ATE512154T1 - Kondensiertes pyrimidinderivat und xanthinoxidaseinhibitor - Google Patents

Kondensiertes pyrimidinderivat und xanthinoxidaseinhibitor

Info

Publication number: ATE512154T1
Authority: AT; Austria
Prior art keywords: xanthine; oxidasine; inhibitor; pyrimidine derivative; carbon atoms
Prior art date: 2004-06-14

Application number

AT05751417T

Other languages

English (en)

Inventor

Shinichi Yoshida

Kunio Kobayashi

Nobutaka Mochiduki

Tomio Yamakawa

Tadashi Kobayashi

Yoriko Shinohara

Original Assignee

Nippon Chemiphar Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2004-06-14

Filing date

2005-06-13

Publication date

2011-06-15

2005-06-13 Application filed by Nippon Chemiphar Co filed Critical Nippon Chemiphar Co

2011-06-15 Application granted granted Critical

2011-06-15 Publication of ATE512154T1 publication Critical patent/ATE512154T1/de

Links

LRFVTYWOQMYALW-UHFFFAOYSA-N 9H-xanthine Chemical compound O=C1NC(=O)NC2=C1NC=N2 LRFVTYWOQMYALW-UHFFFAOYSA-N 0.000 title 2
CZPWVGJYEJSRLH-UHFFFAOYSA-N Pyrimidine Chemical class C1=CN=CN=C1 CZPWVGJYEJSRLH-UHFFFAOYSA-N 0.000 title 1
239000003112 inhibitor Substances 0.000 title 1
229940075420 xanthine Drugs 0.000 title 1
125000004432 carbon atom Chemical group C* 0.000 abstract 3
NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical group [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 2
QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical group [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 2
150000001875 compounds Chemical class 0.000 abstract 2
125000004093 cyano group Chemical group *C#N 0.000 abstract 2
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 2
229910052760 oxygen Inorganic materials 0.000 abstract 2
239000001301 oxygen Substances 0.000 abstract 2
229910052717 sulfur Inorganic materials 0.000 abstract 2
239000011593 sulfur Chemical group 0.000 abstract 2
229940123769 Xanthine oxidase inhibitor Drugs 0.000 abstract 1
125000003545 alkoxy group Chemical group 0.000 abstract 1
125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 1
125000000217 alkyl group Chemical group 0.000 abstract 1
125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
229910052736 halogen Inorganic materials 0.000 abstract 1
150000002367 halogens Chemical class 0.000 abstract 1
125000001624 naphthyl group Chemical group 0.000 abstract 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
125000004076 pyridyl group Chemical group 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
125000001424 substituent group Chemical group 0.000 abstract 1
239000003064 xanthine oxidase inhibitor Chemical group 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
Diabetes (AREA)
Hematology (AREA)
Obesity (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Physical Education & Sports Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Plural Heterocyclic Compounds (AREA)

AT05751417T 2004-06-14 2005-06-13 Kondensiertes pyrimidinderivat und xanthinoxidaseinhibitor ATE512154T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP2004175798		2004-06-14
PCT/JP2005/011188 WO2005121153A1 (ja)	2004-06-14	2005-06-13	縮合ピリミジン誘導体、及びキサンチンオキシダーゼ阻害剤

Publications (1)

Publication Number	Publication Date
ATE512154T1 true ATE512154T1 (de)	2011-06-15

Family

ID=35503006

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT05751417T ATE512154T1 (de)	2004-06-14	2005-06-13	Kondensiertes pyrimidinderivat und xanthinoxidaseinhibitor

Country Status (10)

Country	Link
US (1)	US7598254B2 (de)
EP (1)	EP1757610B1 (de)
JP (3)	JP4914210B2 (de)
CN (1)	CN1993367B (de)
AT (1)	ATE512154T1 (de)
DK (1)	DK1757610T3 (de)
ES (1)	ES2367118T3 (de)
PL (1)	PL1757610T3 (de)
PT (1)	PT1757610E (de)
WO (1)	WO2005121153A1 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
PL1757610T3 (pl) *	2004-06-14	2011-10-31	Nippon Chemiphar Co	Skondensowana pochodna pirymidyny oraz inhibitor oksydazy ksantynowej
KR20080035594A (ko) *	2005-07-01	2008-04-23	닛뽕 케미파 가부시키가이샤	크산틴옥시다아제 저해제
KR20090031744A (ko)	2006-06-22	2009-03-27	닛뽕 케미파 가부시키가이샤	항암제 내성 극복제
EP2913053A4 (de)	2012-10-23	2016-05-25	Teijin Pharma Ltd	Therapeutischer oder prophylaktischer wirkstoff gegen tumorlyse-syndrom
CN103848798B (zh)	2012-11-30	2016-01-06	镇江新元素医药科技有限公司	2-芳基硒唑化合物及其药物组合物
MX2015016494A (es)	2013-05-31	2016-11-18	Takeda Pharmaceuticals Usa Inc	Métodos de tratamiento y composiciones con inhibidores de xantina oxidasa.
WO2016136727A1 (ja) *	2015-02-24	2016-09-01	国立大学法人鳥取大学	認知症の予防及び／又は治療のための医薬
TWI780270B (zh) *	2017-11-28	2022-10-11	靜岡縣公立大學法人	固體分散體
JP2021127289A (ja) *	2018-04-27	2021-09-02	日本ケミファ株式会社	縮合ピリミジン誘導体
CN113924145A (zh) *	2019-06-04	2022-01-11	日本化学药品株式会社	痛风或高尿酸血症的治疗药
US20220323442A1 (en) *	2019-06-04	2022-10-13	Nippon Chemiphar Co., Ltd.	Enteric-coated preparation comprising xanthine oxidase inhibitor
KR20230118083A (ko)	2020-12-08	2023-08-10	학교법인 히가시-니뽄-가쿠엔	세포 내 atp 증강제
CN116640095A (zh) *	2023-04-19	2023-08-25	山东大学	一种含脂肪羧基的二芳基胺类衍生物及其制备方法与应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS6421431A (en)	1987-07-16	1989-01-24	Fuji Photo Film Co Ltd	Film carrying device
JP2691317B2 (ja) *	1989-08-25	1997-12-17	株式会社大塚製薬工場	４―ヒドロキシ―８―（３―低級アルコキシ―４―フェニルスルフィニルフェニル）ピラゾロ〔１，５―ａ〕―１，３，５―トリアジン光学活性体の塩類及びその製造方法
DE122008000051I1 (de) *	1990-11-30	2009-02-05	Teijin Ltd	2-arylthiazolderivat sowie dieses enthaltendes arzneimittel
ID21775A (id)	1996-10-25	1999-07-22	Yoshitomi Pharmaceutical	Senyawa-senyawa 1-fenilpirazol dan penggunaan farmasinya
JP2000001431A (ja) *	1998-06-15	2000-01-07	Kotobuki Seiyaku Kk	尿酸排泄剤
US7253154B2 (en) *	2001-11-16	2007-08-07	Nippon Chemiphar Co., Ltd.	Substituted thiazolopyrimidines as xanthine oxidase inhibitors
PL1757610T3 (pl) *	2004-06-14	2011-10-31	Nippon Chemiphar Co	Skondensowana pochodna pirymidyny oraz inhibitor oksydazy ksantynowej

2005
- 2005-06-13 PL PL05751417T patent/PL1757610T3/pl unknown
- 2005-06-13 US US11/629,277 patent/US7598254B2/en active Active
- 2005-06-13 ES ES05751417T patent/ES2367118T3/es not_active Expired - Lifetime
- 2005-06-13 PT PT05751417T patent/PT1757610E/pt unknown
- 2005-06-13 EP EP05751417A patent/EP1757610B1/de not_active Expired - Lifetime
- 2005-06-13 WO PCT/JP2005/011188 patent/WO2005121153A1/ja not_active Ceased
- 2005-06-13 AT AT05751417T patent/ATE512154T1/de active
- 2005-06-13 DK DK05751417.6T patent/DK1757610T3/da active
- 2005-06-13 JP JP2006514620A patent/JP4914210B2/ja not_active Expired - Fee Related
- 2005-06-13 CN CN2005800267399A patent/CN1993367B/zh not_active Expired - Lifetime
2011
- 2011-12-16 JP JP2011276232A patent/JP5456757B2/ja not_active Expired - Fee Related
2013
- 2013-06-03 JP JP2013117370A patent/JP5554439B2/ja not_active Expired - Fee Related

Also Published As

Publication number	Publication date
EP1757610A1 (de)	2007-02-28
CN1993367B (zh)	2012-05-30
CN1993367A (zh)	2007-07-04
ES2367118T3 (es)	2011-10-28
WO2005121153A1 (ja)	2005-12-22
US7598254B2 (en)	2009-10-06
EP1757610A4 (de)	2009-06-24
JP2013189460A (ja)	2013-09-26
PT1757610E (pt)	2011-08-24
JP2012092128A (ja)	2012-05-17
JP5456757B2 (ja)	2014-04-02
US20070293512A1 (en)	2007-12-20
JP5554439B2 (ja)	2014-07-23
EP1757610B1 (de)	2011-06-08
JPWO2005121153A1 (ja)	2008-04-10
DK1757610T3 (da)	2011-08-01
JP4914210B2 (ja)	2012-04-11
PL1757610T3 (pl)	2011-10-31

Legal Events

Date

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Title

Description

2012-01-15

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Publication of translation of european patent specification

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