ATE509681T1 - Kationenaustausch- verdrängungschromatographieverfahren und kationische organische verbindungen zur verwendung als verdrängerverbindungen bei einem kationenaustausch- verdrängungschromatographieverfahren - Google Patents

Kationenaustausch- verdrängungschromatographieverfahren und kationische organische verbindungen zur verwendung als verdrängerverbindungen bei einem kationenaustausch- verdrängungschromatographieverfahren

Info

Publication number
ATE509681T1
ATE509681T1 AT06826489T AT06826489T ATE509681T1 AT E509681 T1 ATE509681 T1 AT E509681T1 AT 06826489 T AT06826489 T AT 06826489T AT 06826489 T AT06826489 T AT 06826489T AT E509681 T1 ATE509681 T1 AT E509681T1
Authority
AT
Austria
Prior art keywords
cation exchange
chromatography process
displacement
compounds
displacement chromatography
Prior art date
Application number
AT06826489T
Other languages
English (en)
Inventor
Charles Little
De Pas Victor Van
Barry Haymore
Original Assignee
Sachem Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sachem Inc filed Critical Sachem Inc
Application granted granted Critical
Publication of ATE509681T1 publication Critical patent/ATE509681T1/de

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D15/00Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08Selective adsorption, e.g. chromatography
    • B01D15/42Selective adsorption, e.g. chromatography characterised by the development mode, e.g. by displacement or by elution
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D15/00Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08Selective adsorption, e.g. chromatography
    • B01D15/42Selective adsorption, e.g. chromatography characterised by the development mode, e.g. by displacement or by elution
    • B01D15/422Displacement mode
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D15/00Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08Selective adsorption, e.g. chromatography
    • B01D15/26Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/36Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction, e.g. ion-exchange, ion-pair, ion-suppression or ion-exclusion
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G73/00Macromolecular compounds obtained by reactions forming a linkage containing nitrogen with or without oxygen or carbon in the main chain of the macromolecule, not provided for in groups C08G12/00 - C08G71/00
    • C08G73/02Polyamines
    • C08G73/0206Polyalkylene(poly)amines
    • C08G73/0213Preparatory process
    • C08G73/0226Quaternisation of polyalkylene(poly)amines
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/96Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation using ion-exchange

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biomedical Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Organic Chemistry (AREA)
  • Hematology (AREA)
  • Polymers & Plastics (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
AT06826489T 2005-11-04 2006-10-23 Kationenaustausch- verdrängungschromatographieverfahren und kationische organische verbindungen zur verwendung als verdrängerverbindungen bei einem kationenaustausch- verdrängungschromatographieverfahren ATE509681T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US26782305A 2005-11-04 2005-11-04
PCT/US2006/041328 WO2007055896A1 (en) 2005-11-04 2006-10-23 Cation-exchange displacement chromatography process and cationic organic compounds for use as displacer compounds in cation-exchange displacement chromatography process

Publications (1)

Publication Number Publication Date
ATE509681T1 true ATE509681T1 (de) 2011-06-15

Family

ID=37459509

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06826489T ATE509681T1 (de) 2005-11-04 2006-10-23 Kationenaustausch- verdrängungschromatographieverfahren und kationische organische verbindungen zur verwendung als verdrängerverbindungen bei einem kationenaustausch- verdrängungschromatographieverfahren

Country Status (12)

Country Link
US (2) US7632409B2 (de)
EP (1) EP1960077B1 (de)
JP (1) JP4917611B2 (de)
KR (1) KR101299158B1 (de)
CN (1) CN101346166B (de)
AT (1) ATE509681T1 (de)
CA (1) CA2628086C (de)
DK (1) DK1960077T3 (de)
ES (1) ES2362234T3 (de)
IL (1) IL191200A (de)
TW (1) TWI418406B (de)
WO (2) WO2007053235A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009135656A1 (en) * 2008-05-06 2009-11-12 Lonza Biologics Plc. A method for the purification of antibodies using displacement chromatography
US8277649B2 (en) * 2009-12-14 2012-10-02 General Electric Company Membranes and associated methods for purification of antibodies
KR101619865B1 (ko) 2010-07-30 2016-05-11 이엠디 밀리포어 코포레이션 크로마토그래피 매질
US8293115B2 (en) * 2011-01-20 2012-10-23 Gordon Rossiter Ionic impurities rejection and chromatographic purification using ion exchange
WO2013052539A2 (en) * 2011-10-03 2013-04-11 Sachem, Inc. Cationic displacer molecules for hydrophobic displacement chromatography
BR112014022827B1 (pt) * 2012-03-30 2019-10-15 Dow Global Technologies Llc Composto, e, método para fornecer umectância em uma composição de cuidados pessoais
WO2014142882A1 (en) 2013-03-14 2014-09-18 Abbvie Inc. Protein purification using displacement chromatography
CA2899449A1 (en) 2013-03-14 2014-10-02 Abbvie Inc. Low acidic species compositions and methods for producing the same using displacement chromatography
EP3188816B1 (de) 2014-09-02 2021-06-09 EMD Millipore Corporation Chromatographie-medum, bestehend aus diskreten porösen bündeln von nanofibrillen
EP3230299A1 (de) 2014-12-08 2017-10-18 EMD Millipore Corporation Mischbettionenaustauschadsorber
CN108144594A (zh) * 2016-12-05 2018-06-12 中国科学院大连化学物理研究所 两性离子聚合物固定相及其制备和应用

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2519441A (en) * 1949-06-29 1950-08-22 Rohm & Haas Tris-quaternary salts of 1, 3, 5-trisdimethylaminomethyl benzene and alkyl benzyl chlorides
US2807910A (en) * 1952-10-09 1957-10-01 Gen Mills Inc Soil conditioning with polyquaternary ammonium compounds
US3055939A (en) * 1957-06-03 1962-09-25 Irwin Neisler And Co Unsymmetric bis-ammonium salts
US3549370A (en) * 1966-11-23 1970-12-22 Hunt Chem Corp Philip A Quaternary ammonium bisulfites,sulfites or pyrosulfites as developer preservatives
US4166073A (en) * 1968-03-27 1979-08-28 Colgate Palmolive Company Unsymmetrical oligoquaternary ammonium compounds
US3493615A (en) * 1968-10-28 1970-02-03 Colgate Palmolive Co Surfactant anti-microbial compounds
US3719711A (en) * 1970-10-19 1973-03-06 Procter & Gamble Oligomeric quaternary ammonium antibacterial agents
CH575041B5 (de) * 1974-03-08 1976-04-30 Sandoz Ag
LU73795A1 (de) * 1975-11-13 1977-05-31 Oreal
ES479185A1 (es) * 1978-04-04 1980-08-16 Grain Processing Corp Un procedimiento para preparar pastas de almidon cationico.
CH635566A5 (de) * 1978-06-26 1983-04-15 Sandoz Ag Quaternierte polyamine und ihre herstellung.
IT1151548B (it) * 1982-04-29 1986-12-24 Aic Approvvigio Ind Chim Procedimento di tintura uniforme di fibre poliacrilonitriliche e fibre poliestere modificate anioniche e prodotti ritardanti e/o egualizzanti per esso
US5275744A (en) * 1991-09-30 1994-01-04 Chevron Research And Technology Company Derivatives of polyalkylenepolyamines as corrosion inhibitors
US6177577B1 (en) * 1991-11-15 2001-01-23 The Dow Chemical Company Dicationic and polycationic monoprimary alcohols and derivatives thereof
US5252216A (en) * 1992-03-24 1993-10-12 Smithkline Beecham Corporation Protein purification
GB9211760D0 (en) * 1992-06-03 1992-07-15 Gillette Co Correction fluids
US5545328A (en) * 1993-09-21 1996-08-13 Hemosol Inc. Purification of hemoglobin by displacement chromatography
US5478924A (en) * 1994-02-16 1995-12-26 Cramer; Steven M. Displacement chromatography of proteins using low molecular weight displacers
JPH07289238A (ja) * 1994-04-20 1995-11-07 Kurita Water Ind Ltd 核酸又はエンドトキシン除去材並びに除去方法
JP3828175B2 (ja) * 1995-01-06 2006-10-04 花王株式会社 多鎖型アミン誘導体及びその製造方法
US6239262B1 (en) * 1998-01-07 2001-05-29 Rensselaer Polytechnic Institute Low molecular weight displacers for protein purification in hydrophobic interaction and reversed phase chromatographic systems
EP0943632A1 (de) * 1998-03-18 1999-09-22 Ecole Polytechnique Federale De Lausanne Quaternäres Ammoniumpolymer, seine Herstellung, seine Verwendung in die Trennung von Biomolekülen
NZ512244A (en) * 1998-11-12 2003-12-19 Invitrogen Corp Polycationic transfection reagents for introducing anions into a cell
AU3236900A (en) * 1999-03-12 2000-10-04 Dow Chemical Company, The Process for preparing starch and epoxy-based thermoplastic polymer compositions
US6812198B2 (en) * 1999-11-09 2004-11-02 The Procter & Gamble Company Laundry detergent compositions comprising hydrophobically modified polyamines
AU2003213642A1 (en) * 2002-02-28 2003-09-16 Rensselaer Polytechnic Institute High-affinity, low-molecular-mass displacers for ion-exchange chromatography
US7214806B2 (en) * 2004-03-05 2007-05-08 Sachem, Inc. Synthetic multiple quaternary ammonium salts
KR101408026B1 (ko) * 2005-12-02 2014-06-20 사켐,인코포레이티드 음이온-교환 치환 크로마토그래피 공정 및 음이온-교환치환 크로마토그래피 공정에서 디스플레이서 화합물들로서사용하기 위한 음이온성 유기 화합물들

Also Published As

Publication number Publication date
IL191200A (en) 2013-10-31
US20100081844A1 (en) 2010-04-01
US20070102363A1 (en) 2007-05-10
WO2007055896A1 (en) 2007-05-18
US7632409B2 (en) 2009-12-15
CN101346166B (zh) 2012-01-18
CA2628086A1 (en) 2007-05-18
DK1960077T3 (da) 2011-08-29
EP1960077B1 (de) 2011-05-18
KR101299158B1 (ko) 2013-08-27
ES2362234T3 (es) 2011-06-30
TW200724235A (en) 2007-07-01
CN101346166A (zh) 2009-01-14
KR20080082613A (ko) 2008-09-11
WO2007053235A1 (en) 2007-05-10
JP4917611B2 (ja) 2012-04-18
HK1126713A1 (en) 2009-09-11
CA2628086C (en) 2011-04-05
JP2009515164A (ja) 2009-04-09
EP1960077A1 (de) 2008-08-27
TWI418406B (zh) 2013-12-11

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