ATE509268T1 - Nachweis von tumorstammzellen und tumorzellen in epithel-mesenchym-transition in körperflüssigkeiten von krebspatienten - Google Patents

Nachweis von tumorstammzellen und tumorzellen in epithel-mesenchym-transition in körperflüssigkeiten von krebspatienten

Info

Publication number
ATE509268T1
ATE509268T1 AT08802299T AT08802299T ATE509268T1 AT E509268 T1 ATE509268 T1 AT E509268T1 AT 08802299 T AT08802299 T AT 08802299T AT 08802299 T AT08802299 T AT 08802299T AT E509268 T1 ATE509268 T1 AT E509268T1
Authority
AT
Austria
Prior art keywords
cells
tumor
epithelial
detection
sample
Prior art date
Application number
AT08802299T
Other languages
English (en)
Inventor
Siegfried Hauch
Winfried Albert
Original Assignee
Adnagen Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Adnagen Ag filed Critical Adnagen Ag
Application granted granted Critical
Publication of ATE509268T1 publication Critical patent/ATE509268T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54393—Improving reaction conditions or stability, e.g. by coating or irradiation of surface, by reduction of non-specific binding, by promotion of specific binding
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/34—Purifying; Cleaning
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/30—Organic components
    • C12N2500/35—Polyols, e.g. glycerin, inositol

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT08802299T 2007-09-17 2008-09-17 Nachweis von tumorstammzellen und tumorzellen in epithel-mesenchym-transition in körperflüssigkeiten von krebspatienten ATE509268T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP07018205A EP2037265A1 (de) 2007-09-17 2007-09-17 Verfahren zur Isolierung und/oder Anreicherung von Zellen an festen Phasen
EP08008770A EP2037266A1 (de) 2007-09-17 2008-05-09 Verfahren zur Isolierung und oder Anreicherung von Zellen an festen Phasen
PCT/EP2008/007775 WO2009036968A1 (en) 2007-09-17 2008-09-17 Detection of tumor stem cells and tumor cells in epithelial-mesenchymal transition in body fluids of cancer patients

Publications (1)

Publication Number Publication Date
ATE509268T1 true ATE509268T1 (de) 2011-05-15

Family

ID=38659627

Family Applications (2)

Application Number Title Priority Date Filing Date
AT08802298T ATE533049T1 (de) 2007-09-17 2008-09-17 Festphasen-zellisolierungs- und/oder - anreicherungsverfahren
AT08802299T ATE509268T1 (de) 2007-09-17 2008-09-17 Nachweis von tumorstammzellen und tumorzellen in epithel-mesenchym-transition in körperflüssigkeiten von krebspatienten

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT08802298T ATE533049T1 (de) 2007-09-17 2008-09-17 Festphasen-zellisolierungs- und/oder - anreicherungsverfahren

Country Status (5)

Country Link
US (4) US8557528B2 (de)
EP (4) EP2037265A1 (de)
AT (2) ATE533049T1 (de)
ES (2) ES2366269T3 (de)
WO (2) WO2009036968A1 (de)

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WO2011093927A1 (en) * 2010-01-27 2011-08-04 Duke University Biomarkers for circulating tumor cells
EP2726870B1 (de) 2011-06-29 2018-10-03 Academia Sinica Erfassung, reinigung und freisetzung eines biologischen stoffes anahnd einer oberflächenbeschichtung
EP2737317A2 (de) * 2011-07-28 2014-06-04 The Trustees Of The University Of Pennsylvania Verfahren zur krebsdiagnose durch tumorzellencharakterisierung mithilfe pleuraler oder seröser flüssigkeiten
CN103998394B (zh) 2011-08-01 2016-08-17 德诺弗科学公司 细胞捕获系统和使用方法
US10466160B2 (en) 2011-08-01 2019-11-05 Celsee Diagnostics, Inc. System and method for retrieving and analyzing particles
US9404864B2 (en) 2013-03-13 2016-08-02 Denovo Sciences, Inc. System for imaging captured cells
KR101933618B1 (ko) 2011-11-29 2018-12-31 삼성전자주식회사 표적 물질 검출 및 분리 장치, 및 이를 이용한 표적 물질 검출 및 분리 방법
US9534058B2 (en) 2012-02-08 2017-01-03 Abbvie Stemcentrx Llc Anti-CD324 monoclonal antibodies and uses thereof
WO2013123084A1 (en) * 2012-02-13 2013-08-22 Minerva Biotechnologies Corporation Method for detecting circulating fetal cells
US9752181B2 (en) 2013-01-26 2017-09-05 Denovo Sciences, Inc. System and method for capturing and analyzing cells
WO2014120265A1 (en) 2013-02-02 2014-08-07 Duke University Method of isolating circulating tumor cells
US9707562B2 (en) 2013-03-13 2017-07-18 Denovo Sciences, Inc. System for capturing and analyzing cells
EP3608022A1 (de) 2013-03-15 2020-02-12 The Trustees of Princeton University Verfahren und vorrichtungen für reinigung mit hohem durchsatz
US11493428B2 (en) 2013-03-15 2022-11-08 Gpb Scientific, Inc. On-chip microfluidic processing of particles
US20150064153A1 (en) 2013-03-15 2015-03-05 The Trustees Of Princeton University High efficiency microfluidic purification of stem cells to improve transplants
US12590955B2 (en) 2013-03-15 2026-03-31 Zeon Corporation Methods and systems for processing particles
US9856535B2 (en) 2013-05-31 2018-01-02 Denovo Sciences, Inc. System for isolating cells
US10391490B2 (en) 2013-05-31 2019-08-27 Celsee Diagnostics, Inc. System and method for isolating and analyzing cells
TW201623605A (zh) 2014-04-01 2016-07-01 中央研究院 用於癌症診斷及預後之方法及系統
US20160130553A1 (en) 2014-05-15 2016-05-12 Kellbenx Incorporated PREPARATION OF FETAL NUCLEATED RED BLOOD CELLS (NRBCs) FOR DIAGNOSTIC TESTING
US10112198B2 (en) 2014-08-26 2018-10-30 Academia Sinica Collector architecture layout design
US12202890B1 (en) 2014-11-07 2025-01-21 Kellbenx Incorporated Antibodies for detection and enrichment of fetal cells and their use
US10976232B2 (en) 2015-08-24 2021-04-13 Gpb Scientific, Inc. Methods and devices for multi-step cell purification and concentration
US10107726B2 (en) 2016-03-16 2018-10-23 Cellmax, Ltd. Collection of suspended cells using a transferable membrane
US10391492B2 (en) 2017-08-29 2019-08-27 Celsee Diagnostics, Inc. System and method for isolating and analyzing cells
US10633693B1 (en) 2019-04-16 2020-04-28 Celsee Diagnostics, Inc. System and method for leakage control in a particle capture system
AU2020267743B2 (en) 2019-05-07 2023-04-06 Bio-Rad Laboratories, Inc. System and method for automated single cell processing
US11273439B2 (en) 2019-05-07 2022-03-15 Bio-Rad Laboratories, Inc. System and method for target material retrieval from microwells
WO2020251802A1 (en) 2019-06-14 2020-12-17 Bio-Rad Laboratories, Inc. System and method for automated single cell processing and analyses
CN118369438A (zh) 2021-12-10 2024-07-19 伯乐实验室有限公司 用形态可调节功能化颗粒进行样品处理的组合物、方法和系统

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US5744327A (en) * 1990-02-20 1998-04-28 Board Of Regents, The University Of Texas System Methods for producing insulin in response to non-glucose secretagogues
US5753631A (en) * 1990-06-15 1998-05-19 Cytel Corporation Intercellular adhesion mediators
US6984522B2 (en) * 2000-08-03 2006-01-10 Regents Of The University Of Michigan Isolation and use of solid tumor stem cells
CA2466896A1 (en) 2001-09-06 2003-03-20 Adnagen Ag Method and diagnosis kit for selecting and or qualitative and/or quantitative detection of cells
WO2003092679A1 (en) * 2002-04-30 2003-11-13 Array Biopharma, Inc. Preparation of phosphatase inhibitors
US20060141512A1 (en) * 2004-12-03 2006-06-29 Sinha Sudhir K Novel method for separation of human sperm from biological samples for application in human identification
US20070220621A1 (en) * 2005-10-31 2007-09-20 Clarke Michael F Genetic characterization and prognostic significance of cancer stem cells in cancer
US20080064098A1 (en) * 2006-06-05 2008-03-13 Cryo-Cell International, Inc. Procurement, isolation and cryopreservation of maternal placental cells
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Also Published As

Publication number Publication date
ES2374478T3 (es) 2012-02-17
US9488652B2 (en) 2016-11-08
ATE533049T1 (de) 2011-11-15
EP2201361A1 (de) 2010-06-30
EP2037266A1 (de) 2009-03-18
US20100285581A1 (en) 2010-11-11
WO2009036968A1 (en) 2009-03-26
US8557528B2 (en) 2013-10-15
EP2198287A1 (de) 2010-06-23
US8557577B2 (en) 2013-10-15
US20140045208A1 (en) 2014-02-13
US20140087391A1 (en) 2014-03-27
EP2198287B1 (de) 2011-11-09
WO2009036967A1 (en) 2009-03-26
EP2037265A1 (de) 2009-03-18
ES2366269T3 (es) 2011-10-18
EP2201361B1 (de) 2011-05-11
US20110236904A1 (en) 2011-09-29

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