ATE516277T1 - Carbonsäureverbindungen und arzneimittel, die diese verbindungen als wirkstoffe enthalten - Google Patents

Carbonsäureverbindungen und arzneimittel, die diese verbindungen als wirkstoffe enthalten

Info

Publication number: ATE516277T1
Authority: AT; Austria
Prior art keywords: diseases; formula; accompanied; compounds; carboxylic acid
Prior art date: 2002-03-19

Application number

AT03710260T

Other languages

English (en)

Inventor

Maki Iwahashi

Kaoru Kobayashi

Fumio Nambu

Original Assignee

Ono Pharmaceutical Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-03-19

Filing date

2003-03-06

Publication date

2011-07-15

2003-03-06 Application filed by Ono Pharmaceutical Co filed Critical Ono Pharmaceutical Co

2011-07-15 Application granted granted Critical

2011-07-15 Publication of ATE516277T1 publication Critical patent/ATE516277T1/de

Links

150000001875 compounds Chemical class 0.000 title abstract 3
-1 CARBOXYLIC ACID COMPOUNDS Chemical class 0.000 title abstract 2
239000004480 active ingredient Substances 0.000 title 1
229940126601 medicinal product Drugs 0.000 title 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 5
201000010099 disease Diseases 0.000 abstract 3
206010012438 Dermatitis atopic Diseases 0.000 abstract 2
206010061218 Inflammation Diseases 0.000 abstract 2
208000003251 Pruritus Diseases 0.000 abstract 2
208000024780 Urticaria Diseases 0.000 abstract 2
201000008937 atopic dermatitis Diseases 0.000 abstract 2
208000035475 disorder Diseases 0.000 abstract 2
230000004054 inflammatory process Effects 0.000 abstract 2
206010002198 Anaphylactic reaction Diseases 0.000 abstract 1
206010006482 Bronchospasm Diseases 0.000 abstract 1
208000002177 Cataract Diseases 0.000 abstract 1
206010008190 Cerebrovascular accident Diseases 0.000 abstract 1
208000006545 Chronic Obstructive Pulmonary Disease Diseases 0.000 abstract 1
206010009900 Colitis ulcerative Diseases 0.000 abstract 1
206010010744 Conjunctivitis allergic Diseases 0.000 abstract 1
201000004624 Dermatitis Diseases 0.000 abstract 1
208000004262 Food Hypersensitivity Diseases 0.000 abstract 1
206010016946 Food allergy Diseases 0.000 abstract 1
206010063837 Reperfusion injury Diseases 0.000 abstract 1
206010038848 Retinal detachment Diseases 0.000 abstract 1
206010039085 Rhinitis allergic Diseases 0.000 abstract 1
208000006011 Stroke Diseases 0.000 abstract 1
201000008736 Systemic mastocytosis Diseases 0.000 abstract 1
201000006704 Ulcerative Colitis Diseases 0.000 abstract 1
208000002205 allergic conjunctivitis Diseases 0.000 abstract 1
208000026935 allergic disease Diseases 0.000 abstract 1
201000010105 allergic rhinitis Diseases 0.000 abstract 1
230000036783 anaphylactic response Effects 0.000 abstract 1
208000003455 anaphylaxis Diseases 0.000 abstract 1
230000003042 antagnostic effect Effects 0.000 abstract 1
208000006673 asthma Diseases 0.000 abstract 1
208000024998 atopic conjunctivitis Diseases 0.000 abstract 1
208000010668 atopic eczema Diseases 0.000 abstract 1
238000010009 beating Methods 0.000 abstract 1
230000007885 bronchoconstriction Effects 0.000 abstract 1
230000020411 cell activation Effects 0.000 abstract 1
208000026106 cerebrovascular disease Diseases 0.000 abstract 1
230000001684 chronic effect Effects 0.000 abstract 1
235000020932 food allergy Nutrition 0.000 abstract 1
210000003630 histaminocyte Anatomy 0.000 abstract 1
208000015181 infectious disease Diseases 0.000 abstract 1
208000030603 inherited susceptibility to asthma Diseases 0.000 abstract 1
230000000302 ischemic effect Effects 0.000 abstract 1
239000008177 pharmaceutical agent Substances 0.000 abstract 1
208000008423 pleurisy Diseases 0.000 abstract 1
230000002265 prevention Effects 0.000 abstract 1
230000004264 retinal detachment Effects 0.000 abstract 1
206010039073 rheumatoid arthritis Diseases 0.000 abstract 1
238000006748 scratching Methods 0.000 abstract 1
230000002393 scratching effect Effects 0.000 abstract 1
230000035939 shock Effects 0.000 abstract 1
230000009885 systemic effect Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
- C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
- C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D319/20—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring with substituents attached to the hetero ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
- C07D265/34—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
- C07D265/36—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings condensed with one six-membered ring
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/14—Decongestants or antiallergics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/12—Radicals substituted by oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D307/80—Radicals substituted by oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D327/00—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms
- C07D327/02—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms one oxygen atom and one sulfur atom
- C07D327/06—Six-membered rings

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Immunology (AREA)
Pulmonology (AREA)
Dermatology (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Cardiology (AREA)
Hematology (AREA)
Diabetes (AREA)
Heart & Thoracic Surgery (AREA)
Ophthalmology & Optometry (AREA)
Rheumatology (AREA)
Pain & Pain Management (AREA)
Orthopedic Medicine & Surgery (AREA)
Otolaryngology (AREA)
Toxicology (AREA)
Anesthesiology (AREA)
Vascular Medicine (AREA)
Physical Education & Sports Medicine (AREA)
Gastroenterology & Hepatology (AREA)
Transplantation (AREA)
Urology & Nephrology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

AT03710260T 2002-03-19 2003-03-06 Carbonsäureverbindungen und arzneimittel, die diese verbindungen als wirkstoffe enthalten ATE516277T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP2002076456		2002-03-19
PCT/JP2003/002635 WO2003078409A1 (en)	2002-03-19	2003-03-06	Carboxyoic acid compounds and drugs containing the compounds as the active ingredient

Publications (1)

Publication Number	Publication Date
ATE516277T1 true ATE516277T1 (de)	2011-07-15

Family

ID=28035445

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT03710260T ATE516277T1 (de)	2002-03-19	2003-03-06	Carbonsäureverbindungen und arzneimittel, die diese verbindungen als wirkstoffe enthalten

Country Status (18)

Country	Link
US (1)	US7351705B2 (de)
EP (1)	EP1486491B1 (de)
JP (2)	JP4547913B2 (de)
KR (1)	KR20040095302A (de)
CN (1)	CN100378083C (de)
AT (1)	ATE516277T1 (de)
AU (1)	AU2003221325A1 (de)
BR (1)	BR0308518A (de)
CA (1)	CA2479352A1 (de)
ES (1)	ES2365985T3 (de)
IL (1)	IL164094A0 (de)
MX (1)	MXPA04009095A (de)
NO (1)	NO20043894L (de)
NZ (1)	NZ535309A (de)
PL (1)	PL372466A1 (de)
RU (1)	RU2329256C2 (de)
WO (1)	WO2003078409A1 (de)
ZA (1)	ZA200407461B (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU2003297398B2 (en)	2002-12-20	2009-09-24	Amgen Inc.	Asthma and allergic inflammation modulators
AR041089A1 (es)	2003-05-15	2005-05-04	Merck & Co Inc	Procedimiento y composiciones farmaceutiicas para tratar aterosclerosis, dislipidemias y afecciones relacionadas
DK1666473T3 (da) *	2003-09-17	2013-03-25	Ono Pharmaceutical Co	Carboxylsyreforbindelser og medicinske sammensætninger indeholdende samme som aktiv ingrediens
PE20050483A1 (es)	2003-10-31	2005-08-25	Arena Pharm Inc	Derivados de tetrazol de formula (i), sus composiciones farmaceuticas y procesos para producir composiciones farmaceuticas
US20070244107A1 (en) *	2004-08-25	2007-10-18	Waters M Gerard	Method of Treating Atherosclerosis, Dyslipidemias and Related Conditions
CA2586156A1 (en) *	2004-11-04	2006-05-18	Merck & Co., Inc.	Niacin receptor agonists, compositions containing such compounds and methods of treatment
WO2006052798A2 (en) *	2004-11-08	2006-05-18	Merck & Co., Inc.	Method of treating pathological blushing
US20070281969A1 (en) *	2004-11-23	2007-12-06	Colletti Steven L	Niacin Receptor Agonists, Compositions Containing Such Compounds and Methods of Treatment
PE20060949A1 (es)	2004-12-23	2006-10-11	Arena Pharm Inc	Derivados fusionados de pirazol como agonistas del receptor de niacina
WO2006068162A1 (ja) *	2004-12-24	2006-06-29	Shionogi & Co., Ltd.	慢性閉塞性肺疾患の治療剤
US20080139604A1 (en) *	2005-02-17	2008-06-12	Shaun Fitzpatrick	Method of Treating Atherosclerosis, Dyslipidemias and Related Conditions
KR101289995B1 (ko)	2005-09-27	2013-07-26	시오노기 앤드 컴파니, 리미티드	Ｐｇｄ2 수용체 길항제 활성을 갖는 설폰아마이드 유도체
EP2037967B1 (de)	2006-06-16	2016-12-07	The Trustees Of The University Of Pennsylvania	Prostaglandin d2 rezeptor antagonisten zur behandlung androgener alopezie
EP2114154B1 (de) *	2007-02-08	2013-08-28	Merck Sharp & Dohme Corp.	Verfahren zur behandlung von atherosklerose, hyperlipidämien und verwandten erkrankungen
TWI410410B (zh) *	2007-08-10	2013-10-01	Ono Pharmaceutical Co	Phenylacetic acid compounds
GB0721611D0 (en) *	2007-11-02	2007-12-12	Glaxo Group Ltd	Novel compounds
ES2471919T3 (es)	2007-12-19	2014-06-27	Amgen, Inc	Derivados de ácido fenilac�tico como moduladores de inflamación
WO2010030360A1 (en)	2008-09-11	2010-03-18	Arena Pharmaceuticals, Inc.	3H-IMIDAZO[4,5-b]PYRIDIN-5-OL DERIVATIVES USEFUL IN THE TREATMENT OF GPR81 RECEPTOR DISORDERS
PH12012500676A1 (en) *	2009-10-08	2015-06-03	Sanofi Sa	Phenyloxadiazole derivatives as pgds inhibitors
ES2991300T3 (es)	2015-02-13	2024-12-03	Inserm Institut Nat De La Sante Et De Larecherche Medicale	Antagonistas de PTGDR-1 y/o PTGDR-2 para prevenir y/o tratar lupus eritematoso sistémico
IL310383A (en) *	2018-09-20	2024-03-01	Ono Pharmaceutical Co	DP antagonist
WO2020218316A1 (ja) *	2019-04-26	2020-10-29	日産化学株式会社	アリールスルホン酸エステル化合物の製造方法
JP7047954B2 (ja) *	2020-03-19	2022-04-05	小野薬品工業株式会社	フェニル酢酸化合物を含有する医薬組成物
TW202146394A (zh) *	2020-03-19	2021-12-16	日商小野藥品工業股份有限公司	苯乙酸化合物之結晶

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4994479A (en) *	1985-04-03	1991-02-19	Yamanouchi Pharmaceutical Co., Ltd.	Phenylene derivatives and anti-allergic use thereof
IE911919A1 (en) *	1990-06-21	1992-01-01	Zeneca Ltd	Bicyclic heterocyclic compounds
NZ336143A (en)	1996-12-13	2002-05-31	Shionogi & Co	Benzothiophenecarboxamide derivatives and pgd 2 antagonists comprising them
MXPA02008801A (es) *	2000-03-09	2003-07-07	Ono Pharmaceutical Co	Derivados de indol, proceso para la preparacion de los mismos y su uso.

2003
- 2003-03-06 MX MXPA04009095A patent/MXPA04009095A/es active IP Right Grant
- 2003-03-06 US US10/507,885 patent/US7351705B2/en not_active Expired - Fee Related
- 2003-03-06 BR BR0308518-0A patent/BR0308518A/pt not_active IP Right Cessation
- 2003-03-06 ES ES03710260T patent/ES2365985T3/es not_active Expired - Lifetime
- 2003-03-06 IL IL16409403A patent/IL164094A0/xx unknown
- 2003-03-06 JP JP2003576415A patent/JP4547913B2/ja not_active Expired - Fee Related
- 2003-03-06 AU AU2003221325A patent/AU2003221325A1/en not_active Abandoned
- 2003-03-06 CN CNB03811495XA patent/CN100378083C/zh not_active Expired - Fee Related
- 2003-03-06 NZ NZ535309A patent/NZ535309A/en unknown
- 2003-03-06 PL PL03372466A patent/PL372466A1/xx not_active Application Discontinuation
- 2003-03-06 WO PCT/JP2003/002635 patent/WO2003078409A1/ja not_active Ceased
- 2003-03-06 CA CA002479352A patent/CA2479352A1/en not_active Abandoned
- 2003-03-06 EP EP03710260A patent/EP1486491B1/de not_active Expired - Lifetime
- 2003-03-06 RU RU2004130837/04A patent/RU2329256C2/ru not_active IP Right Cessation
- 2003-03-06 AT AT03710260T patent/ATE516277T1/de not_active IP Right Cessation
- 2003-03-06 KR KR10-2004-7014688A patent/KR20040095302A/ko not_active Ceased
2004
- 2004-09-16 ZA ZA200407461A patent/ZA200407461B/en unknown
- 2004-09-17 NO NO20043894A patent/NO20043894L/no not_active Application Discontinuation
2010
- 2010-04-30 JP JP2010105565A patent/JP5168315B2/ja not_active Expired - Fee Related

Also Published As

Publication number	Publication date
JP5168315B2 (ja)	2013-03-21
IL164094A0 (en)	2005-12-18
CN100378083C (zh)	2008-04-02
JPWO2003078409A1 (ja)	2005-07-14
ZA200407461B (en)	2005-07-01
PL372466A1 (en)	2005-07-25
EP1486491A4 (de)	2006-02-15
JP4547913B2 (ja)	2010-09-22
BR0308518A (pt)	2005-02-22
WO2003078409A1 (en)	2003-09-25
CA2479352A1 (en)	2003-09-25
US7351705B2 (en)	2008-04-01
EP1486491A1 (de)	2004-12-15
JP2010189431A (ja)	2010-09-02
AU2003221325A1 (en)	2003-09-29
RU2004130837A (ru)	2005-05-27
KR20040095302A (ko)	2004-11-12
NZ535309A (en)	2006-05-26
ES2365985T3 (es)	2011-10-14
NO20043894L (no)	2004-12-17
EP1486491B1 (de)	2011-07-13
RU2329256C2 (ru)	2008-07-20
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US20050222216A1 (en)	2005-10-06
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Publication	Publication Date	Title
ATE516277T1 (de)	2011-07-15	Carbonsäureverbindungen und arzneimittel, die diese verbindungen als wirkstoffe enthalten
WO2006044732A3 (en)	2006-11-23	2, 6-substituted-4-monosubstitutedamino-pyrimidine as prostaglandin d2 receptor antagonists
JP7221021B2 (ja)	2023-02-13	毒性アルデヒド関連疾患および処置
TNSN07251A1 (en)	2008-12-31	2-phenyl-indoles as prostaglandin d2 receptor antagonists
MX2008011369A (es)	2008-09-18	Compuestos de amino-pirimidina 2,6-sustituidos-4-monosustituidos como antagonistas del receptor de prostaglandina d2.
TNSN08515A1 (en)	2010-04-14	2-phenyl-indoles as prostaglandin d2 receptor antagonists
TNSN08131A1 (en)	2009-07-14	Dihydrogen phosphate salt of a prostaglandin d2 receptor antagonist
ES2396913T3 (es)	2013-03-01	Compuestos moduladores de sirtuina
NO20054878L (no)	2005-10-21	2-Fenoksy- og 2-fenylsulfonamidderivater med CCR3-antagonistisk aktivitet for behandling av astma og andre inflammasjons- eller immunologiske forstyrrelser
WO2005021515A3 (en)	2005-08-25	Inhibitors of phosphodiesterase type-iv
AU2006218403A1 (en)	2006-09-08	Fused heterocyclic compounds and their use as sirtuin modulators
ATE354572T1 (de)	2007-03-15	Substituierte 1-piperidin-4-yl-4-azetidin-3-yl- piperazinderivate und deren verwendung als neurokininantagonisten
CN101277963A (zh)	2008-10-01	作为sirtuin调节剂的噁唑并吡啶衍生物
WO2005051931A3 (en)	2005-10-20	Phosphodiesterase inhibitors
BRPI0414487A (pt)	2006-11-14	composto de ácido carboxìlico e composições medicinais contendo os mesmos como o ingrediente ativo
WO2006085212A3 (en)	2006-10-19	Condensed isoxaline derivatives as inhibitors of phosphodiesterase type-iv
Chen et al.	2017	Design, synthesis and antithrombotic evaluation of novel non-peptide thrombin inhibitors
UA95303C2 (en)	2011-07-25	2-phenyl-indoles as prostaglandin d2 receptor antagonists
UA90319C2 (ru)	2010-04-26	Соединения 2,6-хинолинила и их применение как лекарственного средства
TH84867A (th)	2007-06-07	สารประกอบเฮทเทอโรไซคลิคใหม่ที่เป็นประโยชน์สำหรับการรักษาความผิดปกติทางการอักเสบและทางด้านภูมิแพ้