ATE50249T1 - Gegen mikroben und tumore wirkende phenazincarboxaldehyde und derivate. - Google Patents

Gegen mikroben und tumore wirkende phenazincarboxaldehyde und derivate.

Info

Publication number
ATE50249T1
ATE50249T1 AT86304420T AT86304420T ATE50249T1 AT E50249 T1 ATE50249 T1 AT E50249T1 AT 86304420 T AT86304420 T AT 86304420T AT 86304420 T AT86304420 T AT 86304420T AT E50249 T1 ATE50249 T1 AT E50249T1
Authority
AT
Austria
Prior art keywords
carbon atoms
hydroxyl
optionally substituted
alkyl
methyl
Prior art date
Application number
AT86304420T
Other languages
English (en)
Inventor
Christopher F Bigge
Edward F Elslager
James C French
Blanche D Graham
Gerard C Hokanson
Stephen W Mamber
Tim A Smitka
Josefino B Tunac
John H Wilton
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Application granted granted Critical
Publication of ATE50249T1 publication Critical patent/ATE50249T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
    • C07D241/38—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
    • C07D241/46—Phenazines
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/10—Nitrogen as only ring hetero atom
    • C12P17/12—Nitrogen as only ring hetero atom containing a six-membered hetero ring
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/465—Streptomyces
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/886—Streptomyces

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT86304420T 1985-06-10 1986-06-10 Gegen mikroben und tumore wirkende phenazincarboxaldehyde und derivate. ATE50249T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/743,321 US4657909A (en) 1985-06-10 1985-06-10 Antimicrobial and antitumor phenazine carboxaldehydes and derivatives
EP86304420A EP0205339B1 (de) 1985-06-10 1986-06-10 Gegen Mikroben und Tumore wirkende Phenazincarboxaldehyde und Derivate

Publications (1)

Publication Number Publication Date
ATE50249T1 true ATE50249T1 (de) 1990-02-15

Family

ID=24988349

Family Applications (1)

Application Number Title Priority Date Filing Date
AT86304420T ATE50249T1 (de) 1985-06-10 1986-06-10 Gegen mikroben und tumore wirkende phenazincarboxaldehyde und derivate.

Country Status (5)

Country Link
US (1) US4657909A (de)
EP (1) EP0205339B1 (de)
JP (1) JPS61286374A (de)
AT (1) ATE50249T1 (de)
DE (1) DE3668889D1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW226369B (de) * 1991-07-03 1994-07-11 Hoechst Ag
US5637591A (en) * 1995-06-02 1997-06-10 Fuji Immunopharmaceuticals Corp. Antimicrobial and anticollagenase activity of phenazine-5, 10-dioxide and derivatives
KR100441247B1 (ko) * 2001-07-31 2004-07-21 학교법인 이화학당 피리도페나진다이온 유도체, 그의 제조방법 및 이를함유하는 항암제
WO2006040650A1 (en) * 2004-10-12 2006-04-20 Glenmark Pharmaceuticals S.A. 4-methoxyacridine-1-carboxamide derivatives and the phenazine and oxanthrene analogs as pde4-inhibitors for the treatment of asthma and chronic pulmonary disease (copd)
JP2017500368A (ja) * 2013-12-24 2017-01-05 ユニバーシティー オブ フロリダ リサーチ ファンデーション， インク． 抗微生物剤としてのフェナジン誘導体
CN105801497B (zh) * 2016-04-13 2018-11-16 上海交通大学 一种天然吩嗪类化合物及其制备方法和用途

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3359165A (en) * 1966-11-02 1967-12-19 Upjohn Co Antibiotic lomondomycin and method of production
CH615425A5 (en) * 1975-04-21 1980-01-31 Sandoz Ag Process for the preparation of novel alkyl 6-substituted 9-methoxy-1-phenazinecarboxylates
CH615424A5 (en) * 1975-04-21 1980-01-31 Sandoz Ag Process for the preparation of novel 6-substituted 9-methoxy-1-phenazinecarboxylic acids and their alkyl esters
US4377579A (en) * 1981-12-03 1983-03-22 Minnesota Mining And Manufacturing Company N-(Tetrazol-5-yl)phenazine-1-carboxamides

Also Published As

Publication number Publication date
DE3668889D1 (de) 1990-03-15
EP0205339A1 (de) 1986-12-17
JPS61286374A (ja) 1986-12-16
US4657909A (en) 1987-04-14
EP0205339B1 (de) 1990-02-07

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee