ATE518948T1 - Verbesserte polymerasen - Google Patents
Verbesserte polymerasenInfo
- Publication number
- ATE518948T1 ATE518948T1 AT06727060T AT06727060T ATE518948T1 AT E518948 T1 ATE518948 T1 AT E518948T1 AT 06727060 T AT06727060 T AT 06727060T AT 06727060 T AT06727060 T AT 06727060T AT E518948 T1 ATE518948 T1 AT E518948T1
- Authority
- AT
- Austria
- Prior art keywords
- dna
- polymerases
- polymerase
- modified
- reaction cycle
- Prior art date
Links
- 238000001712 DNA sequencing Methods 0.000 abstract 1
- 102000016928 DNA-directed DNA polymerase Human genes 0.000 abstract 1
- 108010014303 DNA-directed DNA polymerase Proteins 0.000 abstract 1
- 238000003491 array Methods 0.000 abstract 1
- 239000002773 nucleotide Substances 0.000 abstract 1
- 125000003729 nucleotide group Chemical group 0.000 abstract 1
Landscapes
- Enzymes And Modification Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0509508A GB0509508D0 (en) | 2005-05-10 | 2005-05-10 | Improved polymerases |
| US75799706P | 2006-01-11 | 2006-01-11 | |
| PCT/GB2006/001700 WO2006120433A1 (en) | 2005-05-10 | 2006-05-10 | Improved polymerases |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE518948T1 true ATE518948T1 (de) | 2011-08-15 |
Family
ID=34685371
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT06727060T ATE518948T1 (de) | 2005-05-10 | 2006-05-10 | Verbesserte polymerasen |
Country Status (3)
| Country | Link |
|---|---|
| CN (1) | CN101180390B (de) |
| AT (1) | ATE518948T1 (de) |
| GB (1) | GB0509508D0 (de) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2011220536B2 (en) * | 2010-02-26 | 2012-05-24 | Life Technologies Corporation | Modified proteins and methods of making and using same |
| US11208636B2 (en) | 2011-08-10 | 2021-12-28 | Life Technologies Corporation | Polymerase compositions, methods of making and using same |
| EP2742151B1 (de) * | 2011-08-10 | 2017-10-25 | Life Technologies Corporation | Polymerasezusammensetzungen |
| US9758773B2 (en) * | 2014-02-14 | 2017-09-12 | Agilent Technologies, Inc. | Thermostable type-A DNA polymerase mutant with increased resistance to inhibitors in blood |
| WO2015200693A1 (en) * | 2014-06-27 | 2015-12-30 | Illumina, Inc. | Modified polymerases for improved incorporation of nucleotide analogues |
| US9677057B2 (en) * | 2014-09-30 | 2017-06-13 | Illumina, Inc. | Modified polymerases for improved incorporation of nucleotide analogues |
| US10308918B2 (en) | 2015-02-02 | 2019-06-04 | Roche Molecular Systems, Inc. | Polymerase variants |
| US10526588B2 (en) | 2015-05-14 | 2020-01-07 | Roche Sequencing Solutions, Inc. | Polymerase variants and uses thereof |
| EP3347461A1 (de) * | 2015-09-09 | 2018-07-18 | Qiagen GmbH | Polymeraseenzym |
| US10883092B2 (en) * | 2017-04-18 | 2021-01-05 | Mgi Tech Co., Ltd. | Phi29 DNA polymerase and encoding gene and application thereof |
| CN108795900B (zh) * | 2017-04-27 | 2021-02-02 | 深圳华大智造科技股份有限公司 | Dna聚合酶及其制备方法 |
| ES2969883T3 (es) | 2018-03-21 | 2024-05-23 | Hoffmann La Roche | ADN polimerasas para la incorporación eficiente y eficaz de dNTP metilados |
| CN109022387B (zh) * | 2018-08-29 | 2020-12-22 | 华南理工大学 | 一种突变型Pfu DNA聚合酶及其制备方法和应用 |
| EP3891275A2 (de) * | 2018-12-05 | 2021-10-13 | Illumina, Inc. | Polymerasen, zusammensetzungen und verfahren zur verwendung |
| CN114402067A (zh) * | 2019-09-18 | 2022-04-26 | 美国赛库莱特生物有限公司 | 聚合酶 |
| US12077789B2 (en) * | 2021-08-14 | 2024-09-03 | Illumina, Inc. | Polymerases, compositions, and methods of use |
| CN116286720B (zh) * | 2023-03-29 | 2026-07-17 | 赛纳生物科技(北京)有限公司 | 一种dna聚合酶 |
| WO2025260373A1 (zh) * | 2024-06-21 | 2025-12-26 | 华大工程生物学长荡湖研究所 | 重组型b7 dna聚合酶 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7057026B2 (en) * | 2001-12-04 | 2006-06-06 | Solexa Limited | Labelled nucleotides |
| EP3147292B1 (de) * | 2002-08-23 | 2018-09-26 | Illumina Cambridge Limited | Markierte nukleotide |
| GB0321306D0 (en) * | 2003-09-11 | 2003-10-15 | Solexa Ltd | Modified polymerases for improved incorporation of nucleotide analogues |
-
2005
- 2005-05-10 GB GB0509508A patent/GB0509508D0/en not_active Ceased
-
2006
- 2006-05-10 CN CN200680016045.1A patent/CN101180390B/zh not_active Expired - Fee Related
- 2006-05-10 AT AT06727060T patent/ATE518948T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| CN101180390B (zh) | 2013-04-03 |
| GB0509508D0 (en) | 2005-06-15 |
| CN101180390A (zh) | 2008-05-14 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES2511029T3 (es) | Ensayos de ganancia y pérdida genómica multiplexados | |
| WO2007041342A3 (en) | Labeled nucleotide analogs and uses therefor | |
| ATE542922T1 (de) | 2'-terminator-assoziierte pyrophosphorolyse- aktivierte polymerisierung | |
| SG11201809961TA (en) | Variants of a dna polymerase of the polx family | |
| ATE516371T1 (de) | Oligonukleotide und deren verwendungen | |
| ATE550441T1 (de) | Verfahren, zusammensetzungen und kits zur isothermischen amplifikation von nukleinsäuren | |
| WO2005054508A3 (en) | Gene expression profiling of colon cancer by dna microarrays and correlation with survival and histoclinical parameters | |
| RU2019138698A (ru) | Способы и композиции для днк-профилирования | |
| WO2011056866A3 (en) | Methods and kits for 3'-end-tagging of rna | |
| WO2010141390A3 (en) | Nucleotide transient binding for sequencing methods | |
| EA201070206A1 (ru) | Специализированная многосайтовая комбинаторная сборка | |
| WO2004092418A3 (en) | Global amplification using a randomly primed composite primer | |
| WO2006137941A3 (en) | Methods and compositions involving mirna and mirna inhibitor molecules | |
| JP2016195614A5 (de) | ||
| DK1948822T3 (da) | Multikomponent-nukleinsyreenzymer og fremgangsmåder til deres anvendelse | |
| WO2008093098A3 (en) | Methods for indexing samples and sequencing multiple nucleotide templates | |
| CY1117574T1 (el) | Αναλυση γονιδιωματικων κλασματων με χρηση των αριθμων πολυμορφισμων | |
| WO2009148560A8 (en) | Methods and compositions for nucleic acid sequencing | |
| ATE420170T1 (de) | Matrizengerichtete split-and-mix-synthese von bibliotheken kleiner moleküle | |
| WO2007146819A3 (en) | Methods for identifying and using snp panels | |
| WO2014182528A3 (en) | Multiplex labeling of molecules by sequential hybridization barcoding | |
| MY162156A (en) | Processes using dual specificity oligonucleotide and dual specificity oligonucleotide | |
| IL278771A (en) | Polynucleotides, reagents and methods for nucleic acid hybridization | |
| JP2014504153A5 (de) | ||
| EA201490534A1 (ru) | Способы мечения днк-кодированных библиотек |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |