ATE518955T1 - Abgeschwächte gram-negative bakterien - Google Patents

Abgeschwächte gram-negative bakterien

Info

Publication number
ATE518955T1
ATE518955T1 AT03719577T AT03719577T ATE518955T1 AT E518955 T1 ATE518955 T1 AT E518955T1 AT 03719577 T AT03719577 T AT 03719577T AT 03719577 T AT03719577 T AT 03719577T AT E518955 T1 ATE518955 T1 AT E518955T1
Authority
AT
Austria
Prior art keywords
gram
weakened
bacterium
negative bacteria
mutant
Prior art date
Application number
AT03719577T
Other languages
English (en)
Inventor
Helen Rachel Crooke
Jacqueline Elizabeth Shea
Robert Graham Feldman
Sylvain Gabriel Coutebroze
Francois-Xavier Legros
Original Assignee
Merial Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merial Llc filed Critical Merial Llc
Application granted granted Critical
Publication of ATE518955T1 publication Critical patent/ATE518955T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/285—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Pasteurellaceae (F), e.g. Haemophilus influenza
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Virology (AREA)
  • General Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT03719577T 2002-04-05 2003-04-04 Abgeschwächte gram-negative bakterien ATE518955T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US37028202P 2002-04-05 2002-04-05
US10/406,686 US7449178B2 (en) 2002-04-05 2003-04-03 Attenuated gram negative bacteria
PCT/US2003/010308 WO2003086277A2 (en) 2002-04-05 2003-04-04 Attenuated gram negative bacteria

Publications (1)

Publication Number Publication Date
ATE518955T1 true ATE518955T1 (de) 2011-08-15

Family

ID=29254405

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03719577T ATE518955T1 (de) 2002-04-05 2003-04-04 Abgeschwächte gram-negative bakterien

Country Status (15)

Country Link
US (3) US7449178B2 (de)
EP (1) EP1575483B1 (de)
JP (1) JP4338528B2 (de)
KR (1) KR101037566B1 (de)
CN (2) CN1934240A (de)
AT (1) ATE518955T1 (de)
AU (2) AU2003223447C1 (de)
BR (1) BRPI0309001B1 (de)
CA (1) CA2481186C (de)
CO (1) CO5640065A1 (de)
ES (1) ES2371498T3 (de)
MX (1) MXPA04009730A (de)
NZ (1) NZ535993A (de)
PT (1) PT1575483E (de)
WO (1) WO2003086277A2 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100551104B1 (ko) * 1994-12-09 2006-02-09 임페리얼 컬리지 이노베이션스 리미티드 유전자의 동정
PT1108034E (pt) * 1998-09-04 2008-11-14 Emergent Product Dev Uk Ltd Mutantes de spi2 de salmonela atenuados como transportadores de antigénios
GB9910812D0 (en) * 1999-05-10 1999-07-07 Microscience Ltd Vaccine composition
PT1350796E (pt) * 2002-04-05 2009-01-23 Merial Sas Bactérias gram-negativas atenuadas
US7449178B2 (en) * 2002-04-05 2008-11-11 Merial Limited Attenuated gram negative bacteria
NZ543771A (en) 2003-07-02 2008-05-30 Biotechnology Res & Dev Acapsular Pasteurella multocida hyae deletion mutants
JP4981684B2 (ja) * 2004-12-22 2012-07-25 インターベツト・インターナシヨナル・ベー・ベー パストゥレラ・マルトシダワクチン
EP2326344A4 (de) 2008-06-16 2013-08-07 Prokarium Ltd Impfstoffe mit salmonellen-vektor gegen chlamydien und anwendungsverfahren
US8917497B2 (en) * 2012-07-23 2014-12-23 Knaack Llc Jobsite storage cabinet for housing electronic equipment
WO2015066292A1 (en) 2013-11-01 2015-05-07 Merial Limited Attenuated pasteurella multocidavaccines & methods of making & use thereof
CN107075562B (zh) * 2014-09-30 2021-09-24 深圳华大基因科技有限公司 用于肥胖症相关疾病的生物标记物
TW202219269A (zh) * 2020-09-30 2022-05-16 美國農業部 新型多殺性巴斯德氏菌株及具有ｈｙａＣ與ｎａｎＰ缺失之疫苗
TW202214294A (zh) * 2020-09-30 2022-04-16 美商碩騰服務公司 具有ｈｙａＣ及ｎａｎＰ缺失之新穎多殺性巴斯德氏菌株及疫苗
CN116144565B (zh) * 2022-12-21 2025-09-26 四川农业大学 减毒多杀性巴氏杆菌及其构建方法和应用
CN117534732B (zh) * 2023-11-03 2024-10-22 湖南中晟全肽生物科技股份有限公司 一种抑制il-12与其受体结合的多肽及其应用

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994011024A1 (en) * 1992-11-06 1994-05-26 Regents Of The University Of Minnesota Composition protective against p. multocida pasteurellosis infection
US6793927B1 (en) * 1993-12-06 2004-09-21 The United States Of America As Represented By The Secretary Of The Department Of Agriculture Construction of Pasteurella haemolytica vaccines
KR100551104B1 (ko) 1994-12-09 2006-02-09 임페리얼 컬리지 이노베이션스 리미티드 유전자의 동정
US6770275B1 (en) * 1996-05-31 2004-08-03 Akzo Nobel N.V. Live attenuated RTC-producing bacteria of the family
US6086894A (en) * 1996-06-27 2000-07-11 Virginia Tech Intellectual Properties, Inc. Recombinant vaccine for diseases caused by encapsulated organisms
US6783764B1 (en) * 1997-04-10 2004-08-31 Akzo Nobel Nv Actinobacillus pleuropneumoniae subunit vaccine
CH692179A5 (de) 1997-06-25 2002-03-15 Kueschall Design Ag Rollstuhl und Sitzmodul für den Rollstuhl,
US20010018055A1 (en) * 1997-09-25 2001-08-30 Briggs Robert E. Deletion mutants of virulence factors of pasteurellaceae
BR0009663A (pt) * 1999-04-09 2002-04-09 Upjohn Co Composições de vacinas antibacterianas
US6790950B2 (en) * 1999-04-09 2004-09-14 Pharmacia & Upjohn Company Anti-bacterial vaccine compositions
GB9910812D0 (en) * 1999-05-10 1999-07-07 Microscience Ltd Vaccine composition
US6780405B1 (en) * 2000-04-28 2004-08-24 Avant Immunotherapeutics, Inc. Regulated antigen delivery system (RADS)
WO2002018601A2 (en) * 2000-08-25 2002-03-07 Abbott Laboratories Essential bacteria genes and genome scanning in haemophilus influenzae for the identification of 'essential genes'
US20040029129A1 (en) * 2001-10-25 2004-02-12 Liangsu Wang Identification of essential genes in microorganisms
PT1350796E (pt) * 2002-04-05 2009-01-23 Merial Sas Bactérias gram-negativas atenuadas
US7449178B2 (en) * 2002-04-05 2008-11-11 Merial Limited Attenuated gram negative bacteria
CA2520386A1 (en) * 2003-03-27 2004-10-14 Children's Hospital, Inc. Nontypeable haemophilus influenzae virulence factors
UA100370C2 (uk) * 2006-12-11 2012-12-25 Мериал Лимитед Спосіб вакцинації птахів проти salmonella
TWI328458B (en) * 2007-03-09 2010-08-11 Univ Nat Chunghsing Subunit vaccine of pasteurella multocida in veterinary uses

Also Published As

Publication number Publication date
US20040033586A1 (en) 2004-02-19
WO2003086277A9 (en) 2006-02-23
KR20050016334A (ko) 2005-02-21
CN102864090A (zh) 2013-01-09
EP1575483A4 (de) 2007-07-04
HK1078271A1 (en) 2006-03-10
AU2010206113B2 (en) 2012-03-15
CO5640065A1 (es) 2006-05-31
WO2003086277A2 (en) 2003-10-23
CA2481186A1 (en) 2003-10-23
NZ535993A (en) 2010-02-26
CN1934240A (zh) 2007-03-21
WO2003086277A3 (en) 2007-03-01
PT1575483E (pt) 2011-09-08
US20090252766A1 (en) 2009-10-08
CA2481186C (en) 2015-10-06
US7943125B2 (en) 2011-05-17
MXPA04009730A (es) 2006-04-28
AU2003223447A1 (en) 2003-10-27
AU2003223447C1 (en) 2011-01-06
ES2371498T3 (es) 2012-01-03
EP1575483A2 (de) 2005-09-21
US8329163B2 (en) 2012-12-11
EP1575483B1 (de) 2011-08-03
US20120009218A1 (en) 2012-01-12
AU2010206113A1 (en) 2010-08-26
BRPI0309001A2 (pt) 2017-07-04
JP4338528B2 (ja) 2009-10-07
BRPI0309001B1 (pt) 2021-11-30
JP2005535296A (ja) 2005-11-24
AU2003223447B2 (en) 2010-06-03
US7449178B2 (en) 2008-11-11
KR101037566B1 (ko) 2011-05-27

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