ATE502956T1 - Modifizierte vegf und pdgf mit verbesserten angiogenen eigenschaften - Google Patents

Modifizierte vegf und pdgf mit verbesserten angiogenen eigenschaften

Info

Publication number
ATE502956T1
ATE502956T1 AT06789808T AT06789808T ATE502956T1 AT E502956 T1 ATE502956 T1 AT E502956T1 AT 06789808 T AT06789808 T AT 06789808T AT 06789808 T AT06789808 T AT 06789808T AT E502956 T1 ATE502956 T1 AT E502956T1
Authority
AT
Austria
Prior art keywords
pdgf
angiogenic properties
modified vegf
improved
improved angiogenic
Prior art date
Application number
AT06789808T
Other languages
English (en)
Inventor
Kari Alitalo
Tuomas Tammela
Salla Keskitalo
Katri Pajusola
Markku Jeltsch
Seppo Yla-Herttuala
Terhi Karpanen
Ulf Eriksson
Marko Uutela
Original Assignee
Vegenics Pty Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vegenics Pty Ltd filed Critical Vegenics Pty Ltd
Application granted granted Critical
Publication of ATE502956T1 publication Critical patent/ATE502956T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Amplifiers (AREA)
  • Signal Processing For Digital Recording And Reproducing (AREA)
AT06789808T 2005-08-15 2006-08-15 Modifizierte vegf und pdgf mit verbesserten angiogenen eigenschaften ATE502956T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US70822605P 2005-08-15 2005-08-15
PCT/US2006/032012 WO2007022287A2 (en) 2005-08-15 2006-08-15 Modified vegf and pdgf with improved angiogenic properties

Publications (1)

Publication Number Publication Date
ATE502956T1 true ATE502956T1 (de) 2011-04-15

Family

ID=37670985

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06789808T ATE502956T1 (de) 2005-08-15 2006-08-15 Modifizierte vegf und pdgf mit verbesserten angiogenen eigenschaften

Country Status (7)

Country Link
US (2) US8025886B2 (de)
EP (1) EP1919944B1 (de)
AT (1) ATE502956T1 (de)
AU (1) AU2006279462A1 (de)
DE (1) DE602006020881D1 (de)
ES (1) ES2363758T3 (de)
WO (1) WO2007022287A2 (de)

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CN101392026B (zh) * 2008-10-09 2011-11-09 黄岚 用于预防和治疗纤维化类疾病以及肝癌的多肽
AU2010236584A1 (en) * 2009-04-13 2011-11-10 Northwestern University Novel peptide-based scaffolds for cartilage regeneration and methods for their use
WO2011154308A1 (en) 2010-06-08 2011-12-15 Proyecto De Biomedicina Cima, S.L. New compositions and cell therapy methods for the treatment of cirrhosis
WO2012149515A2 (en) * 2011-04-29 2012-11-01 Northwestern University Novel vegf mimetic peptide-based scaffolds for therapeutic angiogenesis and methods for their use
US9663564B2 (en) 2013-03-15 2017-05-30 The Regents Of The University Of California Vectors and methods to treat ischemia
US20140065110A1 (en) * 2012-08-31 2014-03-06 The Regents Of The University Of California Genetically modified msc and therapeutic methods
EP3096769A1 (de) * 2014-01-21 2016-11-30 University of Helsinki Therapeutische verwendung von vegfr-3-liganden
EP3478718A4 (de) * 2016-07-01 2020-07-29 Paracrine Therapeutics AB Verfahren und zusammensetzungen zur hemmung von pdgf-cc
CN107828819B (zh) * 2017-10-30 2020-11-03 武汉生物工程学院 一种利用ANP或IgANP基因构建重组腺病毒的方法及重组腺病毒和应用
WO2019098385A1 (ja) * 2017-11-20 2019-05-23 コニカミノルタ株式会社 薬剤評価方法
CN108774286A (zh) * 2018-06-28 2018-11-09 浙江众意生物科技有限公司 一种vegf-a单克隆抗体及试剂盒
CA3144845A1 (en) * 2019-06-25 2020-12-30 In3Bio Ltd. Stabilized chimeric synthetic proteins and therapeutic uses thereof
WO2024002271A1 (en) * 2022-06-29 2024-01-04 Tianjin University Pdgf-d prodomain and its mutant and fusion

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Also Published As

Publication number Publication date
US20070142282A1 (en) 2007-06-21
US20120071406A1 (en) 2012-03-22
WO2007022287A3 (en) 2007-07-26
ES2363758T3 (es) 2011-08-16
WO2007022287A2 (en) 2007-02-22
DE602006020881D1 (de) 2011-05-05
EP1919944B1 (de) 2011-03-23
AU2006279462A1 (en) 2007-02-22
EP1919944A2 (de) 2008-05-14
US8025886B2 (en) 2011-09-27

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