ATE518953T1 - Verwendung einer mutagenen dna-polymerase zur herstellung willkürlicher mutationen - Google Patents

Verwendung einer mutagenen dna-polymerase zur herstellung willkürlicher mutationen

Info

Publication number
ATE518953T1
ATE518953T1 AT01993683T AT01993683T ATE518953T1 AT E518953 T1 ATE518953 T1 AT E518953T1 AT 01993683 T AT01993683 T AT 01993683T AT 01993683 T AT01993683 T AT 01993683T AT E518953 T1 ATE518953 T1 AT E518953T1
Authority
AT
Austria
Prior art keywords
dna polymerase
mutagenic dna
produce arbitrary
mutations
random mutagenesis
Prior art date
Application number
AT01993683T
Other languages
English (en)
Inventor
Khalil Bouayadi
Hakim Kharrat
Thierry Louat
Laurence Servant
Christophe Cazaux
Jean Hoffmann
Original Assignee
Millegen Sarl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Millegen Sarl filed Critical Millegen Sarl
Application granted granted Critical
Publication of ATE518953T1 publication Critical patent/ATE518953T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/102—Mutagenizing nucleic acids

Landscapes

  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AT01993683T 2000-11-08 2001-11-07 Verwendung einer mutagenen dna-polymerase zur herstellung willkürlicher mutationen ATE518953T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0014333A FR2816319B1 (fr) 2000-11-08 2000-11-08 Utilisation d'adn polymerase mutagene pour la creation de mutations aleatoires
PCT/FR2001/003450 WO2002038756A1 (fr) 2000-11-08 2001-11-07 Utilisation d'adn polymerase mutagene pour la creation de mutations aleatoires

Publications (1)

Publication Number Publication Date
ATE518953T1 true ATE518953T1 (de) 2011-08-15

Family

ID=8856193

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01993683T ATE518953T1 (de) 2000-11-08 2001-11-07 Verwendung einer mutagenen dna-polymerase zur herstellung willkürlicher mutationen

Country Status (6)

Country Link
US (1) US7670809B2 (de)
EP (1) EP1332210B1 (de)
AT (1) ATE518953T1 (de)
AU (1) AU2002223772A1 (de)
FR (1) FR2816319B1 (de)
WO (1) WO2002038756A1 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1811031A1 (de) 2006-01-18 2007-07-25 Millegen Methode zur Auswahl eines Peptids oder Polypeptids das an ein Zielmolekül bindet
WO2007137616A1 (en) * 2006-05-30 2007-12-06 Millegen Highly diversified antibody libraries
US20100093563A1 (en) * 2008-09-22 2010-04-15 Robert Anthony Williamson Methods and vectors for display of molecules and displayed molecules and collections
WO2010033237A2 (en) * 2008-09-22 2010-03-25 Calmune Corporation Methods for creating diversity in libraries and libraries, display vectors and methods, and displayed molecules
CA2742969A1 (en) 2008-11-07 2010-05-14 Fabrus Llc Anti-dll4 antibodies and uses thereof
EP2233500A1 (de) 2009-03-20 2010-09-29 LFB Biotechnologies Optimierte Fc Varianten
WO2011035205A2 (en) 2009-09-18 2011-03-24 Calmune Corporation Antibodies against candida, collections thereof and methods of use
CA2780221A1 (en) 2009-11-04 2011-05-12 Fabrus Llc Methods for affinity maturation-based antibody optimization
MX349622B (es) 2010-09-08 2017-08-07 Halozyme Inc Metodos para evaluar e identificar o evolucionar proteinas terapeuticas condicionalmente activas.
US20160185847A1 (en) 2012-12-17 2016-06-30 Laboratoire Francais Du Fractionnement Et Des Biotechnologies Use of monoclonal antibodies for the treatment of inflammation and bacterial infections
FR3024453B1 (fr) 2014-08-01 2018-06-29 Lab Francais Du Fractionnement Procede de production de variants ayant un fc presentant une sialylation amelioree
FR3035879B1 (fr) 2015-05-07 2025-02-28 Lab Francais Du Fractionnement Mutants fc a activite fonctionnelle modifiee
FR3038517B1 (fr) 2015-07-06 2020-02-28 Laboratoire Francais Du Fractionnement Et Des Biotechnologies Utilisation de fragments fc modifies en immunotherapie
FR3058159B1 (fr) 2016-10-28 2022-02-25 Lab Francais Du Fractionnement Variants de polypeptide fc presentant une demi-vie augmentee

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6255062B1 (en) * 1994-02-14 2001-07-03 California Institute Of Technology β-type DNA polymerases
US6165718A (en) * 1996-01-10 2000-12-26 Novo Nordisk A/S Novo Alle Method for in vivo production of a mutant library in cells
WO1998023733A2 (en) * 1996-11-27 1998-06-04 University Of Washington Thermostable polymerases having altered fidelity
FR2757178B1 (fr) * 1996-12-13 1999-03-05 Centre Nat Rech Scient Utilisation d'un vecteur exprimant l'adn polymerase beta comme medicament

Also Published As

Publication number Publication date
US7670809B2 (en) 2010-03-02
EP1332210A1 (de) 2003-08-06
US20040110294A1 (en) 2004-06-10
EP1332210B1 (de) 2011-08-03
WO2002038756A1 (fr) 2002-05-16
FR2816319B1 (fr) 2004-09-03
AU2002223772A1 (en) 2002-05-21
FR2816319A1 (fr) 2002-05-10

Similar Documents

Publication Publication Date Title
ATE518953T1 (de) Verwendung einer mutagenen dna-polymerase zur herstellung willkürlicher mutationen
DE60027040D1 (de) Zusammensetzungen und methoden zur verwendung von dna polymerasen
CY1110995T1 (el) Ασφαλη μεταλλακτικα ιικα εμβολια
ATE265173T1 (de) Werkzeug zur bearbeitung von nahrungsmitteln und methode zum kennzeichnen dieses werkzeuges
ATE307831T1 (de) Copolymerisierung von vinylchlorid in gegenwart eines stabilen nitroxylradikals
Agarwal et al. Oscillation of certain functional differential equations
ATE279117T1 (de) Kremiges nahrungsmittel auf basis von hartkäse
ATE40405T1 (de) Dns und ihre verwendung.
ATE295390T1 (de) Verwendung alkoxilierter polyvinylamine zur modifizierung von oberflächen
Kalemba-Drożdż Comment on article" Are wild and cultivated flowers served in restaurants or sold by local producers in Denmark safe for the consumer?" Food and Chemical Toxicology 120 (2018) 129-142
DE59912771D1 (de) Kombination von genen zur regulierung der blühinduktion bei nutz- und zierpflanzen
BR0107286A (pt) Folha de esmalte decorada, método de produção e uso de dita folha na indústria cer mica
HUP0101808A2 (hu) Eljárás izomertiszta, magas helyettesítési fokú azaciklikus vegyületek sztereokémiailag szabályozott előállítására
JP1777565S (ja) 包丁
Easterla A Unique Gray Quartziferous Effigy Face Pipe (Historic?) from Northwest Missouri.
Evin et al. Influence of material properties on technological characteristics of deep drawing.
Klaasmeyer Arts and Crafts
Clark Witness appeal: merger victims
Etchegaray Understanding reactions to supervisor monitoring: the importance of attributions and perceptions of justice
Colon et al. Formaldehyde emmissions: Separating myth from reality.
HF A handlebody calculus for topology change
Priddy Retaliation or exhaustion? burnout as a factor in performing incivility
Tohidi et al. Modelling and analysis of productivity teamwork based on information technology
Sari et al. Mathematical Aspects of Kasongan Pottery Art
Kaiser The individual and modern culture as presented in the language of James Joyce and the works of Robert Motherwell.

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 1332210

Country of ref document: EP