PT1989323E - Métodos de diagnóstico envolvendo a determinação do número de cópias de genes e snps no grupo de genes fcrii/fcriii e sondas para usar em tais métodos para detecção da susceptibilidade a doenças auto-imunes e eficácia do correspondent - Google Patents
Métodos de diagnóstico envolvendo a determinação do número de cópias de genes e snps no grupo de genes fcrii/fcriii e sondas para usar em tais métodos para detecção da susceptibilidade a doenças auto-imunes e eficácia do correspondent Download PDFInfo
- Publication number
- PT1989323E PT1989323E PT06835684T PT06835684T PT1989323E PT 1989323 E PT1989323 E PT 1989323E PT 06835684 T PT06835684 T PT 06835684T PT 06835684 T PT06835684 T PT 06835684T PT 1989323 E PT1989323 E PT 1989323E
- Authority
- PT
- Portugal
- Prior art keywords
- amount
- subject
- rii
- snps
- probes
- Prior art date
Links
- 208000023275 Autoimmune disease Diseases 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 3
- 108090000623 proteins and genes Proteins 0.000 title abstract 3
- 238000002405 diagnostic procedure Methods 0.000 title abstract 2
- 108091008053 gene clusters Proteins 0.000 title abstract 2
- 239000000523 sample Substances 0.000 title 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 3
- 101000917826 Homo sapiens Low affinity immunoglobulin gamma Fc region receptor II-a Proteins 0.000 abstract 2
- 101000917821 Homo sapiens Low affinity immunoglobulin gamma Fc region receptor II-c Proteins 0.000 abstract 2
- 101000917858 Homo sapiens Low affinity immunoglobulin gamma Fc region receptor III-A Proteins 0.000 abstract 2
- 102100029204 Low affinity immunoglobulin gamma Fc region receptor II-a Human genes 0.000 abstract 2
- 102100029206 Low affinity immunoglobulin gamma Fc region receptor II-c Human genes 0.000 abstract 2
- 102100029193 Low affinity immunoglobulin gamma Fc region receptor III-A Human genes 0.000 abstract 2
- 102100029185 Low affinity immunoglobulin gamma Fc region receptor III-B Human genes 0.000 abstract 2
- 230000004043 responsiveness Effects 0.000 abstract 2
- 101150084286 FCGR2B gene Proteins 0.000 abstract 1
- 101150008832 FCGR3B gene Proteins 0.000 abstract 1
- 101000917824 Homo sapiens Low affinity immunoglobulin gamma Fc region receptor II-b Proteins 0.000 abstract 1
- 101000917839 Homo sapiens Low affinity immunoglobulin gamma Fc region receptor III-B Proteins 0.000 abstract 1
- 108010073807 IgG Receptors Proteins 0.000 abstract 1
- 102100029205 Low affinity immunoglobulin gamma Fc region receptor II-b Human genes 0.000 abstract 1
- 210000004899 c-terminal region Anatomy 0.000 abstract 1
- 230000003247 decreasing effect Effects 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 108010074605 gamma-Globulins Proteins 0.000 abstract 1
- 238000001990 intravenous administration Methods 0.000 abstract 1
- YQYBBVPUXRZFNE-UHFFFAOYSA-N CCC(CC1)CCC1c1ccc(C)cc1 Chemical compound CCC(CC1)CCC1c1ccc(C)cc1 YQYBBVPUXRZFNE-UHFFFAOYSA-N 0.000 description 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6851—Quantitative amplification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/172—Haplotypes
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Analytical Chemistry (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pathology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP05077984A EP1801234A1 (en) | 2005-12-22 | 2005-12-22 | Diagnostic methods involving determining gene copy numbers and use thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT1989323E true PT1989323E (pt) | 2011-09-29 |
Family
ID=35953866
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT06835684T PT1989323E (pt) | 2005-12-22 | 2006-12-22 | Métodos de diagnóstico envolvendo a determinação do número de cópias de genes e snps no grupo de genes fcrii/fcriii e sondas para usar em tais métodos para detecção da susceptibilidade a doenças auto-imunes e eficácia do correspondent |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US7994300B2 (pt) |
| EP (2) | EP1801234A1 (pt) |
| AT (1) | ATE515580T1 (pt) |
| AU (1) | AU2006327982A1 (pt) |
| CA (1) | CA2634692A1 (pt) |
| DK (1) | DK1989323T3 (pt) |
| ES (1) | ES2369415T3 (pt) |
| PL (1) | PL1989323T3 (pt) |
| PT (1) | PT1989323E (pt) |
| WO (1) | WO2007073179A2 (pt) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101652478B (zh) * | 2007-10-09 | 2013-03-27 | 爱科来株式会社 | 免疫相关基因的多态性的检测用探针及其用途 |
| EP2055790A1 (en) * | 2007-10-30 | 2009-05-06 | Leibniz-Institut für Altersforschung - Fritz-Lipmann-Institut e.V. | Calibration molecule and method for determining the number of copies of genes/target loci in a genome using said calibration molecule |
| WO2009062051A2 (en) * | 2007-11-08 | 2009-05-14 | Pikamab, Inc. | Methods and compositions for antibody therapy |
| CN101910840A (zh) * | 2008-01-09 | 2010-12-08 | 奥克塔法马有限公司 | 对免疫球蛋白治疗时出现的nk细胞调节作用有反应者和无反应者的测定和评估方法 |
| WO2010080994A2 (en) * | 2009-01-08 | 2010-07-15 | The Uab Research Foundation | Process for regulating immune response |
| JP2013518590A (ja) * | 2010-02-02 | 2013-05-23 | アボツト・バイオテクノロジー・リミテツド | TNF−α阻害剤を用いる処置に対する応答性を予測するための方法および組成物 |
| US20140336950A1 (en) * | 2011-11-16 | 2014-11-13 | Univerisity of South Dakota | Clustering copy-number values for segments of genomic data |
| CN118222709B (zh) * | 2024-03-25 | 2025-03-25 | 南京医科大学 | FcγRIIA作为胶质母细胞瘤治疗靶点的应用 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5830652A (en) * | 1994-08-30 | 1998-11-03 | New York Society For The Ruptured And Crippled Maintaining The Hospital For Special Surgery | Method for determining predisposition to severe forms of autoimmune disease by determining Fcy receptor allelic patterns |
| US6905827B2 (en) * | 2001-06-08 | 2005-06-14 | Expression Diagnostics, Inc. | Methods and compositions for diagnosing or monitoring auto immune and chronic inflammatory diseases |
| JP2006503587A (ja) * | 2002-05-16 | 2006-02-02 | バンダービルト・ユニバーシティ | 自己免疫疾患の予測方法 |
| DK1534335T4 (en) * | 2002-08-14 | 2015-10-05 | Macrogenics Inc | FCGAMMARIIB-SPECIFIC ANTIBODIES AND PROCEDURES FOR USE THEREOF |
| WO2005113815A2 (en) * | 2004-04-26 | 2005-12-01 | Uab Research Foundation | Polymorphisms in the fcgr2b promoter and uses thereof |
-
2005
- 2005-12-22 EP EP05077984A patent/EP1801234A1/en not_active Withdrawn
-
2006
- 2006-12-22 AT AT06835684T patent/ATE515580T1/de active
- 2006-12-22 EP EP06835684A patent/EP1989323B1/en not_active Not-in-force
- 2006-12-22 US US12/158,623 patent/US7994300B2/en not_active Expired - Fee Related
- 2006-12-22 CA CA002634692A patent/CA2634692A1/en not_active Abandoned
- 2006-12-22 DK DK06835684.9T patent/DK1989323T3/da active
- 2006-12-22 ES ES06835684T patent/ES2369415T3/es active Active
- 2006-12-22 PL PL06835684T patent/PL1989323T3/pl unknown
- 2006-12-22 AU AU2006327982A patent/AU2006327982A1/en not_active Abandoned
- 2006-12-22 PT PT06835684T patent/PT1989323E/pt unknown
- 2006-12-22 WO PCT/NL2006/000662 patent/WO2007073179A2/en not_active Ceased
-
2011
- 2011-02-02 US US13/019,906 patent/US8765372B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP1989323B1 (en) | 2011-07-06 |
| WO2007073179A3 (en) | 2008-01-17 |
| DK1989323T3 (da) | 2011-09-26 |
| EP1989323A2 (en) | 2008-11-12 |
| WO2007073179A2 (en) | 2007-06-28 |
| US8765372B2 (en) | 2014-07-01 |
| US20090263795A1 (en) | 2009-10-22 |
| US7994300B2 (en) | 2011-08-09 |
| CA2634692A1 (en) | 2007-06-28 |
| PL1989323T3 (pl) | 2011-12-30 |
| AU2006327982A1 (en) | 2007-06-28 |
| US20110189672A1 (en) | 2011-08-04 |
| ES2369415T3 (es) | 2011-11-30 |
| ATE515580T1 (de) | 2011-07-15 |
| AU2006327982A8 (en) | 2008-07-24 |
| EP1801234A1 (en) | 2007-06-27 |
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