ATE518544T1 - Rotbusch-extrakt gegen diabetes - Google Patents
Rotbusch-extrakt gegen diabetesInfo
- Publication number
- ATE518544T1 ATE518544T1 AT08717608T AT08717608T ATE518544T1 AT E518544 T1 ATE518544 T1 AT E518544T1 AT 08717608 T AT08717608 T AT 08717608T AT 08717608 T AT08717608 T AT 08717608T AT E518544 T1 ATE518544 T1 AT E518544T1
- Authority
- AT
- Austria
- Prior art keywords
- diabetes
- diabetic agent
- diabetic
- extract against
- aspalathin
- Prior art date
Links
- 206010012601 diabetes mellitus Diseases 0.000 title abstract 4
- 239000003472 antidiabetic agent Substances 0.000 abstract 5
- 229940125708 antidiabetic agent Drugs 0.000 abstract 4
- 239000000203 mixture Substances 0.000 abstract 3
- 240000006914 Aspalathus linearis Species 0.000 abstract 2
- JMGZEFIQIZZSBH-UHFFFAOYSA-N Bioquercetin Natural products CC1OC(OCC(O)C2OC(OC3=C(Oc4cc(O)cc(O)c4C3=O)c5ccc(O)c(O)c5)C(O)C2O)C(O)C(O)C1O JMGZEFIQIZZSBH-UHFFFAOYSA-N 0.000 abstract 2
- VCPUQYKWJRESOC-VJXVFPJBSA-N aspalathin Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1C1=C(O)C=C(O)C(C(=O)CCC=2C=C(O)C(O)=CC=2)=C1O VCPUQYKWJRESOC-VJXVFPJBSA-N 0.000 abstract 2
- VCPUQYKWJRESOC-UHFFFAOYSA-N aspalathine Natural products OC1C(O)C(O)C(CO)OC1C1=C(O)C=C(O)C(C(=O)CCC=2C=C(O)C(O)=CC=2)=C1O VCPUQYKWJRESOC-UHFFFAOYSA-N 0.000 abstract 2
- IVTMALDHFAHOGL-UHFFFAOYSA-N eriodictyol 7-O-rutinoside Natural products OC1C(O)C(O)C(C)OC1OCC1C(O)C(O)C(O)C(OC=2C=C3C(C(C(O)=C(O3)C=3C=C(O)C(O)=CC=3)=O)=C(O)C=2)O1 IVTMALDHFAHOGL-UHFFFAOYSA-N 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- FDRQPMVGJOQVTL-UHFFFAOYSA-N quercetin rutinoside Natural products OC1C(O)C(O)C(CO)OC1OCC1C(O)C(O)C(O)C(OC=2C(C3=C(O)C=C(O)C=C3OC=2C=2C=C(O)C(O)=CC=2)=O)O1 FDRQPMVGJOQVTL-UHFFFAOYSA-N 0.000 abstract 2
- IKGXIBQEEMLURG-BKUODXTLSA-N rutin Chemical compound O[C@H]1[C@H](O)[C@@H](O)[C@H](C)O[C@@H]1OC[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](OC=2C(C3=C(O)C=C(O)C=C3OC=2C=2C=C(O)C(O)=CC=2)=O)O1 IKGXIBQEEMLURG-BKUODXTLSA-N 0.000 abstract 2
- ALABRVAAKCSLSC-UHFFFAOYSA-N rutin Natural products CC1OC(OCC2OC(O)C(O)C(O)C2O)C(O)C(O)C1OC3=C(Oc4cc(O)cc(O)c4C3=O)c5ccc(O)c(O)c5 ALABRVAAKCSLSC-UHFFFAOYSA-N 0.000 abstract 2
- 235000005493 rutin Nutrition 0.000 abstract 2
- 229960004555 rutoside Drugs 0.000 abstract 2
- 241001219293 Aspalathus Species 0.000 abstract 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 abstract 1
- 208000002705 Glucose Intolerance Diseases 0.000 abstract 1
- 230000003178 anti-diabetic effect Effects 0.000 abstract 1
- 235000013361 beverage Nutrition 0.000 abstract 1
- 239000008280 blood Substances 0.000 abstract 1
- 210000004369 blood Anatomy 0.000 abstract 1
- 230000003247 decreasing effect Effects 0.000 abstract 1
- 239000008103 glucose Substances 0.000 abstract 1
- 201000009104 prediabetes syndrome Diseases 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 208000001072 type 2 diabetes mellitus Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7004—Monosaccharides having only carbon, hydrogen and oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Medical Informatics (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Alternative & Traditional Medicine (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US89425807P | 2007-03-12 | 2007-03-12 | |
| PCT/EP2008/052861 WO2008110551A1 (en) | 2007-03-12 | 2008-03-11 | An anti-diabetic extract of rooibos |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE518544T1 true ATE518544T1 (de) | 2011-08-15 |
Family
ID=39495123
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT08717608T ATE518544T1 (de) | 2007-03-12 | 2008-03-11 | Rotbusch-extrakt gegen diabetes |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US8877717B2 (de) |
| EP (2) | EP2120980B1 (de) |
| JP (1) | JP2010520913A (de) |
| CN (1) | CN101765433A (de) |
| AT (1) | ATE518544T1 (de) |
| ES (1) | ES2371393T3 (de) |
| WO (1) | WO2008110551A1 (de) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2053050B1 (de) † | 2007-10-23 | 2011-08-31 | Kneipp-Werke Kneipp-Mittel-Zentrale GmbH & Co. KG | Aspalathin-ähnliches Dihydrochalcon und Verfahren zur Herstellung |
| WO2011120576A1 (en) * | 2010-03-31 | 2011-10-06 | Zadec | Antidiabetic enolic glucoside of phenylpyruvic acid |
| ES2526660T3 (es) * | 2010-10-07 | 2015-01-14 | Zadec Aps | Glucósido enólico de ácido fenilpirúvico antidiabético |
| JP2016026208A (ja) * | 2015-10-28 | 2016-02-12 | サズセ アーペーエスZadec Aps | フェニルピルビン酸の抗糖尿病エノール型グルコシド |
| JP6297621B2 (ja) * | 2016-06-08 | 2018-03-20 | サズセ アーペーエスZadec Aps | フェニルピルビン酸の抗糖尿病エノール型グルコシド |
| CN107998220B (zh) * | 2016-10-31 | 2020-09-18 | 亚宝药业集团股份有限公司 | 一种用于减少食物摄取、延迟饥饿感、控制体重的组合物 |
| JP2018087233A (ja) * | 2018-02-21 | 2018-06-07 | サズセ アーペーエスZadec Aps | フェニルピルビン酸の抗糖尿病エノール型グルコシド |
Family Cites Families (46)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4062950A (en) | 1973-09-22 | 1977-12-13 | Bayer Aktiengesellschaft | Amino sugar derivatives |
| DE2719912C3 (de) | 1977-05-04 | 1979-12-06 | Bayer Ag, 5090 Leverkusen | Verfahren zur Isolierung von 0- |4,6-Dideoxy-4- [JJl S-O,4,6/5)-4,5,6-trihydroxy-3-hydroxymethyl-2cyclohexen-1-yl] -amino] - a -D-glucopyranosyl} -(I Pfeil nach rechts 4)-0- a D-glucopyranosyl-(l Pfeil nach rechts 4)-D-glucopyranose aus Kulturbrühen |
| US4130714A (en) | 1977-05-23 | 1978-12-19 | Pfizer Inc. | Hydantoin therapeutic agents |
| NO154918C (no) | 1977-08-27 | 1987-01-14 | Bayer Ag | Analogifremgangsmaate til fremstilling av terapeutisk aktive derivater av 3,4,5-trihydroksypiperidin. |
| JPS5953920B2 (ja) | 1977-12-28 | 1984-12-27 | 東洋醸造株式会社 | 新規なアミノ糖化合物およびその製法 |
| IE47592B1 (en) | 1977-12-29 | 1984-05-02 | Ici Ltd | Enzyme inhibitory phthalazin-4-ylacetic acid derivatives, pharmaceutical compositions thereof,and process for their manufacture |
| JPS5745185A (en) | 1980-07-21 | 1982-03-13 | Eisai Co Ltd | Hydantoin derivative and its preparation |
| US4791126A (en) | 1980-08-22 | 1988-12-13 | Ono Pharmaceutical Co., Ltd. | Rhodanine derivatives, process for their preparation, and aldose reductase inhibitor containing the rhodanine derivatives as active ingredients |
| JPS5740478A (en) | 1980-08-22 | 1982-03-06 | Ono Pharmaceut Co Ltd | Rhodanine derivative, its preparation and aldose reductase inhibitor containing rhodanine derivative |
| EP0056194B1 (de) | 1981-01-05 | 1984-09-12 | Takeda Chemical Industries, Ltd. | N-substituierte Pseudo-Aminozucker, ihre Herstellung und Verwendung |
| CA1176269A (en) | 1981-03-02 | 1984-10-16 | Kazimir Sestanj | N-naphthoylglycine derivatives |
| US4438272A (en) | 1982-04-15 | 1984-03-20 | Alcon Laboratories, Inc. | Spiro-(fluoren-9,4'-imidazolidine)-2',5'-diones |
| US4436745A (en) | 1982-04-15 | 1984-03-13 | Alcon Laboratories, Inc. | Method of inhibiting aldose reductase activity |
| US5066659A (en) | 1984-10-30 | 1991-11-19 | Pfizer Inc. | Spiro-heteroazalones for treatment of diabetic complications |
| US4634765A (en) | 1984-12-18 | 1987-01-06 | Merrell Dow Pharmaceuticals Inc. | Homodisaccharide hypoglycemic agents |
| GB8524663D0 (en) | 1985-10-07 | 1985-11-13 | Fujisawa Pharmaceutical Co | Quinazoline derivatives |
| AU602641B2 (en) | 1986-04-17 | 1990-10-18 | Senju Pharmaceutical Co., Ltd. | Thiolactam-N-acetic acid derivatives, their production and use |
| DE3769066D1 (de) | 1986-08-28 | 1991-05-08 | Sanwa Kagaku Kenkyusho Co | Hydantoin-derivate zur behandlung von komplikationen bei diabetes. |
| US5192772A (en) | 1987-12-09 | 1993-03-09 | Nippon Shinyaku Co. Ltd. | Therapeutic agents |
| GB8801037D0 (en) | 1988-01-18 | 1988-02-17 | Plessey Co Ltd | Improvements relating to fuel supply systems |
| US5252572A (en) | 1988-02-03 | 1993-10-12 | Chinoin Gyogyszer- Es Vegyeszeti Termekek Gyara Rt. | Pyridopyrimidine derivatives, pharmaceutical compositions containing them and process for preparing same |
| EP0344383A1 (de) | 1988-06-02 | 1989-12-06 | Merrell Dow Pharmaceuticals Inc. | Alpha-Glucosidase-Inhibitoren |
| DE3836675A1 (de) | 1988-10-28 | 1990-05-03 | Hoechst Ag | Glykosidase-inhibitor salbostatin, verfahren zu seiner herstellung und seine verwendung |
| US4980357A (en) | 1990-03-01 | 1990-12-25 | Pfizer Inc. | Azolidinedione derivatives |
| US5037831A (en) | 1990-05-21 | 1991-08-06 | American Home Products Corporation | Spiro-isoquinoline-pyrrolidines and analogs thereof useful as aldose reductase inhibitors |
| US5504078A (en) | 1990-06-08 | 1996-04-02 | Merrell Dow Pharmaceuticals Inc. | α-glucosidase inhibitors |
| GB9016978D0 (en) | 1990-08-02 | 1990-09-19 | Ici Plc | Acetamide derivatives |
| US5217877A (en) | 1990-09-28 | 1993-06-08 | Bristol-Myers Squibb Company | Process for the preparation of α-glucosidase inhibitor, pradimicin Q |
| US5091418A (en) | 1990-09-28 | 1992-02-25 | Bristol-Myers Squibb Company | Novel alpha-glucosidase inhibitor, pradimicin Q |
| JP2724524B2 (ja) | 1992-03-06 | 1998-03-09 | 株式会社ユニエ | 便秘改善・治療剤 |
| JPH06199695A (ja) * | 1992-03-06 | 1994-07-19 | Yunie:Kk | 糖尿病改善治療剤 |
| JPH05246875A (ja) * | 1992-03-06 | 1993-09-24 | Ruibosuteii Japan:Kk | 糖尿病改善治療剤 |
| KR950703539A (ko) | 1992-09-28 | 1995-09-20 | 알렌 제이. 스피겔 | 당뇨병 합병증 치료용 치환된 피리미딘(substituted pyrimidines for control or diabetic complications) |
| JP3290834B2 (ja) * | 1994-11-25 | 2002-06-10 | 昌俊 中野 | 抗ウィルス剤並びにその製造方法 |
| CA2224062C (en) | 1995-06-06 | 2001-09-04 | Pfizer Limited | Substituted n-(indole-2-carbonyl)-glycinamides and derivatives as glycogen phosphorylase inhibitors |
| CA2223625C (en) | 1995-06-06 | 2003-06-03 | Pfizer Inc. | Substituted n-(indole-2-carbonyl-) amides and derivatives as glycogen phosphorylase inhibitors |
| TW432073B (en) | 1995-12-28 | 2001-05-01 | Pfizer | Pyrazolopyridine compounds |
| US6251902B1 (en) | 1997-06-25 | 2001-06-26 | Pfizer Inc. | Dipeptide derivatives as growth hormone secretagogues |
| KR20000019716A (ko) * | 1998-09-15 | 2000-04-15 | 박호군 | 바이오플라보노이드 화합물을 포함하는 혈당 강하용 조성물 |
| DE10118695A1 (de) | 2001-04-14 | 2002-10-17 | Helmut Eisemann | Getränk und Verfahren zur Herstellung eines Getränks |
| JP2003171305A (ja) * | 2001-11-30 | 2003-06-20 | Yunie:Kk | 糖尿病改善治療剤 |
| US6572897B1 (en) | 2002-07-03 | 2003-06-03 | Vitacost.Com, Inc. | Insulin sensitivity maintenance and blood sugar level maintenance formulation for the prevention and treatment of diabetes |
| KR100749653B1 (ko) | 2003-07-25 | 2007-08-14 | 닛코킨조쿠 가부시키가이샤 | 고순도 하프늄 재료, 이 재료로 이루어진 타겟트 및 박막과고순도 하프늄의 제조방법 |
| JP2007070263A (ja) * | 2005-09-05 | 2007-03-22 | Oriza Yuka Kk | 糖尿病予防用組成物 |
| JP5124152B2 (ja) * | 2007-03-05 | 2013-01-23 | タマ生化学株式会社 | すい臓β細胞インスリン分泌能促進剤および体内組織細胞グルコース取り込み能促進剤 |
| EP2053050B1 (de) | 2007-10-23 | 2011-08-31 | Kneipp-Werke Kneipp-Mittel-Zentrale GmbH & Co. KG | Aspalathin-ähnliches Dihydrochalcon und Verfahren zur Herstellung |
-
2008
- 2008-03-11 EP EP08717608A patent/EP2120980B1/de not_active Not-in-force
- 2008-03-11 US US12/531,035 patent/US8877717B2/en not_active Expired - Fee Related
- 2008-03-11 ES ES08717608T patent/ES2371393T3/es active Active
- 2008-03-11 CN CN200880013877A patent/CN101765433A/zh active Pending
- 2008-03-11 EP EP11170057A patent/EP2368560A1/de not_active Ceased
- 2008-03-11 WO PCT/EP2008/052861 patent/WO2008110551A1/en not_active Ceased
- 2008-03-11 JP JP2009553125A patent/JP2010520913A/ja active Pending
- 2008-03-11 AT AT08717608T patent/ATE518544T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP2120980B1 (de) | 2011-08-03 |
| EP2120980A1 (de) | 2009-11-25 |
| ES2371393T3 (es) | 2011-12-30 |
| WO2008110551A1 (en) | 2008-09-18 |
| JP2010520913A (ja) | 2010-06-17 |
| US20110275579A1 (en) | 2011-11-10 |
| CN101765433A (zh) | 2010-06-30 |
| EP2368560A1 (de) | 2011-09-28 |
| US8877717B2 (en) | 2014-11-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |