ATE509636T1 - Kombination aus einem cholinesterase-hemmer und einer verbindung mit 5-ht6-rezeptor-affinität - Google Patents

Kombination aus einem cholinesterase-hemmer und einer verbindung mit 5-ht6-rezeptor-affinität

Info

Publication number: ATE509636T1
Authority: AT; Austria
Prior art keywords: compound; combination; cholinesterase inhibitor; receptor affinity; active substance
Prior art date: 2006-06-23

Application number

AT07765553T

Other languages

English (en)

Inventor

Xavier Codony-Soler

Helmut Heinrich Buschmann

Original Assignee

Esteve Labor Dr

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2006-06-23

Filing date

2007-06-22

Publication date

2011-06-15

2007-06-22 Application filed by Esteve Labor Dr filed Critical Esteve Labor Dr

2011-06-15 Application granted granted Critical

2011-06-15 Publication of ATE509636T1 publication Critical patent/ATE509636T1/de

Links

108091005435 5-HT6 receptors Proteins 0.000 title abstract 2
229940122041 Cholinesterase inhibitor Drugs 0.000 title abstract 2
239000000544 cholinesterase inhibitor Substances 0.000 title abstract 2
150000001875 compounds Chemical class 0.000 title abstract 2
239000013543 active substance Substances 0.000 abstract 3
239000003814 drug Substances 0.000 abstract 2
238000004519 manufacturing process Methods 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A—HUMAN NECESSITIES
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Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Cardiology (AREA)
Diabetes (AREA)
Heart & Thoracic Surgery (AREA)
Pain & Pain Management (AREA)
Epidemiology (AREA)
Obesity (AREA)
Hematology (AREA)
Reproductive Health (AREA)
Endocrinology (AREA)
Immunology (AREA)
Psychiatry (AREA)
Rheumatology (AREA)
Gynecology & Obstetrics (AREA)
Physical Education & Sports Medicine (AREA)
Hospice & Palliative Care (AREA)
Psychology (AREA)
Vascular Medicine (AREA)
Pulmonology (AREA)
Urology & Nephrology (AREA)
Orthopedic Medicine & Surgery (AREA)
Child & Adolescent Psychology (AREA)
Gastroenterology & Hepatology (AREA)

AT07765553T 2006-06-23 2007-06-22 Kombination aus einem cholinesterase-hemmer und einer verbindung mit 5-ht6-rezeptor-affinität ATE509636T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP06384012		2006-06-23
PCT/EP2007/056234 WO2007147883A1 (en)	2006-06-23	2007-06-22	Combination of a cholinesterase inhibitor and a compound with 5-ht6 receptor affinity

Publications (1)

Publication Number	Publication Date
ATE509636T1 true ATE509636T1 (de)	2011-06-15

Family

ID=37302308

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT07765553T ATE509636T1 (de)	2006-06-23	2007-06-22	Kombination aus einem cholinesterase-hemmer und einer verbindung mit 5-ht6-rezeptor-affinität

Country Status (10)

Country	Link
US (1)	US20100120747A1 (de)
EP (1)	EP2040755B1 (de)
JP (1)	JP2009541423A (de)
CN (1)	CN101500611A (de)
AT (1)	ATE509636T1 (de)
CA (1)	CA2658959A1 (de)
ES (1)	ES2366958T3 (de)
MX (1)	MX2008015996A (de)
PT (1)	PT2040755E (de)
WO (1)	WO2007147883A1 (de)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2008087123A2 (en) *	2007-01-16	2008-07-24	Solvay Pharmaceuticals B.V.	Use of 5-ht6 antagonists to prevent relapse into addiction
EP1953153A1 (de) *	2007-01-31	2008-08-06	Laboratorios del Dr. Esteve S.A.	Heterocyclyl-substituierte Sulfonamide für die Behandlung von Wahrnehmungsstörungen bzw. Ernährungserkrankungen
WO2009022346A2 (en) *	2007-08-14	2009-02-19	Yissum Research Development Company Of The Hebrew University Of Jerusalem	Phenyl carbamates for treating gastrointestinal inflammation
EP2508177A1 (de) *	2007-12-12	2012-10-10	Glaxo Group Limited	Kombinationen mit 3-phenylsulfonyl-8-piperazinyl-1yl-chinolin
RU2384581C2 (ru) *	2008-05-07	2010-03-20	Андрей Александрович Иващенко	ЗАМЕЩЕННЫЕ 2-АМИНО-3-СУЛЬФОНИЛ-ТЕТРАГИДРО-ПИРАЗОЛО[1,5-a]ПИРИДО-ПИРИМИДИНЫ - АНТАГОНИСТЫ СЕРОТОНИНОВЫХ 5-HT6 РЕЦЕПТОРОВ, СПОСОБЫ ИХ ПОЛУЧЕНИЯ И ПРИМЕНЕНИЯ
RU2391343C1 (ru) *	2008-09-24	2010-06-10	Андрей Александрович Иващенко	ТЕТРАГИДРО-ПИРАЗОЛО[1,5-a]ПИРИДО-ПИРИМИДИНЫ - АНТАГОНИСТЫ СЕРОТОНИНОВЫХ 5-HT6 РЕЦЕПТОРОВ, СПОСОБЫ ИХ ПОЛУЧЕНИЯ И ПРИМЕНЕНИЯ
US9126946B2 (en)	2008-10-28	2015-09-08	Arena Pharmaceuticals, Inc.	Processes useful for the preparation of 1-[3-(4-bromo-2-methyl-2H-pyrazol-3-yl)-4-methoxy-phenyl]-3-(2,4-difluoro-phenyl)urea and crystalline forms related thereto
WO2011082400A2 (en) *	2010-01-04	2011-07-07	President And Fellows Of Harvard College	Modulators of immunoinhibitory receptor pd-1, and methods of use thereof
CN101953829A (zh) *	2010-08-03	2011-01-26	中国人民解放军第二军医大学	欧芹素乙在制备抗肿瘤药物中的应用
WO2013055386A2 (en)	2011-10-03	2013-04-18	The University Of Utah Research Foundation	Application of 5-ht6 receptor antagonists for the alleviation of cognitive deficits of down syndrome
US9084800B2 (en) *	2011-11-07	2015-07-21	Natreon, Inc.	Indolealkylamino-withasteroid conjugates and method of use
EP2647377A1 (de)	2012-04-06	2013-10-09	Sanofi	Verwendung eines H3-Rezeptorantagonisten zur Behandlung von Morbus Alzheimer
JO3459B1 (ar)	2012-09-09	2020-07-05	H Lundbeck As	تركيبات صيدلانية لعلاج مرض الزهايمر
CN105764510A (zh) *	2013-09-09	2016-07-13	赛诺菲	H3受体拮抗剂与胆碱酶抑制剂组合用于阿尔茨海默氏病治疗中的用途
PT3074033T (pt) *	2013-11-26	2019-02-08	Childrens Medical Ct Corp	Compostos para o tratamento de obesidade e métodos de utilização dos mesmos
CN103948036B (zh) *	2014-05-13	2015-11-25	陈金杰	一种抗神经衰弱的保健品及其应用
JP2018515607A (ja) *	2015-05-07	2018-06-14	アクソファントサイエンシーズゲーエムベーハーＡｘｏｖａｎｔＳｃｉｅｎｃｅｓＧｍｂｈ	神経変性疾患を処置する組成物および方法
CN104983715B (zh) *	2015-05-19	2017-11-17	北京联合大学	一种盐酸小檗碱微囊的制备方法
US10022355B2 (en)	2015-06-12	2018-07-17	Axovant Sciences Gmbh	Diaryl and arylheteroaryl urea derivatives as modulators of the 5-HT2A serotonin receptor useful for the prophylaxis and treatment of REM sleep behavior disorder
BR112018000728A2 (pt)	2015-07-15	2018-09-04	Axovant Sciences Gmbh	resumo método para a profilaxia e/ou tratamento de alucinações visuais em um sujeito com necessidade do mesmo
KR101781060B1 (ko)	2016-02-23	2017-09-25	주식회사 레스코퍼레이션	허혈성 뇌졸중의 치료 및 예방용 약학 조성물
US10383849B2 (en) *	2016-04-26	2019-08-20	H. Lundbeck A/S	Use of an acetylcholinesterase inhibitor and idalopirdine for reducing falls in Parkinson's disease patients
EA036347B1 (ru)	2016-05-18	2020-10-29	Сувен Лайф Сайенсиз Лимитед	Комбинация чистых антагонистов 5-ht6 рецепторов с ингибиторами ацетилхолинэстеразы
CN111727040A (zh) *	2018-02-19	2020-09-29	纳特雷恩公司	用于改善认知能力或认知功能的尿石素a和b的协同组合
MX2021003904A (es)	2018-10-05	2021-10-26	Annapurna Bio Inc	Compuestos y composiciones para el tratamiento de afecciones asociadas con la actividad del receptor apj.
CN109439705B (zh) *	2018-12-05	2021-10-01	广州中医药大学(广州中医药研究院)	一种柳珊瑚酸的微生物制备方法
PT4426434T (pt)	2021-11-02	2025-11-24	Flare Therapeutics Inc	Agonistas inversos de pparg e suas utilizações

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
PT1009387E (pt) *	1997-07-02	2006-08-31	Euro Celtique Sa	Formulacoes estabilizadas de libertacao controlada de tramadol
US6193993B1 (en) *	1998-03-03	2001-02-27	Eisai Co., Ltd.	Suppository containing an antidementia medicament
US7034029B2 (en) *	2000-11-02	2006-04-25	Wyeth	1-aryl- or 1-alkylsulfonyl-heterocyclylbenzazoles as 5-hydroxytryptamine-6 ligands
BR0211561A (pt) *	2001-08-03	2004-11-30	Upjohn Co	Compostos e composições de 5-arilsulfonil indóis tendo afinidade para receptor 5-ht6 e seus usos
US6906095B2 (en) *	2002-05-10	2005-06-14	Wyeth	Indolylalkylidenehydrazine-carboximidamide derivatives as 5-hydroxytryptamine-6 ligands
US6951881B2 (en) *	2002-05-10	2005-10-04	Wyeth	(1-substituted-indol-3-yl) alkylidenehydrazinecarboximidamide derivatives as 5-hydroxytryptamine-6 ligands
US6875771B2 (en) *	2002-07-26	2005-04-05	Bristol-Myers Squibb Company	Pyridopyrimidine derivatives as 5-HT6 antagonists
PL377770A1 (pl) *	2002-11-08	2006-02-20	F. Hoffmann-La Roche Ag	Podstawione benzoksazynony i ich zastosowanie
EP1592683A2 (de) *	2003-02-14	2005-11-09	Wyeth	Heterozyklyl-3-sulfonylindazole als 5-hydroxytryptamin-6-liganden
ES2228268B1 (es) *	2003-07-30	2006-07-01	Laboratorios Del Dr. Esteve, S.A.	Combinacion de sustancias activas conteniendo al menos un compuesto con afinidad por el receptor del neuropeptido y (npy) y al menos un compuesto con afinidad por el receptor 5-ht6.
TW200524864A (en) *	2003-11-10	2005-08-01	Wyeth Corp	Sulfonyltetrahydro-3H-benzo(E)indole-8-amine compounds as 5-hydroxytryptamine-6 ligands
EP1632491A1 (de) *	2004-08-30	2006-03-08	Laboratorios Del Dr. Esteve, S.A.	Substituierte indol-verbindungen und deren verwendung als modulatoren des 5-ht6 rezeptors
PE20071143A1 (es) *	2006-01-13	2008-01-20	Wyeth Corp	Composicion farmaceutica que comprende un inhibidor de acetilcolinesterasa y un antagonista 5-hidroxitriptamina-6

2007
- 2007-06-22 JP JP2009517134A patent/JP2009541423A/ja active Pending
- 2007-06-22 WO PCT/EP2007/056234 patent/WO2007147883A1/en not_active Ceased
- 2007-06-22 MX MX2008015996A patent/MX2008015996A/es active IP Right Grant
- 2007-06-22 AT AT07765553T patent/ATE509636T1/de active
- 2007-06-22 EP EP07765553A patent/EP2040755B1/de not_active Not-in-force
- 2007-06-22 PT PT07765553T patent/PT2040755E/pt unknown
- 2007-06-22 ES ES07765553T patent/ES2366958T3/es active Active
- 2007-06-22 US US12/305,516 patent/US20100120747A1/en not_active Abandoned
- 2007-06-22 CA CA002658959A patent/CA2658959A1/en not_active Abandoned
- 2007-06-22 CN CNA2007800251169A patent/CN101500611A/zh active Pending

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WO2007147883A1 (en)	2007-12-27
JP2009541423A (ja)	2009-11-26
HK1132175A1 (en)	2010-02-19
PT2040755E (pt)	2011-07-08
ES2366958T3 (es)	2011-10-27
EP2040755A1 (de)	2009-04-01
MX2008015996A (es)	2009-01-20
EP2040755B1 (de)	2011-05-18
CN101500611A (zh)	2009-08-05
CA2658959A1 (en)	2007-12-27
US20100120747A1 (en)	2010-05-13

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