ATE512218T1 - Zusammensetzung zur herstellung, regeneration und reparatur von geweben unter verwendung eines zellentragenden biologischen implantats, das mit einem blutplättchenkonzentrat und supplementen angereichert ist - Google Patents

Zusammensetzung zur herstellung, regeneration und reparatur von geweben unter verwendung eines zellentragenden biologischen implantats, das mit einem blutplättchenkonzentrat und supplementen angereichert ist

Info

Publication number: ATE512218T1
Authority: AT; Austria
Prior art keywords: supplements; composition; platelet concentrate; enriched; regeneration
Prior art date: 2002-01-09

Application number

AT02716089T

Other languages

English (en)

Inventor

Barrueta Alberto Gorrochategui

Elizundia Josu Simon

Original Assignee

Barrueta Alberto Gorrochategui

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-01-09

Filing date

2002-01-09

Publication date

2011-06-15

2002-01-09 Application filed by Barrueta Alberto Gorrochategui filed Critical Barrueta Alberto Gorrochategui

2011-06-15 Application granted granted Critical

2011-06-15 Publication of ATE512218T1 publication Critical patent/ATE512218T1/de

Links

239000013589 supplement Substances 0.000 title abstract 3
239000000203 mixture Substances 0.000 title abstract 2
239000003634 thrombocyte concentrate Substances 0.000 title abstract 2
239000007943 implant Substances 0.000 title 1
238000004519 manufacturing process Methods 0.000 title 1
230000008929 regeneration Effects 0.000 title 1
238000011069 regeneration method Methods 0.000 title 1
210000004027 cell Anatomy 0.000 abstract 2
ZKHQWZAMYRWXGA-KQYNXXCUSA-J ATP(4-) Chemical compound C1=NC=2C(N)=NC=NC=2N1[C@@H]1O[C@H](COP([O-])(=O)OP([O-])(=O)OP([O-])([O-])=O)[C@@H](O)[C@H]1O ZKHQWZAMYRWXGA-KQYNXXCUSA-J 0.000 abstract 1
ZKHQWZAMYRWXGA-UHFFFAOYSA-N Adenosine triphosphate Natural products C1=NC=2C(N)=NC=NC=2N1C1OC(COP(O)(=O)OP(O)(=O)OP(O)(O)=O)C(O)C1O ZKHQWZAMYRWXGA-UHFFFAOYSA-N 0.000 abstract 1
102000008946 Fibrinogen Human genes 0.000 abstract 1
108010049003 Fibrinogen Proteins 0.000 abstract 1
210000001789 adipocyte Anatomy 0.000 abstract 1
150000001413 amino acids Chemical class 0.000 abstract 1
210000001612 chondrocyte Anatomy 0.000 abstract 1
229940012952 fibrinogen Drugs 0.000 abstract 1
210000002950 fibroblast Anatomy 0.000 abstract 1
239000003102 growth factor Substances 0.000 abstract 1
210000003494 hepatocyte Anatomy 0.000 abstract 1
239000005556 hormone Substances 0.000 abstract 1
229940088597 hormone Drugs 0.000 abstract 1
229910052500 inorganic mineral Inorganic materials 0.000 abstract 1
150000002632 lipids Chemical class 0.000 abstract 1
239000011707 mineral Substances 0.000 abstract 1
239000002777 nucleoside Substances 0.000 abstract 1
125000003835 nucleoside group Chemical group 0.000 abstract 1
210000000963 osteoblast Anatomy 0.000 abstract 1
230000035755 proliferation Effects 0.000 abstract 1
210000003583 retinal pigment epithelium Anatomy 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
210000000130 stem cell Anatomy 0.000 abstract 1
230000001173 tumoral effect Effects 0.000 abstract 1
239000011782 vitamin Substances 0.000 abstract 1
229940088594 vitamin Drugs 0.000 abstract 1
229930003231 vitamin Natural products 0.000 abstract 1
235000013343 vitamin Nutrition 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
- A61L27/3616—Blood, e.g. platelet-rich plasma
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
- A61K35/19—Platelets; Megacaryocytes
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1858—Platelet-derived growth factor [PDGF]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/36—Blood coagulation or fibrinolysis factors
- A61K38/363—Fibrinogen
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
- A61L24/0005—Ingredients of undetermined constitution or reaction products thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
- A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
- A61L24/10—Polypeptides; Proteins
- A61L24/106—Fibrin; Fibrinogen
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
- A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
- A61L26/0028—Polypeptides; Proteins; Degradation products thereof
- A61L26/0042—Fibrin; Fibrinogen
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
- A61L26/0057—Ingredients of undetermined constitution or reaction products thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3839—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by the site of application in the body
- A61L27/3843—Connective tissue
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0018—Culture media for cell or tissue culture
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/05—Inorganic components
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
- C12N2500/36—Lipids
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
- C12N2500/38—Vitamins
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
- C12N2500/42—Organic phosphate, e.g. beta glycerophosphate
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/70—Undefined extracts
- C12N2500/80—Undefined extracts from animals
- C12N2500/84—Undefined extracts from animals from mammals
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/01—Modulators of cAMP or cGMP, e.g. non-hydrolysable analogs, phosphodiesterase inhibitors, cholera toxin
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/30—Hormones
- C12N2501/33—Insulin
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/30—Hormones
- C12N2501/335—Glucagon; Glucagon-like peptide [GLP]; Exendin
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/30—Hormones
- C12N2501/38—Hormones with nuclear receptors
- C12N2501/39—Steroid hormones
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/30—Hormones
- C12N2501/38—Hormones with nuclear receptors
- C12N2501/395—Thyroid hormones
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Epidemiology (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Biomedical Technology (AREA)
Zoology (AREA)
Medicinal Chemistry (AREA)
Biotechnology (AREA)
Bioinformatics & Cheminformatics (AREA)
Hematology (AREA)
Pharmacology & Pharmacy (AREA)
Immunology (AREA)
Chemical Kinetics & Catalysis (AREA)
Cell Biology (AREA)
Oral & Maxillofacial Surgery (AREA)
Genetics & Genomics (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Developmental Biology & Embryology (AREA)
Materials Engineering (AREA)
Surgery (AREA)
Organic Chemistry (AREA)
Botany (AREA)
Dermatology (AREA)
Virology (AREA)
Transplantation (AREA)
Gastroenterology & Hepatology (AREA)
Wood Science & Technology (AREA)
Molecular Biology (AREA)
Microbiology (AREA)
Urology & Nephrology (AREA)
Biochemistry (AREA)
General Engineering & Computer Science (AREA)
Vascular Medicine (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)

AT02716089T 2002-01-09 2002-01-09 Zusammensetzung zur herstellung, regeneration und reparatur von geweben unter verwendung eines zellentragenden biologischen implantats, das mit einem blutplättchenkonzentrat und supplementen angereichert ist ATE512218T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
PCT/ES2002/000007 WO2003057865A1 (es)	2002-01-09	2002-01-09	Composicion y procedimiento para crear, regenerar y reparar tejidos mediante implante biologico portador de celulas y enriquecido con concentrado de plaquetas mas suplementos.

Publications (1)

Publication Number	Publication Date
ATE512218T1 true ATE512218T1 (de)	2011-06-15

Family

ID=8244417

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT02716089T ATE512218T1 (de)	2002-01-09	2002-01-09	Zusammensetzung zur herstellung, regeneration und reparatur von geweben unter verwendung eines zellentragenden biologischen implantats, das mit einem blutplättchenkonzentrat und supplementen angereichert ist

Country Status (6)

Country	Link
US (1)	US20040151709A1 (de)
EP (1)	EP1464697B1 (de)
AT (1)	ATE512218T1 (de)
AU (1)	AU2002226426A1 (de)
ES (1)	ES2370012T3 (de)
WO (1)	WO2003057865A1 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20060039990A1 (en) *	2004-08-20	2006-02-23	Barrueta Alberto G	Biological tissue regenerative agent and method for preparing same
WO2006054448A1 (ja) *	2004-11-19	2006-05-26	Jms Co., Ltd.	細胞培養用ヒト血清
EP1764117A1 (de)	2005-09-20	2007-03-21	Zimmer GmbH	Implantat zur Wiederherstellung von Knorpeldefekten und Verfahren zu seiner Herstellung
ITTO20060282A1 (it) *	2006-04-14	2007-10-15	Univ Degli Studi Torino	Mezzo di coltura e composizione farmaceutica per la rigenerazione del tessuto cartilagineo relativo procedimento relativi usi e prodotti
WO2008022651A1 (en)	2006-08-21	2008-02-28	Antoine Turzi	Process and device for the preparation of platelet rich plasma for extemporaneous use and combination thereof with skin and bone cells
ES2982461T3 (es) *	2008-09-16	2024-10-16	Mayo Found Medical Education & Res	Composiciones que contienen contenido plaquetario
GB201004072D0 (en) *	2010-03-11	2010-04-28	Turzi Antoine	Process, tube and device for the preparation of wound healant composition
WO2011139132A2 (ko) *	2010-05-07	2011-11-10	한국생명공학연구원	줄기세포로부터 생성된 배아체를 대량 증식 및 유지하는 방법
US20140170748A1 (en) *	2012-12-14	2014-06-19	DePuy Synthes Products, LLC	Nutrient Enriched Media for hUTC Growth
US11891620B2 (en)	2014-05-16	2024-02-06	Mayo Foundation For Medical Education And Research	Cell culture media compositions for primary cells
RU2748057C2 (ru)	2016-01-14	2021-05-19	Депуи Синтез Продактс, Инк.	Композиция и способы криоконсервации клеток hutc
WO2020154305A1 (en)	2019-01-21	2020-07-30	Eclipse Medcorp, Llc	Methods, systems and apparatus for separating components of a biological sample
US12007382B2 (en)	2019-10-31	2024-06-11	Crown Laboratories, Inc.	Systems, methods and apparatus for separating components of a sample
CN117017897A (zh) *	2022-03-18	2023-11-10	沈阳药科大学	一种埋植剂及其释药量的测试方法
CN117138051A (zh) *	2022-03-18	2023-12-01	沈阳药科大学	一种硅胶材料及其制备方法、硅胶管、含其的埋植剂
CN116808226A (zh) *	2022-03-18	2023-09-29	沈阳药科大学	一种药物组合物及其制备方法和应用、含其的埋植剂
CN119656097A (zh) *	2023-09-13	2025-03-21	沈阳药科大学	药物组合物、棒芯和埋植剂及其制备方法、应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4957742A (en) *	1984-11-29	1990-09-18	Regents Of The University Of Minnesota	Method for promoting hair growth
US5197985A (en) *	1990-11-16	1993-03-30	Caplan Arnold I	Method for enhancing the implantation and differentiation of marrow-derived mesenchymal cells
EP0564502B1 (de) *	1990-11-27	2002-01-30	The American National Red Cross	Gewebeabdeckung und wachstumsfaktor enthaltende verbindungen zur förderung beschleunigter wundheilung
FR2691911B1 (fr) *	1992-06-05	1994-11-25	Delmas Olivier	Dispositif permettant l'obtention d'un surnageant de thrombocytes activés, procédé mettant en Óoeuvre le dispositif et surnageant obtenu.
US5972703A (en) *	1994-08-12	1999-10-26	The Regents Of The University Of Michigan	Bone precursor cells: compositions and methods
US5908782A (en) *	1995-06-05	1999-06-01	Osiris Therapeutics, Inc.	Chemically defined medium for human mesenchymal stem cells
US6723131B2 (en) *	2001-02-28	2004-04-20	The Cleveland Clinic Foundation	Composite bone marrow graft material with method and kit

2002
- 2002-01-09 AU AU2002226426A patent/AU2002226426A1/en not_active Abandoned
- 2002-01-09 US US10/475,866 patent/US20040151709A1/en not_active Abandoned
- 2002-01-09 ES ES02716089T patent/ES2370012T3/es not_active Expired - Lifetime
- 2002-01-09 AT AT02716089T patent/ATE512218T1/de not_active IP Right Cessation
- 2002-01-09 EP EP02716089A patent/EP1464697B1/de not_active Expired - Lifetime
- 2002-01-09 WO PCT/ES2002/000007 patent/WO2003057865A1/es not_active Ceased

Also Published As

Publication number	Publication date
WO2003057865A1 (es)	2003-07-17
EP1464697A1 (de)	2004-10-06
ES2370012T3 (es)	2011-12-12
EP1464697B1 (de)	2011-06-08
WO2003057865A8 (es)	2003-10-23
US20040151709A1 (en)	2004-08-05
AU2002226426A1 (en)	2003-07-24

Legal Events

Date	Code	Title	Description
2011-12-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
AU2002226426A1 (en)	2003-07-24	Composition and method of creating, regenerating and repairing tissues using a cell-carrying biological implant which is enriched with a platelet concentrate and supplements
O'driscoll et al.	1984	The induction of neochondrogenesis in free intra-articular periosteal autografts under the influence of continuous passive motion. An experimental investigation in the rabbit.
Waymouth	2012	Construction of tissue culture media
Ishikawa et al.	2009	Cell sheet engineering and other novel cell-based approaches to periodontal regeneration.
ES2119250T3 (es)	1998-10-01	Composiciones y metodos para estimular el crecimiento y diferenciacion de megacariocitos.
US10184112B2 (en)	2019-01-22	Culture medium additive for use in serum-free culturing of animal cell, kit and use thereof
ATE449183T1 (de)	2009-12-15	Verfahren zur herstellung von dipeptiden oder dipeptidderivaten.
CA2285382A1 (en)	1998-10-15	Neocartilage and methods of use
ATE543509T1 (de)	2012-02-15	Material und verfahren zur förderung der reparatur von nervengewebe
BR0315645A (pt)	2005-08-30	Polipetìdeos de fusão de actrib e seus usos
DK1201749T3 (da)	2008-01-07	Fremgangsmåde til fremstilling af humane bruskimplantater ved hjælp af in vitro dyrkede chondrocytter
BR0210599A (pt)	2004-07-20	Uso de monóxido de carbono, método para manutenção de uma célula animal in vitro, artigo de manufatura, bem como meio celular estéril
SE416175B (sv)	1980-12-08	For implantering i kroppsvevnad serskilt benvevnad, avsett material
DE69533223D1 (de)	2004-08-05	Zusammensetzungen und verfahren zur stimulierung der proliferation und der differenzierung von menschlichen fetalen und erwachsenen pankreatischen zellen ex vivo
Takagishi et al.	2006	Bone-like tissue formation by three-dimensional culture of MG63 osteosarcoma cells in gelatin hydrogels using calcium-enriched medium
BR0316757A (pt)	2005-10-25	Composições de meio de cultura de célula, processo para a cultura de célula progenitoras e/ou tronco, processo para a produção de mioblastos, população de células, e uso de mioblastos
ATE541594T1 (de)	2012-02-15	Methoden und zusammensetzungen zur heilung und reparatur von gelenkknorpeln
CN105886464A (zh)	2016-08-24	一种脐带血间充质干细胞的无血清培养基
CN105838675A (zh)	2016-08-10	一种造血干细胞无血清培养基
ES2198216B1 (es)	2005-04-16	Medio de cultivo de celulas madre-progenitoras autologas humanas y sus aplicaciones.
BR0214860A (pt)	2004-12-14	Construto ou tecido celular, processo de preparação de um construto celular, utilização de um construto, método de preparação de um implante com ajuda de um construto, kit para a preparação de um construto, composição farmacêutica e implante
KR101831469B1 (ko)	2018-02-22	인간 간엽 줄기세포용 배지
CN107475185A (zh)	2017-12-15	一种用于培养人间充质干细胞的无动物源成分培养基
Bulgin et al.	2011	Advanced and prospective technologies for potential use in craniofacial tissues regeneration by stem cells and growth factors
Khan et al.	2012	Oral tissues as source for bone regeneration in dental implantology