ATE502647T1 - Zubereitungen enthaltend sincalide - Google Patents

Zubereitungen enthaltend sincalide

Info

Publication number: ATE502647T1
Authority: AT; Austria
Prior art keywords: sincalide; preparations containing; methods; formulations; sincalide formulations
Prior art date: 2002-08-16

Application number

AT03818433T

Other languages

English (en)

Inventor

Edmund Metcalfe

Jo Anna Monteferrante

Margaret Newborn

Irene Ropiak

Ernst Schramm

Gregory White

Jules Zodda

Original Assignee

Bracco Suisse Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-08-16

Filing date

2003-08-15

Publication date

2011-04-15

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=31714996&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE502647(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2003-08-15 Application filed by Bracco Suisse Sa filed Critical Bracco Suisse Sa

2011-04-15 Application granted granted Critical

2011-04-15 Publication of ATE502647T1 publication Critical patent/ATE502647T1/de

Links

108010087230 Sincalide Proteins 0.000 title abstract 5
IZTQOLKUZKXIRV-YRVFCXMDSA-N sincalide Chemical compound C([C@@H](C(=O)N[C@@H](CCSC)C(=O)NCC(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC=1C=CC=CC=1)C(N)=O)NC(=O)[C@@H](N)CC(O)=O)C1=CC=C(OS(O)(=O)=O)C=C1 IZTQOLKUZKXIRV-YRVFCXMDSA-N 0.000 title abstract 5
229960002959 sincalide Drugs 0.000 title abstract 5
238000002360 preparation method Methods 0.000 title 1
238000009472 formulation Methods 0.000 abstract 3
239000000203 mixture Substances 0.000 abstract 3
238000000034 method Methods 0.000 abstract 2
239000004067 bulking agent Substances 0.000 abstract 1
239000002738 chelating agent Substances 0.000 abstract 1
210000000232 gallbladder Anatomy 0.000 abstract 1
239000003381 stabilizer Substances 0.000 abstract 1
239000004094 surface-active agent Substances 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/2207—Gastrins; Cholecystokinins [CCK]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/186—Quaternary ammonium compounds, e.g. benzalkonium chloride or cetrimide
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/0002—General or multifunctional contrast agents, e.g. chelated agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0402—Organic compounds carboxylic acid carriers, fatty acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Oil, Petroleum & Natural Gas (AREA)
Gastroenterology & Hepatology (AREA)
Bioinformatics & Cheminformatics (AREA)
Immunology (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Zoology (AREA)
Endocrinology (AREA)
Dermatology (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Inorganic Chemistry (AREA)
Physics & Mathematics (AREA)
Optics & Photonics (AREA)
Medicinal Preparation (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

AT03818433T 2002-08-16 2003-08-15 Zubereitungen enthaltend sincalide ATE502647T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US10/222,540 US6803046B2 (en)	2002-08-16	2002-08-16	Sincalide formulations
PCT/IB2003/006513 WO2005027954A2 (en)	2002-08-16	2003-08-15	Sincalide formulations

Publications (1)

Publication Number	Publication Date
ATE502647T1 true ATE502647T1 (de)	2011-04-15

Family

ID=31714996

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT03818433T ATE502647T1 (de)	2002-08-16	2003-08-15	Zubereitungen enthaltend sincalide

Country Status (9)

Country	Link
US (13)	US6803046B2 (de)
EP (1)	EP1631305B1 (de)
JP (1)	JP4751993B2 (de)
CN (1)	CN100374154C (de)
AT (1)	ATE502647T1 (de)
AU (1)	AU2003304382B2 (de)
CA (1)	CA2503982C (de)
DE (1)	DE60336509D1 (de)
WO (1)	WO2005027954A2 (de)

Families Citing this family (22)

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WO2004007520A2 (en) *	2002-07-12	2004-01-22	Medarex, Inc.	Methods and compositions for preventing oxidative degradation of proteins
US6803046B2 (en) *	2002-08-16	2004-10-12	Bracco International B.V.	Sincalide formulations
US20050256097A1 (en) *	2004-05-11	2005-11-17	Kosan Biosciences, Inc.	Pharmaceutical solution formulations containing 17-AAG
US20070243264A1 (en) *	2006-04-18	2007-10-18	Aram Garabedian	Thickened Dilute Hypochlorite
US7923425B2 (en) *	2006-08-21	2011-04-12	Henkel Ag & Co. Kgaa	Low-foaming, acidic low-temperature cleaner and process for cleaning surfaces
BRPI0718374A2 (pt)	2006-09-29	2013-06-25	Johnson & Johnson Vision Care	mÉtodos e dispositivos oftÁlmicos usados no tratamento de alergias oculares
US20080098614A1 (en) *	2006-10-03	2008-05-01	Wyeth	Lyophilization methods and apparatuses
WO2008077712A1 (en) *	2006-12-22	2008-07-03	Sigma-Tau Industrie Farmaceutiche Riunite S.P.A.	Gel useful for the delivery of ophthalmic drugs
US8617568B2 (en)	2007-07-10	2013-12-31	Medy-Tox, Inc.	Pharmaceutical liquid composition of botulinum toxin with improved stability
US9801818B2 (en) *	2007-12-31	2017-10-31	Samyang Biopharmaceuticals Corporation	Method for stabilizing amphiphilic block copolymer micelle composition containing poorly water-soluble drug
EP2236520A1 (de) *	2009-03-31	2010-10-06	Leukocare Ag	Stabilisierungszusammensetzung für immobilisierte Biomoleküle
CN103027890B (zh) *	2011-09-29	2014-06-18	天津市汉康医药生物技术有限公司	供注射用的布洛芬药物组合物
HUE032392T2 (en)	2012-11-20	2017-09-28	Fresenius Kabi Usa Llc	Kaszpofunginacetát compositions
PL2926805T3 (pl)	2014-03-31	2016-12-30		Stałe kompozycje farmaceutyczne zawierające pochodne biopteryny oraz zastosowania takich kompozycji
CN104761645A (zh) *	2015-04-30	2015-07-08	山东禹王制药有限公司	α干扰素融合蛋白制剂及应用
JP6491747B2 (ja)	2015-09-30	2019-03-27	デューク・ユニヴァーシティ	磁気共鳴画像法用の造影剤
US20180360917A1 (en) *	2017-06-15	2018-12-20	Apicore Llc	Sincalide formulations and methods of use
US11110063B2 (en)	2017-08-25	2021-09-07	MAIA Pharmaceuticals, Inc.	Storage stable sincalide formulations
WO2019099965A1 (en) *	2017-11-20	2019-05-23	Just Biotherapeutics, Inc.	Aflibercept formulations containing a lysine salt as tonicifying agent and uses thereof
EP3863686A1 (de) *	2018-10-12	2021-08-18	Advanced Accelerator Applications International S.A.	Pharmazeutische zusammensetzung mit einem radiomarkierten gprp-antagonisten und einem tensid
WO2022071822A1 (en)	2020-09-29	2022-04-07	Limited Liability Company "Topcon Positioning Systems"	Maneuvering system for autonomous wheeled robot for optimally reaching starting point
JP2023119488A (ja) *	2022-02-16	2023-08-28	ニプロ株式会社	スガマデクス含有の液体製剤

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US3937819A (en) *	1974-07-22	1976-02-10	E. R. Squibb & Sons, Inc.	Method of stabilizing an injectable composition of a cholecystokinin active octapeptide
IT1204430B (it) *	1986-01-10	1989-03-01	Alfio Bertolini	Composizioni farmaceutiche comprendenti peptidi del gruppo colecistochinina-cerulina per il trattamento terapeutico degli stati di shock e dell'insufficienza respiratoria e cardiocircolatoria
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JPH03505334A (ja) *	1989-04-11	1991-11-21	イミユノバイオロジー・リサーチ・インスチチユート・インコーポレーテツド	凍結乾燥されたペプチド製剤
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DE19645250A1 (de)	1996-11-02	1998-05-07	Merck Patent Gmbh	Stabile wäßrige Formulierung von 3-(N-Butylacetamino)-propionsäureethylester
CH692322A5 (it)	1997-05-26	2002-05-15	Westy Ag	Formulazione iniettabile limpida di Propofol.
DE69928563T2 (de) *	1998-12-09	2006-07-27	Chiron Corp. (N.D.Ges.D. Staates Delaware), Emeryville	Abgeben von neurotropischen Wirkstoffen an das Zentralnervensystem
JP2000247903A (ja) *	1999-03-01	2000-09-12	Chugai Pharmaceut Co Ltd	長期安定化製剤
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US6440414B1 (en) *	1999-10-01	2002-08-27	Amgen Inc.	Pharmaceutical compositions of fibrinolytic agent
US6579521B2 (en) *	2000-10-20	2003-06-17	Chiron Corporation	Methods of therapy for HIV infection
US6803046B2 (en) *	2002-08-16	2004-10-12	Bracco International B.V.	Sincalide formulations

2002
- 2002-08-16 US US10/222,540 patent/US6803046B2/en not_active Expired - Lifetime
2003
- 2003-08-15 CA CA2503982A patent/CA2503982C/en not_active Expired - Lifetime
- 2003-08-15 CN CNB038241374A patent/CN100374154C/zh not_active Expired - Lifetime
- 2003-08-15 WO PCT/IB2003/006513 patent/WO2005027954A2/en not_active Ceased
- 2003-08-15 JP JP2005509018A patent/JP4751993B2/ja not_active Expired - Lifetime
- 2003-08-15 EP EP03818433A patent/EP1631305B1/de not_active Expired - Lifetime
- 2003-08-15 AU AU2003304382A patent/AU2003304382B2/en not_active Expired
- 2003-08-15 DE DE60336509T patent/DE60336509D1/de not_active Expired - Lifetime
- 2003-08-15 AT AT03818433T patent/ATE502647T1/de not_active IP Right Cessation
2004
- 2004-08-19 US US10/921,732 patent/US20050020502A1/en not_active Abandoned
2009
- 2009-10-28 US US12/607,337 patent/US20100047175A1/en not_active Abandoned
2011
- 2011-12-02 US US13/309,848 patent/US20120128581A1/en not_active Abandoned
2013
- 2013-10-28 US US14/064,379 patent/US20140065071A1/en not_active Abandoned
2014
- 2014-10-02 US US14/504,498 patent/US20150017097A1/en not_active Abandoned
2015
- 2015-04-27 US US14/696,658 patent/US20150224166A1/en not_active Abandoned
2016
- 2016-09-30 US US15/281,489 patent/US20170014470A1/en not_active Abandoned
2017
- 2017-05-05 US US15/587,471 patent/US20170281719A1/en not_active Abandoned
- 2017-11-08 US US15/807,555 patent/US20180064781A1/en not_active Abandoned
2019
- 2019-10-01 US US16/589,230 patent/US20200030406A1/en not_active Abandoned
2020
- 2020-04-27 US US16/858,815 patent/US20200254052A1/en not_active Abandoned
- 2020-10-01 US US17/060,191 patent/US20210093689A1/en not_active Abandoned

Also Published As

Publication number	Publication date
EP1631305B1 (de)	2011-03-23
JP4751993B2 (ja)	2011-08-17
US20200030406A1 (en)	2020-01-30
CA2503982A1 (en)	2005-03-31
AU2003304382B2 (en)	2008-11-06
EP1631305A2 (de)	2006-03-08
AU2003304382A1 (en)	2005-04-28
US20170014470A1 (en)	2017-01-19
US20150017097A1 (en)	2015-01-15
CN1756557A (zh)	2006-04-05
US20140065071A1 (en)	2014-03-06
CA2503982C (en)	2011-09-27
US20200254052A1 (en)	2020-08-13
US20180064781A1 (en)	2018-03-08
DE60336509D1 (de)	2011-05-05
US20100047175A1 (en)	2010-02-25
US20050020502A1 (en)	2005-01-27
US20170281719A1 (en)	2017-10-05
US20040033243A1 (en)	2004-02-19
CN100374154C (zh)	2008-03-12
US20150224166A1 (en)	2015-08-13
WO2005027954A3 (en)	2005-10-20
US20210093689A1 (en)	2021-04-01
WO2005027954A2 (en)	2005-03-31
JP2006515321A (ja)	2006-05-25
US6803046B2 (en)	2004-10-12
US20120128581A1 (en)	2012-05-24

Legal Events

Date	Code	Title	Description
2011-09-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
DE60336509D1 (de)	2011-05-05	Zubereitungen enthaltend sincalide
IS6950A (is)	2003-09-12	Samsetning epóþílonhliðstæðna og efnameðferðarlyfja til meðhöndlunar frumufjölgunarsjúkdóma
CY1111872T1 (el)	2015-11-04	Συνθεσεις υποτασικου λιπιδιου (προσταγλανδινης) και τιμολολης - σχετικες μεθοδοι χρησης
AU2002360488A8 (en)	2003-09-29	Methods and devices for detection and therapy of atheromatous plaque
ID26033A (id)	2000-11-16	Metode penstabilan komposisi bahan farmasi dengan penggunaan khusus dari antioksidan
DK1718677T3 (da)	2012-07-09	Monovalente antistoffragmenter egnede som terapeutiske midler
MXPA03011006A (es)	2004-02-27	Compuestos de cicloalquil urea benzo-fusionados 1,4-disustituidos.
BR0315157A (pt)	2005-08-09	Métodos de tratar doença de alzheimer empregando-se anticorpos direcionados contra peptìdeo beta amilóide e composições deste
NO20042964L (no)	2004-09-07	Spiroazasykliske forbindelser som monoaminreseptormodulatorer
EP1404356A4 (de)	2005-04-06	Cd10-aktivierte prodrug-verbindungen
TR200003036T2 (tr)	2001-01-22	12,13-Modifiye edilmiş epotilon türevleri
ATE433973T1 (de)	2009-07-15	Azolylaminoazine als inhibitoren von proteinkinasen
ATE556706T1 (de)	2012-05-15	Fettalkohol-arzneimittel-konjugate
WO2001044247A3 (en)	2002-01-03	Agents and methods for the treatment of proliferative diseases
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