DK0828004T3 - Proteindisulfidisomerase-gen afledt af stamme af methylotrof gær - Google Patents
Proteindisulfidisomerase-gen afledt af stamme af methylotrof gærInfo
- Publication number
- DK0828004T3 DK0828004T3 DK97306871T DK97306871T DK0828004T3 DK 0828004 T3 DK0828004 T3 DK 0828004T3 DK 97306871 T DK97306871 T DK 97306871T DK 97306871 T DK97306871 T DK 97306871T DK 0828004 T3 DK0828004 T3 DK 0828004T3
- Authority
- DK
- Denmark
- Prior art keywords
- strain
- disulfide isomerase
- protein disulfide
- methylotrophic yeast
- gene derived
- Prior art date
Links
- 108020003519 protein disulfide isomerase Proteins 0.000 title abstract 3
- 240000004808 Saccharomyces cerevisiae Species 0.000 title abstract 2
- 102000006010 Protein Disulfide-Isomerase Human genes 0.000 abstract 2
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 2
- 150000001413 amino acids Chemical class 0.000 abstract 2
- 102000004169 proteins and genes Human genes 0.000 abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 238000012217 deletion Methods 0.000 abstract 1
- 230000037430 deletion Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 238000006467 substitution reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
- C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
- C12N15/815—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts for yeasts other than Saccharomyces
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/90—Isomerases (5.)
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Mycology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP23428796 | 1996-09-04 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0828004T3 true DK0828004T3 (da) | 2007-03-19 |
Family
ID=16968627
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK97306871T DK0828004T3 (da) | 1996-09-04 | 1997-09-04 | Proteindisulfidisomerase-gen afledt af stamme af methylotrof gær |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US5965426A (da) |
| EP (1) | EP0828004B1 (da) |
| AT (1) | ATE346941T1 (da) |
| DE (1) | DE69737007T2 (da) |
| DK (1) | DK0828004T3 (da) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0121084D0 (en) * | 2001-08-31 | 2001-10-24 | Univ Leeds | Improved productivity of heterologous gene expression |
| US9057061B2 (en) | 2003-12-23 | 2015-06-16 | Novozymes Biopharma Dk A/S | Gene expression technique |
| ES2537806T5 (es) * | 2007-10-31 | 2018-10-09 | Daiichi Sankyo Company, Limited | Método para la secreción y producción de alto nivel de proteína |
| CN106085995B (zh) * | 2016-06-15 | 2019-07-12 | 华南理工大学 | 一种基因定点改造的蛋白质二硫键异构酶及其应用 |
| EP4402257A4 (en) * | 2021-09-17 | 2025-08-27 | Univ North Carolina Chapel Hill | MODIFIED PROTEIN DISULFIDE ISOMERASE AND ITS USES |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0638771A (ja) * | 1990-10-31 | 1994-02-15 | Tonen Corp | ヒトプロテインジスルフィドイソメラーゼ遺伝子の発現方法および該遺伝子との共発現によるポリペプチドの製造方法 |
| US5496719A (en) * | 1992-05-27 | 1996-03-05 | Kabushiki Kaisha Toyota Chuo Kenkyusho | Polypeptide from Humicola insolens possessing protein disulfide isomerase activity gene encoding the same |
| US6291205B1 (en) * | 1992-06-12 | 2001-09-18 | Merck & Co., Inc. | Method of increasing production of disulfide bonded recombinant proteins by saccharomyces cerevisiae |
-
1997
- 1997-09-04 AT AT97306871T patent/ATE346941T1/de not_active IP Right Cessation
- 1997-09-04 EP EP97306871A patent/EP0828004B1/en not_active Expired - Lifetime
- 1997-09-04 DK DK97306871T patent/DK0828004T3/da active
- 1997-09-04 US US08/923,536 patent/US5965426A/en not_active Expired - Lifetime
- 1997-09-04 DE DE69737007T patent/DE69737007T2/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP0828004A3 (en) | 1999-02-17 |
| DE69737007T2 (de) | 2007-06-06 |
| US5965426A (en) | 1999-10-12 |
| EP0828004B1 (en) | 2006-11-29 |
| DE69737007D1 (de) | 2007-01-11 |
| ATE346941T1 (de) | 2006-12-15 |
| EP0828004A2 (en) | 1998-03-11 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AU7550098A (en) | System for expressing hyperthermostable protein | |
| AU1551701A (en) | Novel carbonyl reductase, gene thereof and method of using the same | |
| DE69521752D1 (de) | Verfahren für die Herstellung von Proteinen | |
| AU2001271786A1 (en) | Interferon-like protein zcyto21 | |
| ATE125867T1 (de) | Fibronektinbindungsprotein und dessen herstellung. | |
| ATE284954T1 (de) | Hyaluronan synthase gen und seine verwendung | |
| CA2180103A1 (en) | Gene encoding adseverin | |
| AU2002307510A1 (en) | Cytokine protein family | |
| ATE120494T1 (de) | Fibronectinbindungsprotein und dessen herstellung. | |
| DE69839178D1 (de) | Gene, die für proteine mit transglykolysierungsaktivität kodieren. | |
| ATE334195T1 (de) | Proteine mit zellulase-aktivitäten und prozess für ihre herstellung | |
| DK0828004T3 (da) | Proteindisulfidisomerase-gen afledt af stamme af methylotrof gær | |
| DE59409964D1 (de) | Rekombinante D-Hydantoinase, Verfahren zur Herstellung und Verwendung | |
| ES2124694T3 (es) | Clonacion de la n-metil-hidantoinasa. | |
| EP1188826A3 (en) | 5-substituted hydantoin racemase, DNA coding for the same, and process for producing optically active amino acids | |
| DE69533626D1 (de) | Tioredioxine h aus zwig und hart-weizen und ähnliche proteine, diese kodierende dna-fragmente und verfahren zu ihrer herstellung | |
| DE59108261D1 (de) | Peptide des HIV-gag Proteins, ihre Herstellung und Verwendung | |
| EP1462516A4 (en) | MUTATED 6-PHOSPHOGLUCONATE DEHYDROGENASE | |
| ATE278784T1 (de) | Polypeptide | |
| EP0945512A3 (en) | Novel serine proteases | |
| DE69528575D1 (de) | Antifungale proteine, dafür kodierende dna, und diese enthaltende wirtzelle | |
| ATE432985T1 (de) | Polypeptide mit aktivität der stimulierung von neutrophilen | |
| WO2002026978A1 (en) | Novel proteins, genes encoding them and method of using the same | |
| ATE301199T1 (de) | Beta-primeverosidase gen | |
| ATE485380T1 (de) | Unter salzstress erhöhte expression aufweisende nukleinsäuren und proteine |