ATE503744T1 - Nicht-nukleosidische reverse-transkriptase-hemmer - Google Patents

Nicht-nukleosidische reverse-transkriptase-hemmer

Info

Publication number
ATE503744T1
ATE503744T1 AT07802503T AT07802503T ATE503744T1 AT E503744 T1 ATE503744 T1 AT E503744T1 AT 07802503 T AT07802503 T AT 07802503T AT 07802503 T AT07802503 T AT 07802503T AT E503744 T1 ATE503744 T1 AT E503744T1
Authority
AT
Austria
Prior art keywords
reverse transcriptase
transcriptase inhibitors
nucleosidic reverse
nucleosidic
inhibitors
Prior art date
Application number
AT07802503T
Other languages
English (en)
Inventor
Joshua Kennedy-Smith
Wylie Solang Palmer
Zachary Kevin Sweeney
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Application granted granted Critical
Publication of ATE503744T1 publication Critical patent/ATE503744T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
    • C07D231/56—Benzopyrazoles; Hydrogenated benzopyrazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AT07802503T 2006-08-16 2007-08-06 Nicht-nukleosidische reverse-transkriptase-hemmer ATE503744T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US83827206P 2006-08-16 2006-08-16
PCT/EP2007/058116 WO2008019968A1 (en) 2006-08-16 2007-08-06 Non-nucleoside reverse transcriptase inhibitors

Publications (1)

Publication Number Publication Date
ATE503744T1 true ATE503744T1 (de) 2011-04-15

Family

ID=38663155

Family Applications (1)

Application Number Title Priority Date Filing Date
AT07802503T ATE503744T1 (de) 2006-08-16 2007-08-06 Nicht-nukleosidische reverse-transkriptase-hemmer

Country Status (23)

Country Link
US (2) US7713974B2 (de)
EP (1) EP2057125B1 (de)
JP (1) JP5216768B2 (de)
KR (1) KR101401811B1 (de)
CN (1) CN101501002B (de)
AR (1) AR062366A1 (de)
AT (1) ATE503744T1 (de)
AU (1) AU2007286345B2 (de)
BR (1) BRPI0715193A2 (de)
CA (1) CA2658984C (de)
CL (1) CL2007002346A1 (de)
DE (1) DE602007013573D1 (de)
DK (1) DK2057125T3 (de)
ES (1) ES2360893T3 (de)
IL (1) IL196655A (de)
MX (1) MX2009001198A (de)
NO (1) NO20090405L (de)
PE (1) PE20080734A1 (de)
PL (1) PL2057125T3 (de)
PT (1) PT2057125E (de)
RU (1) RU2451676C2 (de)
TW (1) TWI417293B (de)
WO (1) WO2008019968A1 (de)

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CN106614663A (zh) * 2016-12-29 2017-05-10 新沂市中诺新材料科技有限公司 一种新型纳米级吲唑类农药合成方法
CN113511960A (zh) * 2021-08-20 2021-10-19 郑州华赞医药科技有限公司 一种1-氯-3-甲氧基-5-甲基苯的合成方法

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Also Published As

Publication number Publication date
TW200817397A (en) 2008-04-16
CA2658984C (en) 2014-12-02
JP5216768B2 (ja) 2013-06-19
IL196655A (en) 2012-09-24
CA2658984A1 (en) 2008-02-21
NO20090405L (no) 2009-01-30
KR20090040438A (ko) 2009-04-24
CN101501002B (zh) 2012-06-27
IL196655A0 (en) 2009-11-18
US20080045511A1 (en) 2008-02-21
EP2057125A1 (de) 2009-05-13
US7713974B2 (en) 2010-05-11
TWI417293B (zh) 2013-12-01
JP2010500392A (ja) 2010-01-07
AU2007286345A1 (en) 2008-02-21
PT2057125E (pt) 2011-05-31
RU2009109354A (ru) 2010-09-27
WO2008019968A1 (en) 2008-02-21
US8063064B2 (en) 2011-11-22
ES2360893T3 (es) 2011-06-10
BRPI0715193A2 (pt) 2013-10-01
AU2007286345B2 (en) 2012-03-08
CN101501002A (zh) 2009-08-05
PL2057125T3 (pl) 2011-09-30
DE602007013573D1 (de) 2011-05-12
PE20080734A1 (es) 2008-06-14
AR062366A1 (es) 2008-11-05
EP2057125B1 (de) 2011-03-30
US20110059975A1 (en) 2011-03-10
KR101401811B1 (ko) 2014-05-29
MX2009001198A (es) 2009-02-11
RU2451676C2 (ru) 2012-05-27
CL2007002346A1 (es) 2008-03-14
DK2057125T3 (da) 2011-05-16

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