ATE507242T1 - Wirtszellenspezifische bindungsmoleküle, die dazu in der lage sind, viren zu neutralisieren, und anwendungen davon - Google Patents
Wirtszellenspezifische bindungsmoleküle, die dazu in der lage sind, viren zu neutralisieren, und anwendungen davonInfo
- Publication number
- ATE507242T1 ATE507242T1 AT06755161T AT06755161T ATE507242T1 AT E507242 T1 ATE507242 T1 AT E507242T1 AT 06755161 T AT06755161 T AT 06755161T AT 06755161 T AT06755161 T AT 06755161T AT E507242 T1 ATE507242 T1 AT E507242T1
- Authority
- AT
- Austria
- Prior art keywords
- binding molecules
- host cell
- applications
- specific binding
- human binding
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/10—RNA viruses
- C07K16/116—Togaviridae (F); Matonaviridae (F); Flaviviridae (F)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Virology (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Communicable Diseases (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EPPCT/EP05/52160 | 2005-05-12 | ||
| EPPCT/EP05/52648 | 2005-06-08 | ||
| EPPCT/EP05/52946 | 2005-06-23 | ||
| EPPCT/EP05/54002 | 2005-08-15 | ||
| PCT/EP2006/062250 WO2006120230A2 (en) | 2005-05-12 | 2006-05-11 | Host cell specific binding molecules capable of neutralizing viruses and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE507242T1 true ATE507242T1 (de) | 2011-05-15 |
Family
ID=37396920
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT06755161T ATE507242T1 (de) | 2005-05-12 | 2006-05-11 | Wirtszellenspezifische bindungsmoleküle, die dazu in der lage sind, viren zu neutralisieren, und anwendungen davon |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US8052974B2 (de) |
| EP (1) | EP1879921B1 (de) |
| AT (1) | ATE507242T1 (de) |
| AU (1) | AU2006245734C1 (de) |
| CA (1) | CA2608058C (de) |
| IL (1) | IL187321A (de) |
| WO (1) | WO2006120230A2 (de) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2314629B2 (de) | 2002-07-18 | 2022-11-16 | Merus N.V. | Rekombinante Herstellung von Mischungen aus Aantikörpern |
| USRE47770E1 (en) | 2002-07-18 | 2019-12-17 | Merus N.V. | Recombinant production of mixtures of antibodies |
| US20100069614A1 (en) | 2008-06-27 | 2010-03-18 | Merus B.V. | Antibody producing non-human mammals |
| WO2004106375A1 (en) | 2003-05-30 | 2004-12-09 | Merus Biopharmaceuticals B.V. I.O. | Fab library for the preparation of anti vegf and anti rabies virus fabs |
| WO2005118644A2 (en) | 2004-05-27 | 2005-12-15 | Crucell Holland B.V. | Binding molecules capable of neutralizing rabies virus and uses thereof |
| WO2006120230A2 (en) | 2005-05-12 | 2006-11-16 | Crucell Holland B.V. | Host cell specific binding molecules capable of neutralizing viruses and uses thereof |
| EP2059532B1 (de) | 2006-09-07 | 2012-12-26 | Crucell Holland B.V. | Humane bindungsmoleküle, die in der lage sind, das grippevirus h5n1 zu neutralisieren, und anwendungen davon |
| ES2611479T3 (es) | 2010-06-16 | 2017-05-09 | University Of Pittsburgh- Of The Commonwealth System Of Higher Education | Anticuerpos contra endoplasmina y su uso |
| CA2791109C (en) | 2011-09-26 | 2021-02-16 | Merus B.V. | Generation of binding molecules |
| DK2838918T3 (da) | 2012-04-20 | 2019-08-12 | Merus Nv | Fremgangsmåder og midler til fremstilling af heterodimere ig-lignende molekyler |
| KR101815265B1 (ko) * | 2013-06-20 | 2018-01-04 | 한올바이오파마주식회사 | FcRn 특이적 인간 항체 및 이를 포함하는 자가면역 질환 치료용 조성물 |
| CA2938590C (en) | 2014-02-11 | 2023-10-17 | Visterra, Inc. | Antibody molecules to dengue virus and uses thereof |
| WO2016138312A2 (en) * | 2015-02-25 | 2016-09-01 | Vanderbilt University | Antibody-mediated neutralization of marburg virus |
| JP6811723B2 (ja) * | 2015-04-17 | 2021-01-13 | アイジーエム バイオサイエンシズ インコーポレイテッド | 多価ヒト免疫不全ウイルス抗原結合分子およびその使用方法 |
| CN107921127B (zh) * | 2015-05-22 | 2022-04-08 | 纪念斯隆-凯特琳癌症中心 | 对于prame肽具有特异性的t细胞受体样抗体 |
| JP7155009B2 (ja) | 2016-03-25 | 2022-10-18 | ビステラ, インコーポレイテッド | デングウイルスに対する抗体分子の製剤 |
| BR112020003622A2 (pt) | 2017-08-21 | 2020-09-01 | Adagene Inc. | cadeia pesada de anticorpo, anticorpo, bibliotecas, kit, método de preparo de uma biblioteca, método de produção de uma biblioteca de anticorpos, fago, método de geração de um anticorpo biespecífico e anticorpo biespecífico |
| WO2019036856A1 (en) * | 2017-08-21 | 2019-02-28 | Adagene Inc. | DYNAMIC BANKS OF LIGHT CHAIN OF HUMAN ANTIBODY |
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| NZ207394A (en) | 1983-03-08 | 1987-03-06 | Commw Serum Lab Commission | Detecting or determining sequence of amino acids |
| US4816567A (en) * | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| US6184024B1 (en) * | 1988-07-14 | 2001-02-06 | The United States Of America As Represented By The Department Of Health And Human Services | Chimeric and/or growth-restricted flaviviruses |
| MY109299A (en) * | 1990-08-15 | 1996-12-31 | Virogenetics Corp | Recombinant pox virus encoding flaviviral structural proteins |
| US5514375A (en) * | 1990-08-15 | 1996-05-07 | Virogenetics Corporation | Flavivirus recombinant poxvirus vaccine |
| US5494671A (en) * | 1990-08-27 | 1996-02-27 | The United States Of America As Represented By The Department Of Health And Human Services | C-terminally truncated dengue and Japanese encephalitis virus envelope proteins |
| DE69230316T2 (de) | 1991-09-19 | 2000-07-13 | Us Health | Chimäre und/oder wachstumsgehemmte flaviviren |
| NL9101953A (nl) | 1991-11-21 | 1993-06-16 | Seed Capital Investments | Testinrichting omvattende een plaat met een veelvoud van putjes met een bijbehorende doseerinrichting, alsmede een kit die deze inrichtingen omvat en toepassing van de inrichtingen. |
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| HU219503B (hu) | 1994-07-08 | 2001-04-28 | Baxter Aktiengesellschaft | Javított vakcina TBE-vírusfertőzés elleni immunizálásra, valamint eljárás az előállítására |
| US6265150B1 (en) | 1995-06-07 | 2001-07-24 | Becton Dickinson & Company | Phage antibodies |
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| JP2001512560A (ja) | 1996-10-08 | 2001-08-21 | ユー―ビスイス ベスローテン フェンノートシャップ | 標的に対し特異的な親和性を有するペプチドおよびタンパク質の選択のための方法および手段 |
| CA2282790C (en) | 1997-02-28 | 2011-04-19 | St. Louis University | Chimeric flavivirus vaccines |
| WO1999026653A1 (en) | 1997-11-20 | 1999-06-03 | United States Army Medical Research And Material Command | Dna vaccines against tick-borne flaviviruses |
| US7417136B1 (en) | 1998-06-04 | 2008-08-26 | The United States Of America As Represented By The Secretary, Department Of Health And Human Services, Centers For Disease Control And Prevention | Nucleic acid vaccines for prevention of flavivirus infection |
| EP1107961A4 (de) | 1998-08-25 | 2002-01-30 | Univ Yale | Hemmung und behandlung des hepatitis b-virus und flavivirus durch helioxanthin und analoga davon |
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| AU774045B2 (en) | 1998-09-02 | 2004-06-17 | Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The | Dengue viruses that are replication defective in mosquitos for use as vaccines |
| US6685948B1 (en) * | 1998-09-02 | 2004-02-03 | The United States Of America As Represented By The Department Of Health And Human Services | Replication-defective dengue viruses that are replication-defective in mosquitoes for use as vaccines |
| CN100457914C (zh) | 1999-04-15 | 2009-02-04 | 荷兰克鲁塞尔公司 | 用编码腺病毒e1蛋白的序列在人体细胞中生产重组蛋白 |
| US6432411B1 (en) | 1999-07-13 | 2002-08-13 | Hawaii Biotechnology Group | Recombinant envelope vaccine against flavivirus infection |
| EP1103610A1 (de) | 1999-11-26 | 2001-05-30 | Introgene B.V. | Impfstoffherstellung von immortalisierten Säugetierzellinien |
| WO2004042042A1 (en) | 2002-11-08 | 2004-05-21 | Crucell Holland B.V. | Vaccines against west nile virus |
| US7425437B2 (en) | 1999-11-26 | 2008-09-16 | Crucell Holland B.V. | Vaccines against West Nile Virus |
| AU1813901A (en) | 1999-12-01 | 2001-06-12 | Oravax, Inc | Chimeric flavivirus vaccines |
| CA2941182A1 (en) | 2000-02-16 | 2001-08-23 | The Government Of The United States Of America As Represented By The Secretary, Department Of Health And Human Services | Avirulent, immunogenic flavivirus chimeras |
| CN1427722A (zh) | 2000-02-18 | 2003-07-02 | 希拉生物化学股份有限公司 | 用核苷类似物治疗或预防黄病毒感染的方法 |
| MXPA02012867A (es) * | 2000-06-29 | 2003-09-05 | Abbott Lab | Anticuerpos de especificidad doble y metodos para la elaboracion y el uso de los mismos. |
| US6946125B2 (en) * | 2000-08-23 | 2005-09-20 | The New York Hospital Medical Center Of Queens | Methods of treating West Nile virus infection |
| CA2440593A1 (en) | 2001-03-12 | 2002-09-19 | Yale University | Compositions and methods comprising west nile virus polypeptides |
| DK1402025T3 (da) | 2001-06-15 | 2006-06-06 | Crucell Holland Bv | Kimære fager |
| AU2002365244B2 (en) | 2001-07-27 | 2007-12-06 | Zoetis Services Llc | West nile vaccine |
| AU2003213022A1 (en) | 2002-02-11 | 2003-09-22 | Alexion Pharmaceuticals, Inc. | Immunotherapeutics for biodefense |
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| CN100558895C (zh) | 2003-07-18 | 2009-11-11 | 持田制药株式会社 | 抗血小板膜糖蛋白vi单克隆抗体 |
| SG128680A1 (en) | 2003-07-22 | 2007-01-30 | Crucell Holland Bv | Binding molecules against sars-coronavirus and uses thereof |
| ES2378767T3 (es) | 2003-12-23 | 2012-04-17 | Crucell Holland B.V. | Molécula de unión humana contra CD1a |
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| WO2005111623A1 (en) | 2004-05-17 | 2005-11-24 | Crucell Holland B.V. | Methods for diagnosis of acute myeloid leukemia |
| WO2005118644A2 (en) | 2004-05-27 | 2005-12-15 | Crucell Holland B.V. | Binding molecules capable of neutralizing rabies virus and uses thereof |
| WO2005123774A2 (en) | 2004-06-15 | 2005-12-29 | Erol Fikrig | Antibodies to west nile virus polypeptides |
| US7527973B2 (en) | 2004-06-21 | 2009-05-05 | Washington University | Antibodies against West Nile Virus and therapeutic and prophylactic uses thereof |
| CA2579142A1 (en) | 2004-09-13 | 2006-03-23 | Macrogenics, Inc. | Humanized antibodies against west nile virus and therapeutic and prophylactic uses thereof |
| WO2006040322A1 (en) | 2004-10-12 | 2006-04-20 | Crucell Holland B.V. | Binding molecules for treatment and detection of cancer |
| WO2007011392A2 (en) | 2004-10-14 | 2007-01-25 | Washington University | Crystal structure of domain 111 of west nile virus envelope protein-fab fragment of neutralizing antibody complex |
| KR101255861B1 (ko) | 2004-11-11 | 2013-04-17 | 크루셀 홀란드 비.브이. | 사스-코로나바이러스에 대한 조성물 및 그것의 용도 |
| WO2006056006A1 (en) | 2004-11-23 | 2006-06-01 | The University Of Queensland | Equine west nile virus immunotherapy |
| CA2591665C (en) | 2004-12-20 | 2015-05-05 | Crucell Holland B.V. | Binding molecules capable of neutralizing west nile virus and uses thereof |
| WO2006120230A2 (en) | 2005-05-12 | 2006-11-16 | Crucell Holland B.V. | Host cell specific binding molecules capable of neutralizing viruses and uses thereof |
| EP1893645A1 (de) | 2005-06-23 | 2008-03-05 | Crucell Holland B.V. | Optimierung von antikörpern gegen das west-nile-virus |
| CA2622603C (en) | 2005-09-15 | 2014-06-17 | Crucell Holland B.V. | Method for preparing immunoglobulin libraries |
| CN103351435B (zh) | 2006-06-06 | 2015-08-19 | 克鲁塞尔荷兰公司 | 具有杀灭葡萄球菌活性的人结合分子及其应用 |
| MX2008014978A (es) | 2006-06-06 | 2008-12-09 | Crucell Holland Bv | Moleculas de union humanas que tienen actividad exterminadora contra enterococos y staphylococcus aureus y usos de las mismas. |
| EP2059532B1 (de) | 2006-09-07 | 2012-12-26 | Crucell Holland B.V. | Humane bindungsmoleküle, die in der lage sind, das grippevirus h5n1 zu neutralisieren, und anwendungen davon |
-
2006
- 2006-05-11 WO PCT/EP2006/062250 patent/WO2006120230A2/en not_active Ceased
- 2006-05-11 EP EP06755161A patent/EP1879921B1/de not_active Expired - Lifetime
- 2006-05-11 AU AU2006245734A patent/AU2006245734C1/en not_active Ceased
- 2006-05-11 CA CA2608058A patent/CA2608058C/en not_active Expired - Fee Related
- 2006-05-11 US US11/919,265 patent/US8052974B2/en not_active Expired - Fee Related
- 2006-05-11 AT AT06755161T patent/ATE507242T1/de not_active IP Right Cessation
-
2007
- 2007-11-12 IL IL187321A patent/IL187321A/en active IP Right Grant
-
2011
- 2011-08-25 US US13/199,348 patent/US8911738B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CA2608058A1 (en) | 2006-11-16 |
| EP1879921B1 (de) | 2011-04-27 |
| WO2006120230A3 (en) | 2007-06-21 |
| US20120076794A1 (en) | 2012-03-29 |
| US20100303801A1 (en) | 2010-12-02 |
| CA2608058C (en) | 2013-09-10 |
| US8052974B2 (en) | 2011-11-08 |
| IL187321A (en) | 2013-06-27 |
| AU2006245734A1 (en) | 2006-11-16 |
| WO2006120230A2 (en) | 2006-11-16 |
| IL187321A0 (en) | 2008-04-13 |
| EP1879921A2 (de) | 2008-01-23 |
| US8911738B2 (en) | 2014-12-16 |
| AU2006245734C1 (en) | 2012-05-24 |
| AU2006245734B2 (en) | 2011-12-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |