ATE509920T1 - Quadratsäurederivate als inhibitoren von histondeacetylase - Google Patents

Quadratsäurederivate als inhibitoren von histondeacetylase

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Publication number
ATE509920T1
ATE509920T1 AT06807466T AT06807466T ATE509920T1 AT E509920 T1 ATE509920 T1 AT E509920T1 AT 06807466 T AT06807466 T AT 06807466T AT 06807466 T AT06807466 T AT 06807466T AT E509920 T1 ATE509920 T1 AT E509920T1
Authority
AT
Austria
Prior art keywords
histone deacetylase
inhibitors
acid derivatives
square acid
square
Prior art date
Application number
AT06807466T
Other languages
English (en)
Inventor
Emelen Kristof Van
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Application granted granted Critical
Publication of ATE509920T1 publication Critical patent/ATE509920T1/de

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/42—One nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • C—CHEMISTRY; METALLURGY
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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

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  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
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  • Dermatology (AREA)
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  • Immunology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Urology & Nephrology (AREA)
  • Psychiatry (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Oncology (AREA)
  • Endocrinology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
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AT06807466T 2005-10-27 2006-10-23 Quadratsäurederivate als inhibitoren von histondeacetylase ATE509920T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP05110080 2005-10-27
PCT/EP2006/067656 WO2007048767A1 (en) 2005-10-27 2006-10-23 Squaric acid derivatives as inhibitors of histone deacetylase

Publications (1)

Publication Number Publication Date
ATE509920T1 true ATE509920T1 (de) 2011-06-15

Family

ID=36192996

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06807466T ATE509920T1 (de) 2005-10-27 2006-10-23 Quadratsäurederivate als inhibitoren von histondeacetylase

Country Status (9)

Country Link
US (1) US7884105B2 (de)
EP (1) EP1943232B1 (de)
JP (1) JP5070214B2 (de)
AT (1) ATE509920T1 (de)
AU (1) AU2006307918B2 (de)
CA (1) CA2623360C (de)
DK (1) DK1943232T3 (de)
ES (1) ES2366132T3 (de)
WO (1) WO2007048767A1 (de)

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WO2007082880A1 (en) * 2006-01-19 2007-07-26 Janssen Pharmaceutica N.V. Pyridine and pyrimidine derivatives as inhibitors of histone deacetylase
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JP5070214B2 (ja) 2012-11-07
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CA2623360A1 (en) 2007-05-03
DK1943232T3 (da) 2011-08-29
ES2366132T3 (es) 2011-10-17
WO2007048767A1 (en) 2007-05-03
JP2009513599A (ja) 2009-04-02
US20080255140A1 (en) 2008-10-16
AU2006307918A1 (en) 2007-05-03
EP1943232B1 (de) 2011-05-18
US7884105B2 (en) 2011-02-08
AU2006307918B2 (en) 2012-06-21

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