ATE517341T1 - Interleukin-33 (il-33) zur diagnose und vorhersage von herz-gefäss-erkrankungen - Google Patents
Interleukin-33 (il-33) zur diagnose und vorhersage von herz-gefäss-erkrankungenInfo
- Publication number
- ATE517341T1 ATE517341T1 AT07811859T AT07811859T ATE517341T1 AT E517341 T1 ATE517341 T1 AT E517341T1 AT 07811859 T AT07811859 T AT 07811859T AT 07811859 T AT07811859 T AT 07811859T AT E517341 T1 ATE517341 T1 AT E517341T1
- Authority
- AT
- Austria
- Prior art keywords
- interleukin
- diagnosis
- prediction
- cardiovascular diseases
- pericarditis
- Prior art date
Links
- 102000017761 Interleukin-33 Human genes 0.000 title abstract 4
- 108010067003 Interleukin-33 Proteins 0.000 title abstract 4
- 238000003745 diagnosis Methods 0.000 title abstract 2
- 208000024172 Cardiovascular disease Diseases 0.000 title 1
- 208000004476 Acute Coronary Syndrome Diseases 0.000 abstract 2
- 206010002383 Angina Pectoris Diseases 0.000 abstract 1
- 206010003210 Arteriosclerosis Diseases 0.000 abstract 1
- 206010007572 Cardiac hypertrophy Diseases 0.000 abstract 1
- 208000006029 Cardiomegaly Diseases 0.000 abstract 1
- 206010019280 Heart failures Diseases 0.000 abstract 1
- 208000009525 Myocarditis Diseases 0.000 abstract 1
- 208000010378 Pulmonary Embolism Diseases 0.000 abstract 1
- 208000006011 Stroke Diseases 0.000 abstract 1
- 208000011775 arteriosclerosis disease Diseases 0.000 abstract 1
- 230000002526 effect on cardiovascular system Effects 0.000 abstract 1
- 206010014665 endocarditis Diseases 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 208000010125 myocardial infarction Diseases 0.000 abstract 1
- 208000008494 pericarditis Diseases 0.000 abstract 1
- 238000004393 prognosis Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
- G01N33/6869—Interleukin
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/32—Cardiovascular disorders
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
- Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
- Y10T436/143333—Saccharide [e.g., DNA, etc.]
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Pathology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- General Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Food Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US79547306P | 2006-04-27 | 2006-04-27 | |
| PCT/US2007/067626 WO2007143295A2 (en) | 2006-04-27 | 2007-04-27 | Interleukin-33 (il-33) for the diagnosis and prognosis of cardiovascular disease |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE517341T1 true ATE517341T1 (de) | 2011-08-15 |
Family
ID=38802171
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT07811859T ATE517341T1 (de) | 2006-04-27 | 2007-04-27 | Interleukin-33 (il-33) zur diagnose und vorhersage von herz-gefäss-erkrankungen |
Country Status (4)
| Country | Link |
|---|---|
| US (2) | US20090305265A1 (de) |
| EP (1) | EP2021799B1 (de) |
| AT (1) | ATE517341T1 (de) |
| WO (1) | WO2007143295A2 (de) |
Families Citing this family (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002038794A2 (en) | 2000-11-09 | 2002-05-16 | The Brigham And Women's Hospital, Inc. | Cardiovascular disease diagnostic and therapeutic targets |
| PT3072978T (pt) | 2002-05-09 | 2018-10-15 | Brigham & Womens Hospital Inc | 1l1rl-1 como um marcador de doença cardiovascular |
| ES2529618T3 (es) | 2006-04-24 | 2015-02-23 | Critical Care Diagnostics, Inc. | Predicción de la mortalidad y detección de enfermedades graves |
| EP2021799B1 (de) * | 2006-04-27 | 2011-07-20 | Critical Care Diagnostics, Inc. | Interleukin-33 (il-33) zur diagnose und vorhersage von herz-gefäss-erkrankungen |
| ES2566169T3 (es) | 2006-05-01 | 2016-04-11 | Critical Care Diagnostics, Inc. | Diagnóstico de enfermedad cardiovascular |
| EP3358354B1 (de) | 2008-01-18 | 2020-07-15 | President and Fellows of Harvard College | Verfahren zur detektion von anzeichen einer krankheit oder eines leidens in körperflüssigkeiten |
| DK2660599T3 (en) | 2008-04-18 | 2014-12-08 | Critical Care Diagnostics Inc | PREDICTION OF RISK OF MAJOR ADVERSE HEART EVENTS |
| EP2396425A2 (de) * | 2009-02-13 | 2011-12-21 | Institut National De La Sante Et De La Recherche Medicale | Bakterien-dna als marker für herz-kreislauf- und/oder stoffwechselkrankheit |
| BR112012006105A2 (pt) * | 2009-09-17 | 2016-06-07 | Hoffmann La Roche | painel de múltiplos marcadores de hipertrofia ventricular esquerda. |
| ES2859577T3 (es) | 2010-04-09 | 2021-10-04 | Critical Care Diagnostics Inc | Anticuerpos contra ST-2 humana soluble y ensayos |
| US20130203624A1 (en) | 2010-07-23 | 2013-08-08 | President And Fellows Of Harvard College | Methods of Detecting Prenatal or Pregnancy-Related Diseases or Conditions |
| CA2806293A1 (en) | 2010-07-23 | 2012-01-26 | President And Fellows Of Harvard College | Methods of detecting autoimmune or immune-related diseases or conditions |
| MX382244B (es) | 2010-07-23 | 2025-03-13 | Harvard College | Metodos para detectar firmas de enfermedad o condiciones en fluidos corporales |
| SG10201505724SA (en) | 2010-07-23 | 2015-09-29 | Harvard College | Methods of detecting diseases or conditions using phagocytic cells |
| EP2596349B1 (de) | 2010-07-23 | 2017-12-13 | President and Fellows of Harvard College | Verfahren zum nachweis kardiovaskulärer erkrankungen oder leiden |
| CN103718046B (zh) | 2011-03-17 | 2016-10-12 | 重症监护诊断股份有限公司 | 预测不良临床结果的风险的方法 |
| EP2707524A4 (de) * | 2011-05-12 | 2015-05-06 | Astute Medical Inc | Verfahren und zusammensetzungen zur diagnose und prognose von nierenverletzungen und niereninsuffizienz |
| CA2842072A1 (en) | 2011-07-18 | 2013-01-24 | James V. Snider | Methods of treating cardiovascular diseases and predicting the efficacy of exercise therapy |
| HK1208624A1 (en) | 2012-05-18 | 2016-03-11 | Critical Care Diagnostics, Inc. | Methods for treating or predicting risk of a ventricular tachyarrhythmia event |
| SG11201408383SA (en) | 2012-06-15 | 2015-01-29 | Harry Stylli | Methods of detecting diseases or conditions using circulating diseased cells |
| CN104603289A (zh) | 2012-06-15 | 2015-05-06 | 哈里·斯泰利 | 检测疾病或病状的方法 |
| SG10201704311VA (en) | 2012-08-16 | 2017-07-28 | Critical Care Diagnostics Inc | Methods for predicting risk of developing hypertension |
| HK1212057A1 (en) | 2012-08-21 | 2016-06-03 | 重症监护诊断股份有限公司 | Multimarker risk stratification |
| WO2014164362A1 (en) | 2013-03-09 | 2014-10-09 | Harry Stylli | Methods of detecting prostate cancer |
| EP4202441A3 (de) | 2013-03-09 | 2023-07-26 | Immunis.AI, Inc. | Genexpressionsprofil in makrophagen zur diagnose von krebs |
| JP6649252B2 (ja) * | 2013-10-07 | 2020-02-19 | ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア | アジュバントとしてのインターロイキン−３３を有するワクチン |
| MX2016009060A (es) | 2014-01-10 | 2016-09-09 | Critical Care Diagnostics Inc | Metodos y sistemas para determinar el riesgo de falla cardiaca. |
| US10626464B2 (en) | 2014-09-11 | 2020-04-21 | Cell Mdx, Llc | Methods of detecting prostate cancer |
| CN107109494B (zh) * | 2014-11-10 | 2023-10-27 | 豪夫迈·罗氏有限公司 | Il-33介导型疾病的治疗方法和诊断方法 |
| AU2015346460A1 (en) | 2014-11-10 | 2017-03-23 | Genentech, Inc. | Anti-interleukin-33 antibodies and uses thereof |
| US10079073B2 (en) | 2014-12-11 | 2018-09-18 | Critical Care Diagnostics, Inc. | Test apparatus and methods for ST2 cardiac biomarker |
| US10324089B2 (en) | 2014-12-11 | 2019-06-18 | Critical Care Diagnostics, Inc. | Test apparatus and methods for ST2 cardiac biomarker |
| RU2617060C1 (ru) * | 2015-12-03 | 2017-04-19 | Федеральное государственное бюджетное образовательное учреждение дополнительного профессионального образования "Российская медицинская академия непрерывного профессионального образования" Министерства здравоохранения Российской Федерации (ФГБОУ ДПО РМАНПО Минздрава России) | Способ прогнозирования риска развития инфекционного эндокардита |
| CN108931658A (zh) * | 2018-04-16 | 2018-12-04 | 上海交通大学医学院附属瑞金医院 | 用于诊断心力衰竭合并症及预后评估的血清标记物 |
| US12400762B2 (en) | 2018-12-11 | 2025-08-26 | Eko.Ai Pte. Ltd. | Automatic clinical workflow that recognizes and analyzes 2D and doppler modality echocardiogram images for automated cardiac measurements and diagnosis of cardiac amyloidosis and hypertrophic cardiomyopathy |
| US11446009B2 (en) | 2018-12-11 | 2022-09-20 | Eko.Ai Pte. Ltd. | Clinical workflow to diagnose heart disease based on cardiac biomarker measurements and AI recognition of 2D and doppler modality echocardiogram images |
| US11931207B2 (en) | 2018-12-11 | 2024-03-19 | Eko.Ai Pte. Ltd. | Artificial intelligence (AI) recognition of echocardiogram images to enhance a mobile ultrasound device |
| US12001939B2 (en) | 2018-12-11 | 2024-06-04 | Eko.Ai Pte. Ltd. | Artificial intelligence (AI)-based guidance for an ultrasound device to improve capture of echo image views |
| US12322100B2 (en) | 2018-12-11 | 2025-06-03 | Eko.Ai Pte. Ltd. | Automatic clinical workflow that recognizes and analyzes 2D and doppler modality echocardiogram images for automated cardiac measurements and grading of aortic stenosis severity |
| JP7767298B2 (ja) | 2020-03-13 | 2025-11-11 | ジェネンテック， インコーポレイテッド | 抗インターロイキン－３３抗体及びその使用 |
| CN111549114B (zh) * | 2020-05-13 | 2024-04-09 | 承启医学（深圳）科技有限公司 | 心力衰竭的生物标志物及其应用 |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9211686D0 (en) * | 1992-06-03 | 1992-07-15 | Medisinsk Innovation A S | Chemical compounds |
| US6066322A (en) * | 1995-03-03 | 2000-05-23 | Millennium Pharmaceuticals, Inc. | Methods for the treatment of immune disorders |
| EP2305235A1 (de) * | 1997-04-02 | 2011-04-06 | The Brigham And Women's Hospital, Inc. | Verfahren zur Ermittlung der individualen Risikoprofile atherosklerotischen Erkrankungen |
| EP0988552B1 (de) * | 1997-06-10 | 2010-11-24 | Lpath, Inc. | Verfahren zum frühzeitigen nachweis herzerkrankungen |
| US6323334B1 (en) * | 1999-09-24 | 2001-11-27 | Millennium Pharmaceuticals, Inc. | Nucleic acid molecules encoding a 103 gene product and uses therefor |
| WO2001070817A1 (en) * | 2000-03-21 | 2001-09-27 | Medical & Biological Laboratories Co., Ltd. | Monoclonal antibody and method and kit for the immunoassay of soluble human st2 with the use of the same |
| WO2002038794A2 (en) * | 2000-11-09 | 2002-05-16 | The Brigham And Women's Hospital, Inc. | Cardiovascular disease diagnostic and therapeutic targets |
| US6905827B2 (en) * | 2001-06-08 | 2005-06-14 | Expression Diagnostics, Inc. | Methods and compositions for diagnosing or monitoring auto immune and chronic inflammatory diseases |
| WO2003022987A2 (en) * | 2001-07-26 | 2003-03-20 | Eos Biotechnology, Inc. | Methods of diagnosis of hepatitis c infection, compositions and methods of screening for modulators of hepatitis c infection |
| PT3072978T (pt) * | 2002-05-09 | 2018-10-15 | Brigham & Womens Hospital Inc | 1l1rl-1 como um marcador de doença cardiovascular |
| US20070042978A1 (en) * | 2002-12-19 | 2007-02-22 | Jean-Philippe Girard | Nf-hev compositions and methods of use |
| US20040133079A1 (en) * | 2003-01-02 | 2004-07-08 | Mazar Scott Thomas | System and method for predicting patient health within a patient management system |
| US20060257558A1 (en) * | 2003-10-31 | 2006-11-16 | Hiroshi Nomura | Plasma polymerization of atomically modified surfaces |
| CA2921196C (en) * | 2003-11-26 | 2019-03-05 | Celera Corporation | Single nucleotide polymorphisms associated with cardiovascular disorders and statin response, methods of detection and uses thereof |
| NZ549040A (en) * | 2004-02-17 | 2009-07-31 | Schering Corp | Use for interleukin-33 (IL33) and the IL-33 receptor complex |
| ES2529618T3 (es) * | 2006-04-24 | 2015-02-23 | Critical Care Diagnostics, Inc. | Predicción de la mortalidad y detección de enfermedades graves |
| EP2021799B1 (de) * | 2006-04-27 | 2011-07-20 | Critical Care Diagnostics, Inc. | Interleukin-33 (il-33) zur diagnose und vorhersage von herz-gefäss-erkrankungen |
| ES2566169T3 (es) * | 2006-05-01 | 2016-04-11 | Critical Care Diagnostics, Inc. | Diagnóstico de enfermedad cardiovascular |
| HUE025058T2 (en) * | 2006-05-02 | 2016-01-28 | Critical Care Diagnostics Inc | Differential diagnosis of pulmonary and cardiovascular disease |
| WO2007130627A2 (en) * | 2006-05-04 | 2007-11-15 | The Brigham And Women's Hospital, Inc. | Il-33 in the treatment and diagnosis of diseases and disorders |
| DK2660599T3 (en) * | 2008-04-18 | 2014-12-08 | Critical Care Diagnostics Inc | PREDICTION OF RISK OF MAJOR ADVERSE HEART EVENTS |
| ES2859577T3 (es) * | 2010-04-09 | 2021-10-04 | Critical Care Diagnostics Inc | Anticuerpos contra ST-2 humana soluble y ensayos |
| CN103718046B (zh) * | 2011-03-17 | 2016-10-12 | 重症监护诊断股份有限公司 | 预测不良临床结果的风险的方法 |
| CA2842072A1 (en) * | 2011-07-18 | 2013-01-24 | James V. Snider | Methods of treating cardiovascular diseases and predicting the efficacy of exercise therapy |
| HK1208624A1 (en) * | 2012-05-18 | 2016-03-11 | Critical Care Diagnostics, Inc. | Methods for treating or predicting risk of a ventricular tachyarrhythmia event |
-
2007
- 2007-04-27 EP EP07811859A patent/EP2021799B1/de not_active Not-in-force
- 2007-04-27 WO PCT/US2007/067626 patent/WO2007143295A2/en not_active Ceased
- 2007-04-27 AT AT07811859T patent/ATE517341T1/de not_active IP Right Cessation
- 2007-04-27 US US12/298,613 patent/US20090305265A1/en not_active Abandoned
-
2010
- 2010-11-10 US US12/943,676 patent/US20110053170A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP2021799A2 (de) | 2009-02-11 |
| EP2021799B1 (de) | 2011-07-20 |
| WO2007143295A2 (en) | 2007-12-13 |
| US20110053170A1 (en) | 2011-03-03 |
| WO2007143295A3 (en) | 2008-10-23 |
| EP2021799A4 (de) | 2009-08-05 |
| US20090305265A1 (en) | 2009-12-10 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EP2021799A4 (de) | Interleukin-33 (il-33) zur diagnose und vorhersage von herz-gefäss-erkrankungen | |
| Mocan et al. | Biomarkers of inflammation in left ventricular diastolic dysfunction | |
| Karnik et al. | Epidemiology of atrial fibrillation and heart failure: a growing and important problem | |
| Magnussen et al. | Biomarkers for heart failure: small molecules with high clinical relevance | |
| EP2021796A4 (de) | Diagnose von herz-kreislauf-erkrankung | |
| Widera et al. | Adjustment of the GRACE score by growth differentiation factor 15 enables a more accurate appreciation of risk in non-ST-elevation acute coronary syndrome | |
| WO2008080126A3 (en) | Two biomarkers for diagnosis and monitoring of atherosclerotic cardiovascular disease | |
| MX2009000914A (es) | Medios y metodos para evaluar el riesgo de intervenciones cardiacas basadas en el factor 15 de diferenciacion del crecimiento. | |
| WO2007028070A3 (en) | Use of soluble flt-1 and its fragments in cardiovascular conditions | |
| WO2011072177A3 (en) | Biomarker assay for diagnosis and classification of cardiovascular disease | |
| EA201290629A1 (ru) | Способы и композиции для диагностики и прогнозирования повреждений почек и почечной недостаточности | |
| DK1532269T3 (da) | 1L1RL-1 som markør for kardiovaskulær sygdom | |
| WO2008061149A3 (en) | Methods and compositions for diagnosis and prognosis of renal artery stenosis | |
| NZ597273A (en) | Trimethylamine-containing compounds for diagnosis and prediction of disease | |
| WO2008060607A3 (en) | Methods and compositions for monitoring and risk prediction in cardiorenal syndrome | |
| DE50304023D1 (de) | Diagnose von Myokardinfarkt und akutem Koronarsyndrom durch Kombination von Markern | |
| DE602006017365D1 (de) | Zusammensetzungen für die identifizierung von adenoviren | |
| DK2046951T3 (da) | Proteasesreeningsmetoder og proteaser identificeret dermed | |
| WO2007134028A3 (en) | Biomarkers for depression and methods using the same | |
| ATE485359T1 (de) | Verwendung von grenzflächenaktiven, nicht- enzymatischen proteinen für die textilwäsche | |
| ATE541054T1 (de) | Bio-barcode erkennung für zielmoleküle | |
| WO2009059150A3 (en) | Biomarkers for fatty liver disease and methods using the same | |
| WO2009129454A3 (en) | Predicting risk of major adverse cardiac events | |
| MX2011008323A (es) | Metodos y composiciones para diagnosis y prognosis de lesion renal y falla renal. | |
| EA201000734A1 (ru) | Способ и аппарат для мониторинга пространственного образования фибринового сгустка |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |