ATE506079T1 - Verbindungsgewebe und vernetzungsproteine mit naphthalimid-verbindungen - Google Patents
Verbindungsgewebe und vernetzungsproteine mit naphthalimid-verbindungenInfo
- Publication number
- ATE506079T1 ATE506079T1 AT08075902T AT08075902T ATE506079T1 AT E506079 T1 ATE506079 T1 AT E506079T1 AT 08075902 T AT08075902 T AT 08075902T AT 08075902 T AT08075902 T AT 08075902T AT E506079 T1 ATE506079 T1 AT E506079T1
- Authority
- AT
- Austria
- Prior art keywords
- naphthalimide
- tissue
- bonding
- tissues
- naphthalimide compounds
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
- A61K41/0042—Photocleavage of drugs in vivo, e.g. cleavage of photolabile linkers in vivo by UV radiation for releasing the pharmacologically-active agent from the administered agent; photothrombosis or photoocclusion
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
- C08B37/0024—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid beta-D-Glucans; (beta-1,3)-D-Glucans, e.g. paramylon, coriolan, sclerotan, pachyman, callose, scleroglucan, schizophyllan, laminaran, lentinan or curdlan; (beta-1,6)-D-Glucans, e.g. pustulan; (beta-1,4)-D-Glucans; (beta-1,3)(beta-1,4)-D-Glucans, e.g. lichenan; Derivatives thereof
- C08B37/0027—2-Acetamido-2-deoxy-beta-glucans; Derivatives thereof
- C08B37/003—Chitin, i.e. 2-acetamido-2-deoxy-(beta-1,4)-D-glucan or N-acetyl-beta-1,4-D-glucosamine; Chitosan, i.e. deacetylated product of chitin or (beta-1,4)-D-glucosamine; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/08—Wound clamps or clips, i.e. not or only partly penetrating the tissue ; Devices for bringing together the edges of a wound
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/716—Glucans
- A61K31/722—Chitin, chitosan
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
- A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/61—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/736—Chitin; Chitosan; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
- A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
- A61L24/08—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N5/0613—Apparatus adapted for a specific treatment
- A61N5/062—Photodynamic therapy, i.e. excitation of an agent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/16—Emollients or protectives, e.g. against radiation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/57—Compounds covalently linked to a(n inert) carrier molecule, e.g. conjugates, pro-fragrances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/81—Preparation or application process involves irradiation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/94—Involves covalent bonding to the substrate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N5/0601—Apparatus for use inside the body
- A61N2005/0602—Apparatus for use inside the body for treatment of blood vessels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N2005/0658—Radiation therapy using light characterised by the wavelength of light used
- A61N2005/0662—Visible light
- A61N2005/0663—Coloured light
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Dermatology (AREA)
- Molecular Biology (AREA)
- Surgery (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Informatics (AREA)
- Biochemistry (AREA)
- Birds (AREA)
- Pathology (AREA)
- Radiology & Medical Imaging (AREA)
- Biophysics (AREA)
- Materials Engineering (AREA)
- Polymers & Plastics (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Toxicology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Materials For Medical Uses (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US51761803P | 2003-11-05 | 2003-11-05 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE506079T1 true ATE506079T1 (de) | 2011-05-15 |
Family
ID=34572957
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT08075902T ATE506079T1 (de) | 2003-11-05 | 2004-11-05 | Verbindungsgewebe und vernetzungsproteine mit naphthalimid-verbindungen |
Country Status (7)
| Country | Link |
|---|---|
| US (9) | US7514399B2 (de) |
| EP (2) | EP1689441A1 (de) |
| AT (1) | ATE506079T1 (de) |
| CA (1) | CA2586320A1 (de) |
| DE (1) | DE602004032400D1 (de) |
| ES (1) | ES2371501T3 (de) |
| WO (1) | WO2005044309A1 (de) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2003282683A1 (en) * | 2002-10-04 | 2004-05-04 | Photokinetix Inc. | Photokinetic delivery of biologically active substances using pulsed incoherent light |
| ATE506079T1 (de) * | 2003-11-05 | 2011-05-15 | Photobiomed Corp | Verbindungsgewebe und vernetzungsproteine mit naphthalimid-verbindungen |
| US20060246020A1 (en) * | 2005-04-29 | 2006-11-02 | Cole Curtis A | Topical composition detection |
| BRPI0807065A2 (pt) * | 2007-01-31 | 2017-03-21 | Allergan Inc | biomateriais novos para liberação de fármaco ocular e um método para fazer e usar os mesmos |
| EP1955710A1 (de) * | 2007-02-09 | 2008-08-13 | The Jordanian Pharmaceutical Manufacturing Co. | Wässrige Zusammensetzung, die Chitosan und eine säurehaltige Substanz umfasst |
| GB0721194D0 (en) * | 2007-10-29 | 2007-12-05 | Ucl Business Plc | Luminescence |
| WO2009064838A1 (en) * | 2007-11-15 | 2009-05-22 | Amgen, Inc. | Aqueous formulation of erythropoiesis stimulating protein stablised by antioxidants for parenteral administration |
| CN103547226B (zh) | 2011-01-28 | 2018-04-17 | 通用医疗公司 | 用于皮肤再表面化的装置 |
| WO2012103483A2 (en) | 2011-01-28 | 2012-08-02 | The General Hospital Corporation | Apparatus and method for tissue biopsy |
| US9561051B2 (en) | 2011-01-28 | 2017-02-07 | The General Hospital Corporation | Method and apparatus for discontinuous dermabrasion |
| ES2693162T3 (es) | 2011-07-21 | 2018-12-07 | The General Hospital Corporation | Instrumental para dañar y eliminar grasa |
| WO2014015274A1 (en) * | 2012-07-20 | 2014-01-23 | The General Hospital Corporation | Methods for tissue passivation |
| WO2014022807A2 (en) * | 2012-08-03 | 2014-02-06 | Alumend, Llc | Compositions and methods of using the compositions for plaque softening |
| WO2014113450A1 (en) | 2013-01-16 | 2014-07-24 | Alumend, Llc | Decreasing inflammatory response in a blood vessel |
| EP4039236A1 (de) | 2013-02-20 | 2022-08-10 | Cytrellis Biosystems, Inc. | System zur hautstraffung |
| US10131635B2 (en) | 2013-03-15 | 2018-11-20 | Alumend, Llc | Compositions and methods of using the compositions for plaque softening |
| EP3763371B1 (de) | 2013-03-15 | 2024-03-06 | Alumend, LLC | Verfahren zur akuten wiederherstellung von vaskulärer compliance |
| AU2014259645B2 (en) | 2013-05-03 | 2019-05-02 | Cytrellis Biosystems, Inc. | Microclosures and related methods for skin treatment |
| EP3030175B1 (de) | 2013-08-09 | 2023-10-04 | Cytrellis Biosystems, Inc. | Vorrichtungen zur hautbehandlung mittels nichtthermischer gewebeablation |
| US10953143B2 (en) | 2013-12-19 | 2021-03-23 | Cytrellis Biosystems, Inc. | Methods and devices for manipulating subdermal fat |
| CN103864686B (zh) * | 2014-03-14 | 2015-09-30 | 中国海洋石油总公司 | 一种萘酰亚胺季铵盐的微波常压合成方法 |
| BR112017009805A2 (pt) | 2014-11-14 | 2017-12-26 | Cytrellis Biosystems Inc | dispositivos e métodos para ablação da pele |
| KR102561605B1 (ko) | 2016-03-29 | 2023-08-01 | 사이트렐리스 바이오시스템즈, 인크. | 미용 피부 리설페이싱용 디바이스 및 방법 |
| KR102515836B1 (ko) | 2016-09-21 | 2023-03-31 | 사이트렐리스 바이오시스템즈, 인크. | 미용 피부 리설페이싱용 디바이스 및 방법 |
| US11344507B2 (en) | 2019-01-08 | 2022-05-31 | Alumend, Llc | Topical compositions containing low molecular weight chitosan derivatives |
| EP4010058A1 (de) | 2019-08-07 | 2022-06-15 | W.L. Gore & Associates, Inc. | Ballonfreisetzungsvorrichtung für ein lichtaktivierbares behandlungsmedium |
| CN111978433A (zh) * | 2020-07-20 | 2020-11-24 | 南京林业大学 | N-壳聚糖基-4-羟基-1,8-萘二甲酰亚胺荧光材料及其制备方法与应用 |
| US20240238611A1 (en) | 2021-06-08 | 2024-07-18 | W. L. Gore & Associates, Inc. | Treatment media delivery device and methods for targeted delivery thereof |
| CN113856005A (zh) * | 2021-09-26 | 2021-12-31 | 复旦大学附属中山医院 | 一种促进组织修复和纤维连接的药物涂层球囊导管组件及其使用方法 |
| CN116265036A (zh) * | 2021-12-17 | 2023-06-20 | 杭州矩正医疗科技有限公司 | 一种原位生成血管支架的球囊导管系统 |
| CN116407739A (zh) * | 2021-12-29 | 2023-07-11 | 杭州矩正医疗科技有限公司 | 载药球囊导管 |
| US12295949B2 (en) | 2022-08-07 | 2025-05-13 | Alumend, Llc | Treatment of the gastrointestinal tract with dimeric naphthalimide compounds |
| JP2025530802A (ja) * | 2022-09-02 | 2025-09-17 | 杭州矩正医療科技有限公司 | 薬物載置バルーンカテーテルおよびその作製方法、バルーンカテーテルシステムおよび血管インサイチューステント生成方法 |
| CN115737914B (zh) * | 2022-11-25 | 2024-02-06 | 杭州矩正医疗科技有限公司 | 一种具有血管修复功能的感光材料制备方法 |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2574184B1 (fr) * | 1984-11-30 | 1988-04-22 | Centre Nat Rech Scient | Composes fluorescents, derives d'(amino-4 disulfonato-3,6) naphtalimide, leur application aux dosages immunologiques en polarisation de fluorescence |
| US5177083A (en) | 1986-07-03 | 1993-01-05 | The Scripps Clinic And Research Foundation | Drugs effective against retroviruses |
| US5308604A (en) * | 1989-04-19 | 1994-05-03 | Deutsches Krebsforschungsinstitut | Conjugates for tumor localization and/or tumor therapy |
| BR9306038A (pt) * | 1992-02-28 | 1998-01-13 | Univ Texas | Hidrogéis biodegradáveis fotopolimerizáveis como materiais de contato de tecidos e condutores de liberação controlada |
| US5235045A (en) * | 1992-03-19 | 1993-08-10 | Microbiomed Corporation | Non-azo naphthalimide dyes |
| US5766600A (en) * | 1993-08-09 | 1998-06-16 | Microbiomed Corporation | Non-azo naphtalimide dyes and uses for same |
| US5431639A (en) * | 1993-08-12 | 1995-07-11 | Boston Scientific Corporation | Treating wounds caused by medical procedures |
| IL110460A (en) * | 1993-08-18 | 2001-01-11 | Basf Ag | Bis-naphthalimides, their preparation and pharmaceutical compositions containing them |
| US6410505B1 (en) * | 1999-06-28 | 2002-06-25 | Microbiomed Corp. | Dimeric non-azo naphthalimides and uses for the same |
| US5917045A (en) | 1995-06-07 | 1999-06-29 | Microbiomed Corporation | Dimeric non-azo naphthalimides and uses for same |
| EP0851768B1 (de) * | 1995-09-01 | 2002-04-24 | University of Washington | Interaktive molekulare konjugate |
| GB9920774D0 (en) * | 1999-09-03 | 1999-11-03 | Avecia Ltd | Polymer |
| US20030206958A1 (en) * | 2000-12-22 | 2003-11-06 | Cattaneo Maurizio V. | Chitosan biopolymer for the topical delivery of active agents |
| AU2001240054B2 (en) * | 2000-03-07 | 2005-08-11 | The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | 1,8-Naphthalimide Imidazo[4,5,1-de]acridones with Anti-Tumor Activity |
| KR20030038814A (ko) * | 2000-10-11 | 2003-05-16 | 타게솜, 인크. | 표적 치료제 |
| AU2003217782A1 (en) * | 2002-02-27 | 2003-09-09 | The Government Of The United States Of America, Representated By The Secretary, Deparment Of Health | Dna-binding polyamide drug conjugates |
| ATE506079T1 (de) * | 2003-11-05 | 2011-05-15 | Photobiomed Corp | Verbindungsgewebe und vernetzungsproteine mit naphthalimid-verbindungen |
| US7947839B2 (en) * | 2004-12-01 | 2011-05-24 | Genentech, Inc. | Heterocyclic-substituted bis-1,8 naphthalimide compounds, antibody drug conjugates, and methods of use |
-
2004
- 2004-11-05 AT AT08075902T patent/ATE506079T1/de not_active IP Right Cessation
- 2004-11-05 US US10/982,197 patent/US7514399B2/en not_active Expired - Lifetime
- 2004-11-05 CA CA002586320A patent/CA2586320A1/en not_active Abandoned
- 2004-11-05 EP EP04810395A patent/EP1689441A1/de not_active Withdrawn
- 2004-11-05 ES ES08075902T patent/ES2371501T3/es not_active Expired - Lifetime
- 2004-11-05 EP EP08075902A patent/EP2047866B1/de not_active Expired - Lifetime
- 2004-11-05 DE DE602004032400T patent/DE602004032400D1/de not_active Expired - Lifetime
- 2004-11-05 WO PCT/US2004/036914 patent/WO2005044309A1/en not_active Ceased
-
2009
- 2009-03-19 US US12/407,481 patent/US8242114B2/en not_active Expired - Lifetime
-
2012
- 2012-07-12 US US13/547,196 patent/US8546384B2/en not_active Expired - Fee Related
-
2013
- 2013-02-21 US US13/772,543 patent/US8632565B2/en not_active Expired - Fee Related
- 2013-02-21 US US13/772,510 patent/US8741270B2/en not_active Expired - Lifetime
-
2014
- 2014-06-02 US US14/293,729 patent/US9125938B2/en not_active Expired - Lifetime
-
2015
- 2015-09-02 US US14/843,586 patent/US9822189B2/en not_active Expired - Fee Related
-
2017
- 2017-11-17 US US15/815,855 patent/US10053521B2/en not_active Expired - Lifetime
-
2018
- 2018-08-20 US US15/999,547 patent/US10851185B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US20050113288A1 (en) | 2005-05-26 |
| WO2005044309A1 (en) | 2005-05-19 |
| CA2586320A1 (en) | 2005-05-19 |
| US8741270B2 (en) | 2014-06-03 |
| US20090181927A1 (en) | 2009-07-16 |
| US8546384B2 (en) | 2013-10-01 |
| EP2047866B1 (de) | 2011-04-20 |
| DE602004032400D1 (de) | 2011-06-01 |
| EP1689441A1 (de) | 2006-08-16 |
| US8242114B2 (en) | 2012-08-14 |
| US20140350453A1 (en) | 2014-11-27 |
| US20190241680A1 (en) | 2019-08-08 |
| US20130165970A1 (en) | 2013-06-27 |
| US9822189B2 (en) | 2017-11-21 |
| US7514399B2 (en) | 2009-04-07 |
| US9125938B2 (en) | 2015-09-08 |
| US20130230472A1 (en) | 2013-09-05 |
| US10053521B2 (en) | 2018-08-21 |
| US10851185B2 (en) | 2020-12-01 |
| US20130045171A1 (en) | 2013-02-21 |
| US8632565B2 (en) | 2014-01-21 |
| ES2371501T3 (es) | 2012-01-03 |
| US20180079833A1 (en) | 2018-03-22 |
| US20160068614A1 (en) | 2016-03-10 |
| EP2047866A1 (de) | 2009-04-15 |
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