ATE515573T1 - Verfahren zum nachweis der grösse von nukleinsäuren - Google Patents

Verfahren zum nachweis der grösse von nukleinsäuren

Info

Publication number
ATE515573T1
ATE515573T1 AT07755301T AT07755301T ATE515573T1 AT E515573 T1 ATE515573 T1 AT E515573T1 AT 07755301 T AT07755301 T AT 07755301T AT 07755301 T AT07755301 T AT 07755301T AT E515573 T1 ATE515573 T1 AT E515573T1
Authority
AT
Austria
Prior art keywords
size
nucleic acids
detecting
fragmentation
individuals
Prior art date
Application number
AT07755301T
Other languages
English (en)
Inventor
Donghui Huang
Charles Strom
Steven Potts
Jenny Rooke
Original Assignee
Quest Diagnostics Invest Inc
U S Genomics
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Quest Diagnostics Invest Inc, U S Genomics filed Critical Quest Diagnostics Invest Inc
Application granted granted Critical
Publication of ATE515573T1 publication Critical patent/ATE515573T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6858—Allele-specific amplification
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/17—Nitrogen containing

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
  • Optical Measuring Cells (AREA)
AT07755301T 2006-10-05 2007-04-11 Verfahren zum nachweis der grösse von nukleinsäuren ATE515573T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11/544,293 US8163480B2 (en) 2006-10-05 2006-10-05 Nucleic acid size detection method
PCT/US2007/008985 WO2008045136A2 (en) 2006-10-05 2007-04-11 Nucleic acid size detection method

Publications (1)

Publication Number Publication Date
ATE515573T1 true ATE515573T1 (de) 2011-07-15

Family

ID=39283328

Family Applications (1)

Application Number Title Priority Date Filing Date
AT07755301T ATE515573T1 (de) 2006-10-05 2007-04-11 Verfahren zum nachweis der grösse von nukleinsäuren

Country Status (10)

Country Link
US (2) US8163480B2 (de)
EP (1) EP2082055B1 (de)
JP (1) JP5386357B2 (de)
CN (1) CN101595227A (de)
AT (1) ATE515573T1 (de)
AU (1) AU2007307320B2 (de)
BR (1) BRPI0720549A2 (de)
CA (1) CA2665723A1 (de)
MX (1) MX2009003736A (de)
WO (1) WO2008045136A2 (de)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8163480B2 (en) * 2006-10-05 2012-04-24 Quest Diagnostics Investments Incorporated Nucleic acid size detection method
WO2008070862A2 (en) * 2006-12-07 2008-06-12 Biocept, Inc. Non-invasive prenatal genetic screen
US8409805B2 (en) * 2009-02-13 2013-04-02 Asuragen, Inc. Method of amplification of GC-rich DNA templates
US20120094288A1 (en) * 2009-02-17 2012-04-19 Murdoch Childrens Research Institute Assay for determining epigenetic profiles of markers of fragile x alleles
US8679757B2 (en) 2009-03-24 2014-03-25 Asuragen, Inc. PCR methods for characterizing the 5′ untranslated region of the FMR1 and FMR2 genes
CN101871001B (zh) * 2009-04-22 2013-09-25 中山大学达安基因股份有限公司 检测脆性x综合征的试剂盒
CA2767521A1 (en) * 2009-07-10 2011-01-13 Perkinelmer Health Sciences, Inc. Detecting multinucleotide repeats
EP3460074B1 (de) 2010-02-05 2020-10-07 Quest Diagnostics Investments Incorporated Verfahren zur detektion von wiederholungssequenzmotiven in nukleinsäure
US20130210007A1 (en) 2010-08-11 2013-08-15 Murdoch Childrens Research Institute Treatment and diagnosis of epigenetic disorders and conditions
US20130316339A1 (en) * 2010-09-01 2013-11-28 Orion Genomics Llc Detection of nucleic acid sequences adjacent to repeated sequences
US9476043B2 (en) * 2011-04-08 2016-10-25 Rula Zain-Luqman Diagnosis and treatment of friedreich's ataxia
US9863004B2 (en) 2011-11-04 2018-01-09 Gen-Probe Incorporated Molecular assay reagents and methods
ES2759023T3 (es) 2012-07-20 2020-05-07 Asuragen Inc Genotipificación completa de FMR1
EP2732815A1 (de) * 2012-11-16 2014-05-21 Neurochlore Modulatoren der intrazellulären Chloridkonzentration zur Behandlung des Fragilen X-Syndroms
GB201301164D0 (en) * 2013-01-23 2013-03-06 Medical Res Council Methods for estimating the size of disease-associated polynucleotide repaet expansions in genes
CN105247073A (zh) 2013-03-14 2016-01-13 奎斯特诊断投资股份有限公司 用于检测囊性纤维化病的方法
US9273349B2 (en) * 2013-03-14 2016-03-01 Affymetrix, Inc. Detection of nucleic acids
GB201418144D0 (en) * 2014-10-14 2014-11-26 Univ Cardiff High throughput sequencing
CN104816447B (zh) * 2015-04-30 2017-03-08 青岛科技大学 一种行星齿轮式混炼装置
CN104862302B (zh) * 2015-05-05 2020-12-15 华南师范大学 一种dna片段化的方法及实现该方法的装置
GB201511508D0 (en) 2015-07-01 2015-08-12 Ge Healthcare Bio Sciences Ab Method for determining a size of biomolecules
JP2019013206A (ja) * 2017-07-11 2019-01-31 国立大学法人帯広畜産大学 アゾール耐性アスペルギルス・フミガーツスの検出方法および検出キット
CN110184344A (zh) * 2019-06-28 2019-08-30 北京和合医学诊断技术股份有限公司 检测htt基因cag三核苷酸重复序列的方法及引物对
CN110923305B (zh) * 2019-11-25 2023-12-29 广州市达瑞生物技术股份有限公司 一种适用于脆性X综合征southern blot印迹杂交检测的DNA分子量标准
AU2021329906A1 (en) 2020-08-18 2023-04-27 Enviro Metals, LLC Metal refinement
EP4587584A4 (de) * 2022-09-14 2026-04-08 Revvity Health Sciences Inc Verfahren und zusammensetzungen für einzelsträngige nukleinsäureleiter durch geführte spaltung
CN115851915A (zh) * 2022-12-13 2023-03-28 长沙金域医学检验实验室有限公司 检测遗传性共济失调致病基因的引物组及方法

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GB8606719D0 (en) * 1986-03-19 1986-04-23 Lister Preventive Med Genetic probes
US5135717A (en) * 1986-12-24 1992-08-04 British Technology Group Usa Inc. Tetrabenztriazaporphyrin reagents and kits containing the same
US5206137A (en) * 1988-09-08 1993-04-27 Lifecodes Corporation Compositions and methods useful for genetic analysis
NL9001639A (nl) * 1990-07-19 1992-02-17 Amc Amsterdam Pt-houdende verbinding, werkwijze voor de bereiding ervan, alsmede toepassing van dergelijke verbindingen.
US5714327A (en) * 1990-07-19 1998-02-03 Kreatech Diagnostics Platinum-containing compounds, methods for their preparation and applications thereof
US5364759B2 (en) * 1991-01-31 1999-07-20 Baylor College Medicine Dna typing with short tandem repeat polymorphisms and identification of polymorphic short tandem repeats
US5652099A (en) * 1992-02-12 1997-07-29 Conrad; Michael J. Probes comprising fluorescent nucleosides and uses thereof
US5695933A (en) * 1993-05-28 1997-12-09 Massachusetts Institute Of Technology Direct detection of expanded nucleotide repeats in the human genome
US5599666A (en) * 1994-03-28 1997-02-04 Promega Corporation Allelic ladders for short tandem repeat loci
US6013444A (en) * 1997-09-18 2000-01-11 Oligotrail, Llc DNA bracketing locus compatible standards for electrophoresis
US6238863B1 (en) * 1998-02-04 2001-05-29 Promega Corporation Materials and methods for indentifying and analyzing intermediate tandem repeat DNA markers
US6074831A (en) * 1998-07-09 2000-06-13 Agilent Technologies, Inc. Partitioning of polymorphic DNAs
EP1384022A4 (de) * 2001-04-06 2004-08-04 California Inst Of Techn Nukleinsäure-amplifikation verwendende mikrofluidvorrichtungen
US7855053B2 (en) 2006-07-19 2010-12-21 The Regents Of The University Of California Methods for detecting the presence of expanded CGG repeats in the FMR1 gene 5′ untranslated region
US8163480B2 (en) * 2006-10-05 2012-04-24 Quest Diagnostics Investments Incorporated Nucleic acid size detection method

Also Published As

Publication number Publication date
US8697399B2 (en) 2014-04-15
US8163480B2 (en) 2012-04-24
EP2082055B1 (de) 2011-07-06
EP2082055A4 (de) 2010-02-17
AU2007307320B2 (en) 2013-07-11
JP2010505413A (ja) 2010-02-25
MX2009003736A (es) 2009-07-09
WO2008045136A2 (en) 2008-04-17
AU2007307320A1 (en) 2008-04-17
US20080124709A1 (en) 2008-05-29
BRPI0720549A2 (pt) 2014-07-29
WO2008045136A3 (en) 2008-12-11
JP5386357B2 (ja) 2014-01-15
US20100167284A1 (en) 2010-07-01
CA2665723A1 (en) 2008-04-17
CN101595227A (zh) 2009-12-02
EP2082055A2 (de) 2009-07-29

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