ATE507240T1 - Materialien und verfahren für wachstumsfaktorbindende konstrukte - Google Patents
Materialien und verfahren für wachstumsfaktorbindende konstrukteInfo
- Publication number
- ATE507240T1 ATE507240T1 AT05725099T AT05725099T ATE507240T1 AT E507240 T1 ATE507240 T1 AT E507240T1 AT 05725099 T AT05725099 T AT 05725099T AT 05725099 T AT05725099 T AT 05725099T AT E507240 T1 ATE507240 T1 AT E507240T1
- Authority
- AT
- Austria
- Prior art keywords
- growth factor
- methods
- materials
- binding constructs
- factor binding
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2863—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Cell Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Oncology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Ceramic Products (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US55090704P | 2004-03-05 | 2004-03-05 | |
| PCT/US2005/007741 WO2005087808A2 (en) | 2004-03-05 | 2005-03-07 | Growth factor binding constructs materials and methods |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE507240T1 true ATE507240T1 (de) | 2011-05-15 |
Family
ID=34962227
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT05725099T ATE507240T1 (de) | 2004-03-05 | 2005-03-07 | Materialien und verfahren für wachstumsfaktorbindende konstrukte |
Country Status (6)
| Country | Link |
|---|---|
| US (3) | US7422741B2 (de) |
| EP (1) | EP1732947B1 (de) |
| AT (1) | ATE507240T1 (de) |
| AU (1) | AU2005222384A1 (de) |
| DE (1) | DE602005027673D1 (de) |
| WO (1) | WO2005087808A2 (de) |
Families Citing this family (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2435503C (en) | 2001-01-19 | 2011-02-22 | Ludwig Institute For Cancer Research | Flt4(vegfr-3) as a target for tumor imaging and anti-tumor therapy |
| DE60236646D1 (de) | 2001-04-13 | 2010-07-22 | Human Genome Sciences Inc | Anti-VEGF-2 Antikörper |
| ATE507240T1 (de) * | 2004-03-05 | 2011-05-15 | Vegenics Pty Ltd | Materialien und verfahren für wachstumsfaktorbindende konstrukte |
| WO2005087177A2 (en) * | 2004-03-05 | 2005-09-22 | Ludwig Institute For Cancer Research | Chimeric anti-vegf-d antibodies and humanized anti-vegf-d antibodies and methods of using same |
| US20060110364A1 (en) * | 2004-08-20 | 2006-05-25 | Ludwig Institute For Cancer Research | Vector-mediated delivery of polynucleotides encoding soluble VEGF receptors |
| HUE034109T2 (en) | 2005-03-25 | 2018-01-29 | Regeneron Pharma | VEGF antagonist formulations |
| KR101246504B1 (ko) * | 2005-06-17 | 2013-03-26 | 임클론 엘엘씨 | 항-PDGFRα 항체 |
| DK2548578T3 (da) | 2006-05-17 | 2014-10-06 | Ludwig Inst Cancer Res | Målretning af VEGF-B-regulering af fedtsyretransportører til modulering af humane sygdomme |
| SI2944306T1 (sl) | 2006-06-16 | 2021-04-30 | Regeneron Pharmaceuticals, Inc. | Formulacije antagonista VEGF, primerne za intravitrealno dajanje |
| EP2125895B1 (de) * | 2007-02-02 | 2015-04-08 | Vegenics Pty Ltd | Vegf-rezeptorantagonisten zur behandlung von allommunität bei organtransplantationen und atherosklerose |
| TWI436775B (zh) * | 2007-08-24 | 2014-05-11 | Oncotherapy Science Inc | 以抗原胜肽合併化療藥劑治療胰臟癌 |
| DK2215247T3 (en) * | 2007-11-13 | 2014-12-08 | Scripps Research Inst | Preparation of a fusion of cytotoxic antibody toxin into eukaryotic algae |
| WO2009149205A2 (en) * | 2008-06-03 | 2009-12-10 | Neurotech Usa, Inc. | Cell lines that secrete soluble vegf receptors and uses thereof |
| WO2011075185A1 (en) | 2009-12-18 | 2011-06-23 | Oligasis | Targeted drug phosphorylcholine polymer conjugates |
| WO2011106697A1 (en) | 2010-02-25 | 2011-09-01 | Schepens Eye Research Institute | Therapeutic compositions for the treatment of dry eye disease |
| CN103533950A (zh) | 2011-01-13 | 2014-01-22 | 瑞泽恩制药公司 | Vegf拮抗剂在治疗血管生成眼病中的用途 |
| CA2862270A1 (en) * | 2011-12-29 | 2013-07-04 | Baylor Research Institute | Biomarkers of kawasaki disease |
| EP2911681A1 (de) | 2012-10-26 | 2015-09-02 | Institut National de la Santé et de la Recherche Médicale (INSERM) | Lyve-1-antagonisten zur vorbeugung oder behandlung eines pathologischen leidens in zusammenhang mit lymphangiogenese |
| CN103113468B (zh) * | 2013-01-17 | 2014-05-21 | 中国人民解放军军事医学科学院基础医学研究所 | 一种抗肿瘤蛋白质 |
| MY199344A (en) * | 2013-02-18 | 2023-10-24 | Vegenics Pty Ltd | Ligand binding molecules and uses thereof |
| US10274503B2 (en) | 2013-05-08 | 2019-04-30 | Vegenics Pty Limited | Methods of using VEGF-C biomarkers for age-related macular degeneration (AMD) diagnosis |
| US8895611B1 (en) | 2013-07-17 | 2014-11-25 | King Fahd University Of Petroleum And Minerals | Cytotoxic compounds for treating cancer |
| KR102060187B1 (ko) * | 2013-07-19 | 2019-12-27 | 삼성전자주식회사 | Vegf-c, vegf-d 및/또는 안지오포이에틴-2를 동시에 저해하는 융합 폴리펩타이드 및 이의 용도 |
| WO2015035342A2 (en) | 2013-09-08 | 2015-03-12 | Oligasis Llc | Factor viii zwitterionic polymer conjugates |
| KR102213653B1 (ko) * | 2014-02-21 | 2021-02-09 | 베지닉스 피티와이 리미티드 | 리간드 결합 분자 및 이의 용도 |
| WO2015196072A2 (en) | 2014-06-19 | 2015-12-23 | Whitehead Institute For Biomedical Research | Uses of kinase inhibitors for inducing and maintaining pluripotency |
| US9840553B2 (en) | 2014-06-28 | 2017-12-12 | Kodiak Sciences Inc. | Dual PDGF/VEGF antagonists |
| MX379491B (es) * | 2014-06-28 | 2025-03-10 | Kodiak Sciences Inc | Antagonistas duales de factor de crecimiento derivado de plaquetas (pdgf)/factor de crecimiento endotelial vascular (vegf) |
| KR20210013299A (ko) | 2014-10-17 | 2021-02-03 | 코디악 사이언시스 인코포레이티드 | 부티릴콜린에스테라제 양성이온성 중합체 컨쥬게이트 |
| KR20250057128A (ko) | 2015-12-30 | 2025-04-28 | 코디악 사이언시스 인코포레이티드 | 항체 및 이의 접합체 |
| AU2016413999B2 (en) * | 2016-07-05 | 2020-05-14 | Ibentrus, Inc. | Cancer treatment composition for inhibiting tumor angiogenesis, containing VEGF deep blocker, and preparation method therefor |
| KR20190050807A (ko) | 2016-09-09 | 2019-05-13 | 메르크 파텐트 게엠베하 | 고체 약학적 투여 형태의 제조 방법 |
| AU2018375398C1 (en) | 2017-11-30 | 2026-01-15 | Regeneron Pharmaceuticals, Inc. | Use of a VEGF antagonist to treat angiogenic eye disorders |
| US12071476B2 (en) | 2018-03-02 | 2024-08-27 | Kodiak Sciences Inc. | IL-6 antibodies and fusion constructs and conjugates thereof |
| AU2020364071A1 (en) | 2019-10-10 | 2022-05-26 | Kodiak Sciences Inc. | Methods of treating an eye disorder |
| MX2022013812A (es) | 2020-05-08 | 2022-12-15 | Regeneron Pharma | Trampas y mini-trampas de vegf y metodos para el tratamiento de trastornos oculares y cancer. |
| MX2023004839A (es) * | 2020-10-30 | 2023-06-29 | Eluminex Biosciences Suzhou Ltd | Inhibidores de factores angiogenicos. |
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| US3773919A (en) | 1969-10-23 | 1973-11-20 | Du Pont | Polylactide-drug mixtures |
| US3691016A (en) | 1970-04-17 | 1972-09-12 | Monsanto Co | Process for the preparation of insoluble enzymes |
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| US4195128A (en) | 1976-05-03 | 1980-03-25 | Bayer Aktiengesellschaft | Polymeric carrier bound ligands |
| US4330440A (en) | 1977-02-08 | 1982-05-18 | Development Finance Corporation Of New Zealand | Activated matrix and method of activation |
| CA1093991A (en) | 1977-02-17 | 1981-01-20 | Hideo Hirohara | Enzyme immobilization with pullulan gel |
| US4229537A (en) | 1978-02-09 | 1980-10-21 | New York University | Preparation of trichloro-s-triazine activated supports for coupling ligands |
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| US7611711B2 (en) * | 2001-01-17 | 2009-11-03 | Vegenics Limited | VEGFR-3 inhibitor materials and methods |
| CA2435503C (en) * | 2001-01-19 | 2011-02-22 | Ludwig Institute For Cancer Research | Flt4(vegfr-3) as a target for tumor imaging and anti-tumor therapy |
| TWI320038B (en) * | 2001-03-30 | 2010-02-01 | An 1,4-dihydropiridine derivatives pharmacologically with adrenoceptor and calcium channel blocking activities | |
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| US20030113324A1 (en) | 2001-10-01 | 2003-06-19 | Kari Alitalo | Neuropilin/VEGF-C/VEGFR-3 materials and methods |
| WO2005087812A1 (en) * | 2004-03-05 | 2005-09-22 | Ludwig Institute For Cancer Research | Multivalent antibody materials and methods for vegf/pdgf family of growth factors |
| ATE507240T1 (de) * | 2004-03-05 | 2011-05-15 | Vegenics Pty Ltd | Materialien und verfahren für wachstumsfaktorbindende konstrukte |
| KR100883430B1 (ko) * | 2007-06-13 | 2009-02-12 | 한국생명공학연구원 | 혈관내피성장인자 수용체를 중화하는 인간 단클론항체 및그 용도 |
-
2005
- 2005-03-07 AT AT05725099T patent/ATE507240T1/de not_active IP Right Cessation
- 2005-03-07 DE DE602005027673T patent/DE602005027673D1/de active Active
- 2005-03-07 US US11/075,047 patent/US7422741B2/en not_active Expired - Fee Related
- 2005-03-07 EP EP05725099A patent/EP1732947B1/de not_active Expired - Lifetime
- 2005-03-07 AU AU2005222384A patent/AU2005222384A1/en not_active Abandoned
- 2005-03-07 WO PCT/US2005/007741 patent/WO2005087808A2/en not_active Ceased
-
2008
- 2008-07-28 US US12/180,990 patent/US7855178B2/en not_active Expired - Fee Related
-
2010
- 2010-12-17 US US12/971,865 patent/US20110243912A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AU2005222384A1 (en) | 2005-09-22 |
| US20110243912A1 (en) | 2011-10-06 |
| US20090155268A1 (en) | 2009-06-18 |
| WO2005087808A2 (en) | 2005-09-22 |
| EP1732947A2 (de) | 2006-12-20 |
| US7855178B2 (en) | 2010-12-21 |
| US7422741B2 (en) | 2008-09-09 |
| EP1732947B1 (de) | 2011-04-27 |
| DE602005027673D1 (de) | 2011-06-09 |
| WO2005087808A3 (en) | 2005-12-01 |
| US20060030000A1 (en) | 2006-02-09 |
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