ATE511516T1 - Gpr-146-rezeptor - Google Patents

Gpr-146-rezeptor

Info

Publication number
ATE511516T1
ATE511516T1 AT06794710T AT06794710T ATE511516T1 AT E511516 T1 ATE511516 T1 AT E511516T1 AT 06794710 T AT06794710 T AT 06794710T AT 06794710 T AT06794710 T AT 06794710T AT E511516 T1 ATE511516 T1 AT E511516T1
Authority
AT
Austria
Prior art keywords
seq
gpr146
receptor
gpr
dyslipidaemias
Prior art date
Application number
AT06794710T
Other languages
English (en)
Inventor
Johannes Grosse
Justin Powell
John Dixon
Rosemary Thresher
Kate Day
Original Assignee
Takeda Pharmaceutical
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Pharmaceutical filed Critical Takeda Pharmaceutical
Application granted granted Critical
Publication of ATE511516T1 publication Critical patent/ATE511516T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cardiology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Vascular Medicine (AREA)
  • Emergency Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Saccharide Compounds (AREA)
  • Peptides Or Proteins (AREA)
AT06794710T 2005-10-10 2006-10-10 Gpr-146-rezeptor ATE511516T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0520568.7A GB0520568D0 (en) 2005-10-10 2005-10-10 Receptor
PCT/GB2006/003759 WO2007042792A1 (en) 2005-10-10 2006-10-10 Gpr 146 receptor

Publications (1)

Publication Number Publication Date
ATE511516T1 true ATE511516T1 (de) 2011-06-15

Family

ID=35430110

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06794710T ATE511516T1 (de) 2005-10-10 2006-10-10 Gpr-146-rezeptor

Country Status (6)

Country Link
US (1) US20090036394A1 (de)
EP (1) EP1945661B1 (de)
JP (1) JP5064398B2 (de)
AT (1) ATE511516T1 (de)
GB (1) GB0520568D0 (de)
WO (1) WO2007042792A1 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN117180404A (zh) * 2023-10-24 2023-12-08 清华大学 Cholesin在调节胆固醇稳态中的用途
CN120866506A (zh) * 2024-04-30 2025-10-31 首都医科大学附属北京安贞医院 Gpr146作为靶点在制备治疗高血压药物中的应用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1171374A (en) 1981-04-13 1984-07-24 Takeda Chemical Industries, Ltd. Pseudo-aminosugars, their production and use
GB8607679D0 (en) 1986-03-27 1986-04-30 Winter G P Recombinant dna product
GB8823869D0 (en) 1988-10-12 1988-11-16 Medical Res Council Production of antibodies
US6075181A (en) 1990-01-12 2000-06-13 Abgenix, Inc. Human antibodies derived from immunized xenomice
DK0548165T3 (da) 1990-09-13 2001-07-16 Univ Duke Ekspression af G-proteinkoblede receptorer i gær
US20030027252A1 (en) * 2000-11-22 2003-02-06 Tularik, Inc. Novel receptors
EP1364024A2 (de) * 2000-11-27 2003-11-26 Arena Pharmaceuticals, Inc. Endogene und nicht-endogene, konstitutiv aktivierte menschliche g-protein gekoppelte rezeptoren
JPWO2003030936A1 (ja) * 2001-10-02 2005-01-20 住友製薬株式会社 生活習慣病又は拒食症治療薬及びそのスクリーニング方法
JP2008503212A (ja) * 2004-06-16 2008-02-07 メタボレックス インコーポレーティッド 肥満、糖尿病およびインスリン抵抗性の診断および治療の方法

Also Published As

Publication number Publication date
GB0520568D0 (en) 2005-11-16
EP1945661B1 (de) 2011-06-01
EP1945661A1 (de) 2008-07-23
WO2007042792A1 (en) 2007-04-19
JP2009511037A (ja) 2009-03-19
JP5064398B2 (ja) 2012-10-31
US20090036394A1 (en) 2009-02-05

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