ATE509117T1 - Herstellungsverfahren für hyaluronsäure oder ihre derivate - Google Patents
Herstellungsverfahren für hyaluronsäure oder ihre derivateInfo
- Publication number
- ATE509117T1 ATE509117T1 AT02705196T AT02705196T ATE509117T1 AT E509117 T1 ATE509117 T1 AT E509117T1 AT 02705196 T AT02705196 T AT 02705196T AT 02705196 T AT02705196 T AT 02705196T AT E509117 T1 ATE509117 T1 AT E509117T1
- Authority
- AT
- Austria
- Prior art keywords
- hyaluronic acid
- derivatives
- production process
- derivative
- producing
- Prior art date
Links
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 title abstract 5
- 229920002674 hyaluronan Polymers 0.000 title abstract 3
- 229960003160 hyaluronic acid Drugs 0.000 title abstract 3
- 238000004519 manufacturing process Methods 0.000 title abstract 3
- 125000003504 2-oxazolinyl group Chemical class O1C(=NCC1)* 0.000 abstract 1
- 241000561734 Celosia cristata Species 0.000 abstract 1
- 108010003272 Hyaluronate lyase Proteins 0.000 abstract 1
- 102000001974 Hyaluronidases Human genes 0.000 abstract 1
- 239000012295 chemical reaction liquid Substances 0.000 abstract 1
- 210000001520 comb Anatomy 0.000 abstract 1
- 238000000605 extraction Methods 0.000 abstract 1
- 238000000855 fermentation Methods 0.000 abstract 1
- 230000004151 fermentation Effects 0.000 abstract 1
- 229960002773 hyaluronidase Drugs 0.000 abstract 1
- 238000002955 isolation Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 238000000746 purification Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/26—Preparation of nitrogen-containing carbohydrates
Landscapes
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Purification Treatments By Anaerobic Or Anaerobic And Aerobic Bacteria Or Animals (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2001071873 | 2001-03-14 | ||
| PCT/JP2002/002431 WO2002072860A1 (en) | 2001-03-14 | 2002-03-14 | Process for producing hyaluronic acid or its derivative |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE509117T1 true ATE509117T1 (de) | 2011-05-15 |
Family
ID=18929540
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02705196T ATE509117T1 (de) | 2001-03-14 | 2002-03-14 | Herstellungsverfahren für hyaluronsäure oder ihre derivate |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US7105320B2 (de) |
| EP (1) | EP1371733B1 (de) |
| JP (1) | JP4036755B2 (de) |
| AT (1) | ATE509117T1 (de) |
| WO (1) | WO2002072860A1 (de) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2599843C (en) * | 2005-03-01 | 2013-08-27 | Simon Fraser University | Selective glycosidase inhibitors, methods of making inhibitors, and uses thereof |
| US8334310B2 (en) | 2006-08-31 | 2012-12-18 | Simon Fraser University | Selective glycosidase inhibitors and uses thereof |
| WO2008111526A1 (ja) * | 2007-03-09 | 2008-09-18 | Seikagaku Corporation | 糖オキサゾリン誘導体の製造方法 |
| TWI572609B (zh) | 2010-12-23 | 2017-03-01 | 默沙東藥廠 | 選擇性醣苷酶抑制劑及其用途 |
| EP2691407B1 (de) | 2011-03-31 | 2017-02-22 | Alectos Therapeutics Inc. | Selektive glycosidasehemmer und ihre verwendung |
| US9701693B2 (en) | 2011-06-27 | 2017-07-11 | Alectos Therapeutics Inc. | Selective glycosidase inhibitors and uses thereof |
| EP2890675A4 (de) | 2012-08-31 | 2016-01-13 | Alectos Therapeutics Inc | Glycosidasehemmer und verwendungen davon |
| WO2014032185A1 (en) | 2012-08-31 | 2014-03-06 | Alectos Therapeutics Inc. | Glycosidase inhibitors and uses thereof |
| RU2672873C2 (ru) | 2012-10-31 | 2018-11-20 | Алектос Терапьютикс Инк. | Ингибиторы гликозидаз и их применения |
| CN109912668B (zh) * | 2019-01-17 | 2022-06-14 | 中国科学院昆明植物研究所 | 岩藻糖化硫酸软骨素三糖的制备方法、中间体和用途 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH093088A (ja) * | 1995-06-19 | 1997-01-07 | Shin Etsu Chem Co Ltd | アミノ二糖及びキチン又はその類似多糖類の製造方法 |
-
2002
- 2002-03-14 AT AT02705196T patent/ATE509117T1/de not_active IP Right Cessation
- 2002-03-14 WO PCT/JP2002/002431 patent/WO2002072860A1/ja not_active Ceased
- 2002-03-14 EP EP02705196A patent/EP1371733B1/de not_active Expired - Lifetime
- 2002-03-14 US US10/469,984 patent/US7105320B2/en not_active Expired - Fee Related
- 2002-03-14 JP JP2002571910A patent/JP4036755B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP1371733A1 (de) | 2003-12-17 |
| EP1371733B1 (de) | 2011-05-11 |
| US7105320B2 (en) | 2006-09-12 |
| JP4036755B2 (ja) | 2008-01-23 |
| WO2002072860A1 (en) | 2002-09-19 |
| US20040132142A1 (en) | 2004-07-08 |
| JPWO2002072860A1 (ja) | 2004-07-02 |
| EP1371733A4 (de) | 2009-09-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |