ATE520033T1 - Neurotoxische aminosäure oder neurotoxisches derivat davon in zusammenhang mit neurologischen erkrankungen - Google Patents
Neurotoxische aminosäure oder neurotoxisches derivat davon in zusammenhang mit neurologischen erkrankungenInfo
- Publication number
- ATE520033T1 ATE520033T1 AT07018126T AT07018126T ATE520033T1 AT E520033 T1 ATE520033 T1 AT E520033T1 AT 07018126 T AT07018126 T AT 07018126T AT 07018126 T AT07018126 T AT 07018126T AT E520033 T1 ATE520033 T1 AT E520033T1
- Authority
- AT
- Austria
- Prior art keywords
- bmaa
- derivative
- neurotoxic
- amino acid
- environmental sample
- Prior art date
Links
- 231100000189 neurotoxic Toxicity 0.000 title abstract 10
- 230000002887 neurotoxic effect Effects 0.000 title abstract 10
- 150000001413 amino acids Chemical class 0.000 title abstract 6
- 201000010099 disease Diseases 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
- 230000000926 neurological effect Effects 0.000 title 1
- UJVHVMNGOZXSOZ-VKHMYHEASA-N L-BMAA Chemical compound CNC[C@H](N)C(O)=O UJVHVMNGOZXSOZ-VKHMYHEASA-N 0.000 abstract 12
- 230000007613 environmental effect Effects 0.000 abstract 11
- 208000012902 Nervous system disease Diseases 0.000 abstract 5
- 229940024606 amino acid Drugs 0.000 abstract 5
- 239000000463 material Substances 0.000 abstract 3
- 238000012216 screening Methods 0.000 abstract 3
- 238000000034 method Methods 0.000 abstract 2
- 238000003556 assay Methods 0.000 abstract 1
- 230000001228 trophic effect Effects 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
- G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6806—Determination of free amino acids
- G01N33/6812—Assays for specific amino acids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2410/00—Assays, e.g. immunoassays or enzyme assays, involving peptides of less than 20 animo acids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2550/00—Electrophoretic profiling, e.g. for proteome analysis
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/28—Neurological disorders
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Immunology (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Pathology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Analytical Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biophysics (AREA)
- Bioinformatics & Computational Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US49468603P | 2003-08-12 | 2003-08-12 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE520033T1 true ATE520033T1 (de) | 2011-08-15 |
Family
ID=34215892
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03818362T ATE377758T1 (de) | 2003-08-12 | 2003-12-08 | Neurotoxische aminosäure oder neurotoxisches derivat davon im zusammenhang mit neurologischen störungen |
| AT07018126T ATE520033T1 (de) | 2003-08-12 | 2003-12-08 | Neurotoxische aminosäure oder neurotoxisches derivat davon in zusammenhang mit neurologischen erkrankungen |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03818362T ATE377758T1 (de) | 2003-08-12 | 2003-12-08 | Neurotoxische aminosäure oder neurotoxisches derivat davon im zusammenhang mit neurologischen störungen |
Country Status (10)
| Country | Link |
|---|---|
| US (5) | US7256002B2 (de) |
| EP (2) | EP1664793B9 (de) |
| JP (1) | JP4312203B2 (de) |
| CN (1) | CN100595588C (de) |
| AT (2) | ATE377758T1 (de) |
| AU (1) | AU2003296424A1 (de) |
| CA (1) | CA2535663C (de) |
| DE (1) | DE60317379T2 (de) |
| DK (1) | DK1664793T3 (de) |
| WO (1) | WO2005019830A1 (de) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7256002B2 (en) * | 2003-08-12 | 2007-08-14 | The Institute For Ethnomedicine | Screening for neurotoxic amino acid associated with neurological disorders |
| US7932287B2 (en) * | 2004-08-12 | 2011-04-26 | Chemgenes Corporation | Therapeutic compositions and uses |
| JP4709278B2 (ja) | 2005-05-23 | 2011-06-22 | エフ． ヘスス ハラルド | 光変換可能な光学標識を用いる光学顕微鏡法 |
| DE102006030976A1 (de) | 2006-07-03 | 2008-01-17 | Behrens, Meinhard, Dr. | Verfahren zum qualitativen Nachweis von zugesetzten Eiweiß-Stoffen in Lebensmitteln |
| EP2677319B1 (de) | 2008-07-09 | 2015-12-30 | The Institute for Ethnomedicine | Antikörper zum Nachweis von neurotoxischen Aminosäuren, die mit neurologischen Krankheiten assoziiert sind |
| CN102234240B (zh) * | 2011-05-05 | 2014-04-09 | 江苏弘和药物研发有限公司 | L-bmaa盐酸盐的合成方法 |
| EP2782566B1 (de) * | 2011-11-21 | 2021-01-06 | The Institute for Ethnomedicine | L-serin zur verwendung bei der behandlung neurodegenerativer erkrankungen |
| US8394596B1 (en) | 2012-04-13 | 2013-03-12 | Abraxis LLC | Antibodies and assays for beta-N-methylamino-L-alanine |
| ITRM20130253A1 (it) * | 2013-04-29 | 2014-10-30 | Canox4Drug S P A | Metodo per la determinazione del rame libero |
| CN103837620A (zh) * | 2014-03-21 | 2014-06-04 | 上海硕源健标生物医学科技有限公司 | 一种同时检测人体血浆中多种氨基酸含量的方法 |
| CN106053678A (zh) * | 2016-08-16 | 2016-10-26 | 汤臣倍健股份有限公司 | 一种辅助降血糖片深加工产品中4‑羟基异亮氨酸含量的检测方法 |
| CN107157793A (zh) * | 2017-07-05 | 2017-09-15 | 芜湖凌梦电子商务有限公司 | 一种营养洗发香波 |
| CN107334651A (zh) * | 2017-07-05 | 2017-11-10 | 芜湖凌梦电子商务有限公司 | 一种营养去屑洗发香波 |
| CN107157790A (zh) * | 2017-07-05 | 2017-09-15 | 芜湖凌梦电子商务有限公司 | 营养去屑洗发香波 |
| CN109524112A (zh) * | 2018-12-26 | 2019-03-26 | 杭州电子科技大学 | 一种基于部分定向相干法的脑功能网络构建方法 |
| CN116593706A (zh) * | 2021-07-07 | 2023-08-15 | 北京常友生物科技有限公司 | 以β-甲氨基-L-丙氨酸为靶点在制备检测孤独症试剂盒中的应用 |
| CN118556642A (zh) * | 2024-06-05 | 2024-08-30 | 北京常友生物科技有限公司 | 一种利用神经毒素诱导大鼠孤独症模型的制备方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5210076A (en) * | 1988-09-13 | 1993-05-11 | Berliner David L | Methods of treating Parkinson's disease using melanin |
| US5824554A (en) * | 1994-09-09 | 1998-10-20 | Mckay; Florine M. | Detection of allergenic substances in food products |
| US6043283A (en) | 1996-09-20 | 2000-03-28 | Baylor College Of Medicine | Tyramine compounds and their neuronal effects |
| ATE366259T1 (de) * | 1999-03-04 | 2007-07-15 | Praecis Pharm Inc | Beta-amyloid-peptidaggregation regulierende peptide mit d-aminosäuren |
| CN1341610A (zh) * | 2000-09-07 | 2002-03-27 | 上海博德基因开发有限公司 | 一种新的多肽——运动神经障碍相关蛋白62.15和编码这种多肽的多核苷酸 |
| AU2002223317A1 (en) * | 2000-11-03 | 2002-05-15 | The University Of British Columbia | Sterol glucoside toxins |
| US7256002B2 (en) * | 2003-08-12 | 2007-08-14 | The Institute For Ethnomedicine | Screening for neurotoxic amino acid associated with neurological disorders |
-
2003
- 2003-12-08 US US10/731,411 patent/US7256002B2/en not_active Expired - Lifetime
- 2003-12-08 AU AU2003296424A patent/AU2003296424A1/en not_active Abandoned
- 2003-12-08 AT AT03818362T patent/ATE377758T1/de active
- 2003-12-08 CA CA2535663A patent/CA2535663C/en not_active Expired - Lifetime
- 2003-12-08 JP JP2005508290A patent/JP4312203B2/ja not_active Expired - Lifetime
- 2003-12-08 DE DE60317379T patent/DE60317379T2/de not_active Expired - Lifetime
- 2003-12-08 AT AT07018126T patent/ATE520033T1/de not_active IP Right Cessation
- 2003-12-08 DK DK03818362T patent/DK1664793T3/da active
- 2003-12-08 CN CN200380110515A patent/CN100595588C/zh not_active Expired - Lifetime
- 2003-12-08 EP EP03818362A patent/EP1664793B9/de not_active Expired - Lifetime
- 2003-12-08 EP EP07018126A patent/EP1860441B1/de not_active Expired - Lifetime
- 2003-12-08 WO PCT/US2003/039202 patent/WO2005019830A1/en not_active Ceased
-
2007
- 2007-06-08 US US11/760,668 patent/US7670783B2/en not_active Expired - Lifetime
- 2007-08-13 US US11/837,899 patent/US7901895B2/en not_active Expired - Lifetime
-
2011
- 2011-01-27 US US13/015,288 patent/US8541184B2/en not_active Expired - Fee Related
-
2013
- 2013-09-20 US US14/033,150 patent/US10048278B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| US10048278B2 (en) | 2018-08-14 |
| JP4312203B2 (ja) | 2009-08-12 |
| HK1090696A1 (en) | 2006-12-29 |
| EP1860441A3 (de) | 2008-03-05 |
| ATE377758T1 (de) | 2007-11-15 |
| EP1664793B9 (de) | 2008-07-16 |
| WO2005019830A1 (en) | 2005-03-03 |
| US7256002B2 (en) | 2007-08-14 |
| DK1664793T3 (da) | 2008-01-28 |
| AU2003296424A1 (en) | 2005-03-10 |
| EP1860441A2 (de) | 2007-11-28 |
| US20070292893A1 (en) | 2007-12-20 |
| JP2007521464A (ja) | 2007-08-02 |
| CN1860369A (zh) | 2006-11-08 |
| US8541184B2 (en) | 2013-09-24 |
| EP1664793A1 (de) | 2006-06-07 |
| DE60317379D1 (de) | 2007-12-20 |
| US7901895B2 (en) | 2011-03-08 |
| EP1664793B1 (de) | 2007-11-07 |
| EP1860441B1 (de) | 2011-08-10 |
| US20070254315A1 (en) | 2007-11-01 |
| DE60317379T2 (de) | 2008-09-11 |
| US20140080140A1 (en) | 2014-03-20 |
| US7670783B2 (en) | 2010-03-02 |
| CN100595588C (zh) | 2010-03-24 |
| CA2535663C (en) | 2011-02-08 |
| US20050042686A1 (en) | 2005-02-24 |
| CA2535663A1 (en) | 2005-03-03 |
| US20110183424A1 (en) | 2011-07-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |