ATE515573T1 - Verfahren zum nachweis der grösse von nukleinsäuren - Google Patents

Verfahren zum nachweis der grösse von nukleinsäuren

Info

Publication number
ATE515573T1
ATE515573T1 AT07755301T AT07755301T ATE515573T1 AT E515573 T1 ATE515573 T1 AT E515573T1 AT 07755301 T AT07755301 T AT 07755301T AT 07755301 T AT07755301 T AT 07755301T AT E515573 T1 ATE515573 T1 AT E515573T1
Authority
AT
Austria
Prior art keywords
size
nucleic acids
detecting
fragmentation
individuals
Prior art date
Application number
AT07755301T
Other languages
English (en)
Inventor
Donghui Huang
Charles Strom
Steven Potts
Jenny Rooke
Original Assignee
Quest Diagnostics Invest Inc
U S Genomics
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Quest Diagnostics Invest Inc, U S Genomics filed Critical Quest Diagnostics Invest Inc
Application granted granted Critical
Publication of ATE515573T1 publication Critical patent/ATE515573T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6858—Allele-specific amplification
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/17—Nitrogen containing

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Optical Measuring Cells (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
AT07755301T 2006-10-05 2007-04-11 Verfahren zum nachweis der grösse von nukleinsäuren ATE515573T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11/544,293 US8163480B2 (en) 2006-10-05 2006-10-05 Nucleic acid size detection method
PCT/US2007/008985 WO2008045136A2 (en) 2006-10-05 2007-04-11 Nucleic acid size detection method

Publications (1)

Publication Number Publication Date
ATE515573T1 true ATE515573T1 (de) 2011-07-15

Family

ID=39283328

Family Applications (1)

Application Number Title Priority Date Filing Date
AT07755301T ATE515573T1 (de) 2006-10-05 2007-04-11 Verfahren zum nachweis der grösse von nukleinsäuren

Country Status (10)

Country Link
US (2) US8163480B2 (de)
EP (1) EP2082055B1 (de)
JP (1) JP5386357B2 (de)
CN (1) CN101595227A (de)
AT (1) ATE515573T1 (de)
AU (1) AU2007307320B2 (de)
BR (1) BRPI0720549A2 (de)
CA (1) CA2665723A1 (de)
MX (1) MX2009003736A (de)
WO (1) WO2008045136A2 (de)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8163480B2 (en) * 2006-10-05 2012-04-24 Quest Diagnostics Investments Incorporated Nucleic acid size detection method
EP2140027B1 (de) * 2006-12-07 2012-07-18 Novartis AG Nichtinvasiver pränataler genetischer screen-test
US8409805B2 (en) * 2009-02-13 2013-04-02 Asuragen, Inc. Method of amplification of GC-rich DNA templates
AU2010215061B2 (en) * 2009-02-17 2016-07-14 E.D.G. Innovations and Consulting Pty Ltd Assay for determining epigenetic profiles of markers of Fragile X alleles
KR20110138387A (ko) 2009-03-24 2011-12-27 아수라겐, 인크. Ｆｍｒ１ 및 ｆｍｒ２ 유전자의 ５´ 비번역 영역을 규명하기 위한 ｐｃｒ 방법
CN101871001B (zh) * 2009-04-22 2013-09-25 中山大学达安基因股份有限公司 检测脆性x综合征的试剂盒
US8592158B2 (en) * 2009-07-10 2013-11-26 Perkinelmer Health Sciences, Inc. Detecting multinucleotide repeats
EP3460074B1 (de) 2010-02-05 2020-10-07 Quest Diagnostics Investments Incorporated Verfahren zur detektion von wiederholungssequenzmotiven in nukleinsäure
EP2603609B1 (de) 2010-08-11 2017-04-12 Murdoch Childrens Research Institute Diagnose epigenetischer störungen und erkrankungen
US20130316339A1 (en) * 2010-09-01 2013-11-28 Orion Genomics Llc Detection of nucleic acid sequences adjacent to repeated sequences
WO2012138289A1 (en) * 2011-04-08 2012-10-11 Zain-Luqman Rula Diagnosis and treatment of friedreich's ataxia
EP3848474A1 (de) 2011-11-04 2021-07-14 Gen-Probe Incorporated Molekulartestreagenzien und -verfahren
EP2888688B1 (de) 2012-07-20 2019-09-04 Asuragen, INC. Umfassende fmr1-genotypisierung
EP2732815A1 (de) * 2012-11-16 2014-05-21 Neurochlore Modulatoren der intrazellulären Chloridkonzentration zur Behandlung des Fragilen X-Syndroms
GB201301164D0 (en) * 2013-01-23 2013-03-06 Medical Res Council Methods for estimating the size of disease-associated polynucleotide repaet expansions in genes
WO2014152822A2 (en) 2013-03-14 2014-09-25 Quest Diagnostics Investments Incorporated Method for detecting cystic fibrosis
US9273349B2 (en) * 2013-03-14 2016-03-01 Affymetrix, Inc. Detection of nucleic acids
GB201418144D0 (en) * 2014-10-14 2014-11-26 Univ Cardiff High throughput sequencing
CN104816447B (zh) * 2015-04-30 2017-03-08 青岛科技大学 一种行星齿轮式混炼装置
CN104862302B (zh) * 2015-05-05 2020-12-15 华南师范大学 一种dna片段化的方法及实现该方法的装置
GB201511508D0 (en) 2015-07-01 2015-08-12 Ge Healthcare Bio Sciences Ab Method for determining a size of biomolecules
JP2019013206A (ja) * 2017-07-11 2019-01-31 国立大学法人帯広畜産大学 アゾール耐性アスペルギルス・フミガーツスの検出方法および検出キット
CN110184344A (zh) * 2019-06-28 2019-08-30 北京和合医学诊断技术股份有限公司 检测htt基因cag三核苷酸重复序列的方法及引物对
CN110923305B (zh) * 2019-11-25 2023-12-29 广州市达瑞生物技术股份有限公司 一种适用于脆性X综合征southern blot印迹杂交检测的DNA分子量标准
US11319613B2 (en) 2020-08-18 2022-05-03 Enviro Metals, LLC Metal refinement
CN115851915A (zh) * 2022-12-13 2023-03-28 长沙金域医学检验实验室有限公司 检测遗传性共济失调致病基因的引物组及方法

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Publication number Priority date Publication date Assignee Title
GB8606719D0 (en) 1986-03-19 1986-04-23 Lister Preventive Med Genetic probes
US5135717A (en) 1986-12-24 1992-08-04 British Technology Group Usa Inc. Tetrabenztriazaporphyrin reagents and kits containing the same
US5206137A (en) 1988-09-08 1993-04-27 Lifecodes Corporation Compositions and methods useful for genetic analysis
US5714327A (en) 1990-07-19 1998-02-03 Kreatech Diagnostics Platinum-containing compounds, methods for their preparation and applications thereof
NL9001639A (nl) 1990-07-19 1992-02-17 Amc Amsterdam Pt-houdende verbinding, werkwijze voor de bereiding ervan, alsmede toepassing van dergelijke verbindingen.
US5364759B2 (en) 1991-01-31 1999-07-20 Baylor College Medicine Dna typing with short tandem repeat polymorphisms and identification of polymorphic short tandem repeats
US5652099A (en) 1992-02-12 1997-07-29 Conrad; Michael J. Probes comprising fluorescent nucleosides and uses thereof
US5695933A (en) * 1993-05-28 1997-12-09 Massachusetts Institute Of Technology Direct detection of expanded nucleotide repeats in the human genome
US5599666A (en) 1994-03-28 1997-02-04 Promega Corporation Allelic ladders for short tandem repeat loci
US6013444A (en) 1997-09-18 2000-01-11 Oligotrail, Llc DNA bracketing locus compatible standards for electrophoresis
US6238863B1 (en) 1998-02-04 2001-05-29 Promega Corporation Materials and methods for indentifying and analyzing intermediate tandem repeat DNA markers
US6074831A (en) 1998-07-09 2000-06-13 Agilent Technologies, Inc. Partitioning of polymorphic DNAs
WO2002081729A2 (en) 2001-04-06 2002-10-17 California Institute Of Technology Nucleic acid amplification utilizing microfluidic devices
US7855053B2 (en) 2006-07-19 2010-12-21 The Regents Of The University Of California Methods for detecting the presence of expanded CGG repeats in the FMR1 gene 5′ untranslated region
US8163480B2 (en) * 2006-10-05 2012-04-24 Quest Diagnostics Investments Incorporated Nucleic acid size detection method

Also Published As

Publication number Publication date
EP2082055A4 (de) 2010-02-17
JP5386357B2 (ja) 2014-01-15
JP2010505413A (ja) 2010-02-25
BRPI0720549A2 (pt) 2014-07-29
WO2008045136A2 (en) 2008-04-17
US20100167284A1 (en) 2010-07-01
EP2082055A2 (de) 2009-07-29
US8163480B2 (en) 2012-04-24
CN101595227A (zh) 2009-12-02
MX2009003736A (es) 2009-07-09
WO2008045136A3 (en) 2008-12-11
EP2082055B1 (de) 2011-07-06
AU2007307320A1 (en) 2008-04-17
AU2007307320B2 (en) 2013-07-11
CA2665723A1 (en) 2008-04-17
US20080124709A1 (en) 2008-05-29
US8697399B2 (en) 2014-04-15

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