ATE512964T1 - N8,n13-disubstituierte chinoä4,3,2,klüacridinium salze als arzneimittel - Google Patents
N8,n13-disubstituierte chinoä4,3,2,klüacridinium salze als arzneimittelInfo
- Publication number
- ATE512964T1 ATE512964T1 AT01976448T AT01976448T ATE512964T1 AT E512964 T1 ATE512964 T1 AT E512964T1 AT 01976448 T AT01976448 T AT 01976448T AT 01976448 T AT01976448 T AT 01976448T AT E512964 T1 ATE512964 T1 AT E512964T1
- Authority
- AT
- Austria
- Prior art keywords
- sup
- disubstituted
- salts
- klüacridinium
- chinoä4
- Prior art date
Links
- 229940126601 medicinal product Drugs 0.000 title 1
- 125000001424 substituent group Chemical group 0.000 abstract 3
- 108010017842 Telomerase Proteins 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen group Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 abstract 2
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- DZBUGLKDJFMEHC-UHFFFAOYSA-O acridine;hydron Chemical class C1=CC=CC2=CC3=CC=CC=C3[NH+]=C21 DZBUGLKDJFMEHC-UHFFFAOYSA-O 0.000 abstract 1
- 150000001450 anions Chemical group 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 230000004663 cell proliferation Effects 0.000 abstract 1
- 238000000338 in vitro Methods 0.000 abstract 1
- 238000001727 in vivo Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000002062 proliferating effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/06—Peri-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US23926700P | 2000-10-12 | 2000-10-12 | |
| PCT/GB2001/004557 WO2002030932A2 (en) | 2000-10-12 | 2001-10-12 | N8,n13-disubstituted quino[4,3,2-kl]acridinium salts as therapeutic agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE512964T1 true ATE512964T1 (de) | 2011-07-15 |
Family
ID=22901392
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT01976448T ATE512964T1 (de) | 2000-10-12 | 2001-10-12 | N8,n13-disubstituierte chinoä4,3,2,klüacridinium salze als arzneimittel |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US7115619B2 (de) |
| EP (1) | EP1330456B8 (de) |
| AT (1) | ATE512964T1 (de) |
| AU (1) | AU2001295718A1 (de) |
| DK (1) | DK1330456T3 (de) |
| ES (1) | ES2367968T3 (de) |
| WO (1) | WO2002030932A2 (de) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20080279961A1 (en) * | 2007-05-11 | 2008-11-13 | Burger Angelika M | Telomere targeting agents as stem cells directed treatments |
| KR101560844B1 (ko) * | 2007-06-04 | 2015-10-15 | 벤-구리온 유니버시티 오브 더 네게브 리서치 앤드 디벨럽먼트 어쏘러티 | 트라이-아릴계 화합물 및 이를 포함하는 조성물 |
| GB201016442D0 (en) | 2010-09-30 | 2010-11-17 | Pharminox Ltd | Novel acridine derivatives |
| WO2012175991A1 (en) | 2011-06-24 | 2012-12-27 | Pharminox Limited | Fused pentacyclic anti - proliferative compounds |
| CN112472699A (zh) | 2013-07-26 | 2021-03-12 | 种族肿瘤学公司 | 改善比生群及衍生物的治疗益处的组合方法 |
| MX2016005995A (es) | 2013-11-05 | 2016-08-17 | Ben-Gurion Univ Of The Negev Res And Dev Authority | Compuestos para el tratamiento de diabetes y complicaciones de la enfermedad derivadas de la misma. |
-
2001
- 2001-10-12 AU AU2001295718A patent/AU2001295718A1/en not_active Abandoned
- 2001-10-12 US US10/398,767 patent/US7115619B2/en not_active Expired - Fee Related
- 2001-10-12 DK DK01976448.9T patent/DK1330456T3/da active
- 2001-10-12 AT AT01976448T patent/ATE512964T1/de active
- 2001-10-12 WO PCT/GB2001/004557 patent/WO2002030932A2/en not_active Ceased
- 2001-10-12 EP EP01976448A patent/EP1330456B8/de not_active Expired - Lifetime
- 2001-10-12 ES ES01976448T patent/ES2367968T3/es not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| WO2002030932A2 (en) | 2002-04-18 |
| ES2367968T3 (es) | 2011-11-11 |
| EP1330456A2 (de) | 2003-07-30 |
| EP1330456B8 (de) | 2012-02-08 |
| DK1330456T3 (da) | 2011-10-03 |
| WO2002030932A3 (en) | 2002-08-22 |
| EP1330456B1 (de) | 2011-06-15 |
| US7115619B2 (en) | 2006-10-03 |
| AU2001295718A1 (en) | 2002-04-22 |
| US20040063739A1 (en) | 2004-04-01 |
| EP1330456B9 (de) | 2012-01-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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