏普莱医药生物技术有限公司 氨基酸衍生物或其药学上可接受的盐及应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3924506A1 (de) * 1989-07-25 1991-01-31 Hoechst Ag Renin-hemmende aminooligohydroxy-derivate
WO1994013696A1 (en) * 1992-12-11 1994-06-23 Merck & Co., Inc. Spiro piperidines and homologs which promote release of growth hormone
AU711104B2 (en) * 1995-06-22 1999-10-07 Novo Nordisk A/S Compounds with growth hormone releasing properties
CZ195098A3 (cs) * 1995-12-22 1998-10-14 Novo Nordisk A/S Sloučeniny uvolňující růstový hormon
US5922770A (en) * 1996-07-22 1999-07-13 Novo Nordisk A/S Compounds with growth hormone releasing properties
EP1005484A1 (de) * 1997-06-20 2000-06-07 Novo Nordisk A/S Verbindungen mit wachstumshormon freisetzenden eigenschaften

Also Published As

Publication number Publication date
KR100907638B1 (ko) 2009-07-14
AU771644B2 (en) 2004-04-01
DK1100824T3 (da) 2011-06-20
BR9911756A (pt) 2001-04-03
NO331351B1 (no) 2011-12-05
CZ20004565A3 (en) 2001-06-13
CZ299648B6 (cs) 2008-10-01
PT1100824E (pt) 2011-06-16
AU4603899A (en) 2000-01-24
PL199853B1 (pl) 2008-11-28
WO2000001726A1 (en) 2000-01-13
NO20006699L (no) 2001-02-28
TW593337B (en) 2004-06-21
DE69943239D1 (de) 2011-04-14
KR20010053310A (ko) 2001-06-25
NO20006699D0 (no) 2000-12-29
IL140044A0 (en) 2002-02-10
EP1100824A1 (de) 2001-05-23
EP1100824B1 (de) 2011-03-02
HUP0102460A2 (hu) 2001-11-28
CA2334315C (en) 2011-07-26
BRPI9911756B1 (pt) 2016-06-14
CN1304424C (zh) 2007-03-14
JP2002519436A (ja) 2002-07-02
CN1307588A (zh) 2001-08-08
HUP0102460A3 (en) 2001-12-28
JP4511040B2 (ja) 2010-07-28
RU2298547C2 (ru) 2007-05-10
CA2334315A1 (en) 2000-01-13
PL345204A1 (en) 2001-12-03
CY1111509T1 (el) 2015-08-05

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