ATE518008T1 - System zum zählen von bakterien und zur bestimmung von deren anfälligkeit gegenüber antibiotika - Google Patents
System zum zählen von bakterien und zur bestimmung von deren anfälligkeit gegenüber antibiotikaInfo
- Publication number
- ATE518008T1 ATE518008T1 AT06821599T AT06821599T ATE518008T1 AT E518008 T1 ATE518008 T1 AT E518008T1 AT 06821599 T AT06821599 T AT 06821599T AT 06821599 T AT06821599 T AT 06821599T AT E518008 T1 ATE518008 T1 AT E518008T1
- Authority
- AT
- Austria
- Prior art keywords
- antibiotics
- bacteria
- determining
- suspensibility
- suspended
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M1/00—Apparatus for enzymology or microbiology
- C12M1/34—Measuring or testing with condition measuring or sensing means, e.g. colony counters
- C12M1/3446—Photometry, spectroscopy, laser technology
- C12M1/3453—Opacity, turbidity or light transmission measure; Nephelometry
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/508—Rigid containers without fluid transport within
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
- C12Q1/04—Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
- C12Q1/04—Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
- C12Q1/06—Quantitative determination
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
- C12Q1/04—Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
- C12Q1/10—Enterobacteria
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
- C12Q1/18—Testing for antimicrobial activity of a material
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
- G01N21/03—Cuvette constructions
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
- G01N21/03—Cuvette constructions
- G01N21/0303—Optical path conditioning in cuvettes, e.g. windows; adapted optical elements or systems; path modifying or adjustment
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/47—Scattering, i.e. diffuse reflection
- G01N21/49—Scattering, i.e. diffuse reflection within a body or fluid
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/47—Scattering, i.e. diffuse reflection
- G01N21/49—Scattering, i.e. diffuse reflection within a body or fluid
- G01N21/51—Scattering, i.e. diffuse reflection within a body or fluid inside a container, e.g. in an ampoule
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/487—Physical analysis of biological material of liquid biological material
- G01N33/4875—Details of handling test elements, e.g. dispensing or storage, not specific to a particular test method
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/487—Physical analysis of biological material of liquid biological material
- G01N33/493—Physical analysis of biological material of liquid biological material urine
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/04—Closures and closing means
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0809—Geometry, shape and general structure rectangular shaped
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/06—Investigating concentration of particle suspensions
- G01N15/075—Investigating concentration of particle suspensions by optical means
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
- G01N21/03—Cuvette constructions
- G01N2021/0346—Capillary cells; Microcells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
- G01N21/03—Cuvette constructions
- G01N2021/0389—Windows
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/47—Scattering, i.e. diffuse reflection
- G01N21/49—Scattering, i.e. diffuse reflection within a body or fluid
- G01N21/51—Scattering, i.e. diffuse reflection within a body or fluid inside a container, e.g. in an ampoule
- G01N2021/513—Cuvettes for scattering measurements
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biomedical Technology (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Genetics & Genomics (AREA)
- Toxicology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Medicinal Chemistry (AREA)
- Food Science & Technology (AREA)
- Optics & Photonics (AREA)
- Clinical Laboratory Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Sustainable Development (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US59739505P | 2005-11-29 | 2005-11-29 | |
| GB0615692A GB2432660A (en) | 2005-11-29 | 2006-08-08 | System for counting bacteria and determining their susceptibility to antibiotics |
| PCT/IL2006/001379 WO2007063543A2 (en) | 2005-11-29 | 2006-11-29 | System for counting bacteria and determining their susceptibility to antibiotics |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE518008T1 true ATE518008T1 (de) | 2011-08-15 |
Family
ID=37027384
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT06821599T ATE518008T1 (de) | 2005-11-29 | 2006-11-29 | System zum zählen von bakterien und zur bestimmung von deren anfälligkeit gegenüber antibiotika |
Country Status (6)
| Country | Link |
|---|---|
| US (6) | US8339601B2 (de) |
| EP (1) | EP1960532B1 (de) |
| AT (1) | ATE518008T1 (de) |
| ES (1) | ES2370659T3 (de) |
| GB (2) | GB2432660A (de) |
| WO (1) | WO2007063543A2 (de) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2432660A (en) | 2005-11-29 | 2007-05-30 | Bacterioscan Ltd | System for counting bacteria and determining their susceptibility to antibiotics |
| CA3138078C (en) | 2007-10-02 | 2024-02-13 | Labrador Diagnostics Llc | Modular point-of-care devices and uses thereof |
| FR2963103B1 (fr) * | 2010-07-22 | 2012-08-24 | Commissariat Energie Atomique | Procede d'estimation de la quantite d'entites deposees sur des microparticules en suspension dans une solution, dispositif associe et utilisation de ce dispositif |
| MX349288B (es) | 2011-01-21 | 2017-07-21 | Theranos Inc | Sistemas y metodos para maximizacion de uso de muestras. |
| US9632102B2 (en) | 2011-09-25 | 2017-04-25 | Theranos, Inc. | Systems and methods for multi-purpose analysis |
| US20140170735A1 (en) | 2011-09-25 | 2014-06-19 | Elizabeth A. Holmes | Systems and methods for multi-analysis |
| US8475739B2 (en) | 2011-09-25 | 2013-07-02 | Theranos, Inc. | Systems and methods for fluid handling |
| US9810704B2 (en) | 2013-02-18 | 2017-11-07 | Theranos, Inc. | Systems and methods for multi-analysis |
| US10012664B2 (en) | 2011-09-25 | 2018-07-03 | Theranos Ip Company, Llc | Systems and methods for fluid and component handling |
| US20160054343A1 (en) * | 2013-02-18 | 2016-02-25 | Theranos, Inc. | Systems and methods for multi-analysis |
| EP3077796B1 (de) | 2013-12-06 | 2024-09-18 | IP Specialists Ltd. | Optische messungen von flüssigkeiten mit freier oberfläche |
| JP6479037B2 (ja) | 2013-12-06 | 2019-03-06 | バクテリオスキャン エルティーディー | 試料チャンバを有する光学測定キュベット |
| US20170016831A1 (en) * | 2014-02-28 | 2017-01-19 | Empire Technology Development Llc | Systems and methods for determining concentration of a component in a fluid sample |
| EP3227664B1 (de) | 2014-12-05 | 2020-09-16 | Bacterioscan Ltd. | Mehfachabtastendes laserstreuungsmessinstrument mit inkubationsfunktion und systeme zur verwendung davon |
| US10233481B2 (en) | 2014-12-05 | 2019-03-19 | Bacterioscan Ltd | Multi-sample laser-scatter measurement instrument with incubation feature and systems for using the same |
| US20160161404A1 (en) | 2014-12-05 | 2016-06-09 | Bacterioscan Ltd | System Using Laser-Scatter Measurement Instrument For Organism Identification And Related Network |
| US10065184B2 (en) | 2014-12-30 | 2018-09-04 | Bacterioscan Ltd. | Pipette having integrated filtration assembly |
| JP2018503842A (ja) | 2015-01-26 | 2018-02-08 | バクテリオスキャン エルティーディー | 回転木馬式流体サンプル配置を呈するレーザ散乱計測器具 |
| JP6941939B2 (ja) * | 2016-12-22 | 2021-09-29 | リンテック株式会社 | 検査部材、および検査部材の製造方法 |
| WO2018187548A2 (en) * | 2017-04-05 | 2018-10-11 | Arizona Board Of Regents On Behalf Of Arizona State University | Antimicrobial susceptibility testing with large-volume light scattering imaging and deep learning video microscopy |
| WO2019023320A1 (en) * | 2017-07-25 | 2019-01-31 | Arizona Board Of Regents On Behalf Of Arizona State University | FAST ANTIBIOTIC SENSITIVITY TESTING BY MONITORING THE SUBMICRON SCALE MOVEMENT OF SIMPLE BACTERIAL CELLS |
| WO2019050847A1 (en) * | 2017-09-05 | 2019-03-14 | Nongjian Tao | RAPID DETECTION OF BACTERIA AND ANTIBIOTIC SENSITIVITY TESTING BY PRECISION MONITORING OF BACTERIAL CELLS |
| ES2822915T3 (es) * | 2017-12-11 | 2021-05-05 | Uponor Oyj | Detección de objetos microscópicos en fluidos |
| WO2019227070A1 (en) * | 2018-05-25 | 2019-11-28 | Boards Of Regents Of The University Of Texas Systems | Systems and methods for detecting contaminants |
| US11215840B2 (en) | 2018-10-18 | 2022-01-04 | International Business Machines Corporation | Testing a biological sample based on sample spectrography and machine learning techniques |
| WO2020106887A2 (en) | 2018-11-21 | 2020-05-28 | BacterioScan, Inc. | Systems and methods using bacteriophage-mediated lysis for detection and identification of microorganisms in a fluid sample |
| US11099121B2 (en) | 2019-02-05 | 2021-08-24 | BacterioScan Inc. | Cuvette device for determining antibacterial susceptibility |
| GB202001397D0 (en) * | 2020-01-31 | 2020-03-18 | Odx Innovations Ltd | Apparatus, system and method for measuring properties of a sample |
| WO2021158700A1 (en) * | 2020-02-03 | 2021-08-12 | The Penn State Research Foundation | Systems and methods for antibacterial susceptibility testing using dynamic laser speckle imaging |
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| US20070206203A1 (en) * | 2004-04-10 | 2007-09-06 | Michael Trainer | Methods and Apparatus for Determining Particle Characteristics by Measuring Scattered Light |
| US20050210996A1 (en) * | 2004-03-12 | 2005-09-29 | Quinn John G | Flow channel structure and method |
| GB2412166B (en) | 2004-03-17 | 2006-03-29 | Univ Sheffield Hallam | Method and apparatus for particle analysis |
| CN100595564C (zh) * | 2004-07-30 | 2010-03-24 | 百维吉伦特系统有限公司 | 病原体和粒子检测器系统和方法 |
| AU2005273482B2 (en) * | 2004-08-16 | 2010-12-16 | Bacterioscan | Detection of bacteria in fluids |
| US7557930B2 (en) | 2004-11-23 | 2009-07-07 | Lockheed Martin Corporation | Bessel beam interferometer and measurement method |
| MX2007009124A (es) | 2005-01-31 | 2007-10-08 | Univ Illinois | Metodos y dispositivos para caracterizar particulas en medios transparentes y turbios. |
| US20080106737A1 (en) | 2005-08-16 | 2008-05-08 | Amnon Weichselbaum | Detecting and counting bacteria suspended in biological fluids |
| US7518723B2 (en) * | 2005-09-19 | 2009-04-14 | Jmar Technologies, Inc. | Systems and methods for detecting radiation, biotoxin, chemical, and biological warfare agents using a multiple angle light scattering (MALS) instrument |
| GB2432660A (en) | 2005-11-29 | 2007-05-30 | Bacterioscan Ltd | System for counting bacteria and determining their susceptibility to antibiotics |
| CN101000306B (zh) | 2006-01-09 | 2010-11-17 | 深圳迈瑞生物医疗电子股份有限公司 | 细胞分析仪 |
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2006
- 2006-08-08 GB GB0615692A patent/GB2432660A/en not_active Withdrawn
- 2006-11-29 WO PCT/IL2006/001379 patent/WO2007063543A2/en not_active Ceased
- 2006-11-29 ES ES06821599T patent/ES2370659T3/es active Active
- 2006-11-29 US US12/085,708 patent/US8339601B2/en active Active
- 2006-11-29 AT AT06821599T patent/ATE518008T1/de not_active IP Right Cessation
- 2006-11-29 EP EP06821599A patent/EP1960532B1/de active Active
-
2008
- 2008-04-07 GB GBGB0806266.3A patent/GB0806266D0/en not_active Ceased
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2012
- 2012-11-29 US US13/689,000 patent/US20130089476A1/en not_active Abandoned
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2014
- 2014-12-19 US US14/577,750 patent/US9395297B2/en active Active
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2016
- 2016-06-16 US US15/183,969 patent/US9958384B2/en active Active
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2018
- 2018-04-10 US US15/949,854 patent/US10222328B2/en active Active
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2019
- 2019-03-04 US US16/291,145 patent/US10724949B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| WO2007063543A3 (en) | 2009-04-16 |
| US20180231463A1 (en) | 2018-08-16 |
| GB0615692D0 (en) | 2006-09-13 |
| EP1960532A4 (de) | 2009-10-28 |
| US20160299067A1 (en) | 2016-10-13 |
| US20150131095A1 (en) | 2015-05-14 |
| US20130089476A1 (en) | 2013-04-11 |
| ES2370659T3 (es) | 2011-12-21 |
| EP1960532A2 (de) | 2008-08-27 |
| US9958384B2 (en) | 2018-05-01 |
| US10724949B2 (en) | 2020-07-28 |
| GB0806266D0 (en) | 2008-05-14 |
| GB2432660A (en) | 2007-05-30 |
| US20090325210A1 (en) | 2009-12-31 |
| US8339601B2 (en) | 2012-12-25 |
| US9395297B2 (en) | 2016-07-19 |
| WO2007063543A2 (en) | 2007-06-07 |
| US20190195791A1 (en) | 2019-06-27 |
| EP1960532B1 (de) | 2011-07-27 |
| US10222328B2 (en) | 2019-03-05 |
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