ATE509938T1 - Makrolidverbindungen mit antiinflammatorischer wirkung - Google Patents

Makrolidverbindungen mit antiinflammatorischer wirkung

Info

Publication number: ATE509938T1
Authority: AT; Austria
Prior art keywords: macrolide compounds; inflammatory effect; macrolide; antiinflammatory activity; pharmaceutically acceptable
Prior art date: 2002-08-01

Application number

AT03750405T

Other languages

English (en)

Inventor

Mauro Napoletano

Ermanno Moriggi

Andrea Mereu

Fernando Ornaghi

Gabriele Morazzoni

Roberto Longoni

Carlo Riva

Luciano Pacchetti

Franco Pellacini

Original Assignee

Zambon Spa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-08-01

Filing date

2003-07-29

Publication date

2011-06-15

2003-07-29 Application filed by Zambon Spa filed Critical Zambon Spa

2011-06-15 Application granted granted Critical

2011-06-15 Publication of ATE509938T1 publication Critical patent/ATE509938T1/de

Links

230000003110 anti-inflammatory effect Effects 0.000 title abstract 3
239000003120 macrolide antibiotic agent Substances 0.000 title abstract 3
150000001875 compounds Chemical class 0.000 title abstract 2
YHVUVJYEERGYNU-UHFFFAOYSA-N 4',8-Di-Me ether-5,7,8-Trihydroxy-3-(4-hydroxybenzyl)-4-chromanone Natural products COC1(C)CC(O)OC(C)C1O YHVUVJYEERGYNU-UHFFFAOYSA-N 0.000 abstract 1
239000004480 active ingredient Substances 0.000 abstract 1
AJSDVNKVGFVAQU-BIIVOSGPSA-N cladinose Chemical group O=CC[C@@](C)(OC)[C@@H](O)[C@H](C)O AJSDVNKVGFVAQU-BIIVOSGPSA-N 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Genetics & Genomics (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
Biotechnology (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Bioinformatics & Cheminformatics (AREA)
Pulmonology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

AT03750405T 2002-08-01 2003-07-29 Makrolidverbindungen mit antiinflammatorischer wirkung ATE509938T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
IT001726A ITMI20021726A1 (it)	2002-08-01	2002-08-01	Macrolidi ad attivita' antiinfiammatoria.
PCT/EP2003/008448 WO2004013153A2 (en)	2002-08-01	2003-07-29	Macrolide compounds endowed with antiinflammatory activity

Publications (1)

Publication Number	Publication Date
ATE509938T1 true ATE509938T1 (de)	2011-06-15

Family

ID=31198615

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT03750405T ATE509938T1 (de)	2002-08-01	2003-07-29	Makrolidverbindungen mit antiinflammatorischer wirkung

Country Status (18)

Country	Link
US (2)	US7488811B2 (de)
EP (2)	EP1529053B1 (de)
JP (1)	JP4589110B2 (de)
KR (1)	KR101051369B1 (de)
CN (1)	CN100335491C (de)
AT (1)	ATE509938T1 (de)
AU (1)	AU2003269861B2 (de)
BR (1)	BR0313162A (de)
CA (1)	CA2493995C (de)
CO (1)	CO5720000A2 (de)
ES (1)	ES2364647T3 (de)
HR (1)	HRP20050195B1 (de)
IL (1)	IL166527A0 (de)
IT (1)	ITMI20021726A1 (de)
NZ (1)	NZ537992A (de)
PT (1)	PT1529053E (de)
RU (1)	RU2330856C2 (de)
WO (1)	WO2004013153A2 (de)

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ITMI20040124A1 (it) *	2004-01-29	2004-04-29	Zambon Spa	Macrolidi ad attivita' antiinfiammatoria
CN102816194A (zh) *	2004-02-27	2012-12-12	瑞伯-X医药品有限公司	大环化合物以及其制作和使用方法
CN108101948A (zh) *	2004-02-27	2018-06-01	瑞伯-X医药品有限公司	大环化合物以及其制作和使用方法
ATE419261T1 (de) *	2005-01-13	2009-01-15	Glaxosmithkline Zagreb	Decladinosyl-macrolide mit entzündungshemmender wirkung
US20080249034A1 (en) *	2005-03-21	2008-10-09	Zambon S.P.A.	Use of Macrolides for Treating Intestinal Inflammation
CN101291947B (zh)	2005-07-06	2012-08-22	萨宝公司	具有抗炎活性的大环内酯化合物的晶形
DK1934238T3 (en)	2005-08-24	2017-09-18	Melinta Therapeutics Inc	TRIAZOL COMPOUNDS AND METHODS FOR THE PREPARATION AND USE OF THESE
JP2009506063A (ja)	2005-08-24	2009-02-12	リブ−エックスファーマシューティカルズ，インコーポレイテッド	トリアゾール化合物ならびにこれを作製する方法および使用する方法
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US8124744B2 (en)	2006-05-01	2012-02-28	Taisho Pharmaceutical Co., Ltd.	Macrolide derivatives
WO2008106226A2 (en) *	2007-02-28	2008-09-04	Rib-X Pharmaceuticals, Inc.	Macrolide compounds and methods of making and using the same
AU2009218671B2 (en)	2008-02-08	2013-11-14	Basilea Pharmaceutica Ag	New macrolides and their use
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PE20120220A1 (es)	2009-01-30	2012-04-04	Glaxo Group Ltd	Macrolido anti-inflamatorio
JP2012516305A (ja) *	2009-01-30	2012-07-19	グラクソグループリミテッド	好中球優位の炎症性疾患の治療のための９−デオキソ−９ａ−メチル−９ａ−アザ−９ａ−ホモエリスロマイシンａ誘導体
CA2769551A1 (en)	2009-08-13	2011-02-17	Basilea Pharmaceutica Ag	New macrolides and their use
WO2011131749A1 (en)	2010-04-23	2011-10-27	Glaxo Group Limited	New 14 and 15 membered macrolides for the treatment of neutrophil dominated inflammatory diseases
EA201590788A1 (ru)	2012-11-07	2015-12-30	Тева Фармасьютикал Индастриз Лтд.	Аминные соли лахинимода
SG11201506409RA (en)	2013-03-14	2015-09-29	Teva Pharma	Crystals of laquinimod sodium and improved process for the manufacture thereof
EP2984087A1 (de) *	2013-04-10	2016-02-17	Probiotic Pharmaceuticals APS	Antimikrobielle azithromycinderivate mit nicht-antibiotischer pharmazeutischer wirkung
GB201608236D0 (en)	2016-05-11	2016-06-22	Fidelta D O O	Seco macrolide compounds
EP4051687A4 (de) *	2020-01-08	2022-12-21	Beijing Continent Pharmaceuticals Co., Ltd.	Makrolidverbindung und ihre verwendung zur behandlung von chronischer atemwegserkrankung

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DK0941998T3 (da)	1998-03-03	2004-09-20	Pfizer Prod Inc	3,6-ketalmakrolidantibiotika
IT1306205B1 (it) *	1999-01-15	2001-05-30	Zambon Spa	Macrolidi ad attivita' antiinfiammatoria.
DE19910159A1 (de)	1999-02-26	2000-09-14	Rosemarie Heis	Spezifische lgY-Eidotterantikörper, ihre Gewinnung und ihre Verwendung
JP2000351793A (ja) *	1999-06-09	2000-12-19	Hokuriku Seiyaku Co Ltd	エリスロマイシン誘導体
US6437106B1 (en) *	1999-06-24	2002-08-20	Abbott Laboratories	Process for preparing 6-o-substituted erythromycin derivatives
JP2001181294A (ja) *	1999-12-27	2001-07-03	Hokuriku Seiyaku Co Ltd	エリスロマイシン誘導体
ITMI20021726A1 (it) *	2002-08-01	2004-02-02	Zambon Spa	Macrolidi ad attivita' antiinfiammatoria.
ITMI20022292A1 (it) *	2002-10-29	2004-04-30	Zambon Spa	9a-azalidi ad attivita' antiinfiammatoria.
US20060043226A1 (en) *	2004-08-24	2006-03-02	Keith Roozeboom	Apparatus and method for grinding with staggered cutters
US7096915B2 (en) *	2004-11-05	2006-08-29	Hsiu-Man Yu Chen	Tape-roll supporting device

2002
- 2002-08-01 IT IT001726A patent/ITMI20021726A1/it unknown
2003
- 2003-07-29 PT PT03750405T patent/PT1529053E/pt unknown
- 2003-07-29 RU RU2005105592/04A patent/RU2330856C2/ru not_active IP Right Cessation
- 2003-07-29 WO PCT/EP2003/008448 patent/WO2004013153A2/en not_active Ceased
- 2003-07-29 JP JP2004525393A patent/JP4589110B2/ja not_active Expired - Fee Related
- 2003-07-29 BR BR0313162-9A patent/BR0313162A/pt not_active IP Right Cessation
- 2003-07-29 US US10/522,671 patent/US7488811B2/en not_active Expired - Fee Related
- 2003-07-29 EP EP03750405A patent/EP1529053B1/de not_active Expired - Lifetime
- 2003-07-29 ES ES03750405T patent/ES2364647T3/es not_active Expired - Lifetime
- 2003-07-29 EP EP10180640A patent/EP2258708A1/de not_active Withdrawn
- 2003-07-29 KR KR1020057001887A patent/KR101051369B1/ko not_active Expired - Fee Related
- 2003-07-29 AU AU2003269861A patent/AU2003269861B2/en not_active Ceased
- 2003-07-29 CN CNB038210533A patent/CN100335491C/zh not_active Expired - Fee Related
- 2003-07-29 AT AT03750405T patent/ATE509938T1/de active
- 2003-07-29 HR HRP20050195AA patent/HRP20050195B1/hr not_active IP Right Cessation
- 2003-07-29 CA CA2493995A patent/CA2493995C/en not_active Expired - Fee Related
- 2003-07-29 NZ NZ537992A patent/NZ537992A/en not_active IP Right Cessation
2005
- 2005-01-27 IL IL16652705A patent/IL166527A0/xx not_active IP Right Cessation
- 2005-02-28 CO CO05018584A patent/CO5720000A2/es active IP Right Grant
2008
- 2008-10-28 US US12/259,335 patent/US7704960B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
CA2493995A1 (en)	2004-02-12
KR20050037567A (ko)	2005-04-22
ES2364647T3 (es)	2011-09-08
RU2005105592A (ru)	2005-08-27
JP4589110B2 (ja)	2010-12-01
CN100335491C (zh)	2007-09-05
WO2004013153A2 (en)	2004-02-12
NZ537992A (en)	2007-11-30
US20060058246A1 (en)	2006-03-16
AU2003269861B2 (en)	2010-01-21
HRP20050195A2 (en)	2005-12-31
KR101051369B1 (ko)	2011-07-22
ITMI20021726A1 (it)	2004-02-02
HRP20050195B1 (hr)	2013-10-25
IL166527A0 (en)	2006-01-15
US7704960B2 (en)	2010-04-27
EP1529053A2 (de)	2005-05-11
EP1529053B1 (de)	2011-05-18
US20090054357A1 (en)	2009-02-26
BR0313162A (pt)	2005-07-05
CA2493995C (en)	2011-01-04
JP2005538998A (ja)	2005-12-22
WO2004013153A3 (en)	2004-04-08
US7488811B2 (en)	2009-02-10
AU2003269861A1 (en)	2004-02-23
PT1529053E (pt)	2011-07-05
CN1678620A (zh)	2005-10-05
RU2330856C2 (ru)	2008-08-10
EP2258708A1 (de)	2010-12-08
CO5720000A2 (es)	2007-01-31

Legal Events

Date

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Title

Description

2011-12-15

UEP

Publication of translation of european patent specification

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Publication	Publication Date	Title
ATE509938T1 (de)	2011-06-15	Makrolidverbindungen mit antiinflammatorischer wirkung
NO2025027I1 (no)	2025-06-13	Pharmaceutical mixture or association that includes as active ingredients: (1) ceftazidime or a salt thereof, and (2) avibactam or a pharmaceutically acceptable salt thereof - forlenget.
ATE319729T1 (de)	2006-03-15	9a-azalide mit entzündungshemmender wirkung
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