ATE505203T1 - Pharmazeutische kombination aus aliskiren und valsartan - Google Patents

Pharmazeutische kombination aus aliskiren und valsartan

Info

Publication number: ATE505203T1
Authority: AT; Austria
Prior art keywords: aliskiren; valsartan; minutes; dose combination; fixed dose
Prior art date: 2007-09-28

Application number

AT08835893T

Other languages

English (en)

Inventor

Catherine Curdy

Shoufeng Li

Dieter Becker

Burkhard Schluetermann

Frederic Gerber

Original Assignee

Novartis Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2007-09-28

Filing date

2008-09-24

Publication date

2011-04-15

2008-09-24 Application filed by Novartis Ag filed Critical Novartis Ag

2011-04-15 Application granted granted Critical

2011-04-15 Publication of ATE505203T1 publication Critical patent/ATE505203T1/de

Links

UXOWGYHJODZGMF-QORCZRPOSA-N Aliskiren Chemical compound COCCCOC1=CC(C[C@@H](C[C@H](N)[C@@H](O)C[C@@H](C(C)C)C(=O)NCC(C)(C)C(N)=O)C(C)C)=CC=C1OC UXOWGYHJODZGMF-QORCZRPOSA-N 0.000 title abstract 3
239000004072 C09CA03 - Valsartan Substances 0.000 title abstract 3
229960004601 aliskiren Drugs 0.000 title abstract 3
SJSNUMAYCRRIOM-QFIPXVFZSA-N valsartan Chemical compound C1=CC(CN(C(=O)CCCC)[C@@H](C(C)C)C(O)=O)=CC=C1C1=CC=CC=C1C1=NN=N[N]1 SJSNUMAYCRRIOM-QFIPXVFZSA-N 0.000 title abstract 3
229960004699 valsartan Drugs 0.000 title abstract 3
229940000425 combination drug Drugs 0.000 abstract 3
238000004090 dissolution Methods 0.000 abstract 2
150000003839 salts Chemical class 0.000 abstract 2
238000000338 in vitro Methods 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Epidemiology (AREA)
Cardiology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Heart & Thoracic Surgery (AREA)
Neurology (AREA)
Diabetes (AREA)
Pain & Pain Management (AREA)
Urology & Nephrology (AREA)
Hospice & Palliative Care (AREA)
Hematology (AREA)
Obesity (AREA)
Vascular Medicine (AREA)
Psychiatry (AREA)
Endocrinology (AREA)
Rheumatology (AREA)
Emergency Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

AT08835893T 2007-09-28 2008-09-24 Pharmazeutische kombination aus aliskiren und valsartan ATE505203T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US97590507P	2007-09-28	2007-09-28
PCT/US2008/077417 WO2009045796A1 (en)	2007-09-28	2008-09-24	Pharmaceutical combination of aliskiren and valsartan

Publications (1)

Publication Number	Publication Date
ATE505203T1 true ATE505203T1 (de)	2011-04-15

Family

ID=40394241

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT08835893T ATE505203T1 (de)	2007-09-28	2008-09-24	Pharmazeutische kombination aus aliskiren und valsartan

Country Status (16)

Country	Link
US (1)	US20100247645A1 (de)
EP (1)	EP2205279B1 (de)
JP (1)	JP2010540548A (de)
KR (1)	KR20100059912A (de)
CN (1)	CN101808665A (de)
AT (1)	ATE505203T1 (de)
AU (1)	AU2008309059A1 (de)
BR (1)	BRPI0817275A2 (de)
CA (1)	CA2697437A1 (de)
DE (1)	DE602008006243D1 (de)
ES (1)	ES2364538T3 (de)
MX (1)	MX2010003439A (de)
PL (1)	PL2205279T3 (de)
PT (1)	PT2205279E (de)
RU (1)	RU2010116526A (de)
WO (1)	WO2009045796A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN102300558A (zh) *	2009-01-28	2011-12-28	诺瓦提斯公司	有机化合物的盖伦制剂
CN102348452A (zh) *	2009-03-20	2012-02-08	诺瓦提斯公司	缬沙坦和阿利吉仑的固定剂量组合的盖仑制剂
AR080683A1 (es) *	2010-03-16	2012-05-02	Novartis Ag	Composiciones farmaceuticas de aliskiren y metodos de administracion
SG174658A1 (en)	2010-04-01	2011-10-28	Theravida Inc	Pharmaceutical formulations for the treatment of overactive bladder
WO2012154774A1 (en)	2011-05-10	2012-11-15	Theravida, Inc.	Combinations of solifenacin and salivary stimulants for the treatment of overactive bladder
CN102247344A (zh) *	2011-05-30	2011-11-23	北京阜康仁生物制药科技有限公司	一种新型降血压组合物
CN102626395B (zh) *	2012-04-19	2014-02-26	海南美兰史克制药有限公司	一种阿利克仑缬沙坦药物组合物脂质体固体制剂
WO2013166114A1 (en) *	2012-05-01	2013-11-07	Althera Life Sciences, Llc	Oral tablet formulation consisting of fixed combination of atorvastatin and ezetimibe
EP2844233B1 (de) *	2012-05-01	2020-05-06	Althera Life Sciences, LLC	Orale tablettenformulierung aus einer fixierten kombination aus rosuvastatin und ezetimib zur behandlung von hyperlipidämie und herz-kreislauf-erkrankungen
US10376470B2 (en) *	2012-05-01	2019-08-13	Althera Life Sciences, Llc	Oral tablet formulation consisting of fixed combination of rosuvastatin and ezetimibe for treatment of hyperlipidemia and cardiovascular diseases
WO2017127073A1 (en)	2016-01-20	2017-07-27	Theravida, Inc.	Methods and compositions for treating hyperhidrosis

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US7374779B2 (en) *	1999-02-26	2008-05-20	Lipocine, Inc.	Pharmaceutical formulations and systems for improved absorption and multistage release of active agents
AR048431A1 (es) *	2004-03-17	2006-04-26	Novartis Ag	Formulaciones galenicas de compuestos organicos
EP2248520A3 (de) *	2004-10-08	2010-11-17	Novartis AG	Verwendung von Reninhemmern zur Prävention oder Behandlung von diastolischer Dysfunktion oder diastolischer Herzinsuffizienz
JP2008538549A (ja) *	2005-03-22	2008-10-30	ノバルティスアクチエンゲゼルシャフト	高血圧剤としてのアリスキレンの有効性に関するバイオマーカー
CN101247832B (zh) *	2005-06-27	2011-12-28	第一三共株式会社	含有血管紧张素ⅱ受体拮抗剂和钙通道阻断剂的药物制剂

2008
- 2008-09-24 WO PCT/US2008/077417 patent/WO2009045796A1/en not_active Ceased
- 2008-09-24 CN CN200880108475A patent/CN101808665A/zh active Pending
- 2008-09-24 DE DE602008006243T patent/DE602008006243D1/de active Active
- 2008-09-24 US US12/679,052 patent/US20100247645A1/en not_active Abandoned
- 2008-09-24 MX MX2010003439A patent/MX2010003439A/es active IP Right Grant
- 2008-09-24 EP EP08835893A patent/EP2205279B1/de not_active Not-in-force
- 2008-09-24 AT AT08835893T patent/ATE505203T1/de active
- 2008-09-24 PT PT08835893T patent/PT2205279E/pt unknown
- 2008-09-24 CA CA2697437A patent/CA2697437A1/en not_active Abandoned
- 2008-09-24 BR BRPI0817275-7A patent/BRPI0817275A2/pt not_active IP Right Cessation
- 2008-09-24 AU AU2008309059A patent/AU2008309059A1/en not_active Abandoned
- 2008-09-24 JP JP2010527092A patent/JP2010540548A/ja active Pending
- 2008-09-24 KR KR1020107006602A patent/KR20100059912A/ko not_active Withdrawn
- 2008-09-24 ES ES08835893T patent/ES2364538T3/es active Active
- 2008-09-24 PL PL08835893T patent/PL2205279T3/pl unknown
- 2008-09-24 RU RU2010116526/15A patent/RU2010116526A/ru not_active Application Discontinuation

Also Published As

Publication number	Publication date
PL2205279T3 (pl)	2011-09-30
KR20100059912A (ko)	2010-06-04
AU2008309059A1 (en)	2009-04-09
BRPI0817275A2 (pt)	2015-06-16
US20100247645A1 (en)	2010-09-30
DE602008006243D1 (de)	2011-05-26
RU2010116526A (ru)	2011-11-10
MX2010003439A (es)	2010-04-21
CA2697437A1 (en)	2009-04-09
EP2205279B1 (de)	2011-04-13
PT2205279E (pt)	2011-07-11
WO2009045796A1 (en)	2009-04-09
CN101808665A (zh)	2010-08-18
ES2364538T3 (es)	2011-09-06
JP2010540548A (ja)	2010-12-24
EP2205279A1 (de)	2010-07-14

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2011-12-15

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