ATE510021T1 - Verfahren zur oxidation von terpenen - Google Patents
Verfahren zur oxidation von terpenenInfo
- Publication number
- ATE510021T1 ATE510021T1 AT99956167T AT99956167T ATE510021T1 AT E510021 T1 ATE510021 T1 AT E510021T1 AT 99956167 T AT99956167 T AT 99956167T AT 99956167 T AT99956167 T AT 99956167T AT E510021 T1 ATE510021 T1 AT E510021T1
- Authority
- AT
- Austria
- Prior art keywords
- sub
- mutant
- cells
- amino acid
- oxidizing
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 4
- 235000007586 terpenes Nutrition 0.000 title abstract 2
- 230000003647 oxidation Effects 0.000 title 1
- 238000007254 oxidation reaction Methods 0.000 title 1
- 150000003505 terpenes Chemical class 0.000 title 1
- 102000004190 Enzymes Human genes 0.000 abstract 3
- 108090000790 Enzymes Proteins 0.000 abstract 3
- 150000001413 amino acids Chemical class 0.000 abstract 2
- 230000001590 oxidative effect Effects 0.000 abstract 2
- 125000002015 acyclic group Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- -1 cyclic terpene Chemical class 0.000 abstract 1
- 150000001925 cycloalkenes Chemical class 0.000 abstract 1
- 150000003278 haem Chemical class 0.000 abstract 1
- 238000006467 substitution reaction Methods 0.000 abstract 1
- 239000000758 substrate Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
- C12N9/0077—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14) with a reduced iron-sulfur protein as one donor (1.14.15)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Peptides Or Proteins (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9825421.2A GB9825421D0 (en) | 1998-11-19 | 1998-11-19 | Process for oxidising terpenes |
| PCT/GB1999/003873 WO2000031273A2 (en) | 1998-11-19 | 1999-11-19 | Process for oxidising terpenes |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE510021T1 true ATE510021T1 (de) | 2011-06-15 |
Family
ID=10842737
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99956167T ATE510021T1 (de) | 1998-11-19 | 1999-11-19 | Verfahren zur oxidation von terpenen |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US7211420B1 (de) |
| EP (1) | EP1131440B1 (de) |
| JP (2) | JP4886930B2 (de) |
| AT (1) | ATE510021T1 (de) |
| AU (1) | AU1281900A (de) |
| GB (1) | GB9825421D0 (de) |
| WO (1) | WO2000031273A2 (de) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9914373D0 (en) | 1999-06-18 | 1999-08-18 | Isis Innovation | Process for oxidising aromatic compounds |
| MY126592A (en) * | 1999-07-27 | 2006-10-31 | Basf Ag | Novel cytochrome p450 monooxygenases and their use for the oxidation of organic compounds |
| ATE342351T1 (de) | 1999-07-27 | 2006-11-15 | Basf Ag | Elektronendonorsystem für enzyme und dessen anwendung bei der biochemischen umsetzung von substraten |
| GB0002201D0 (en) * | 2000-01-31 | 2000-03-22 | Imperial College | Process |
| WO2002083868A2 (en) | 2001-04-16 | 2002-10-24 | California Institute Of Technology | Peroxide-driven cytochrome p450 oxygenase variants |
| US7226768B2 (en) | 2001-07-20 | 2007-06-05 | The California Institute Of Technology | Cytochrome P450 oxygenases |
| EP1639091B1 (de) | 2003-06-17 | 2012-12-05 | California University Of Technology | Regio- und enantioselektive Alkanhydroxylierung mit modifiziertem Cytochrom p450 |
| EP1660646B1 (de) | 2003-08-11 | 2014-12-31 | California Institute Of Technology | Temperaturstabile peroxidgetriebene cytochrom-p450-oxygenase-varianten und verwendungsverfahren |
| US8715988B2 (en) | 2005-03-28 | 2014-05-06 | California Institute Of Technology | Alkane oxidation by modified hydroxylases |
| US11214817B2 (en) | 2005-03-28 | 2022-01-04 | California Institute Of Technology | Alkane oxidation by modified hydroxylases |
| US8252559B2 (en) | 2006-08-04 | 2012-08-28 | The California Institute Of Technology | Methods and systems for selective fluorination of organic molecules |
| US8026085B2 (en) | 2006-08-04 | 2011-09-27 | California Institute Of Technology | Methods and systems for selective fluorination of organic molecules |
| US8101399B2 (en) | 2006-12-12 | 2012-01-24 | The Regents Of The University Of California | Artemisinic epoxide and methods for producing same |
| US8802401B2 (en) | 2007-06-18 | 2014-08-12 | The California Institute Of Technology | Methods and compositions for preparation of selectively protected carbohydrates |
| GB0719620D0 (en) | 2007-10-08 | 2007-11-14 | Isis Innovation | Mutant Enzymes |
| WO2010019489A2 (en) * | 2008-08-13 | 2010-02-18 | Salk Institute For Biological Studies | Method for making terpene derivatives |
| US9322007B2 (en) | 2011-07-22 | 2016-04-26 | The California Institute Of Technology | Stable fungal Cel6 enzyme variants |
| ES2625861T3 (es) * | 2011-11-01 | 2017-07-20 | Firmenich Sa | Citocromo p450 y su uso para la oxidación enzimática de terpenos |
| TR201910573T4 (tr) * | 2012-08-31 | 2019-08-21 | Glaxosmithkline Biologicals Sa | Staphylococcus aureus'a karşı bağışıklık kazandırmak için stabilize edilmiş proteinler. |
| EP3125933B1 (de) * | 2014-03-31 | 2022-05-18 | Boehringer Ingelheim Vetmedica GmbH | Verbesserte modulare antigentransportmoleküle und verwendung davon |
| CN107002109A (zh) | 2014-08-21 | 2017-08-01 | 马努斯生物合成股份有限公司 | 含氧萜烯的生产方法 |
| CN107896481B (zh) | 2015-05-18 | 2021-07-06 | 齐姆特罗尼克斯公司 | 磁力固定化的杀微生物酶 |
| WO2018034877A1 (en) | 2016-08-13 | 2018-02-22 | Zymtronix, Llc | Magnetically immobilized biocidal enzymes and biocidal chemicals |
| CA3045640A1 (en) * | 2016-12-03 | 2018-06-07 | Zymtronix Catalytic Systems, Inc. | Magnetically immobilized metabolic enzymes and cofactor systems |
| EP3858986A1 (de) | 2020-02-03 | 2021-08-04 | Bayer Aktiengesellschaft | P450-bm3-monooxygenase-varianten zur c19-hydroxylierung von steroiden |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB334841A (en) | 1929-06-04 | 1930-09-04 | John Pinder | Theft alarm or signal for use on motor vehicles |
| DE3629890A1 (de) | 1986-08-29 | 1988-03-10 | Schering Ag | Mikroorganismen und plasmide fuer die 2,4-dichlorphenoxyessigsaeure (2,4-d)-monooxigenase - bildung und verfahren zur herstellung dieser plasmide und staemme |
| FR2693207B1 (fr) | 1992-07-03 | 1994-09-30 | Orsan | Souche de levure permettant la co-expression d'une activité mono-oxygénase de cytochrome P450 hétérologue et d'une NADPH-cytochrome P450-réductase endogène ou hétérologue et son utilisation à des fins de bioconversion. |
| GB9422205D0 (en) * | 1994-11-03 | 1994-12-21 | British Gas Plc | Enzyme mutant and method |
| GB2306485B (en) | 1995-11-01 | 1998-12-09 | British Gas Plc | Enzyme mutant |
| NZ320497A (en) * | 1995-11-01 | 1999-09-29 | British Gas Plc | Mutant mono-oxygenase cytochrome p450cam |
| US5763237A (en) | 1996-05-21 | 1998-06-09 | Board Of Trustees Operating Michigan State University | Method for production of monoterpene derivatives of limonene |
-
1998
- 1998-11-19 GB GBGB9825421.2A patent/GB9825421D0/en not_active Ceased
-
1999
- 1999-11-19 WO PCT/GB1999/003873 patent/WO2000031273A2/en not_active Ceased
- 1999-11-19 EP EP99956167A patent/EP1131440B1/de not_active Expired - Lifetime
- 1999-11-19 AT AT99956167T patent/ATE510021T1/de not_active IP Right Cessation
- 1999-11-19 US US09/856,339 patent/US7211420B1/en not_active Expired - Lifetime
- 1999-11-19 JP JP2000584082A patent/JP4886930B2/ja not_active Expired - Lifetime
- 1999-11-19 AU AU12819/00A patent/AU1281900A/en not_active Abandoned
-
2011
- 2011-08-26 JP JP2011184705A patent/JP5611151B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| AU1281900A (en) | 2000-06-13 |
| JP4886930B2 (ja) | 2012-02-29 |
| EP1131440B1 (de) | 2011-05-18 |
| JP2002530112A (ja) | 2002-09-17 |
| JP2012010707A (ja) | 2012-01-19 |
| EP1131440A2 (de) | 2001-09-12 |
| WO2000031273A2 (en) | 2000-06-02 |
| US7211420B1 (en) | 2007-05-01 |
| JP5611151B2 (ja) | 2014-10-22 |
| GB9825421D0 (en) | 1999-01-13 |
| WO2000031273A3 (en) | 2000-08-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |