ATE512154T1 - Kondensiertes pyrimidinderivat und xanthinoxidaseinhibitor - Google Patents

Kondensiertes pyrimidinderivat und xanthinoxidaseinhibitor

Info

Publication number
ATE512154T1
ATE512154T1 AT05751417T AT05751417T ATE512154T1 AT E512154 T1 ATE512154 T1 AT E512154T1 AT 05751417 T AT05751417 T AT 05751417T AT 05751417 T AT05751417 T AT 05751417T AT E512154 T1 ATE512154 T1 AT E512154T1
Authority
AT
Austria
Prior art keywords
xanthine
oxidasine
inhibitor
pyrimidine derivative
carbon atoms
Prior art date
Application number
AT05751417T
Other languages
English (en)
Inventor
Shinichi Yoshida
Kunio Kobayashi
Nobutaka Mochiduki
Tomio Yamakawa
Tadashi Kobayashi
Yoriko Shinohara
Original Assignee
Nippon Chemiphar Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nippon Chemiphar Co filed Critical Nippon Chemiphar Co
Application granted granted Critical
Publication of ATE512154T1 publication Critical patent/ATE512154T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT05751417T 2004-06-14 2005-06-13 Kondensiertes pyrimidinderivat und xanthinoxidaseinhibitor ATE512154T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2004175798 2004-06-14
PCT/JP2005/011188 WO2005121153A1 (ja) 2004-06-14 2005-06-13 縮合ピリミジン誘導体、及びキサンチンオキシダーゼ阻害剤

Publications (1)

Publication Number Publication Date
ATE512154T1 true ATE512154T1 (de) 2011-06-15

Family

ID=35503006

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05751417T ATE512154T1 (de) 2004-06-14 2005-06-13 Kondensiertes pyrimidinderivat und xanthinoxidaseinhibitor

Country Status (10)

Country Link
US (1) US7598254B2 (de)
EP (1) EP1757610B1 (de)
JP (3) JP4914210B2 (de)
CN (1) CN1993367B (de)
AT (1) ATE512154T1 (de)
DK (1) DK1757610T3 (de)
ES (1) ES2367118T3 (de)
PL (1) PL1757610T3 (de)
PT (1) PT1757610E (de)
WO (1) WO2005121153A1 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1757610T3 (da) * 2004-06-14 2011-08-01 Nippon Chemiphar Co Kondenseret pyrimidinderivat og xanthinoxidaseinhibitor
WO2007004688A1 (ja) * 2005-07-01 2007-01-11 Nippon Chemiphar Co., Ltd. キサンチンオキシダーゼ阻害剤
KR20140037954A (ko) 2006-06-22 2014-03-27 닛뽕 케미파 가부시키가이샤 항암제 내성 극복제
WO2014065275A1 (ja) 2012-10-23 2014-05-01 国立大学法人福井大学 腫瘍融解症候群の治療薬及び予防薬
CN103848798B (zh) 2012-11-30 2016-01-06 镇江新元素医药科技有限公司 2-芳基硒唑化合物及其药物组合物
CN105579037A (zh) * 2013-05-31 2016-05-11 武田制药美国有限公司 用黄嘌呤氧化酶抑制剂治疗的方法和含黄嘌呤氧化酶抑制剂的组合物
US10413546B2 (en) 2015-02-24 2019-09-17 National University Corporation Tottori University Drug for preventing and/or treating dementia
TWI780270B (zh) * 2017-11-28 2022-10-11 靜岡縣公立大學法人 固體分散體
JP2021127289A (ja) * 2018-04-27 2021-09-02 日本ケミファ株式会社 縮合ピリミジン誘導体
WO2020246526A1 (ja) 2019-06-04 2020-12-10 日本ケミファ株式会社 キサンチンオキシダーゼ阻害剤含有腸溶性製剤
WO2020246528A1 (ja) 2019-06-04 2020-12-10 日本ケミファ株式会社 痛風又は高尿酸血症の治療薬
CN121648131A (zh) 2020-12-08 2026-03-13 学校法人东日本学园 细胞内atp增强剂
CN116640095A (zh) * 2023-04-19 2023-08-25 山东大学 一种含脂肪羧基的二芳基胺类衍生物及其制备方法与应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6421431A (en) 1987-07-16 1989-01-24 Fuji Photo Film Co Ltd Film carrying device
JP2691317B2 (ja) * 1989-08-25 1997-12-17 株式会社大塚製薬工場 ４―ヒドロキシ―８―（３―低級アルコキシ―４―フェニルスルフィニルフェニル）ピラゾロ〔１，５―ａ〕―１，３，５―トリアジン光学活性体の塩類及びその製造方法
ES2092580T3 (es) * 1990-11-30 1996-12-01 Teijin Ltd Derivado de 2-ariltiazol y composicion farmaceutica que contiene el mismo.
ID21775A (id) 1996-10-25 1999-07-22 Yoshitomi Pharmaceutical Senyawa-senyawa 1-fenilpirazol dan penggunaan farmasinya
JP2000001431A (ja) * 1998-06-15 2000-01-07 Kotobuki Seiyaku Kk 尿酸排泄剤
CN101092400A (zh) 2001-11-16 2007-12-26 日本化学医药株式会社 黄嘌呤氧化酶抑制剂
DK1757610T3 (da) * 2004-06-14 2011-08-01 Nippon Chemiphar Co Kondenseret pyrimidinderivat og xanthinoxidaseinhibitor

Also Published As

Publication number Publication date
JP4914210B2 (ja) 2012-04-11
CN1993367A (zh) 2007-07-04
JP5456757B2 (ja) 2014-04-02
DK1757610T3 (da) 2011-08-01
EP1757610B1 (de) 2011-06-08
US7598254B2 (en) 2009-10-06
JP2012092128A (ja) 2012-05-17
CN1993367B (zh) 2012-05-30
EP1757610A1 (de) 2007-02-28
US20070293512A1 (en) 2007-12-20
EP1757610A4 (de) 2009-06-24
ES2367118T3 (es) 2011-10-28
JPWO2005121153A1 (ja) 2008-04-10
JP5554439B2 (ja) 2014-07-23
PL1757610T3 (pl) 2011-10-31
WO2005121153A1 (ja) 2005-12-22
PT1757610E (pt) 2011-08-24
JP2013189460A (ja) 2013-09-26

Similar Documents

Publication Publication Date Title
DK1452528T3 (da) Xanthinoxidaserinhibitorer
ATE512154T1 (de) Kondensiertes pyrimidinderivat und xanthinoxidaseinhibitor
WO2006062984A3 (en) Inhibitors of protein kinases
DE602006007012D1 (de) Pyridinderivate als dipeptedyl-peptidase-hemmer
ATE449099T1 (de) Derivate des 2-trifluormethyl-6-aminopurins als phosphodiesterase 4 inhibitoren
WO2007026920A3 (en) Amide derivatives as rock inhibitors
BR0013041A (pt) Composto heterociclico e composição farmacêutica para tratar e prevenir doenças mediadas por cgmp-pde, seu uso e método
WO2006062982A3 (en) Urea inhibitors of map kinases
NO20073791L (no) Pyrazolylaminopyridinderivater anvendbare som kinaseinhibitorer
PE20080835A1 (es) Derivados novedosos de aminopiridina que tienen accion inhibidora selectiva sobre aurora a
ATE253545T1 (de) Biarylessigsäure-derivate und ihre verwendung als cox-2 inhibitoren
CY1111922T1 (el) 1-ετεροκυκλυλσουλφονυλ, 2-αμινομεθυλ, 5-(ετερο-)αρυλ υποκατεστημενα 1-η-πυρρολιου παραγωγα ως αναστολεις εκκρισης οξεος
ATE388146T1 (de) 1-isopropyl-2-oxo-1,2-dihydropyridin-3- carbonsäureamidderivate mit agonistischer wirkung am 5-ht4-rezeptor
ATE540928T1 (de) Isochinolinverbindungen und ihre medizinische verwendung
WO2008076779A3 (en) 2-(piperidin-4-yl0xy)pyrimidin-4-amine derivatives as deoxycytidine kinase inhibitors for the treatment of cancer
WO2008126901A1 (ja) 含窒素複素環化合物およびそれを含有する医薬組成物
PE20011115A1 (es) Etanos tri-aril-sustituidos inhibidores de pde4
WO2006123165A3 (en) Pyrimidine derivatives as hsp90 inhibitors
ATE172452T1 (de) Bicyclische stichstoff enthaltende derivate als prolyl-endopeptidase inhibitoren
EA200701779A1 (ru) Производные (1,5-дифенил-1н-пиразол-3-ил)оксадиазола, их получение и их применение в терапии
EA200600018A1 (ru) Производные никотинамида, полезные в качестве ингибиторов фдэ4
WO2005009965A8 (en) Nicotinamide derivatives useful as pde4 inhibitors
ATE445619T1 (de) Pyridinylpyrazolopyrimidinon-derivate als pde 7 inhibitoren
EA200700758A1 (ru) Новые производные бис-азаиндолов, их получение и фармацевтическое применение в качестве ингибиторов киназ
WO2007081690A3 (en) Inhibitors of protein kinases

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 1757610

Country of ref document: EP