ATE506430T1 - Vorrichtung und verfahren zur reduzierung der bläschenbildung in einer zellkultur - Google Patents

Vorrichtung und verfahren zur reduzierung der bläschenbildung in einer zellkultur

Info

Publication number
ATE506430T1
ATE506430T1 AT08725509T AT08725509T ATE506430T1 AT E506430 T1 ATE506430 T1 AT E506430T1 AT 08725509 T AT08725509 T AT 08725509T AT 08725509 T AT08725509 T AT 08725509T AT E506430 T1 ATE506430 T1 AT E506430T1
Authority
AT
Austria
Prior art keywords
cell culture
bubble formation
reducing bubble
formation
bubbles
Prior art date
Application number
AT08725509T
Other languages
English (en)
Inventor
David Kenney
Gregory Martin
Allison Tanner
Joseph Wall
Original Assignee
Corning Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Corning Inc filed Critical Corning Inc
Application granted granted Critical
Publication of ATE506430T1 publication Critical patent/ATE506430T1/de

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/08—Flasks
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/02—Form or structure of the vessel
    • C12M23/08—Flask, bottle or test tube
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/34—Internal compartments or partitions
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/40—Manifolds; Distribution pieces
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/02—Means for regulation, monitoring, measurement or control, e.g. flow regulation of foam

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Sustainable Development (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT08725509T 2007-02-26 2008-02-13 Vorrichtung und verfahren zur reduzierung der bläschenbildung in einer zellkultur ATE506430T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11/710,815 US7897379B2 (en) 2007-02-26 2007-02-26 Device and method for reducing bubble formation in cell culture
PCT/US2008/001885 WO2008106012A1 (en) 2007-02-26 2008-02-13 Device and method for reducing bubble formation in cell culture

Publications (1)

Publication Number Publication Date
ATE506430T1 true ATE506430T1 (de) 2011-05-15

Family

ID=39471943

Family Applications (1)

Application Number Title Priority Date Filing Date
AT08725509T ATE506430T1 (de) 2007-02-26 2008-02-13 Vorrichtung und verfahren zur reduzierung der bläschenbildung in einer zellkultur

Country Status (6)

Country Link
US (1) US7897379B2 (de)
EP (1) EP2118259B1 (de)
JP (1) JP5088756B2 (de)
AT (1) ATE506430T1 (de)
DE (1) DE602008006361D1 (de)
WO (1) WO2008106012A1 (de)

Families Citing this family (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101120083B (zh) 2003-10-08 2013-03-27 威尔森沃尔夫制造公司 利用透气性材料进行细胞培养的方法及装置
US7745209B2 (en) 2005-07-26 2010-06-29 Corning Incorporated Multilayered cell culture apparatus
US7820431B2 (en) 2005-12-30 2010-10-26 Corning Incorporated Device for trapping extraneous gas
US20080176318A1 (en) * 2006-12-07 2008-07-24 Wilson John R Highly efficient devices and methods for culturing cells
US8178345B2 (en) * 2008-05-30 2012-05-15 Corning Incorporated Multilayer cell culture vessels
JP5395171B2 (ja) * 2008-07-08 2014-01-22 ウィルソン ウォルフ マニュファクチャリング コーポレイション 気体透過性の細胞培養装置および使用方法
EP2304019B1 (de) * 2008-07-16 2019-04-10 EMD Millipore Corporation Schichtiges kolbensystem zur kultivierung von zellen
EP2401353B1 (de) * 2009-02-25 2015-04-29 Corning Incorporated Zellkultursystem mit verteiler
US8778669B2 (en) 2009-07-22 2014-07-15 Corning Incorporated Multilayer tissue culture vessel
EP2627572A4 (de) * 2010-10-12 2017-12-13 Nalge Nunc International Corporation Entlüftungsverschluss mit einem port
WO2013022670A1 (en) * 2011-08-05 2013-02-14 Joule Unlimited Technologies, Inc. Flexible photobioreactors, systems and methods
KR20130058954A (ko) * 2011-11-28 2013-06-05 삼성전기주식회사 배양 용기 및 이의 시료 주입 방법
JP5912734B2 (ja) * 2012-03-26 2016-04-27 テルモ株式会社 細胞培養装置
US9005550B2 (en) 2012-10-29 2015-04-14 Corning Incorporated Multi-layered cell culture vessel with manifold grips
EP2757148B1 (de) * 2013-01-18 2015-12-16 Eppendorf Ag Kulturflasche
US10058866B2 (en) 2013-03-13 2018-08-28 Abbott Laboratories Methods and apparatus to mitigate bubble formation in a liquid
US9535082B2 (en) 2013-03-13 2017-01-03 Abbott Laboratories Methods and apparatus to agitate a liquid
USD978375S1 (en) 2013-03-13 2023-02-14 Abbott Laboratories Reagent container
USD962471S1 (en) 2013-03-13 2022-08-30 Abbott Laboratories Reagent container
JP6169869B2 (ja) * 2013-03-22 2017-07-26 株式会社スペース・バイオ・ラボラトリーズ 細胞培養容器
JP6153357B2 (ja) * 2013-03-22 2017-06-28 株式会社スペース・バイオ・ラボラトリーズ 細胞培養容器
US9790465B2 (en) 2013-04-30 2017-10-17 Corning Incorporated Spheroid cell culture well article and methods thereof
JP2015050964A (ja) * 2013-09-06 2015-03-19 住友ベークライト株式会社 多段式培養フラスコおよび細胞培養フラスコの製造方法
KR101532282B1 (ko) * 2013-12-13 2015-06-30 한국원자력연구원 입자빔을 이용한 동물 세포 사멸 실험용 용기
US20160053293A1 (en) 2014-08-25 2016-02-25 Idexx Laboratories Inc. Multi-well sample testing apparatus and methods of sample testing using the same
EP3212759A1 (de) 2014-10-29 2017-09-06 Corning Incorporated Zellkultureinsatz
JP2017532971A (ja) 2014-10-29 2017-11-09 コーニング インコーポレイテッド 細胞培養集合体を生成するためのマイクロウェル設計および製造
EP3212760A1 (de) 2014-10-29 2017-09-06 Corning Incorporated Perfusionsbioreaktorplattform
MX2018014681A (es) 2016-06-03 2019-06-06 Lonza Ag Biorreactor de un solo uso.
CN106497792B (zh) * 2016-11-11 2019-09-20 新奥科技发展有限公司 一种光生物细胞的培养方法
KR102499475B1 (ko) 2017-02-10 2023-02-15 론자 리미티드 세포 배양 시스템 및 방법
JP7245222B2 (ja) 2017-07-14 2023-03-23 コーニング インコーポレイテッド 手動又は自動で培地を交換するための３ｄ細胞培養容器
JP7197557B2 (ja) 2017-07-14 2022-12-27 コーニング インコーポレイテッド 多孔性支持体を有する細胞培養槽
PL3652292T3 (pl) 2017-07-14 2025-09-01 Corning Incorporated Naczynie do hodowli komórkowej 3d i sposoby hodowli komórkowej 3d
US11857970B2 (en) 2017-07-14 2024-01-02 Corning Incorporated Cell culture vessel
WO2019014627A1 (en) * 2017-07-14 2019-01-17 Corning Incorporated HANDLING ELEMENTS FOR MICROCAVITY CELL CULTURE CONTAINER
WO2019090211A1 (en) 2017-11-06 2019-05-09 Corning Incorporated Cell culture apparatuses with manifolds including column structures
KR101989348B1 (ko) 2018-03-02 2019-06-20 한국에너지기술연구원 생물반응기 내부의 폼을 제거하는 트랩 및 이를 사용하여 미생물 배양시 발생하는 폼을 제거하는 방법
CN111065725B (zh) 2018-07-13 2024-03-29 康宁股份有限公司 包括具有互联的壁的微板的流体装置
JP7171695B2 (ja) 2018-07-13 2022-11-15 コーニング インコーポレイテッド 液体培地送達面を含む側壁を有するマイクロキャビティ皿
WO2020013845A1 (en) 2018-07-13 2020-01-16 Corning Incorporated Cell culture vessels with stabilizer devices
JP2020202784A (ja) * 2019-06-17 2020-12-24 シンフォニアテクノロジー株式会社 多層培養容器
EP3998329A4 (de) * 2019-07-08 2023-08-02 Nipro Corporation Mehrschichtiges kulturgefäss
WO2022115135A2 (en) * 2020-08-31 2022-06-02 Corning Incorporated Bioreactor system
WO2025189164A1 (en) * 2024-03-08 2025-09-12 Appraiseye, Inc. Adeno-associated virus and cell maintenance and transfection

Family Cites Families (102)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1539263A (en) 1976-11-19 1979-01-31 Toray Industries Apparatus and methods for growing cells
DE2726313C3 (de) * 1977-06-10 1980-02-07 Battelle-Institut E.V., 6000 Frankfurt Verfahren zur in-vitro-Biosynthese von Hormonen, insbesondere von Insulin
US4296205A (en) * 1980-02-22 1981-10-20 Verma Dharmvir S Cell culture and continuous dialysis flask and method
DE3409501A1 (de) 1984-03-15 1985-10-24 Sandoz-Patent-GmbH, 7850 Lörrach Verfahren zur kultivierung von zellen
US4748124A (en) * 1984-10-30 1988-05-31 E. I. Du Pont De Nemours And Company Compartmentalized cell-culture device and method
US4661455A (en) * 1986-01-16 1987-04-28 Dorr-Oliver Incorporated Membrane cell culturing device
US4770854A (en) * 1986-02-03 1988-09-13 Costar Corporation Laboratory flask
US4734373A (en) * 1986-06-24 1988-03-29 Bartal Arie H Apparatus for enhancing cell growth, preservation and transport
US4945203A (en) * 1986-11-06 1990-07-31 American Fluoroseal Corporation Method and apparatus for making fluorocarbon film plastic bags using a laser
US4935371A (en) * 1986-12-31 1990-06-19 American Sterilizer Company Sterilizable gas permeable container for use in culturing living cells
US5786215A (en) * 1987-05-20 1998-07-28 Baxter International Inc. Method for culturing animal cells
US5047347A (en) * 1987-08-17 1991-09-10 Cline Martin J Gas permeable culture flask and method for culturing mammalian cells
US4839292B1 (en) * 1987-09-11 1994-09-13 Joseph G Cremonese Cell culture flask utilizing membrane barrier
US5026650A (en) * 1988-06-30 1991-06-25 The United States Of Amercia As Represented By The Administrator Of The National Aeronautics And Space Administration Horizontally rotated cell culture system with a coaxial tubular oxygenator
US5153131A (en) * 1990-12-11 1992-10-06 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration High aspect reactor vessel and method of use
US5079168A (en) * 1988-08-10 1992-01-07 Endotronics, Inc. Cell culture apparatus
US5416022A (en) * 1988-08-10 1995-05-16 Cellex Biosciences, Inc. Cell culture apparatus
US4838196A (en) * 1988-08-30 1989-06-13 Ingram Robert T Kayak safety sponsons
JPH0738844Y2 (ja) 1988-10-07 1995-09-06 トヨタ自動車株式会社 酸素センサ用ヒータ制御装置
US5068195A (en) 1988-11-02 1991-11-26 Du Pont Merck Pharmaceutical Company Dot matrix membrane cell expansion and maintenance vessel
US5139946A (en) * 1988-11-02 1992-08-18 Du Pont Merck Pharmaceutical Company Dot matrix membrane cell expansion
JPH03164169A (ja) * 1989-08-04 1991-07-16 Mitsubishi Rayon Co Ltd 細胞培養方法
US5650325A (en) * 1990-11-29 1997-07-22 Spielmann; Richard Apparatus having a rotatable stack of parallel trays with culturing surfaces on opposite sides for liquid/gas exchange
EP0667894B1 (de) * 1991-11-15 1997-01-02 Nunc A/S Vorrichtung zur kultivierung von zellen
US5310676A (en) * 1991-11-15 1994-05-10 A/S Nunc Cell cultivating device
JP3116103B2 (ja) * 1991-11-22 2000-12-11 味の素株式会社 好気性培養による発酵生産における培養装置及び消泡制御方法
DE4206585C2 (de) * 1992-03-03 1994-11-24 Augustinus Dr Med Bader Vorrichtung zur Massenkultur von Zellen
US5330908A (en) * 1992-12-23 1994-07-19 The United States Of America As Represented By The Administrator, National Aeronautics And Space Administration High density cell culture system
US5686301A (en) * 1993-09-02 1997-11-11 Heraeus Instruments Gmbh Culture vessel for cell cultures
US5702941A (en) 1993-09-09 1997-12-30 Synthecon, Inc. Gas permeable bioreactor and method of use
US5437998A (en) * 1993-09-09 1995-08-01 Synthecon, Inc. Gas permeable bioreactor and method of use
US5763279A (en) * 1993-09-09 1998-06-09 Synthecon, Inc. Gas permeable bioreactor and method of use
US5525505A (en) * 1994-01-31 1996-06-11 Clemson University Plant propagation system and method
US5565353A (en) * 1994-06-22 1996-10-15 Board Of Regents, The University Of Texas System Perfusable culture device
US5693537A (en) 1994-06-28 1997-12-02 Wilson; John R. Compartmentalized tissue culture flask
US5714384A (en) * 1994-06-28 1998-02-03 Wilson; John R. Compartmentalized tissue culture bag
GB9413029D0 (en) * 1994-06-29 1994-08-17 Common Services Agency Stem cell immobilisation
US5523236A (en) 1994-08-18 1996-06-04 Becton, Dickinson And Company Closure assembly for cell culture vessels
US5527705A (en) * 1994-09-12 1996-06-18 Becton, Dickinson And Company Roller bottle for trans-membrane co-culture of cells and method for its use
US6297046B1 (en) * 1994-10-28 2001-10-02 Baxter International Inc. Multilayer gas-permeable container for the culture of adherent and non-adherent cells
DE19537774C2 (de) * 1994-11-18 1996-09-19 Heraeus Instr Gmbh Verfahren zur Zellkultivierung und Vorrichtung zur Durchführung des Verfahrens
EP0725134A3 (de) 1995-02-03 1998-05-13 NPBI Nederlands Produktielaboratorium voor Bloedtransfusieapparatuur en Infusievloeistoffen B.V. Flexibler Bioreaktor für therapeutische Zellen
CA2175626C (en) * 1995-05-18 1999-08-03 Timothy A. Stevens Tissue culture flask
US5602028A (en) * 1995-06-30 1997-02-11 The University Of British Columbia System for growing multi-layered cell cultures
US5627070A (en) * 1995-07-26 1997-05-06 Celltherapy, Inc. Cell growing device for in vitro cell population expansion
US5686304A (en) * 1995-12-15 1997-11-11 Avecor Cardiovascular, Inc. Cell culture apparatus and method
US5801054A (en) * 1996-09-19 1998-09-01 The United States Of America As Represented By The Secretary Of The Air Force Cell culture vessel with self-maintained atmosphere
US5783440A (en) * 1996-09-30 1998-07-21 Becton Dickinson And Company Culture vessel
US6465251B1 (en) * 1996-11-13 2002-10-15 Dana-Farber Cancer Institute, Inc. Method of promoting b-cell proliferation and activation with CD40 ligand and cyclosporin
DE19719751A1 (de) * 1997-05-10 1998-11-12 Augustinus Dr Med Bader Vorrichtung zum Züchten und/oder Behandeln von Zellen
US6548263B1 (en) * 1997-05-29 2003-04-15 Cellomics, Inc. Miniaturized cell array methods and apparatus for cell-based screening
US7160687B1 (en) * 1997-05-29 2007-01-09 Cellomics, Inc. Miniaturized cell array methods and apparatus for cell-based screening
JP3761676B2 (ja) 1997-07-11 2006-03-29 株式会社メニコン 細胞培養用容器
US6107085A (en) * 1997-07-11 2000-08-22 Corning Incorporated Self contained cell growth system
US6114165A (en) * 1997-07-23 2000-09-05 Cai; Xuejun Universal tissue culture flask
US6190913B1 (en) * 1997-08-12 2001-02-20 Vijay Singh Method for culturing cells using wave-induced agitation
US5823236A (en) * 1997-08-25 1998-10-20 Northrop Grumman Corporation Aerosol can puncturing machine
US6794184B1 (en) * 1998-01-19 2004-09-21 Ulrich Mohr Culturing device and method for culturing cells or tissue components
US6518035B1 (en) * 1998-06-02 2003-02-11 Rosetta Inpharmatics, Inc. Targeted methods of drug screening using co-culture methods
US6548299B1 (en) * 1999-11-12 2003-04-15 Mark J. Pykett Lymphoid tissue-specific cell production from hematopoietic progenitor cells in three-dimensional devices
US6455310B1 (en) * 1999-03-23 2002-09-24 Biocrystal Ltd. Cell culture apparatus and method for culturing cells
US6410309B1 (en) * 1999-03-23 2002-06-25 Biocrystal Ltd Cell culture apparatus and methods of use
DE60036385T2 (de) * 1999-06-21 2008-06-26 The General Hospital Corp., Boston Zellkultursysteme und verfahren für einrichtungen zur organunterstützung
TWI233449B (en) * 1999-07-01 2005-06-01 Ind Tech Res Inst High efficient cell-cultivating device
FR2803852B1 (fr) * 2000-01-17 2004-11-05 Farzin Sarem Dispositif de culture cellulaire et tissulaire a circulation de fluide de culture controlee
US6593136B1 (en) * 2000-03-20 2003-07-15 Geo-Centers, Inc. Culturing cells in a chamber in a stack of chambers
US6569675B2 (en) * 2000-06-16 2003-05-27 Corning Incorporated Cell cultivating flask and method for using the cell cultivating flask
EP1174497B1 (de) * 2000-07-19 2004-09-08 Technodop Ltd. (Société de Droit Irlandais) Kulturraum und Bioreaktor zur ausserkörperlichen Tierzellenkultur
JP4273643B2 (ja) * 2000-08-08 2009-06-03 味の素株式会社 好気性培養における培養装置及び消泡制御方法
DE10046175A1 (de) * 2000-09-19 2002-03-28 Augustinus Bader Verfahren und Vorrichtung zum Züchten und/oder Behandeln von Zellen
US20020039785A1 (en) * 2000-10-04 2002-04-04 Schroeder Kirk S. Cell-culture vessel
US6653124B1 (en) * 2000-11-10 2003-11-25 Cytoplex Biosciences Inc. Array-based microenvironment for cell culturing, cell monitoring and drug-target validation
US6555365B2 (en) * 2000-12-07 2003-04-29 Biocrystal, Ltd. Microincubator comprising a cell culture apparatus and a transparent heater
US6588586B2 (en) * 2000-12-08 2003-07-08 Biocrystal Ltd Mailer for cell culture device
US20020110905A1 (en) * 2001-02-15 2002-08-15 Emilio Barbera-Guillem Perfusion system for cultured cells
US6811752B2 (en) * 2001-05-15 2004-11-02 Biocrystal, Ltd. Device having microchambers and microfluidics
US6670171B2 (en) * 2001-07-09 2003-12-30 Wheaton Usa, Inc. Disposable vessel
US20040072347A1 (en) * 2001-07-27 2004-04-15 Gerold Schuler Generation of fully mature and stable dendritic cells from leukaphereses products for clinical applications
US6673595B2 (en) * 2001-08-27 2004-01-06 Biocrystal, Ltd Automated cell management system for growth and manipulation of cultured cells
WO2003060061A1 (en) * 2001-12-21 2003-07-24 Organogenesis Inc. Chamber with adjustable volume for cell culture and organ assist
US7033823B2 (en) * 2002-01-31 2006-04-25 Cesco Bioengineering, Inc. Cell-cultivating device
US7229820B2 (en) * 2002-06-13 2007-06-12 Wilson Wolf Manufacturing Corporation Apparatus and method for culturing and preserving tissue constructs
AU2003251874A1 (en) * 2002-07-12 2004-02-02 Dirk R. Albrecht Three dimensional cell patterned bioploymer scaffolds and method of making the same
US6841384B2 (en) * 2002-08-08 2005-01-11 Becton Dickinson Company Advanced roller bottle system for cell and tissue culturing
US20040029266A1 (en) * 2002-08-09 2004-02-12 Emilio Barbera-Guillem Cell and tissue culture device
AU2003275140A1 (en) * 2002-09-23 2004-04-08 Massachusetts Institute Of Technology Theree-dimensional construct for the design and fabrication of physiological fluidic networks
ES2295275T3 (es) * 2002-10-04 2008-04-16 Becton Dickinson And Company Frasco de cultivo.
WO2004044158A2 (en) * 2002-11-08 2004-05-27 The Johns Hopkins University Human embryonic stem cell cultures, and compositions and methods for growing same
AU2003291093A1 (en) * 2002-11-19 2004-06-15 The Board Of Trustees Of The University Of Illinois Multilayered microcultures
US7416884B2 (en) * 2003-02-26 2008-08-26 Georgia Tech Research Corporation Bioreactor and methods for tissue growth and conditioning
CN1788080A (zh) * 2003-05-14 2006-06-14 株式会社日本组织工程 细胞培养方法及培养的组织
US20050032208A1 (en) * 2003-06-18 2005-02-10 Oh Steve Kah Weng Materials and methods to produce stem cells
CN101120083B (zh) * 2003-10-08 2013-03-27 威尔森沃尔夫制造公司 利用透气性材料进行细胞培养的方法及装置
US7097690B2 (en) * 2003-10-10 2006-08-29 Scimed Life Systems, Inc. Apparatus and method for removing gasses from a liquid
EP2267111A3 (de) * 2003-11-10 2012-04-25 Wilson Wolf Manufacturing Corporation Vorrichtung mit Unterteilungen für Zellkulturen, Zellverarbeitung und Probendialyse
US7078228B2 (en) * 2003-12-31 2006-07-18 Corning Incorporated Cell cultivating flask
NZ548623A (en) * 2004-01-02 2010-04-30 Advanced Cell Tech Inc Novel culture systems for ex vivo development of stem cells in telolecithal or eutelolecithal eggs
CN101061213B (zh) * 2004-05-19 2012-12-19 麻省理工学院 灌注的三维细胞/组织疾病模型
US7700333B2 (en) * 2004-07-26 2010-04-20 Agency For Science Technology & Research Immobilization of cells in a matrix formed by biocompatible charged polymers under laminar flow conditions
US7022518B1 (en) * 2005-01-31 2006-04-04 Glen Feye Apparatus and method for co-culturing of cells
US7745209B2 (en) * 2005-07-26 2010-06-29 Corning Incorporated Multilayered cell culture apparatus
US7820431B2 (en) * 2005-12-30 2010-10-26 Corning Incorporated Device for trapping extraneous gas

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EP2118259B1 (de) 2011-04-20
JP2010518879A (ja) 2010-06-03
US7897379B2 (en) 2011-03-01
EP2118259A1 (de) 2009-11-18
DE602008006361D1 (de) 2011-06-01
JP5088756B2 (ja) 2012-12-05
US20080206857A1 (en) 2008-08-28

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