ATE516047T1 - Ovr110-antikörperzusammensetzungen und anwendungsverfahren - Google Patents
Ovr110-antikörperzusammensetzungen und anwendungsverfahrenInfo
- Publication number
- ATE516047T1 ATE516047T1 AT04760956T AT04760956T ATE516047T1 AT E516047 T1 ATE516047 T1 AT E516047T1 AT 04760956 T AT04760956 T AT 04760956T AT 04760956 T AT04760956 T AT 04760956T AT E516047 T1 ATE516047 T1 AT E516047T1
- Authority
- AT
- Austria
- Prior art keywords
- ovr110
- antibody
- antibodies
- ovr110 antibody
- mammal
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
- C07K16/3069—Reproductive system, e.g. ovaria, uterus, testes, prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6835—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
- A61K47/6851—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a determinant of a tumour cell
- A61K47/6855—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a determinant of a tumour cell the tumour determinant being from breast cancer cell
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6835—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
- A61K47/6851—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a determinant of a tumour cell
- A61K47/6869—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a determinant of a tumour cell the tumour determinant being from a cell of the reproductive system: ovaria, uterus, testes, prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
- C07K16/3015—Breast
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/77—Internalization into the cell
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Cell Biology (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Reproductive Health (AREA)
- Epidemiology (AREA)
- Gynecology & Obstetrics (AREA)
- Oncology (AREA)
- Pregnancy & Childbirth (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US46955503P | 2003-05-09 | 2003-05-09 | |
| US55295904P | 2004-03-12 | 2004-03-12 | |
| US55646404P | 2004-03-25 | 2004-03-25 | |
| PCT/US2004/014490 WO2004101756A2 (en) | 2003-05-09 | 2004-05-10 | Ovr110 antibody compositions and methods of use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE516047T1 true ATE516047T1 (de) | 2011-07-15 |
Family
ID=33458763
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT04760956T ATE516047T1 (de) | 2003-05-09 | 2004-05-10 | Ovr110-antikörperzusammensetzungen und anwendungsverfahren |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US7619068B2 (de) |
| EP (1) | EP1633784B1 (de) |
| JP (1) | JP4884224B2 (de) |
| AT (1) | ATE516047T1 (de) |
| AU (1) | AU2004239301B2 (de) |
| CA (1) | CA2525899C (de) |
| DK (1) | DK1633784T3 (de) |
| IL (1) | IL171797A (de) |
| WO (1) | WO2004101756A2 (de) |
Families Citing this family (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE413466T1 (de) * | 1998-09-02 | 2008-11-15 | Diadexus Inc | Verfahren zur diagnose, bewertung sowie bilddarstellung verschiedener krebserkrankungen |
| US7304149B2 (en) * | 2002-06-20 | 2007-12-04 | Washington University In St. Louis | BTLA nucleic acids |
| WO2004039394A1 (en) | 2002-10-25 | 2004-05-13 | Genentech, Inc. | Novel composition and methods for the treatment of immune related diseases |
| DK1633784T3 (da) * | 2003-05-09 | 2011-10-24 | Diadexus Inc | OVR110 antistofsammensætninger og -anvendelsesfremgangsmåder |
| CA2586313C (en) | 2004-11-10 | 2016-03-08 | Diadexus, Inc. | Ovr110 antibody compositions and methods of use |
| CA2586615C (en) * | 2004-11-12 | 2017-06-27 | Genentech, Inc. | Pro87299 (btla), and variants thereof, for treating immune related disorders |
| EP1841793B1 (de) * | 2005-01-07 | 2010-03-31 | Diadexus, Inc. | Ovr110-antikörperzusammensetzungen und verwendungsverfahren dafür |
| EP3058955B1 (de) | 2005-03-24 | 2019-05-29 | Millennium Pharmaceuticals, Inc. | Ov064-bindende antikörper und verfahren zu deren verwendung |
| US8759490B2 (en) | 2005-03-24 | 2014-06-24 | Millennium Pharamaceuticals, Inc. | Antibodies that bind OV064 and methods of use therefor |
| AU2006321553B2 (en) * | 2005-12-08 | 2012-03-08 | E. R. Squibb & Sons, L.L.C. | Human monoclonal antibodies to O8E |
| CN101473041B (zh) * | 2006-01-04 | 2017-11-14 | 富士瑞必欧美国公司 | He4与其它生化标记物在评估子宫内膜癌和子宫癌中的应用 |
| US8444971B2 (en) * | 2006-11-27 | 2013-05-21 | Diadexus, Inc. | OVR110 antibody compositions and methods of use |
| WO2012019061A2 (en) | 2010-08-05 | 2012-02-09 | Stem Centrx, Inc. | Novel effectors and methods of use |
| CA2809369A1 (en) | 2010-08-27 | 2012-03-01 | Stem Centrx, Inc. | Notum protein modulators and methods of use |
| CA2810016A1 (en) | 2010-09-03 | 2012-03-08 | Stem Centrx, Inc. | Novel modulators and methods of use |
| WO2012118547A1 (en) | 2010-12-08 | 2012-09-07 | Stem Centrx, Inc. | Novel modulators and methods of use |
| SA112330278B1 (ar) | 2011-02-18 | 2015-10-09 | ستيم سينتركس، انك. | مواد ضابطة جديدة وطرق للاستخدام |
| JP6120848B2 (ja) | 2011-08-15 | 2017-04-26 | メディミューン，エルエルシー | 抗ｂ７−ｈ４抗体およびその使用 |
| US20130058947A1 (en) | 2011-09-02 | 2013-03-07 | Stem Centrx, Inc | Novel Modulators and Methods of Use |
| CA2865415C (en) | 2012-02-24 | 2022-06-21 | Stem Centrx, Inc. | Anti sez6 antibodies and methods of use |
| PE20190658A1 (es) | 2012-02-24 | 2019-05-08 | Abbvie Stemcentrx Llc | Moduladores y metodos de empleo novedosos |
| EP2872897B1 (de) | 2012-07-10 | 2017-10-18 | Baxalta GmbH | Anti-mif immunhistochemie |
| AU2013361275B2 (en) | 2012-12-19 | 2016-11-24 | Amplimmune, Inc. | Anti-human B7-H4 antibodies and their uses |
| BR112015019909A2 (pt) | 2013-02-22 | 2017-08-29 | Abbvie Stemcentrx Llc | Conjugados anticorpo-fármaco, composição farmacêutica, usos dos mesmos, e kit |
| US9562099B2 (en) | 2013-03-14 | 2017-02-07 | Genentech, Inc. | Anti-B7-H4 antibodies and immunoconjugates |
| AU2014244424A1 (en) * | 2013-03-14 | 2015-08-27 | Genentech, Inc. | Anti-B7-H4 antibodies and immunoconjugates |
| AU2014312215B2 (en) | 2013-08-28 | 2020-02-27 | Abbvie Stemcentrx Llc | Site-specific antibody conjugation methods and compositions |
| AU2014312310A1 (en) | 2013-08-28 | 2016-04-07 | Abbvie Stemcentrx Llc | Novel SEZ6 modulators and methods of use |
| PE20160870A1 (es) | 2013-11-06 | 2016-09-09 | Abbvie Stemcentrx Llc | Anticuerpos anti-claudina novedosos y metodos de uso |
| PE20161209A1 (es) | 2014-02-21 | 2016-11-10 | Abbvie Stemcentrx Llc | Conjugados de anticuerpos anti-drosophila similar a delta 3 (anti-dll3) y medicamentos para usarse en el tratamiento contra melanoma |
| US9777070B2 (en) | 2014-04-30 | 2017-10-03 | Pfizer Inc | Anti-PTK7 antibody-drug conjugates |
| TW201617368A (zh) | 2014-09-05 | 2016-05-16 | 史坦森特瑞斯公司 | 新穎抗ｍｆｉ２抗體及使用方法 |
| JP6943760B2 (ja) | 2014-09-12 | 2021-10-06 | ジェネンテック， インコーポレイテッド | 抗ｂ７−ｈ４抗体及び免疫複合体 |
| EP3454864A4 (de) | 2016-04-21 | 2021-01-13 | Abbvie Stemcentrx LLC | Neuartige anti-bmpr1b-antikörper und verfahren zur verwendung |
| EP3548515B1 (de) | 2016-12-01 | 2026-01-21 | Regeneron Pharmaceuticals, Inc. | Radioaktiv markierte anti-pd-l1-antikörper für immuno-pet-bildgebung |
| EP3672990A1 (de) | 2017-08-25 | 2020-07-01 | Five Prime Therapeutics, Inc. | B7-h4-antikörper und verfahren zur verwendung davon |
| CN112566934B (zh) | 2018-01-23 | 2024-09-17 | 奈斯科尔公司 | B7-h4抗体及其使用方法 |
| JP2021514379A (ja) | 2018-02-21 | 2021-06-10 | ファイブ プライム セラピューティクス， インコーポレイテッド | Ｂ７−ｈ４抗体製剤 |
| MA52416A (fr) | 2018-03-02 | 2021-04-21 | Five Prime Therapeutics Inc | Anticorps b7-h4 et leurs procédés d'utilisation |
| CN116172059A (zh) * | 2021-11-29 | 2023-05-30 | 内蒙古伊利实业集团股份有限公司 | 青苹果微胶囊、包含其的发酵乳及发酵乳饮料和制备方法 |
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| DK1633784T3 (da) * | 2003-05-09 | 2011-10-24 | Diadexus Inc | OVR110 antistofsammensætninger og -anvendelsesfremgangsmåder |
| US8444971B2 (en) * | 2006-11-27 | 2013-05-21 | Diadexus, Inc. | OVR110 antibody compositions and methods of use |
-
2004
- 2004-05-10 DK DK04760956.5T patent/DK1633784T3/da active
- 2004-05-10 EP EP04760956A patent/EP1633784B1/de not_active Expired - Lifetime
- 2004-05-10 JP JP2006532897A patent/JP4884224B2/ja not_active Expired - Fee Related
- 2004-05-10 US US10/557,331 patent/US7619068B2/en not_active Expired - Lifetime
- 2004-05-10 WO PCT/US2004/014490 patent/WO2004101756A2/en not_active Ceased
- 2004-05-10 AU AU2004239301A patent/AU2004239301B2/en not_active Ceased
- 2004-05-10 CA CA2525899A patent/CA2525899C/en not_active Expired - Lifetime
- 2004-05-10 AT AT04760956T patent/ATE516047T1/de active
-
2005
- 2005-11-06 IL IL171797A patent/IL171797A/en active IP Right Grant
-
2009
- 2009-10-09 US US12/576,313 patent/US20100209438A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO2004101756A3 (en) | 2005-06-09 |
| AU2004239301B2 (en) | 2010-08-19 |
| US20100209438A1 (en) | 2010-08-19 |
| US7619068B2 (en) | 2009-11-17 |
| DK1633784T3 (da) | 2011-10-24 |
| JP2007504280A (ja) | 2007-03-01 |
| JP4884224B2 (ja) | 2012-02-29 |
| CA2525899C (en) | 2016-03-08 |
| EP1633784A2 (de) | 2006-03-15 |
| IL171797A (en) | 2013-08-29 |
| EP1633784B1 (de) | 2011-07-13 |
| AU2004239301A1 (en) | 2004-11-25 |
| WO2004101756A2 (en) | 2004-11-25 |
| CA2525899A1 (en) | 2004-11-25 |
| US20070178101A1 (en) | 2007-08-02 |
| EP1633784A4 (de) | 2006-08-16 |
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