ATE505205T1 - Polymerkonjugate von box-a von hmgb1 und box-a- varianten von hmgb1 - Google Patents
Polymerkonjugate von box-a von hmgb1 und box-a- varianten von hmgb1Info
- Publication number
- ATE505205T1 ATE505205T1 AT07818168T AT07818168T ATE505205T1 AT E505205 T1 ATE505205 T1 AT E505205T1 AT 07818168 T AT07818168 T AT 07818168T AT 07818168 T AT07818168 T AT 07818168T AT E505205 T1 ATE505205 T1 AT E505205T1
- Authority
- AT
- Austria
- Prior art keywords
- hmgb1
- box
- polymer conjugates
- variants
- conjugates
- Prior art date
Links
- 101100339431 Arabidopsis thaliana HMGB2 gene Proteins 0.000 title abstract 9
- 102000055207 HMGB1 Human genes 0.000 title abstract 9
- 108700010013 HMGB1 Proteins 0.000 title abstract 9
- 101150021904 HMGB1 gene Proteins 0.000 title abstract 9
- 229920000642 polymer Polymers 0.000 title abstract 3
- OUFUEOCARHOWCD-DAXSKMNVSA-N BOX A Chemical compound CC1=C(C=C)\C(=C\C(N)=O)NC1=O OUFUEOCARHOWCD-DAXSKMNVSA-N 0.000 title 2
- 229920001184 polypeptide Polymers 0.000 abstract 3
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 3
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 3
- 239000012634 fragment Substances 0.000 abstract 1
- 230000007170 pathology Effects 0.000 abstract 1
Landscapes
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP06019362 | 2006-09-15 | ||
| US90477607P | 2007-03-05 | 2007-03-05 | |
| PCT/EP2007/008029 WO2008031612A1 (en) | 2006-09-15 | 2007-09-14 | Polymer conjugates of box-a of hmgb1 and box-a variants of hmgb1 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE505205T1 true ATE505205T1 (de) | 2011-04-15 |
Family
ID=41095680
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT07818168T ATE505205T1 (de) | 2006-09-15 | 2007-09-14 | Polymerkonjugate von box-a von hmgb1 und box-a- varianten von hmgb1 |
Country Status (8)
| Country | Link |
|---|---|
| CN (1) | CN101528266B (de) |
| AT (1) | ATE505205T1 (de) |
| BR (1) | BRPI0718491A2 (de) |
| DE (1) | DE602007013919D1 (de) |
| DK (1) | DK2068935T3 (de) |
| PT (1) | PT2068935E (de) |
| RU (1) | RU2458070C2 (de) |
| SI (1) | SI2068935T1 (de) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102113809B1 (ko) * | 2011-04-26 | 2020-05-21 | 가부시키가이샤 스템림 | 조직 재생을 유도하기 위한 펩티드 및 그의 이용 |
| CN102443064A (zh) * | 2011-11-03 | 2012-05-09 | 刘誉 | 一种基于凝血酶活性的双靶向作用的嵌合多肽及其应用 |
| CN103893754A (zh) * | 2012-12-26 | 2014-07-02 | 深圳先进技术研究院 | Dna-壳聚糖复合纳米颗粒、其制备及应用 |
| US9775885B2 (en) * | 2016-01-29 | 2017-10-03 | Kaohsiung Medical Univeristy | TMD1 protein for treating bone loss diseases |
| WO2019156137A1 (ja) | 2018-02-08 | 2019-08-15 | 株式会社ステムリム | 乾癬の治療薬 |
| US12304933B2 (en) | 2018-10-05 | 2025-05-20 | StemRIM Inc. | Disease treatment drug based on mesenchymal-stem-cell mobilization |
| JP7448126B2 (ja) * | 2018-10-25 | 2024-03-12 | 国立大学法人大阪大学 | 軟骨疾患の治療薬 |
| CN114957440A (zh) * | 2022-05-26 | 2022-08-30 | 江苏大学 | 一种重组HMGB1 A Box蛋白及其获取方法与应用 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR0209689A (pt) * | 2001-05-15 | 2006-02-07 | Long Island Jewish Res Inst | Uso de fragmento de hmg como agente anti-inflamatório |
| EP1814576A2 (de) * | 2004-07-20 | 2007-08-08 | Critical Therapeutics, Inc. | Kombinationstherapien von hmgb- und komplementinhibitoren gegen entzündungen |
| AU2005279308B2 (en) * | 2004-09-03 | 2012-05-03 | Creabilis Therapeutics S.R.L. | Protease resistant human and non-human HMGB1 Box-A mutants and their therapeutic/diagnostic use |
-
2007
- 2007-09-14 RU RU2009114149/10A patent/RU2458070C2/ru not_active IP Right Cessation
- 2007-09-14 AT AT07818168T patent/ATE505205T1/de active
- 2007-09-14 SI SI200730617T patent/SI2068935T1/sl unknown
- 2007-09-14 DE DE602007013919T patent/DE602007013919D1/de active Active
- 2007-09-14 BR BRPI0718491-3A patent/BRPI0718491A2/pt not_active Application Discontinuation
- 2007-09-14 DK DK07818168.2T patent/DK2068935T3/da active
- 2007-09-14 CN CN200780040422.XA patent/CN101528266B/zh not_active Expired - Fee Related
- 2007-09-14 PT PT07818168T patent/PT2068935E/pt unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE602007013919D1 (de) | 2011-05-26 |
| RU2009114149A (ru) | 2010-10-20 |
| CN101528266B (zh) | 2012-11-07 |
| SI2068935T1 (sl) | 2011-07-29 |
| PT2068935E (pt) | 2011-07-08 |
| DK2068935T3 (da) | 2011-08-01 |
| BRPI0718491A2 (pt) | 2013-12-03 |
| CN101528266A (zh) | 2009-09-09 |
| RU2458070C2 (ru) | 2012-08-10 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MX2009002820A (es) | Conjugados polimericos de box-a de hmgb1 y variantes de box-a de hmgb1. | |
| NL301089I1 (de) | ||
| CY1121198T1 (el) | Αντινοημaτικα μορια και μεθοδοι για την θεραπεια παθολογιων | |
| MX2009007290A (es) | Compuestos agonistas del receptor de la proteina 1 similar al glucagon. | |
| EA201070517A1 (ru) | Устойчивый к окислителям аполипопротеин а-1 и пептиды-миметики | |
| EA201590910A1 (ru) | Белки на основе структурного домена фибронектина, связывающие pcsk9 | |
| DE602007010664D1 (de) | P53 aktivierende benzoylharnstoff- und benzoylthioharnstoff-verbindungen | |
| DE602005021072D1 (de) | Adzyme und deren verwendungen | |
| BRPI0820500A2 (pt) | Variantes de alfa-amilase de bacillus sp. Ts-23 com propriedades alteradas | |
| NO20091181L (no) | Anti-C5AR-antistoffer med forbedrede egenskaper | |
| DK1934353T3 (da) | IL-15R alpha sushi domæner som en selektiv og effektiv forstærker af IL-15-virkningen gennem IL-15Rbeta/gamma, i hyperagonist IL-15 Ralpha sushi -IL 15 fusionsproteiner | |
| ATE538650T1 (de) | Cannabinoid-rezeptor-antagonisten / inverse agonisten zur behandlung von übergewicht | |
| EA201171220A1 (ru) | Мутанты fgf21 и их применение | |
| EP2493506A4 (de) | Il-17a-antagonisten | |
| MX2009005053A (es) | Emulsiones bituminosas. | |
| MX338754B (es) | Anticuerpos humanos contra el factor tisular. | |
| NZ588033A (en) | Methods of treating a mif-mediated disorder | |
| NO20074943L (no) | Roflumilast for behandlingen av diabetes mellitus | |
| EA016245B9 (ru) | Антитела против альфа2-интегрина и их применение | |
| EP2195331A4 (de) | Synthetische, apolipoprotein e nachahmende polypeptide und anwendungsverfahren | |
| EA201070609A1 (ru) | Способы лечения ожирения и ассоциированных с ожирением заболеваний и расстройств | |
| CR20110202A (es) | Antagonistas de la via hedgehog de ftalazina disustituida | |
| ATE484505T1 (de) | 5-sulfanylmethylä1,2,4ütriazolä1,5-aüpyrimidin- - olderivate als cxcr2-antagonisten | |
| DE602006017331D1 (de) | Kontrollierte produktion und zuführung biologisch aktiver stoffe durch darmbakterien | |
| EA200800667A1 (ru) | Аптамеры, связывающие тромбин с высокой аффинностью |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 2068935 Country of ref document: EP |