ATE509649T1 - Vorrichtung zur blutbehandlung mit selektiver entfernung gelöster substanzen - Google Patents

Vorrichtung zur blutbehandlung mit selektiver entfernung gelöster substanzen

Info

Publication number
ATE509649T1
ATE509649T1 AT04720673T AT04720673T ATE509649T1 AT E509649 T1 ATE509649 T1 AT E509649T1 AT 04720673 T AT04720673 T AT 04720673T AT 04720673 T AT04720673 T AT 04720673T AT E509649 T1 ATE509649 T1 AT E509649T1
Authority
AT
Austria
Prior art keywords
blood treatment
selective removal
dissolved substances
inlet
outlet
Prior art date
Application number
AT04720673T
Other languages
English (en)
Inventor
Jacques Chevallet
Guy Mercier
Hiram Rada
Mehran Monchi
Original Assignee
Gambro Lundia Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gambro Lundia Ab filed Critical Gambro Lundia Ab
Application granted granted Critical
Publication of ATE509649T1 publication Critical patent/ATE509649T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Disinfection or sterilisation of materials or objects, in general; Accessories therefor
    • A61L2/02—Disinfection or sterilisation of materials or objects, in general; Accessories therefor using physical processes
    • A61L2/022—Filtration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
    • A61M1/342—Adding solutions to the blood, e.g. substitution solutions
    • A61M1/3424—Substitution fluid path
    • A61M1/3431—Substitution fluid path upstream of the filter
    • A61M1/3434—Substitution fluid path upstream of the filter with pre-dilution and post-dilution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Disinfection or sterilisation of materials or objects, in general; Accessories therefor
    • A61L2/02—Disinfection or sterilisation of materials or objects, in general; Accessories therefor using physical processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A61M1/1694—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes with recirculating dialysing liquid
    • A61M1/1696—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes with recirculating dialysing liquid with dialysate regeneration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
    • A61M1/342—Adding solutions to the blood, e.g. substitution solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
    • A61M1/342—Adding solutions to the blood, e.g. substitution solutions
    • A61M1/3424—Substitution fluid path
    • A61M1/3437—Substitution fluid path downstream of the filter, e.g. post-dilution with filtrate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
    • A61M1/342—Adding solutions to the blood, e.g. substitution solutions
    • A61M1/3441—Substitution rate control as a function of the ultrafiltration rate
    • A61M1/3451—Substitution rate control as a function of the ultrafiltration rate the difference in weight between both ultra-filtrate and substitution reservoir being used as control signal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
    • A61M1/342—Adding solutions to the blood, e.g. substitution solutions
    • A61M1/3455—Substitution fluids
    • A61M1/3468—Substitution fluids using treated filtrate as substitution fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
    • A61M1/3472—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration with treatment of the filtrate
    • A61M1/3479—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration with treatment of the filtrate by dialysing the filtrate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
    • A61M1/3472—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration with treatment of the filtrate
    • A61M1/3482—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration with treatment of the filtrate by filtrating the filtrate using another cross-flow filter, e.g. a membrane filter
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
    • A61M1/3472—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration with treatment of the filtrate
    • A61M1/3486—Biological, chemical treatment, e.g. chemical precipitation; treatment by absorbents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
    • A61M1/3496—Plasmapheresis; Leucopheresis; Lymphopheresis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2103/00—Materials or objects being the target of disinfection or sterilisation
    • A61L2103/05—Living organisms or biological materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3681—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by irradiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/75—General characteristics of the apparatus with filters

Landscapes

  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Vascular Medicine (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Urology & Nephrology (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Cell Biology (AREA)
  • Molecular Biology (AREA)
  • Emergency Medicine (AREA)
  • Cardiology (AREA)
  • External Artificial Organs (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
AT04720673T 2003-03-17 2004-03-15 Vorrichtung zur blutbehandlung mit selektiver entfernung gelöster substanzen ATE509649T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0303257A FR2852515B1 (fr) 2003-03-17 2003-03-17 Dispositif et procede de traitement de sang avec extraction selective de solutes
PCT/IB2004/000896 WO2004082733A2 (fr) 2003-03-17 2004-03-15 Dispositif et procede de traitement de sang avec extraction selective de solutes

Publications (1)

Publication Number Publication Date
ATE509649T1 true ATE509649T1 (de) 2011-06-15

Family

ID=32922232

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04720673T ATE509649T1 (de) 2003-03-17 2004-03-15 Vorrichtung zur blutbehandlung mit selektiver entfernung gelöster substanzen

Country Status (10)

Country Link
EP (2) EP1603609B1 (de)
JP (1) JP4571621B2 (de)
KR (1) KR101047970B1 (de)
CN (1) CN1761494B (de)
AT (1) ATE509649T1 (de)
CA (1) CA2518969C (de)
ES (1) ES2365136T3 (de)
FR (1) FR2852515B1 (de)
PL (1) PL1603609T3 (de)
WO (1) WO2004082733A2 (de)

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DE102004054747A1 (de) * 2004-11-12 2006-05-24 Fresenius Medical Care Deutschland Gmbh Verfahren und Vorrichtung zur Abreicherung wenigstens einer Komponente eines fluiden Mediums
SE532147C2 (sv) 2005-02-16 2009-11-03 Triomed Ab Bärbart dialyssystem
EP2002855B1 (de) * 2007-06-14 2012-07-11 RenApta B.V. Künstliche Niere
US8298167B2 (en) * 2008-11-03 2012-10-30 B. Braun Avitum Ag Modular hemofiltration apparatus with interactive operator instructions and control system
JP5711214B2 (ja) * 2009-04-23 2015-04-30 フレゼニウス メディカル ケア ドイッチェランド ゲゼルシャフト ミット ベシュレンクテル ハフツング 外部機能手段、本発明に係る外部機能手段を受けるための血液処理機器、および、方法
DE102009026901A1 (de) 2009-06-10 2010-12-16 Fresenius Medical Care Deutschland Gmbh Dialysevorrichtung
JP5566461B2 (ja) * 2009-09-08 2014-08-06 フレゼニウス メディカル ケア ホールディングス インコーポレイテッド 腹膜透析システム
CN102107032B (zh) * 2009-12-29 2014-08-27 重庆医科大学 作用于血液中低分子物质的大分子药物的体外给药装置及其应用
KR101227453B1 (ko) * 2010-07-29 2013-01-29 서강대학교산학협력단 인공 신단위 장치
US9475709B2 (en) 2010-08-25 2016-10-25 Lockheed Martin Corporation Perforated graphene deionization or desalination
ES2561461T3 (es) * 2010-09-30 2016-02-26 Gambro Lundia Ab Aparato para el tratamiento extracorpóreo de la sangre
DE102011018601B4 (de) 2011-04-21 2017-04-06 Fresenius Medical Care Deutschland Gmbh Vorrichtung zur extrakorporalen Blutbehandlung und Verfahren zur Überwachung der Flüssigkeitsströmung einer extrakorporalen Blutbehandlungsvorrichtung
DE102011108784A1 (de) * 2011-07-29 2013-01-31 Fresenius Medical Care Deutschland Gmbh Verfahren sowie Vorrichtungen zum Überprüfen wenigstens einer Funktion einer medizinischen Funktionseinrichtung
ES2500966T3 (es) * 2011-08-30 2014-10-01 Gambro Lundia Ab Aparato para el tratamiento extracorpóreo de sangre, y proceso de cálculo de caudales fijados en un aparato médico para la entrega o recogida de fluidos
ES2532081T3 (es) * 2012-03-28 2015-03-24 Gambro Lundia Ab Aparato para tratamiento extracorpóreo de sangre
US9744617B2 (en) 2014-01-31 2017-08-29 Lockheed Martin Corporation Methods for perforating multi-layer graphene through ion bombardment
US9834809B2 (en) 2014-02-28 2017-12-05 Lockheed Martin Corporation Syringe for obtaining nano-sized materials for selective assays and related methods of use
US10017852B2 (en) 2016-04-14 2018-07-10 Lockheed Martin Corporation Method for treating graphene sheets for large-scale transfer using free-float method
US10376845B2 (en) 2016-04-14 2019-08-13 Lockheed Martin Corporation Membranes with tunable selectivity
US10653824B2 (en) 2012-05-25 2020-05-19 Lockheed Martin Corporation Two-dimensional materials and uses thereof
TW201504140A (zh) 2013-03-12 2015-02-01 Lockheed Corp 形成具有均勻孔尺寸之多孔石墨烯之方法
US9572918B2 (en) 2013-06-21 2017-02-21 Lockheed Martin Corporation Graphene-based filter for isolating a substance from blood
CA2938305A1 (en) 2014-01-31 2015-08-06 Lockheed Martin Corporation Processes for forming composite structures with a two-dimensional material using a porous, non-sacrificial supporting layer
KR20160142820A (ko) 2014-01-31 2016-12-13 록히드 마틴 코포레이션 브로드 이온 필드를 사용한 2차원 물질 천공
AU2015229331A1 (en) 2014-03-12 2016-10-27 Lockheed Martin Corporation Separation membranes formed from perforated graphene
SG11201701654UA (en) 2014-09-02 2017-04-27 Lockheed Corp Hemodialysis and hemofiltration membranes based upon a two-dimensional membrane material and methods employing same
AU2016303048A1 (en) 2015-08-05 2018-03-01 Lockheed Martin Corporation Perforatable sheets of graphene-based material
WO2017023377A1 (en) 2015-08-06 2017-02-09 Lockheed Martin Corporation Nanoparticle modification and perforation of graphene
SG11201809016QA (en) 2016-04-14 2018-11-29 Lockheed Corp Selective interfacial mitigation of graphene defects
WO2017180134A1 (en) 2016-04-14 2017-10-19 Lockheed Martin Corporation Methods for in vivo and in vitro use of graphene and other two-dimensional materials
KR20180133430A (ko) 2016-04-14 2018-12-14 록히드 마틴 코포레이션 결함 형성 또는 힐링의 인 시츄 모니터링 및 제어를 위한 방법
WO2017180139A1 (en) 2016-04-14 2017-10-19 Lockheed Martin Corporation Two-dimensional membrane structures having flow passages
TWI765069B (zh) 2017-07-18 2022-05-21 德商費森尤斯醫療護理德國有限責任公司 廢液袋、廢液袋之排液方法、排放軟管系統及血液處理設備
JP7305758B2 (ja) 2018-09-29 2023-07-10 フレセニウス・メディカル・ケア・ドイチュラント・ゲーエムベーハー 界面媒体と共に使用するための透析デバイス、透析システム、透析デバイスの使用、透析システムを確立するための方法、透析システムを充填および／またはプライミングするための方法、ならびに透析システムから空気を除去するための方法
WO2021203144A1 (en) * 2020-04-02 2021-10-07 Nuwellis, Inc. Multi-stage blood filtration
KR102718437B1 (ko) * 2020-07-20 2024-10-16 울산과학기술원 유체 장치를 이용하여 혈액 내 감염성 물질 또는 혈전을 제거하는 혈액 투석 장치 및 혈액 투석 방법
US11364330B2 (en) 2020-11-10 2022-06-21 Alfredo R. Zarate System and method for facilitating extracorporeal inactivation of pathogens of blood products
US11904078B2 (en) 2021-05-28 2024-02-20 Diality Inc. Hemodialysis system with variable dialysate flow rate
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WO2025029952A1 (en) * 2023-07-31 2025-02-06 Diality Inc. Hemodialysis system with variable dialysate flow rate

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Also Published As

Publication number Publication date
WO2004082733A8 (fr) 2005-04-07
FR2852515B1 (fr) 2005-11-18
JP2006520635A (ja) 2006-09-14
KR101047970B1 (ko) 2011-07-13
JP4571621B2 (ja) 2010-10-27
CN1761494A (zh) 2006-04-19
ES2365136T3 (es) 2011-09-23
AU2004222460A1 (en) 2004-09-30
EP1603609B1 (de) 2011-05-18
EP1603609A2 (de) 2005-12-14
EP2324870A1 (de) 2011-05-25
CN1761494B (zh) 2010-04-07
WO2004082733A9 (fr) 2005-02-17
PL1603609T3 (pl) 2011-12-30
KR20050113232A (ko) 2005-12-01
FR2852515A1 (fr) 2004-09-24
CA2518969A1 (en) 2004-09-30
EP2324870B1 (de) 2016-06-01
WO2004082733A3 (fr) 2004-11-04
CA2518969C (en) 2011-05-24
WO2004082733A2 (fr) 2004-09-30

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