CL2007001838A1 - Compuestos derivados de 4-oxoquinolina; composicion farmaceutica; y uso del compuesto para la produccion de un agente anti-vih. - Google Patents
Compuestos derivados de 4-oxoquinolina; composicion farmaceutica; y uso del compuesto para la produccion de un agente anti-vih.Info
- Publication number
- CL2007001838A1 CL2007001838A1 CL200701838A CL2007001838A CL2007001838A1 CL 2007001838 A1 CL2007001838 A1 CL 2007001838A1 CL 200701838 A CL200701838 A CL 200701838A CL 2007001838 A CL2007001838 A CL 2007001838A CL 2007001838 A1 CL2007001838 A1 CL 2007001838A1
- Authority
- CL
- Chile
- Prior art keywords
- oxoquinoline
- compound
- production
- pharmaceutical composition
- compounds derived
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title 2
- 239000002259 anti human immunodeficiency virus agent Substances 0.000 title 1
- 229940124411 anti-hiv antiviral agent Drugs 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- PMZDQRJGMBOQBF-UHFFFAOYSA-N quinolin-4-ol Chemical compound C1=CC=C2C(O)=CC=NC2=C1 PMZDQRJGMBOQBF-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
- C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing aromatic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Virology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Communicable Diseases (AREA)
- Molecular Biology (AREA)
- Tropical Medicine & Parasitology (AREA)
- AIDS & HIV (AREA)
- Oncology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Quinoline Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2006174331 | 2006-06-23 | ||
| JP2006220082 | 2006-08-11 | ||
| JP2006274143 | 2006-10-05 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CL2007001838A1 true CL2007001838A1 (es) | 2008-02-08 |
Family
ID=38833517
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CL200701838A CL2007001838A1 (es) | 2006-06-23 | 2007-06-22 | Compuestos derivados de 4-oxoquinolina; composicion farmaceutica; y uso del compuesto para la produccion de un agente anti-vih. |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US7872004B2 (es) |
| EP (2) | EP2033954A4 (es) |
| JP (1) | JP4038231B1 (es) |
| KR (1) | KR101053811B1 (es) |
| AR (1) | AR061583A1 (es) |
| AU (1) | AU2007262010B2 (es) |
| BR (1) | BRPI0713336A2 (es) |
| CA (1) | CA2653830C (es) |
| CL (1) | CL2007001838A1 (es) |
| CO (1) | CO6150181A2 (es) |
| IL (1) | IL195862A0 (es) |
| MX (1) | MX2009000159A (es) |
| MY (1) | MY144773A (es) |
| NO (1) | NO20090322L (es) |
| NZ (1) | NZ573709A (es) |
| PE (1) | PE20080211A1 (es) |
| SA (1) | SA07280343B1 (es) |
| TW (1) | TW200811153A (es) |
| WO (1) | WO2007148780A1 (es) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SK2662004A3 (sk) * | 2002-11-20 | 2005-06-02 | Japan Tobacco, Inc. | Zlúčenina s obsahom 4-oxochinolínu a jej použitie ako inhibítora integráz |
| WO2008033836A2 (en) * | 2006-09-12 | 2008-03-20 | Gilead Sciences, Inc. | Process and intermediates for preparing integrase inhibitors |
| AR068403A1 (es) * | 2007-09-11 | 2009-11-18 | Gilead Sciences Inc | Proceso e intermediarios para la preparacion de inhibidores de integrasa |
| ES2446720T3 (es) | 2009-10-13 | 2014-03-10 | Elanco Animal Health Ireland Limited | Inhibidores de la integrasa macrocíclica |
| WO2011121105A1 (en) | 2010-04-02 | 2011-10-06 | Tibotec Pharmaceuticals | Macrocyclic integrase inhibitors |
| ES3018133T3 (en) | 2011-11-30 | 2025-05-14 | Univ Emory | Jak inhibitors for use in the prevention or treatment of a viral disease caused by a coronaviridae |
| AU2013296289B2 (en) | 2012-08-03 | 2017-10-05 | Gilead Sciences, Inc. | Process and intermediates for preparing integrase inhibitors |
| MY201239A (en) | 2019-03-22 | 2024-02-13 | Gilead Sciences Inc | Bridged tricyclic carbamoylpyridone compounds and their pharmaceutical use |
| PE20221569A1 (es) | 2020-02-24 | 2022-10-06 | Gilead Sciences Inc | Compuestos tetraciclicos para el tratamiento de infecciones por vih |
| ES3064867T3 (en) | 2020-09-30 | 2026-04-29 | Gilead Sciences Inc | Bridged tricyclic carbamoylpyridone compounds for a use in the treatment of hiv |
| US11613546B2 (en) | 2021-01-19 | 2023-03-28 | Gilead Sciences, Inc. | Substituted pyridotriazine compounds and uses thereof |
| TW202446773A (zh) | 2022-04-06 | 2024-12-01 | 美商基利科學股份有限公司 | 橋聯三環胺甲醯基吡啶酮化合物及其用途 |
| CN115448866B (zh) * | 2022-10-13 | 2023-11-21 | 中北大学 | 一种1-甲基-2,3,4,5-四硝基吡咯的制备方法 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SK286420B6 (sk) | 1997-09-15 | 2008-09-05 | The Procter & Gamble Company | Zlúčenina so štruktúrou chinolónu, farmaceutický prostriedok s jej obsahom a jej použitie |
| WO2004004611A1 (en) | 2002-07-08 | 2004-01-15 | Coloplast A/S | Conduit device |
| SK2662004A3 (sk) | 2002-11-20 | 2005-06-02 | Japan Tobacco, Inc. | Zlúčenina s obsahom 4-oxochinolínu a jej použitie ako inhibítora integráz |
| EP1730135B1 (en) | 2004-03-10 | 2010-09-22 | The United States of America, represented by the Secretary, Department of Health and Human Services | Qiunolin-4-ones as inhibitors of retroviral integrase for the treatment of hiv, aids and aids related complex (arc) |
| US7531554B2 (en) | 2004-05-20 | 2009-05-12 | Japan Tobacco Inc. | 4-oxoquinoline compound and use thereof as HIV integrase inhibitor |
| WO2006033422A1 (ja) | 2004-09-21 | 2006-03-30 | Japan Tobacco Inc. | キノリジノン化合物、およびそのｈｉｖインテグラーゼ阻害剤としての利用 |
| US7745459B2 (en) | 2004-09-21 | 2010-06-29 | Japan Tobacco Inc. | Quinolizinone compound and use thereof as HIV integrase inhibitor |
| JP2006174331A (ja) | 2004-12-20 | 2006-06-29 | Fuji Xerox Co Ltd | 画像圧縮装置、画像圧縮方法及びそのプログラム |
| JP2006220082A (ja) | 2005-02-10 | 2006-08-24 | Denso Corp | 燃料噴射装置 |
| JP4572720B2 (ja) | 2005-03-30 | 2010-11-04 | Ｄｉｃ株式会社 | 水分散型アクリル系樹脂の製造方法、並びにそれにより製造される水分散型アクリル粘着剤組成物及び粘着シート |
| DE102006005861A1 (de) | 2006-02-09 | 2007-08-23 | Aicuris Gmbh & Co. Kg | Substituierte Chinolone III |
-
2007
- 2007-06-21 TW TW096122234A patent/TW200811153A/zh unknown
- 2007-06-22 AR ARP070102755A patent/AR061583A1/es not_active Application Discontinuation
- 2007-06-22 EP EP07845259A patent/EP2033954A4/en not_active Withdrawn
- 2007-06-22 EP EP11168760A patent/EP2368880A1/en not_active Withdrawn
- 2007-06-22 AU AU2007262010A patent/AU2007262010B2/en not_active Ceased
- 2007-06-22 US US11/767,021 patent/US7872004B2/en not_active Expired - Fee Related
- 2007-06-22 WO PCT/JP2007/062579 patent/WO2007148780A1/ja not_active Ceased
- 2007-06-22 NZ NZ573709A patent/NZ573709A/en not_active IP Right Cessation
- 2007-06-22 KR KR1020097001497A patent/KR101053811B1/ko not_active Expired - Fee Related
- 2007-06-22 MX MX2009000159A patent/MX2009000159A/es active IP Right Grant
- 2007-06-22 JP JP2007164676A patent/JP4038231B1/ja not_active Expired - Fee Related
- 2007-06-22 BR BRPI0713336-7A patent/BRPI0713336A2/pt not_active IP Right Cessation
- 2007-06-22 CL CL200701838A patent/CL2007001838A1/es unknown
- 2007-06-22 PE PE2007000805A patent/PE20080211A1/es not_active Application Discontinuation
- 2007-06-22 CA CA2653830A patent/CA2653830C/en not_active Expired - Fee Related
- 2007-06-23 SA SA7280343A patent/SA07280343B1/ar unknown
-
2008
- 2008-12-10 MY MYPI20085006A patent/MY144773A/en unknown
- 2008-12-11 IL IL195862A patent/IL195862A0/en unknown
-
2009
- 2009-01-16 CO CO09003378A patent/CO6150181A2/es unknown
- 2009-01-21 NO NO20090322A patent/NO20090322L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| MY144773A (en) | 2011-10-31 |
| BRPI0713336A2 (pt) | 2012-11-06 |
| TW200811153A (en) | 2008-03-01 |
| JP2008110960A (ja) | 2008-05-15 |
| CA2653830C (en) | 2011-11-22 |
| KR101053811B1 (ko) | 2011-08-03 |
| IL195862A0 (en) | 2009-09-01 |
| NO20090322L (no) | 2009-03-20 |
| JP4038231B1 (ja) | 2008-01-23 |
| EP2033954A1 (en) | 2009-03-11 |
| PE20080211A1 (es) | 2008-04-23 |
| AU2007262010A1 (en) | 2007-12-27 |
| EP2368880A1 (en) | 2011-09-28 |
| AR061583A1 (es) | 2008-09-03 |
| CO6150181A2 (es) | 2010-04-20 |
| CA2653830A1 (en) | 2007-12-27 |
| SA07280343B1 (ar) | 2011-01-15 |
| NZ573709A (en) | 2011-04-29 |
| KR20090023731A (ko) | 2009-03-05 |
| MX2009000159A (es) | 2009-01-23 |
| AU2007262010B2 (en) | 2011-05-12 |
| WO2007148780A1 (ja) | 2007-12-27 |
| EP2033954A4 (en) | 2009-08-12 |
| US20080207618A1 (en) | 2008-08-28 |
| US7872004B2 (en) | 2011-01-18 |
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