ATE502119T1 - Verfahren zur bewertung pathologischer krankheitszustände unter verwendung extrazellulärer rna - Google Patents
Verfahren zur bewertung pathologischer krankheitszustände unter verwendung extrazellulärer rnaInfo
- Publication number
- ATE502119T1 ATE502119T1 AT02763327T AT02763327T ATE502119T1 AT E502119 T1 ATE502119 T1 AT E502119T1 AT 02763327 T AT02763327 T AT 02763327T AT 02763327 T AT02763327 T AT 02763327T AT E502119 T1 ATE502119 T1 AT E502119T1
- Authority
- AT
- Austria
- Prior art keywords
- evaluation
- disease conditions
- extracellular rna
- pathological disease
- neoplastic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Analytical Chemistry (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US30805401P | 2001-07-25 | 2001-07-25 | |
| PCT/US2002/023373 WO2003009806A2 (en) | 2001-07-25 | 2002-07-23 | Methods for evaluating pathologic conditions using extracellular rna |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE502119T1 true ATE502119T1 (de) | 2011-04-15 |
Family
ID=23192340
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02763327T ATE502119T1 (de) | 2001-07-25 | 2002-07-23 | Verfahren zur bewertung pathologischer krankheitszustände unter verwendung extrazellulärer rna |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US20030087276A1 (de) |
| EP (1) | EP1421215B1 (de) |
| AT (1) | ATE502119T1 (de) |
| AU (1) | AU2002327308A1 (de) |
| CA (1) | CA2455731C (de) |
| DE (1) | DE60239470D1 (de) |
| DK (1) | DK1421215T3 (de) |
| ES (1) | ES2367280T3 (de) |
| WO (1) | WO2003009806A2 (de) |
Families Citing this family (73)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2250118C (en) * | 1996-03-26 | 2009-09-29 | Michael S. Kopreski | Method enabling use of extracellular rna extracted from plasma or serum to detect, monitor or evaluate cancer |
| US7785842B2 (en) * | 1996-03-26 | 2010-08-31 | Oncomedx, Inc. | Comparative analysis of extracellular RNA species |
| US8043835B1 (en) | 1996-03-26 | 2011-10-25 | Oncomedx, Inc. | Methods for detecting and monitoring cancer using extracellular RNA |
| US20080261292A1 (en) * | 1998-09-22 | 2008-10-23 | Oncomedx, Inc. | Method Enabling the Use of Extracellular Ribonucleic Acid (RNA) Extracted from Plasma or Serum to Detect, Monitor or Evaluate Cancer or Premalignant Conditions |
| US20100159464A1 (en) * | 2001-11-05 | 2010-06-24 | Oncomedx, Inc. | Method for Detection of DNA Methyltransferase RNA in Plasma and Serum |
| US7022478B2 (en) | 2002-05-14 | 2006-04-04 | The Chinese University Of Hong Kong | Methods for evaluating stroke or cardiac ischemia by nucleic acid detection |
| CA2445204C (en) | 2002-10-16 | 2014-08-12 | Streck Laboratories, Inc. | Method and device for collecting and preserving cells for analysis |
| KR20070004725A (ko) | 2004-02-20 | 2007-01-09 | 더 리전츠 오브 더 유니버시티 오브 캘리포니아 | 타액 mRNA 프로파일링, 생물 마커 및 관련 방법 및부품 키트 |
| US11111543B2 (en) | 2005-07-29 | 2021-09-07 | Natera, Inc. | System and method for cleaning noisy genetic data and determining chromosome copy number |
| US9424392B2 (en) | 2005-11-26 | 2016-08-23 | Natera, Inc. | System and method for cleaning noisy genetic data from target individuals using genetic data from genetically related individuals |
| US11111544B2 (en) | 2005-07-29 | 2021-09-07 | Natera, Inc. | System and method for cleaning noisy genetic data and determining chromosome copy number |
| US20090111733A1 (en) * | 2006-07-19 | 2009-04-30 | President And Fellows Of Harvard College | Par-4 related methods and compositions |
| WO2009114543A2 (en) * | 2008-03-11 | 2009-09-17 | Sequenom, Inc. | Nucleic acid-based tests for prenatal gender determination |
| US8252528B2 (en) * | 2008-06-12 | 2012-08-28 | The Invention Science Fund I, Llc | Methods, compositions, and kits for collecting and detecting oligonucleotides |
| US8614057B2 (en) * | 2008-06-12 | 2013-12-24 | The Invention Science Fund I, Llc | Methods for collecting and detecting oligonucleotides |
| US8252529B2 (en) * | 2008-06-12 | 2012-08-28 | The Invention Science Fund I, Llc | Methods for collecting and detecting oligonucleotides |
| US8962247B2 (en) * | 2008-09-16 | 2015-02-24 | Sequenom, Inc. | Processes and compositions for methylation-based enrichment of fetal nucleic acid from a maternal sample useful for non invasive prenatal diagnoses |
| US8476013B2 (en) | 2008-09-16 | 2013-07-02 | Sequenom, Inc. | Processes and compositions for methylation-based acid enrichment of fetal nucleic acid from a maternal sample useful for non-invasive prenatal diagnoses |
| US20100167271A1 (en) * | 2008-12-30 | 2010-07-01 | Streck, Inc. | Method for screening blood using a preservative that may be in a substantially solid state form |
| US11634747B2 (en) * | 2009-01-21 | 2023-04-25 | Streck Llc | Preservation of fetal nucleic acids in maternal plasma |
| US8304187B2 (en) | 2009-02-18 | 2012-11-06 | Streck, Inc. | Preservation of cell-free RNA in blood samples |
| US20110111410A1 (en) * | 2009-11-09 | 2011-05-12 | Streck, Inc. | Stabilization of rna in intact cells within a blood sample |
| DK2516680T3 (en) | 2009-12-22 | 2016-05-02 | Sequenom Inc | Method and kits to identify aneuploidy |
| US11939634B2 (en) | 2010-05-18 | 2024-03-26 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| US12545960B2 (en) | 2010-05-18 | 2026-02-10 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| US11332793B2 (en) | 2010-05-18 | 2022-05-17 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| US12655483B2 (en) | 2010-05-18 | 2026-06-16 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| US12152275B2 (en) | 2010-05-18 | 2024-11-26 | Natera, Inc. | Methods for non-invasive prenatal ploidy calling |
| US11326208B2 (en) | 2010-05-18 | 2022-05-10 | Natera, Inc. | Methods for nested PCR amplification of cell-free DNA |
| US20240158855A1 (en) | 2010-05-18 | 2024-05-16 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| US11332785B2 (en) | 2010-05-18 | 2022-05-17 | Natera, Inc. | Methods for non-invasive prenatal ploidy calling |
| EP2854058A3 (de) | 2010-05-18 | 2015-10-28 | Natera, Inc. | Verfahren zur nichtinvasiven pränatalen Ploidiezuordnung |
| US20190010543A1 (en) | 2010-05-18 | 2019-01-10 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| US11322224B2 (en) | 2010-05-18 | 2022-05-03 | Natera, Inc. | Methods for non-invasive prenatal ploidy calling |
| US9677118B2 (en) | 2014-04-21 | 2017-06-13 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| US12221653B2 (en) | 2010-05-18 | 2025-02-11 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| US10316362B2 (en) | 2010-05-18 | 2019-06-11 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| US11339429B2 (en) | 2010-05-18 | 2022-05-24 | Natera, Inc. | Methods for non-invasive prenatal ploidy calling |
| US11408031B2 (en) | 2010-05-18 | 2022-08-09 | Natera, Inc. | Methods for non-invasive prenatal paternity testing |
| AU2011348100B2 (en) | 2010-12-22 | 2016-08-25 | Natera, Inc. | Methods for non-invasive prenatal paternity testing |
| JP6153874B2 (ja) | 2011-02-09 | 2017-06-28 | ナテラ, インコーポレイテッド | 非侵襲的出生前倍数性呼び出しのための方法 |
| WO2012149339A2 (en) | 2011-04-29 | 2012-11-01 | Sequenom, Inc. | Quantification of a minority nucleic acid species |
| EP2704740B1 (de) | 2011-05-04 | 2016-10-05 | Streck, Inc. | Inaktiviertes schweinegrippe-virus und verfahren zu seiner herstellung |
| EP4155401A1 (de) | 2012-03-02 | 2023-03-29 | Sequenom, Inc. | Verfahren und prozesse zur nichtinvasiven beurteilung genetischer variationen |
| WO2013151664A1 (en) | 2012-04-02 | 2013-10-10 | modeRNA Therapeutics | Modified polynucleotides for the production of proteins |
| US9572897B2 (en) | 2012-04-02 | 2017-02-21 | Modernatx, Inc. | Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins |
| US9283287B2 (en) | 2012-04-02 | 2016-03-15 | Moderna Therapeutics, Inc. | Modified polynucleotides for the production of nuclear proteins |
| US10501513B2 (en) | 2012-04-02 | 2019-12-10 | Modernatx, Inc. | Modified polynucleotides for the production of oncology-related proteins and peptides |
| US10501512B2 (en) | 2012-04-02 | 2019-12-10 | Modernatx, Inc. | Modified polynucleotides |
| US9920361B2 (en) | 2012-05-21 | 2018-03-20 | Sequenom, Inc. | Methods and compositions for analyzing nucleic acid |
| US10504613B2 (en) | 2012-12-20 | 2019-12-10 | Sequenom, Inc. | Methods and processes for non-invasive assessment of genetic variations |
| US20140093873A1 (en) | 2012-07-13 | 2014-04-03 | Sequenom, Inc. | Processes and compositions for methylation-based enrichment of fetal nucleic acid from a maternal sample useful for non-invasive prenatal diagnoses |
| US20140100126A1 (en) | 2012-08-17 | 2014-04-10 | Natera, Inc. | Method for Non-Invasive Prenatal Testing Using Parental Mosaicism Data |
| EP3597774A1 (de) | 2013-03-13 | 2020-01-22 | Sequenom, Inc. | Primer zur analyse der dna-methylierung |
| EP3024323B1 (de) | 2013-07-24 | 2022-10-19 | Streck, Inc. | Zusammensetzungen und verfahren zur stabilisierung zirkulierender tumorzellen |
| WO2015138774A1 (en) | 2014-03-13 | 2015-09-17 | Sequenom, Inc. | Methods and processes for non-invasive assessment of genetic variations |
| US12492429B2 (en) | 2014-04-21 | 2025-12-09 | Natera, Inc. | Detecting mutations and ploidy in chromosomal segments |
| RU2717641C2 (ru) | 2014-04-21 | 2020-03-24 | Натера, Инк. | Обнаружение мутаций и плоидности в хромосомных сегментах |
| US20180173845A1 (en) | 2014-06-05 | 2018-06-21 | Natera, Inc. | Systems and Methods for Detection of Aneuploidy |
| US11168351B2 (en) | 2015-03-05 | 2021-11-09 | Streck, Inc. | Stabilization of nucleic acids in urine |
| EP4428863A3 (de) | 2015-05-11 | 2024-12-11 | Natera, Inc. | Verfahren und zusammensetzungen zur bestimmung der ploidie |
| US20170145475A1 (en) | 2015-11-20 | 2017-05-25 | Streck, Inc. | Single spin process for blood plasma separation and plasma composition including preservative |
| JP7280044B2 (ja) | 2016-04-15 | 2023-05-23 | ナテラ, インコーポレイテッド | 肺癌の検出方法 |
| EP3491381B1 (de) | 2016-07-29 | 2025-09-24 | Streck LLC | Suspensionszusammensetzung zur kontrolle einer hämatologischen analyse |
| WO2018067517A1 (en) | 2016-10-04 | 2018-04-12 | Natera, Inc. | Methods for characterizing copy number variation using proximity-litigation sequencing |
| GB201618485D0 (en) | 2016-11-02 | 2016-12-14 | Ucl Business Plc | Method of detecting tumour recurrence |
| US10011870B2 (en) | 2016-12-07 | 2018-07-03 | Natera, Inc. | Compositions and methods for identifying nucleic acid molecules |
| JP7293244B2 (ja) | 2017-10-19 | 2023-06-19 | ストレック, インコーポレイテッド | 溶血、凝固調節および細胞外小胞の安定化のための組成物 |
| WO2019118926A1 (en) | 2017-12-14 | 2019-06-20 | Tai Diagnostics, Inc. | Assessing graft suitability for transplantation |
| EP3737773B1 (de) | 2018-01-12 | 2023-04-12 | Natera, Inc. | Neuartige primer und verwendungen davon |
| DK3781714T3 (da) | 2018-04-14 | 2026-03-30 | Natera Inc | Fremgangsmåder til cancerpåvisning og -overvågning ved personlig påvisning af cirkulerende tumor-dna |
| US12234509B2 (en) | 2018-07-03 | 2025-02-25 | Natera, Inc. | Methods for detection of donor-derived cell-free DNA |
| US12305235B2 (en) | 2019-06-06 | 2025-05-20 | Natera, Inc. | Methods for detecting immune cell DNA and monitoring immune system |
Family Cites Families (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4350156A (en) * | 1980-05-29 | 1982-09-21 | Japan Foundation For Artificial Organs | Method and apparatus for on-line filtration removal of macromolecules from a physiological fluid |
| DE3171592D1 (en) * | 1980-09-25 | 1985-09-05 | Terumo Corp | Plasma separator |
| EP0091539B2 (de) * | 1982-03-31 | 1996-11-27 | Ajinomoto Co., Inc. | Das Polypeptid Interleukin-2 kodierendes Gen, rekombinante, dieses Gen enthaltende DNA, diese rekombinante DNA aufweisende Zelllinien und Verfahren zur Herstellung von Interleukin-2 unter Verwendung der genannten Zellen |
| US4699877A (en) * | 1982-11-04 | 1987-10-13 | The Regents Of The University Of California | Methods and compositions for detecting human tumors |
| US4683195A (en) * | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
| US5274087A (en) * | 1986-08-13 | 1993-12-28 | Molecular Diagnostics, Inc. | cDNA coding for carcinoembryonic antigen (CEA) |
| US5532220A (en) * | 1987-08-31 | 1996-07-02 | The Regents Of The University Of California | Genetic mechanisms of tumor suppression |
| US5124246A (en) * | 1987-10-15 | 1992-06-23 | Chiron Corporation | Nucleic acid multimers and amplified nucleic acid hybridization assays using same |
| CA1340807C (en) * | 1988-02-24 | 1999-11-02 | Lawrence T. Malek | Nucleic acid amplification process |
| US4874858A (en) * | 1988-03-28 | 1989-10-17 | The B. F. Goodrich Company | Triazine-containing multisilane coupling agents for coating glass fibers, for adhesives, and for protective coatings |
| US4999290A (en) * | 1988-03-31 | 1991-03-12 | The Board Of Regents, The University Of Texas System | Detection of genomic abnormalities with unique aberrant gene transcripts |
| US4874853A (en) * | 1988-04-18 | 1989-10-17 | City Of Hope | Synthetic oligonucleotides useful in diagnosis of chronic myelogenous leukemia |
| US5098890A (en) * | 1988-11-07 | 1992-03-24 | Temple University-Of The Commonwealth System Of Higher Education | Antisence oligonucleotides to c-myb proto-oncogene and uses thereof |
| US5087617A (en) * | 1989-02-15 | 1992-02-11 | Board Of Regents, The University Of Texas System | Methods and compositions for treatment of cancer using oligonucleotides |
| US5217889A (en) * | 1990-10-19 | 1993-06-08 | Roninson Igor B | Methods and applications for efficient genetic suppressor elements |
| US5155018A (en) * | 1991-07-10 | 1992-10-13 | Hahnemann University | Process and kit for isolating and purifying RNA from biological sources |
| ATE197964T1 (de) * | 1991-10-04 | 2000-12-15 | Philadelphia Children Hospital | Bestimmung von mutationen im zusammenhang mit dem digeorge-syndrom |
| AU3729393A (en) * | 1992-02-20 | 1993-09-13 | State Of Oregon Acting By And Through The Oregon State Board Of Higher Education On Behalf Of Oregon State University, The | Boomerand DNA amplification |
| EP0667920B1 (de) * | 1992-10-29 | 2003-01-15 | Thomas Jefferson University | Methoden zur detektion von mikrometastasen bei prostata-krebs |
| US5429923A (en) * | 1992-12-11 | 1995-07-04 | President And Fellows Of Harvard College | Method for detecting hypertrophic cardiomyophathy associated mutations |
| US5300635A (en) * | 1993-02-01 | 1994-04-05 | University Of Iowa Research Foundation | Quaternary amine surfactants and methods of using same in isolation of nucleic acids |
| US6051374A (en) * | 1994-02-14 | 2000-04-18 | Abbott Laboratories | Non-A, non-B, non-C, non-D, non-E hepatitis reagents and methods for their use |
| DE69637552D1 (de) * | 1995-03-17 | 2008-07-10 | Wayne John Cancer Inst | Nachweis von Brustmetastasen unter Verwendung eines Mehrfachmarker-Tests |
| FR2737500B1 (fr) * | 1995-08-03 | 1997-08-29 | Bio Merieux | Materiel viral et fragments nucleotidiques associes a la sclerose en plaques, a des fins de diagnostic, prophylactiques et therapeutiques |
| US6759217B2 (en) * | 1996-03-26 | 2004-07-06 | Oncomedx, Inc. | Method enabling use of extracellular RNA extracted from plasma or serum to detect, monitor or evaluate cancer |
| US6794135B1 (en) * | 1996-03-26 | 2004-09-21 | Oncomedx, Inc. | Method for detection of 5T4 RNA in plasma or serum |
| US6607898B1 (en) * | 1996-03-26 | 2003-08-19 | Oncomedx, Inc. | Method for detection of hTR and hTERT telomerase-associated RNA in plasma or serum |
| CA2250118C (en) * | 1996-03-26 | 2009-09-29 | Michael S. Kopreski | Method enabling use of extracellular rna extracted from plasma or serum to detect, monitor or evaluate cancer |
| JP4044142B2 (ja) * | 1996-10-04 | 2008-02-06 | ビー. アーノビッツ,ハワード | 核酸の診断検出 |
| JP2002372533A (ja) * | 2001-06-13 | 2002-12-26 | Kiwamu Akagi | 血液の検査方法、検査用チップ、並びに検査装置 |
| CA2451483C (en) * | 2001-06-25 | 2011-02-15 | Oncomedx, Inc. | Methods for detecting and monitoring cox-2 rna in plasma and serum |
-
2002
- 2002-07-23 ES ES02763327T patent/ES2367280T3/es not_active Expired - Lifetime
- 2002-07-23 DE DE60239470T patent/DE60239470D1/de not_active Expired - Lifetime
- 2002-07-23 WO PCT/US2002/023373 patent/WO2003009806A2/en not_active Ceased
- 2002-07-23 CA CA2455731A patent/CA2455731C/en not_active Expired - Lifetime
- 2002-07-23 AU AU2002327308A patent/AU2002327308A1/en not_active Abandoned
- 2002-07-23 AT AT02763327T patent/ATE502119T1/de not_active IP Right Cessation
- 2002-07-23 DK DK02763327.0T patent/DK1421215T3/da active
- 2002-07-23 EP EP02763327A patent/EP1421215B1/de not_active Revoked
- 2002-07-23 US US10/201,382 patent/US20030087276A1/en not_active Abandoned
-
2007
- 2007-12-10 US US11/953,808 patent/US20080096217A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| CA2455731C (en) | 2012-02-07 |
| WO2003009806A2 (en) | 2003-02-06 |
| AU2002327308A1 (en) | 2003-02-17 |
| EP1421215A4 (de) | 2006-02-15 |
| CA2455731A1 (en) | 2003-02-06 |
| WO2003009806A3 (en) | 2003-10-16 |
| US20030087276A1 (en) | 2003-05-08 |
| EP1421215A2 (de) | 2004-05-26 |
| DE60239470D1 (de) | 2011-04-28 |
| DK1421215T3 (da) | 2011-06-27 |
| EP1421215B1 (de) | 2011-03-16 |
| US20080096217A1 (en) | 2008-04-24 |
| ES2367280T3 (es) | 2011-11-02 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE60239470D1 (de) | Verfahren zur bewertung pathologischer krankheitszustände unter verwendung extrazellulärer rna | |
| WO2004046729A3 (en) | Bodily fluid markers of tissue hypoxia | |
| ATE312946T1 (de) | Verfahren und vorrichtung zur bestimmung der gewebespezifität von freier dna in körperflüssigkeiten | |
| WO2007001342A3 (en) | Exhaled breath condensate collection and assay system and method | |
| DE602004024539D1 (de) | Verfahren und systeme zur diagnose von nicht das zentrale nervensystem (zns) betreffenden krankheiten in zns-proben | |
| DE60233949D1 (de) | Diagnostische marker für schlaganfall und hirntrauma sowie verfahren zur verwendung davon | |
| DE69938662D1 (de) | Spurendetektion von analyten mit hilfe artifizieller olfaktometrie | |
| CY1105322T1 (el) | Μεθοδοι και συνθεσεις για την ανιχνευση παθολογικων συμβαντων | |
| DE60318987D1 (de) | Verfahren zur diagnose von juvenilen idiopathischen skoliosen und verwandten erkrankungen | |
| ATE418072T1 (de) | Verfahren zur diagnose von gebärmutterhalskrebs | |
| DE60025170D1 (de) | Diagnostisches verfahren für asthma | |
| DE60038614D1 (de) | Verfahren zur diagnose von synovialen oder osteoartikulären erkrankungen | |
| ATE436017T1 (de) | Verfahren zur verwendung physiologischer marker für die abschätzung eines herz-kreislauf-risikos | |
| AU6679501A (en) | A method for detecting a lipoprotein-acute phase protein complex and predicting an increased risk of system failure or mortality | |
| WO2007015113A3 (en) | New protein isoforms of the pif-family and uses thereof | |
| DE602004027534D1 (de) | Diagnostische verfahren für therapeutische verbindungen sowie verfahren zur überwachung der azathioprin-therapie | |
| WO2002103059A3 (en) | Innate immunity markers for rapid diagnosis of infectious diseases | |
| FI990380A7 (fi) | Diagnostinen ja seulontamenetelmä | |
| ATE498020T1 (de) | 5t4 rna in plasma und serum als marker für neoplastische erkrankungen | |
| WO2003068958A1 (fr) | Procede d'analyse d'un acide nucleique specifiant un gene presentant une modification de son niveau d'expression liee a la schizophrenie | |
| CN105755146A (zh) | Serpinb3基因在制备骨关节炎诊断制剂中的应用 | |
| ATE485515T1 (de) | Verfahren zur diagnose einer person mit multipler sklerose | |
| ATE423321T1 (de) | Verfahren zur detektion von prpsc unter verwendung von gruppe ii aminoglykosid antibiotika | |
| ATE442456T1 (de) | Verfahren zur bestimmung von zirkulierender dns in plasma und zum nachweis von krebs | |
| WO2005060627A3 (en) | Methods of assessing the risk of non-traumatic bone fracture |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |