ATE515580T1 - Diagnostiche verfahren mit bestimmung von genkopienzahlen und snps im fc rii-fc riii-gen- cluster sowie sonden zur verwendung in solchen verfahren zum nachweis der anfalligkeit für und der behandlungswirksamkeit bei autoimuunkrankheiten - Google Patents

Diagnostiche verfahren mit bestimmung von genkopienzahlen und snps im fc rii-fc riii-gen- cluster sowie sonden zur verwendung in solchen verfahren zum nachweis der anfalligkeit für und der behandlungswirksamkeit bei autoimuunkrankheiten

Info

Publication number
ATE515580T1
ATE515580T1 AT06835684T AT06835684T ATE515580T1 AT E515580 T1 ATE515580 T1 AT E515580T1 AT 06835684 T AT06835684 T AT 06835684T AT 06835684 T AT06835684 T AT 06835684T AT E515580 T1 ATE515580 T1 AT E515580T1
Authority
AT
Austria
Prior art keywords
amount
gene
methods
subject
autoimmuun
Prior art date
Application number
AT06835684T
Other languages
English (en)
Inventor
Dirk Roos
Taco Willem Kuijpers
Original Assignee
Sanquin Bloedvoorziening
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanquin Bloedvoorziening filed Critical Sanquin Bloedvoorziening
Application granted granted Critical
Publication of ATE515580T1 publication Critical patent/ATE515580T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6851—Quantitative amplification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/172—Haplotypes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AT06835684T 2005-12-22 2006-12-22 Diagnostiche verfahren mit bestimmung von genkopienzahlen und snps im fc rii-fc riii-gen- cluster sowie sonden zur verwendung in solchen verfahren zum nachweis der anfalligkeit für und der behandlungswirksamkeit bei autoimuunkrankheiten ATE515580T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP05077984A EP1801234A1 (de) 2005-12-22 2005-12-22 Diagnostische Verfahren, welche die Anzahl von Genkopien und deren Verwendung miteinbeziehen
PCT/NL2006/000662 WO2007073179A2 (en) 2005-12-22 2006-12-22 DIAGNOSTIC METHODS INVOLVING DETERMINING GENE COPY NUMBERS AND SNPs IN THE FcϜRII/FcϜRIII GENE CLUSTER, AND PROBES FOR USE IN SUCH METHODS TO DETECT SUSCEPTIBILITY TO AND TREATMENT EFFICACY IN AUTOIMMUNE DISEASES

Publications (1)

Publication Number Publication Date
ATE515580T1 true ATE515580T1 (de) 2011-07-15

Family

ID=35953866

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06835684T ATE515580T1 (de) 2005-12-22 2006-12-22 Diagnostiche verfahren mit bestimmung von genkopienzahlen und snps im fc rii-fc riii-gen- cluster sowie sonden zur verwendung in solchen verfahren zum nachweis der anfalligkeit für und der behandlungswirksamkeit bei autoimuunkrankheiten

Country Status (10)

Country Link
US (2) US7994300B2 (de)
EP (2) EP1801234A1 (de)
AT (1) ATE515580T1 (de)
AU (1) AU2006327982A1 (de)
CA (1) CA2634692A1 (de)
DK (1) DK1989323T3 (de)
ES (1) ES2369415T3 (de)
PL (1) PL1989323T3 (de)
PT (1) PT1989323E (de)
WO (1) WO2007073179A2 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101652478B (zh) * 2007-10-09 2013-03-27 爱科来株式会社 免疫相关基因的多态性的检测用探针及其用途
EP2055790A1 (de) * 2007-10-30 2009-05-06 Leibniz-Institut für Altersforschung - Fritz-Lipmann-Institut e.V. Kalibriermolekül und Verfahren zur Bestimmung der Anzahl Kopien von Gen-/Zielloci in einem Genom unter Verwendung dieses Kalibriermoleküls
WO2009062051A2 (en) * 2007-11-08 2009-05-14 Pikamab, Inc. Methods and compositions for antibody therapy
CN101910840A (zh) * 2008-01-09 2010-12-08 奥克塔法马有限公司 对免疫球蛋白治疗时出现的nk细胞调节作用有反应者和无反应者的测定和评估方法
WO2010080994A2 (en) * 2009-01-08 2010-07-15 The Uab Research Foundation Process for regulating immune response
JP2013518590A (ja) * 2010-02-02 2013-05-23 アボツト・バイオテクノロジー・リミテツド ＴＮＦ−α阻害剤を用いる処置に対する応答性を予測するための方法および組成物
US20140336950A1 (en) * 2011-11-16 2014-11-13 Univerisity of South Dakota Clustering copy-number values for segments of genomic data
CN118222709B (zh) * 2024-03-25 2025-03-25 南京医科大学 FcγRIIA作为胶质母细胞瘤治疗靶点的应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5830652A (en) * 1994-08-30 1998-11-03 New York Society For The Ruptured And Crippled Maintaining The Hospital For Special Surgery Method for determining predisposition to severe forms of autoimmune disease by determining Fcy receptor allelic patterns
US6905827B2 (en) * 2001-06-08 2005-06-14 Expression Diagnostics, Inc. Methods and compositions for diagnosing or monitoring auto immune and chronic inflammatory diseases
JP2006503587A (ja) * 2002-05-16 2006-02-02 バンダービルト・ユニバーシティ 自己免疫疾患の予測方法
DK1534335T4 (en) * 2002-08-14 2015-10-05 Macrogenics Inc FCGAMMARIIB-SPECIFIC ANTIBODIES AND PROCEDURES FOR USE THEREOF
WO2005113815A2 (en) * 2004-04-26 2005-12-01 Uab Research Foundation Polymorphisms in the fcgr2b promoter and uses thereof

Also Published As

Publication number Publication date
EP1989323B1 (de) 2011-07-06
WO2007073179A3 (en) 2008-01-17
DK1989323T3 (da) 2011-09-26
EP1989323A2 (de) 2008-11-12
PT1989323E (pt) 2011-09-29
WO2007073179A2 (en) 2007-06-28
US8765372B2 (en) 2014-07-01
US20090263795A1 (en) 2009-10-22
US7994300B2 (en) 2011-08-09
CA2634692A1 (en) 2007-06-28
PL1989323T3 (pl) 2011-12-30
AU2006327982A1 (en) 2007-06-28
US20110189672A1 (en) 2011-08-04
ES2369415T3 (es) 2011-11-30
AU2006327982A8 (en) 2008-07-24
EP1801234A1 (de) 2007-06-27

Similar Documents

Publication Publication Date Title
AU2022203322B2 (en) Improved methods of assessing UCH-L1 status in patient samples
Bruggeman et al. Tissue-specific expression of IgG receptors by human macrophages ex vivo
CN110720041B (zh) 用心肌肌钙蛋白i和早期生物标记物帮助诊断和评价人受试者中轻度创伤性脑损伤的方法
AU2018272054B2 (en) Methods for aiding in the determination of whether to perform imaging on a human subject who has sustained or may have sustained an injury to the head using early biomarkers
EP3610268B1 (de) Verfahren zur unterstützung der diagnose und der bestimmung von traumatischen gehirnschäden bei menschen mithilfe frühen biomarkern
US20080166704A1 (en) Method for Quantitative Evaluation of a Rearrangement or a Targeted Genetic Recombination of an Individual and Uses Thereof
JP2020517919A (ja) 同じヒト対象に由来する少なくとも２つの試料に対して早期バイオマーカーを使用する、外傷性脳損傷の超急性の診断及び決定の一助となるための方法
CA3052513A1 (en) Methods for aiding in the diagnosis and determination of the extent of traumatic brain injury in a human subject using the early biomarker ubiquitin carboxy-terminal hydrolase l1
ATE515580T1 (de) Diagnostiche verfahren mit bestimmung von genkopienzahlen und snps im fc rii-fc riii-gen- cluster sowie sonden zur verwendung in solchen verfahren zum nachweis der anfalligkeit für und der behandlungswirksamkeit bei autoimuunkrankheiten
CN113711037A (zh) 抗体效力测定
CN119529089B (zh) 一种抗生长刺激表达基因2蛋白的抗体及其应用
CN110241204A (zh) Sox11作为精神分裂症诊断标记物的应用
US20070231813A1 (en) Fcgr3a Gebotype and Methods for Evaluating Treatment Response to Non-Depleting Antibodies
CN119306830B (zh) 抗皮质醇抗体、检测皮质醇的试剂和试剂盒
KR20140065370A (ko) 대장직장암 마커에 대한 항체
Marantidou et al. Activation-induced cytidine deaminase splicing patterns in chronic lymphocytic leukemia
CA2569196A1 (en) Fcgr3a gebotype and methods for evaluating treatment response to non-depleting antibodies
JP5936223B2 (ja) 慢性閉塞性肺疾患増悪感受性の検査法
US20250104804A1 (en) Systems and methods of developing disease associated antibody sequences
HK40123156A (en) Improved methods of assessing uch-l1 status in patient samples
KR20250175325A (ko) 대상체가 아급성 후천성 뇌손상(abi)을 입었는지, 입었을 가능성이 있는지 또는 입었을 것으로 의심되는지를 결정하기 위한 바이오마커의 용도
JP2023552755A (ja) 頭部コンピュータ断層撮影スキャンの結果が外傷性脳損傷（ｔｂｉ）に関して陰性の対象においてｔｂｉを判定するための１種以上のバイオマーカーの使用
CN116964455A (zh) 用一或多种生物标志物确定已受头部计算机断层扫描且对tbi呈阴性受试者的创伤性脑损伤tbi
Laird et al. Dynamics of CD3γɛ and CD3δɛ dimer expression during murine T cell development

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 1989323

Country of ref document: EP