ATE512217T1 - 5-substituerte hydantoin racemase, dafür kodierende dna, und verfahren zur herstellung optisch aktiver aminosäure - Google Patents

5-substituerte hydantoin racemase, dafür kodierende dna, und verfahren zur herstellung optisch aktiver aminosäure

Info

Publication number
ATE512217T1
ATE512217T1 AT01119275T AT01119275T ATE512217T1 AT E512217 T1 ATE512217 T1 AT E512217T1 AT 01119275 T AT01119275 T AT 01119275T AT 01119275 T AT01119275 T AT 01119275T AT E512217 T1 ATE512217 T1 AT E512217T1
Authority
AT
Austria
Prior art keywords
amino acid
optically active
dna coding
substituted hydantoin
active amino
Prior art date
Application number
AT01119275T
Other languages
English (en)
Inventor
Shunichi Suzuki
Norimasa Onishi
Kenzo Yokozeki
Original Assignee
Ajinomoto Kk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ajinomoto Kk filed Critical Ajinomoto Kk
Application granted granted Critical
Publication of ATE512217T1 publication Critical patent/ATE512217T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/22—Tryptophan; Tyrosine; Phenylalanine; 3,4-Dihydroxyphenylalanine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/90—Isomerases (5.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/006—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures
    • C12P41/009—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures by reactions involving hydantoins or carbamoylamino compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Analytical Chemistry (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT01119275T 2000-09-13 2001-08-09 5-substituerte hydantoin racemase, dafür kodierende dna, und verfahren zur herstellung optisch aktiver aminosäure ATE512217T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2000278571 2000-09-13
JP2001065815 2001-03-08

Publications (1)

Publication Number Publication Date
ATE512217T1 true ATE512217T1 (de) 2011-06-15

Family

ID=26599920

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01119275T ATE512217T1 (de) 2000-09-13 2001-08-09 5-substituerte hydantoin racemase, dafür kodierende dna, und verfahren zur herstellung optisch aktiver aminosäure

Country Status (4)

Country Link
US (3) US6815195B2 (de)
EP (1) EP1188826B1 (de)
AT (1) ATE512217T1 (de)
SG (1) SG109959A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4529338B2 (ja) * 2001-03-08 2010-08-25 味の素株式会社 ヒダントイナーゼをコードするｄｎａ、ｎ−カルバミル−ｌ−アミノ酸ハイドロラーゼをコードするｄｎａ、組み換えｄｎａ、形質転換された細胞、タンパク質の製造方法および光学活性アミノ酸の製造方法
WO2003085108A1 (fr) * 2002-04-10 2003-10-16 Ajinomoto Co., Inc. Adn recombinant presentant un gene d'hydantoinase et un gene de carbamylase et procede de production d'acide amine
WO2003100050A1 (en) 2002-05-23 2003-12-04 Dsm Ip Assets B.V. Hydantoin racemase
DE10234764A1 (de) * 2002-07-30 2004-02-19 Degussa Ag Verfahren zur Herstellung von enantiomerenangereichertem tert.-Leucin
WO2004111227A2 (en) * 2003-06-06 2004-12-23 Degussa Ag Screening process for hydantoin racemases
JP4452914B2 (ja) 2003-09-08 2010-04-21 味の素株式会社 新規トランスポータタンパク質
US7709235B2 (en) * 2005-01-31 2010-05-04 Kaneka Corporation 5-Substituted hydantoin racemase, DNA encoding the same, recombinant DNA, transformed cell, and process for production of optically active N-carbamylamino acid or optically active amino acid
US8217027B2 (en) * 2006-12-21 2012-07-10 Abbott Laboratories Sphingosine-1-phosphate receptor agonist and antagonist compounds
JP2010513531A (ja) * 2006-12-21 2010-04-30 アボット・ラボラトリーズ １−アミノ、３−置換フェニルシクロペンタンカルボン酸エステルの個々の立体異性体の製造および単離方法
WO2011003702A1 (en) 2009-07-09 2011-01-13 Dsm Ip Assets B.V. Stabilized enzyme compositions

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4016037A (en) 1975-10-15 1977-04-05 Ajinomoto Co., Inc. Method for producing L-amino acid
JPS5810074B2 (ja) 1979-07-18 1983-02-24 味の素株式会社 新規微生物
JPS62122591A (ja) 1985-11-25 1987-06-03 Denki Kagaku Kogyo Kk 光学活性５−置換ヒダントイン類のラセミ化方法
DE4316928C2 (de) * 1993-05-19 1995-03-16 Degussa Neue Mikroorganismen, deren Verwendung und Verfahren zur Herstellung von L-alpha-Aminosäuren
DE19519717C1 (de) 1995-05-30 1996-08-22 Degussa Neuer Mikroorganismus, dessen Verwendung und Verfahren zur Herstellung von L-alpha-Aminosäuren
US6551795B1 (en) * 1998-02-18 2003-04-22 Genome Therapeutics Corporation Nucleic acid and amino acid sequences relating to pseudomonas aeruginosa for diagnostics and therapeutics
AU7513400A (en) * 1999-09-27 2001-04-30 Degussa A.G. Hydantoin-racemase
US6713288B1 (en) * 1999-09-28 2004-03-30 University Of Stuttgart Whole cell catalysts
JP4561009B2 (ja) * 2001-07-10 2010-10-13 味の素株式会社 Ｄ−ヒダントインハイドロラーゼをコードするｄｎａ、ｎ−カルバミル−ｄ−アミノ酸ハイドロラーゼをコードするｄｎａ、該遺伝子を含む組み換えｄｎａ、該組み換えｄｎａにより形質転換された細胞、該形質転換細胞を用いるタンパク質の製造方法、および、ｄ−アミノ酸の製造方法

Also Published As

Publication number Publication date
US7582454B2 (en) 2009-09-01
US20020102713A1 (en) 2002-08-01
US20050084946A1 (en) 2005-04-21
EP1188826B1 (de) 2011-06-08
EP1188826A3 (de) 2002-05-15
US7112431B2 (en) 2006-09-26
US6815195B2 (en) 2004-11-09
SG109959A1 (en) 2005-04-28
EP1188826A2 (de) 2002-03-20
US20060246553A1 (en) 2006-11-02

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