ATE509681T1 - Kationenaustausch- verdrängungschromatographieverfahren und kationische organische verbindungen zur verwendung als verdrängerverbindungen bei einem kationenaustausch- verdrängungschromatographieverfahren - Google Patents

Kationenaustausch- verdrängungschromatographieverfahren und kationische organische verbindungen zur verwendung als verdrängerverbindungen bei einem kationenaustausch- verdrängungschromatographieverfahren

Info

Publication number
ATE509681T1
ATE509681T1 AT06826489T AT06826489T ATE509681T1 AT E509681 T1 ATE509681 T1 AT E509681T1 AT 06826489 T AT06826489 T AT 06826489T AT 06826489 T AT06826489 T AT 06826489T AT E509681 T1 ATE509681 T1 AT E509681T1
Authority
AT
Austria
Prior art keywords
cation exchange
chromatography process
displacement
compounds
displacement chromatography
Prior art date
Application number
AT06826489T
Other languages
English (en)
Inventor
Charles Little
De Pas Victor Van
Barry Haymore
Original Assignee
Sachem Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sachem Inc filed Critical Sachem Inc
Application granted granted Critical
Publication of ATE509681T1 publication Critical patent/ATE509681T1/de

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D15/00Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08Selective adsorption, e.g. chromatography
    • B01D15/42Selective adsorption, e.g. chromatography characterised by the development mode, e.g. by displacement or by elution
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D15/00Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08Selective adsorption, e.g. chromatography
    • B01D15/42Selective adsorption, e.g. chromatography characterised by the development mode, e.g. by displacement or by elution
    • B01D15/422Displacement mode
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D15/00Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08Selective adsorption, e.g. chromatography
    • B01D15/26Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/36Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction, e.g. ion-exchange, ion-pair, ion-suppression or ion-exclusion
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G73/00Macromolecular compounds obtained by reactions forming a linkage containing nitrogen with or without oxygen or carbon in the main chain of the macromolecule, not provided for in groups C08G12/00 - C08G71/00
    • C08G73/02Polyamines
    • C08G73/0206Polyalkylene(poly)amines
    • C08G73/0213Preparatory process
    • C08G73/0226Quaternisation of polyalkylene(poly)amines
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/96Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation using ion-exchange

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Polymers & Plastics (AREA)
  • Pathology (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Food Science & Technology (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
AT06826489T 2005-11-04 2006-10-23 Kationenaustausch- verdrängungschromatographieverfahren und kationische organische verbindungen zur verwendung als verdrängerverbindungen bei einem kationenaustausch- verdrängungschromatographieverfahren ATE509681T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US26782305A 2005-11-04 2005-11-04
PCT/US2006/041328 WO2007055896A1 (en) 2005-11-04 2006-10-23 Cation-exchange displacement chromatography process and cationic organic compounds for use as displacer compounds in cation-exchange displacement chromatography process

Publications (1)

Publication Number Publication Date
ATE509681T1 true ATE509681T1 (de) 2011-06-15

Family

ID=37459509

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06826489T ATE509681T1 (de) 2005-11-04 2006-10-23 Kationenaustausch- verdrängungschromatographieverfahren und kationische organische verbindungen zur verwendung als verdrängerverbindungen bei einem kationenaustausch- verdrängungschromatographieverfahren

Country Status (12)

Country Link
US (2) US7632409B2 (de)
EP (1) EP1960077B1 (de)
JP (1) JP4917611B2 (de)
KR (1) KR101299158B1 (de)
CN (1) CN101346166B (de)
AT (1) ATE509681T1 (de)
CA (1) CA2628086C (de)
DK (1) DK1960077T3 (de)
ES (1) ES2362234T3 (de)
IL (1) IL191200A (de)
TW (1) TWI418406B (de)
WO (2) WO2007053235A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009135656A1 (en) * 2008-05-06 2009-11-12 Lonza Biologics Plc. A method for the purification of antibodies using displacement chromatography
US8277649B2 (en) * 2009-12-14 2012-10-02 General Electric Company Membranes and associated methods for purification of antibodies
KR101627597B1 (ko) * 2010-07-30 2016-06-08 이엠디 밀리포어 코포레이션 부직포 층
US8293115B2 (en) * 2011-01-20 2012-10-23 Gordon Rossiter Ionic impurities rejection and chromatographic purification using ion exchange
EP2763773A2 (de) * 2011-10-03 2014-08-13 Sachem, Inc. Kationische verdrängermoleküle für hydrophobe verdrängungschromatographie
CN104159639A (zh) * 2012-03-30 2014-11-19 陶氏环球技术有限公司 聚阳离子多羟基化合物
HK1213919A1 (zh) 2013-03-14 2016-07-15 Abbvie Inc. 低酸性物質組合物和利用置換色譜技術製備該組合物的方法
WO2014142882A1 (en) 2013-03-14 2014-09-18 Abbvie Inc. Protein purification using displacement chromatography
CN106794389A (zh) 2014-09-02 2017-05-31 Emd密理博公司 具有纳米原纤化表面特征的高表面积纤维介质
CA2966515C (en) 2014-12-08 2021-04-27 Emd Millipore Corporation Mixed bed ion exchange adsorber
CN108144594A (zh) * 2016-12-05 2018-06-12 中国科学院大连化学物理研究所 两性离子聚合物固定相及其制备和应用

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2519441A (en) * 1949-06-29 1950-08-22 Rohm & Haas Tris-quaternary salts of 1, 3, 5-trisdimethylaminomethyl benzene and alkyl benzyl chlorides
US2807910A (en) * 1952-10-09 1957-10-01 Gen Mills Inc Soil conditioning with polyquaternary ammonium compounds
US3055939A (en) * 1957-06-03 1962-09-25 Irwin Neisler And Co Unsymmetric bis-ammonium salts
US3549370A (en) * 1966-11-23 1970-12-22 Hunt Chem Corp Philip A Quaternary ammonium bisulfites,sulfites or pyrosulfites as developer preservatives
US4166073A (en) * 1968-03-27 1979-08-28 Colgate Palmolive Company Unsymmetrical oligoquaternary ammonium compounds
US3493615A (en) * 1968-10-28 1970-02-03 Colgate Palmolive Co Surfactant anti-microbial compounds
US3719711A (en) * 1970-10-19 1973-03-06 Procter & Gamble Oligomeric quaternary ammonium antibacterial agents
CH575041B5 (de) * 1974-03-08 1976-04-30 Sandoz Ag
LU73795A1 (de) * 1975-11-13 1977-05-31 Oreal
ES479185A1 (es) 1978-04-04 1980-08-16 Grain Processing Corp Un procedimiento para preparar pastas de almidon cationico.
CH635566A5 (de) * 1978-06-26 1983-04-15 Sandoz Ag Quaternierte polyamine und ihre herstellung.
IT1151548B (it) * 1982-04-29 1986-12-24 Aic Approvvigio Ind Chim Procedimento di tintura uniforme di fibre poliacrilonitriliche e fibre poliestere modificate anioniche e prodotti ritardanti e/o egualizzanti per esso
US5275744A (en) * 1991-09-30 1994-01-04 Chevron Research And Technology Company Derivatives of polyalkylenepolyamines as corrosion inhibitors
US6177577B1 (en) 1991-11-15 2001-01-23 The Dow Chemical Company Dicationic and polycationic monoprimary alcohols and derivatives thereof
US5252216A (en) * 1992-03-24 1993-10-12 Smithkline Beecham Corporation Protein purification
GB9211760D0 (en) * 1992-06-03 1992-07-15 Gillette Co Correction fluids
US5545328A (en) * 1993-09-21 1996-08-13 Hemosol Inc. Purification of hemoglobin by displacement chromatography
US5478924A (en) * 1994-02-16 1995-12-26 Cramer; Steven M. Displacement chromatography of proteins using low molecular weight displacers
JPH07289238A (ja) * 1994-04-20 1995-11-07 Kurita Water Ind Ltd 核酸又はエンドトキシン除去材並びに除去方法
JP3828175B2 (ja) * 1995-01-06 2006-10-04 花王株式会社 多鎖型アミン誘導体及びその製造方法
US6239262B1 (en) * 1998-01-07 2001-05-29 Rensselaer Polytechnic Institute Low molecular weight displacers for protein purification in hydrophobic interaction and reversed phase chromatographic systems
EP0943632A1 (de) * 1998-03-18 1999-09-22 Ecole Polytechnique Federale De Lausanne Quaternäres Ammoniumpolymer, seine Herstellung, seine Verwendung in die Trennung von Biomolekülen
ES2296419T3 (es) * 1998-11-12 2008-04-16 Invitrogen Corporation Reactivos de transfeccion.
US6376583B1 (en) 1999-03-12 2002-04-23 The Dow Chemical Company Process for preparing starch and epoxy-based thermoplastic polymer compositions
US6812198B2 (en) * 1999-11-09 2004-11-02 The Procter & Gamble Company Laundry detergent compositions comprising hydrophobically modified polyamines
US6929747B2 (en) 2002-02-28 2005-08-16 Renesselaer Polytechnic Institute High-affinity, low-molecular-mass displacers for ion-exchange chromatography
US7214806B2 (en) * 2004-03-05 2007-05-08 Sachem, Inc. Synthetic multiple quaternary ammonium salts
CN101336124B (zh) * 2005-12-02 2012-06-13 塞克姆公司 阴离子交换顶替色谱法及在阴离子交换顶替色谱法中作为置换剂化合物的阴离子有机化合物

Also Published As

Publication number Publication date
JP4917611B2 (ja) 2012-04-18
TW200724235A (en) 2007-07-01
IL191200A (en) 2013-10-31
CN101346166A (zh) 2009-01-14
KR20080082613A (ko) 2008-09-11
WO2007055896A1 (en) 2007-05-18
DK1960077T3 (da) 2011-08-29
WO2007053235A1 (en) 2007-05-10
EP1960077B1 (de) 2011-05-18
EP1960077A1 (de) 2008-08-27
CN101346166B (zh) 2012-01-18
CA2628086A1 (en) 2007-05-18
TWI418406B (zh) 2013-12-11
US20100081844A1 (en) 2010-04-01
CA2628086C (en) 2011-04-05
ES2362234T3 (es) 2011-06-30
KR101299158B1 (ko) 2013-08-27
HK1126713A1 (en) 2009-09-11
US20070102363A1 (en) 2007-05-10
JP2009515164A (ja) 2009-04-09
US7632409B2 (en) 2009-12-15

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