ATE517617T1 - Behandlung von parkinson erkrankung mit kape - Google Patents
Behandlung von parkinson erkrankung mit kapeInfo
- Publication number
- ATE517617T1 ATE517617T1 AT02786994T AT02786994T ATE517617T1 AT E517617 T1 ATE517617 T1 AT E517617T1 AT 02786994 T AT02786994 T AT 02786994T AT 02786994 T AT02786994 T AT 02786994T AT E517617 T1 ATE517617 T1 AT E517617T1
- Authority
- AT
- Austria
- Prior art keywords
- kape
- parkinson
- disease
- treatment
- neurodegenerative
- Prior art date
Links
- 208000018737 Parkinson disease Diseases 0.000 title 1
- 208000024172 Cardiovascular disease Diseases 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 208000015122 neurodegenerative disease Diseases 0.000 abstract 1
- 230000000626 neurodegenerative effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/275—Nitriles; Isonitriles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Emergency Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Heart & Thoracic Surgery (AREA)
- Psychiatry (AREA)
- Cardiology (AREA)
- Psychology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US33921501P | 2001-12-10 | 2001-12-10 | |
| PCT/US2002/039458 WO2003053425A1 (en) | 2001-12-10 | 2002-12-10 | Treatment of neurodegenerative and cardiovascular disorders |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE517617T1 true ATE517617T1 (de) | 2011-08-15 |
Family
ID=23328006
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02786994T ATE517617T1 (de) | 2001-12-10 | 2002-12-10 | Behandlung von parkinson erkrankung mit kape |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US20030139458A1 (de) |
| EP (1) | EP1461025B1 (de) |
| JP (1) | JP4511183B2 (de) |
| CN (1) | CN100358515C (de) |
| AT (1) | ATE517617T1 (de) |
| AU (1) | AU2002351341A1 (de) |
| CA (1) | CA2466928A1 (de) |
| TW (1) | TWI335220B (de) |
| WO (1) | WO2003053425A1 (de) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20070208087A1 (en) | 2001-11-02 | 2007-09-06 | Sanders Virginia J | Compounds, compositions and methods for the treatment of inflammatory diseases |
| SI1511710T1 (sl) | 2002-05-31 | 2014-04-30 | Proteotech, Inc. | Spojine, sestavki in postopki za zdravljenje amiloidnih bolezni in sinukleinopatij, kot je Alzheimerjeva bolezen, diabetes tipa 2 in Parkinsova bolezen |
| US20040167217A1 (en) * | 2003-02-26 | 2004-08-26 | Giovanni Scapagnini | Neuroprotective effects of polyphenolic compounds |
| EP1988887A2 (de) * | 2006-01-13 | 2008-11-12 | University of South Carolina | Verfahren und zusammensetzung zur behandlung von morbus parkinson |
| US8058309B2 (en) * | 2006-12-04 | 2011-11-15 | Novotyr Therapeutics Ltd. | Protein kinase modulators and therapeutic uses thereof |
| CA2758016A1 (en) | 2008-06-05 | 2009-12-10 | Novotyr Therapeutics Ltd. | Novel modulators of protein kinase signaling |
| CN101941907B (zh) * | 2010-05-28 | 2015-04-01 | 毛腾淑 | 4-叔丁基苄基-3,4-二羟基肉桂酸酯及其用途和制备方法 |
| WO2012054446A2 (en) * | 2010-10-18 | 2012-04-26 | Chemigen | Combination therapy |
| EP2640376A4 (de) * | 2010-11-15 | 2014-10-01 | Chemigen | Koffeinsäurederivate und ihre verwendung zur verbesserung der neuronalen zelllebensfähigkeit |
| US9770454B2 (en) | 2013-07-14 | 2017-09-26 | Yissum Research Development Company Of The Hebrew University Of Jerusalem, Ltd. | IGF-1R signaling pathway inhibitors useful in the treatment of neurodegenerative diseases |
| ES2808781T3 (es) | 2015-02-05 | 2021-03-01 | Tyrnovo Ltd | Combinaciones de moduladores duales de IRS/STAT3 y agentes anticancerígenos para el tratamiento del cáncer |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2721398A1 (de) * | 1976-05-19 | 1977-12-01 | Ciba Geigy Ag | Alkylphenol-stabilisatoren |
| JPS62294634A (ja) * | 1986-04-11 | 1987-12-22 | ワ−ナ−−ランバ−ト・コンパニ− | ジアリ−ルアルカノイドおよびその製法 |
| US4959503A (en) * | 1986-04-11 | 1990-09-25 | Warner-Lambert Company | Diarylalkanoids having activity as lipoxygenase inhibitors |
| JPH0678286B2 (ja) * | 1988-03-18 | 1994-10-05 | 三井東圧化学株式会社 | ジヒドロカフェイン酸誘導体およびそれを有効成分として含有する治療剤 |
| DE3920616A1 (de) * | 1989-06-23 | 1991-01-03 | Boehringer Mannheim Gmbh | Arzneimittel, enthaltend di-tert.-butylhydroxyphenyl-derivate sowie neue derivate |
| DE4126662A1 (de) * | 1991-08-13 | 1993-02-18 | Boehringer Mannheim Gmbh | Neue 3,5-di-tert.butyl-4-hydroxyphenyl-derivate, verfahren zu ihrer herstellung und arzneimittel |
| WO1997023202A1 (en) * | 1995-12-22 | 1997-07-03 | STATE OF OREGON, acting by and through THE OREGON STATE BOARD OF HIGHER EDUCATION, acting for and on behalf of THE OREGON HEALTH SCIENCES UNIVERSITYA ND THE UNIVERSITY OF OREGON, EUGENE OREGON | Subtype-selective nmda receptor ligands and the use thereof |
| CA2264739C (en) * | 1996-09-05 | 2008-03-18 | Research Development Foundation | Inhibition of nuclear transcription factor nf-kb by caffeic acid phenethyl ester (cape), derivatives of cape, capsaicin (8-methyl-n-vanillyl-6-nonenamide) and resiniferatoxin |
| TW466115B (en) * | 1996-12-10 | 2001-12-01 | American Home Prod | Pharmaceutical composition of antioxidant from equilenin |
| EP0979096B1 (de) * | 1997-02-15 | 2003-05-14 | Millennium Pharmaceuticals, Inc. | Behandlung von infarkten durch inhibierung von nf-kappab |
| GB9801398D0 (en) * | 1998-01-22 | 1998-03-18 | Anggard Erik E | Chemical compounds |
| EP1132093A4 (de) * | 1999-09-17 | 2006-04-19 | Daiichi Suntory Pharma Co Ltd | Vorbeugungsmittel oder heilmittel gegen myokarditis, dilatierte kardiomyopathie und herzinsuffiziens, die nf-kappa b inhibitoren als aktiven bestandteil enthalten |
-
2002
- 2002-12-10 CA CA002466928A patent/CA2466928A1/en not_active Abandoned
- 2002-12-10 AU AU2002351341A patent/AU2002351341A1/en not_active Abandoned
- 2002-12-10 JP JP2003554183A patent/JP4511183B2/ja not_active Expired - Fee Related
- 2002-12-10 EP EP02786994A patent/EP1461025B1/de not_active Expired - Lifetime
- 2002-12-10 TW TW091135703A patent/TWI335220B/zh not_active IP Right Cessation
- 2002-12-10 US US10/316,145 patent/US20030139458A1/en not_active Abandoned
- 2002-12-10 AT AT02786994T patent/ATE517617T1/de not_active IP Right Cessation
- 2002-12-10 CN CNB02823183XA patent/CN100358515C/zh not_active Expired - Fee Related
- 2002-12-10 WO PCT/US2002/039458 patent/WO2003053425A1/en not_active Ceased
-
2010
- 2010-02-18 US US12/708,401 patent/US8575215B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP1461025A4 (de) | 2009-07-29 |
| AU2002351341A1 (en) | 2003-07-09 |
| TW200301100A (en) | 2003-07-01 |
| CA2466928A1 (en) | 2003-07-03 |
| US8575215B2 (en) | 2013-11-05 |
| CN1589137A (zh) | 2005-03-02 |
| TWI335220B (en) | 2011-01-01 |
| JP2005513100A (ja) | 2005-05-12 |
| EP1461025B1 (de) | 2011-07-27 |
| EP1461025A1 (de) | 2004-09-29 |
| US20030139458A1 (en) | 2003-07-24 |
| JP4511183B2 (ja) | 2010-07-28 |
| US20100160433A1 (en) | 2010-06-24 |
| CN100358515C (zh) | 2008-01-02 |
| WO2003053425A1 (en) | 2003-07-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |