ATE516014T1 - Neue verwendung, pharmazeutische präparate und verfahren zu ihrer herstellung - Google Patents
Neue verwendung, pharmazeutische präparate und verfahren zu ihrer herstellungInfo
- Publication number
- ATE516014T1 ATE516014T1 AT04789095T AT04789095T ATE516014T1 AT E516014 T1 ATE516014 T1 AT E516014T1 AT 04789095 T AT04789095 T AT 04789095T AT 04789095 T AT04789095 T AT 04789095T AT E516014 T1 ATE516014 T1 AT E516014T1
- Authority
- AT
- Austria
- Prior art keywords
- production
- concentrated
- pharmaceutical preparations
- new use
- supersaturated
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 239000000825 pharmaceutical preparation Substances 0.000 title abstract 2
- HOMGKSMUEGBAAB-UHFFFAOYSA-N ifosfamide Chemical compound ClCCNP1(=O)OCCCN1CCCl HOMGKSMUEGBAAB-UHFFFAOYSA-N 0.000 abstract 2
- 229960001101 ifosfamide Drugs 0.000 abstract 2
- XOGTZOOQQBDUSI-UHFFFAOYSA-M Mesna Chemical compound [Na+].[O-]S(=O)(=O)CCS XOGTZOOQQBDUSI-UHFFFAOYSA-M 0.000 abstract 1
- 229960004635 mesna Drugs 0.000 abstract 1
- 238000007911 parenteral administration Methods 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- XCTFOFPZPRZOFV-UHFFFAOYSA-M sodium;1-sulfanylethanesulfonate Chemical compound [Na+].CC(S)S([O-])(=O)=O XCTFOFPZPRZOFV-UHFFFAOYSA-M 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Dermatology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US50775003P | 2003-10-01 | 2003-10-01 | |
| PCT/US2004/031650 WO2005032515A1 (en) | 2003-10-01 | 2004-09-28 | New use, pharmaceutical preparations as well as a process for their production |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE516014T1 true ATE516014T1 (de) | 2011-07-15 |
Family
ID=34421657
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT04789095T ATE516014T1 (de) | 2003-10-01 | 2004-09-28 | Neue verwendung, pharmazeutische präparate und verfahren zu ihrer herstellung |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US8093230B2 (de) |
| EP (1) | EP1667655B1 (de) |
| JP (2) | JP4886517B2 (de) |
| AT (1) | ATE516014T1 (de) |
| CA (1) | CA2540537A1 (de) |
| CY (1) | CY1111960T1 (de) |
| DK (1) | DK1667655T3 (de) |
| ES (1) | ES2369776T3 (de) |
| PL (1) | PL1667655T3 (de) |
| PT (1) | PT1667655E (de) |
| SI (1) | SI1667655T1 (de) |
| WO (1) | WO2005032515A1 (de) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1958618A1 (de) | 2007-02-15 | 2008-08-20 | Octapharma AG | Verfahren zur Gefriertrocknung mit optimierter Rekonstitution von Biopolymeren |
| EP2994062B1 (de) * | 2013-05-07 | 2019-10-02 | AuXin Surgery SA | Vorrichtung für die ausgabe einer lösung |
| PL3092009T3 (pl) * | 2014-01-06 | 2020-03-31 | Auxin Surgery Sa | Liofilozowane kompozycje mesny |
| BE1024110B1 (fr) * | 2016-10-18 | 2017-11-16 | Auxin Surgery Sa | Dispositif, procédé et formulation pour dissection assistée de manière chimique |
| CA3017403A1 (en) * | 2016-03-14 | 2017-09-21 | Auxin Surgery Sa | Device, method and formulation for chemically assisted dissection |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3732340A (en) * | 1966-07-11 | 1973-05-08 | Asta Werke Ag Chem Fab | N',o-propylene phosphoric acid ester diamides |
| US4220660A (en) * | 1977-12-14 | 1980-09-02 | Asta-werke Aktiengesellschaft, Chemische Farik | Process for the treatment of humans suffering from undesired urotoxic side effects caused by cytostatically active alkylating agents |
| US5204335A (en) * | 1986-10-31 | 1993-04-20 | Asta Pharma Aktiengesellschaft | Ifosfamide lyophilisate and process for its preparation |
| DE3862595D1 (de) * | 1987-03-06 | 1991-06-06 | Asta Pharma Ag | Verfahren zur herstellung von ifosfamid mit verbesserten eigenschaften. |
| DE58900183D1 (de) * | 1988-03-19 | 1991-08-29 | Asta Pharma Ag | Ifosfamid-mesna-lyophilisat und verfahren zu dessen herstellung. |
| US5227373A (en) * | 1991-10-23 | 1993-07-13 | Bristol-Myers Squibb Co. | Lyophilized ifosfamide compositions |
| DE19529057B4 (de) * | 1995-08-08 | 2007-12-13 | Baxter Healthcare S.A. | Ifosfamid-Lyophilisat-Zubereitungen |
| DE19540132C2 (de) | 1995-10-27 | 2003-04-03 | Stada Arzneimittel Ag | Ifosfamid-Lyophilisat |
| EP1453519A4 (de) | 2001-12-13 | 2009-03-11 | Sicor Inc | Wässrige ifosfamid-zusammensetzung |
| US6613927B1 (en) * | 2002-02-08 | 2003-09-02 | American Pharmaceutical Partners, Inc. | Sterile lyophilized ifosfamide and associated methods |
| NZ538584A (en) | 2002-09-05 | 2007-05-31 | Bharat Serums & Vaccines Ltd | Stable liquid composition of oxazaphosphorine, mesna and etherified beta-cyclodextrin |
| US7199111B2 (en) * | 2002-12-02 | 2007-04-03 | Bharat Serums & Vaccines Ltd. | Aqueous ifosfamide compositions for parenteral administration and a process for their preparations |
-
2004
- 2004-09-28 JP JP2006533996A patent/JP4886517B2/ja not_active Expired - Fee Related
- 2004-09-28 CA CA002540537A patent/CA2540537A1/en not_active Abandoned
- 2004-09-28 PL PL04789095T patent/PL1667655T3/pl unknown
- 2004-09-28 PT PT04789095T patent/PT1667655E/pt unknown
- 2004-09-28 AT AT04789095T patent/ATE516014T1/de active
- 2004-09-28 US US10/952,027 patent/US8093230B2/en not_active Expired - Fee Related
- 2004-09-28 SI SI200431734T patent/SI1667655T1/sl unknown
- 2004-09-28 WO PCT/US2004/031650 patent/WO2005032515A1/en not_active Ceased
- 2004-09-28 ES ES04789095T patent/ES2369776T3/es not_active Expired - Lifetime
- 2004-09-28 EP EP04789095A patent/EP1667655B1/de not_active Expired - Lifetime
- 2004-09-28 DK DK04789095.9T patent/DK1667655T3/da active
-
2011
- 2011-04-12 JP JP2011088613A patent/JP2011137048A/ja not_active Withdrawn
- 2011-09-05 CY CY20111100847T patent/CY1111960T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP2007507506A (ja) | 2007-03-29 |
| CY1111960T1 (el) | 2015-11-04 |
| EP1667655B1 (de) | 2011-07-13 |
| HK1091146A1 (en) | 2007-01-12 |
| WO2005032515A1 (en) | 2005-04-14 |
| ES2369776T3 (es) | 2011-12-05 |
| US8093230B2 (en) | 2012-01-10 |
| CA2540537A1 (en) | 2005-04-14 |
| SI1667655T1 (sl) | 2011-10-28 |
| US20050124589A1 (en) | 2005-06-09 |
| PL1667655T3 (pl) | 2012-05-31 |
| JP2011137048A (ja) | 2011-07-14 |
| DK1667655T3 (da) | 2011-10-24 |
| EP1667655A1 (de) | 2006-06-14 |
| PT1667655E (pt) | 2011-08-18 |
| JP4886517B2 (ja) | 2012-02-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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