ATE520401T1 - Kombinationen aus einem beta-2-adrenozeptor- agonist und benzothiazolon - Google Patents

Kombinationen aus einem beta-2-adrenozeptor- agonist und benzothiazolon

Info

Publication number
ATE520401T1
ATE520401T1 AT08702047T AT08702047T ATE520401T1 AT E520401 T1 ATE520401 T1 AT E520401T1 AT 08702047 T AT08702047 T AT 08702047T AT 08702047 T AT08702047 T AT 08702047T AT E520401 T1 ATE520401 T1 AT E520401T1
Authority
AT
Austria
Prior art keywords
benzothiazolone
beta
combinations
adrenoceptor agonist
adrenoceptor
Prior art date
Application number
AT08702047T
Other languages
English (en)
Inventor
Elaine Bridget Cadogan
Stephen Connolly
David Nicholls
Katherine Wiley
Alan Young
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Application granted granted Critical
Publication of ATE520401T1 publication Critical patent/ATE520401T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/428—Thiazoles condensed with carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT08702047T 2007-02-08 2008-02-06 Kombinationen aus einem beta-2-adrenozeptor- agonist und benzothiazolon ATE520401T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0702456.5A GB0702456D0 (en) 2007-02-08 2007-02-08 New combination
PCT/GB2008/000386 WO2008096111A1 (en) 2007-02-08 2008-02-06 Combinations of beta- 2 -adrenoceptor agonistic benzothiazolone

Publications (1)

Publication Number Publication Date
ATE520401T1 true ATE520401T1 (de) 2011-09-15

Family

ID=37898976

Family Applications (1)

Application Number Title Priority Date Filing Date
AT08702047T ATE520401T1 (de) 2007-02-08 2008-02-06 Kombinationen aus einem beta-2-adrenozeptor- agonist und benzothiazolon

Country Status (29)

Country Link
US (2) US20100029732A1 (de)
EP (2) EP2117542B1 (de)
JP (1) JP2010518056A (de)
KR (1) KR20090114391A (de)
CN (1) CN101652137A (de)
AR (1) AR065277A1 (de)
AT (1) ATE520401T1 (de)
AU (1) AU2008212713A1 (de)
BR (1) BRPI0806964A2 (de)
CA (1) CA2675465A1 (de)
CL (1) CL2008000379A1 (de)
CO (1) CO6210723A2 (de)
CY (1) CY1111932T1 (de)
DK (1) DK2117542T3 (de)
EC (1) ECSP099567A (de)
ES (1) ES2368967T3 (de)
GB (1) GB0702456D0 (de)
HR (1) HRP20110695T1 (de)
IL (1) IL199840A0 (de)
MX (1) MX2009007865A (de)
PE (1) PE20081759A1 (de)
PL (1) PL2117542T3 (de)
PT (1) PT2117542E (de)
RS (1) RS51956B (de)
RU (1) RU2009133255A (de)
SI (1) SI2117542T1 (de)
TW (1) TW200843750A (de)
UY (1) UY30906A1 (de)
WO (1) WO2008096111A1 (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW200738658A (en) 2005-08-09 2007-10-16 Astrazeneca Ab Novel compounds
TW200738659A (en) * 2005-08-29 2007-10-16 Astrazeneca Ab Novel compounds
TW200745067A (en) 2006-03-14 2007-12-16 Astrazeneca Ab Novel compounds
TW200825084A (en) 2006-11-14 2008-06-16 Astrazeneca Ab New compounds 521
TW200833670A (en) 2006-12-20 2008-08-16 Astrazeneca Ab Novel compounds 569
GB0702458D0 (en) 2007-02-08 2007-03-21 Astrazeneca Ab Salts 668
EP2315589A4 (de) * 2008-05-13 2013-09-11 Astrazeneca Ab Pharmazeutisches produkt enthaltend einen muscarin-rezeptor-antagonisten und einen beta2-adrenorezeptor-agonisten
US8329729B2 (en) 2008-05-13 2012-12-11 Astrazeneca Ab Quinuclidine derivatives as muscarinic M3 receptor antagonists
JP2011524896A (ja) 2008-06-18 2011-09-08 アストラゼネカ・アクチエボラーグ 呼吸器障害の処置用のベータ２−アドレナリン受容体アゴニストとして作用するベンズオキサジノン誘導体
WO2009154562A1 (en) * 2008-06-20 2009-12-23 Astrazeneca Ab Pharmaceutical composition comprising a 4-hydroxy-2-oxo-2, 3- dihydro-1, 3-benzothiazol-7-yl compound for modulation of beta2-adrenoreceptor activity
TW201036957A (en) 2009-02-20 2010-10-16 Astrazeneca Ab Novel salt 628
US9827212B2 (en) 2009-03-18 2017-11-28 The Trustees Of The University Of Pennsylvania Compositions and methods for treating asthma and other lung diseases
US10265311B2 (en) 2009-07-22 2019-04-23 PureTech Health LLC Methods and compositions for treatment of disorders ameliorated by muscarinic receptor activation
ES2742728T3 (es) 2009-07-22 2020-02-17 PureTech Health LLC Composiciones para el tratamiento de trastornos mejorados por la activación del receptor muscarínico
WO2011061527A1 (en) 2009-11-17 2011-05-26 Astrazeneca Ab Combinations comprising a glucocorticoid receptor modulator for the treatment of respiratory diseases
GB201016912D0 (en) 2010-10-07 2010-11-24 Astrazeneca Ab Novel combination
HRP20260435T1 (hr) 2014-09-09 2026-05-08 Vectura Limited Formulacija koja sadrži glikopirolat, postupak i uređaj
EA032221B1 (ru) * 2015-05-04 2019-04-30 Астразенека Аб Производные пиразола, пригодные в качестве ингибиторов белка, активирующего 5-липоксигеназу (flap)
PT3856182T (pt) 2018-09-28 2026-03-10 Karuna Therapeutics Inc Composições e métodos para o tratamento de perturbações melhoradas pela ativação dos recetores muscarínicos

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE378109B (de) 1972-05-19 1975-08-18 Bofors Ab
ES2165768B1 (es) 1999-07-14 2003-04-01 Almirall Prodesfarma Sa Nuevos derivados de quinuclidina y composiciones farmaceuticas que los contienen.
CO5300399A1 (es) 2000-02-25 2003-07-31 Astrazeneca Ab Heterocicliocs que contienen nitrogeno, proceso para su preparacion y composiciones farmaceuticas que los contienen
AR028948A1 (es) 2000-06-20 2003-05-28 Astrazeneca Ab Compuestos novedosos
SE0100902D0 (sv) 2001-03-15 2001-03-15 Astrazeneca Ab Compounds
SE0104251D0 (sv) 2001-12-14 2001-12-14 Astrazeneca Ab Novel compounds
SE0301569D0 (sv) 2003-05-27 2003-05-27 Astrazeneca Ab Novel compounds
SA04250253B1 (ar) 2003-08-21 2009-11-10 استرازينيكا ايه بي احماض فينوكسي اسيتيك مستبدلة باعتبارها مركبات صيدلانية لعلاج الامراض التنفسية مثل الربو ومرض الانسداد الرئوي المزمن
SE0302486D0 (sv) 2003-09-18 2003-09-18 Astrazeneca Ab Novel compounds
GB0324790D0 (en) 2003-10-24 2003-11-26 Astrazeneca Ab Amide derivatives
GB0402797D0 (en) * 2004-02-09 2004-03-10 Novartis Ag Organic compounds
SE0401762D0 (sv) 2004-07-05 2004-07-05 Astrazeneca Ab Novel compounds
CN101048407A (zh) 2004-09-03 2007-10-03 普莱希科公司 双环杂芳基pde4b抑制剂
WO2006046916A1 (en) 2004-10-29 2006-05-04 Astrazeneca Ab Novel sulphonamide derivatives as glucocorticoid receptor modulators for the treatment of inflammatory diseases
WO2006098353A1 (ja) 2005-03-15 2006-09-21 Kyowa Hakko Kogyo Co., Ltd. 外用剤
TW200738658A (en) * 2005-08-09 2007-10-16 Astrazeneca Ab Novel compounds
MX2009000475A (es) 2006-07-19 2009-07-10 Astrazeneca Ab Nuevos compuestos de espiropiperidina triciclicos, su sintesis y sus usos como moduladores de la actividad de los receptores de quimioquinas.

Also Published As

Publication number Publication date
CL2008000379A1 (es) 2008-10-24
PL2117542T3 (pl) 2011-12-30
CA2675465A1 (en) 2008-08-14
US20080242649A1 (en) 2008-10-02
TW200843750A (en) 2008-11-16
EP2117542A1 (de) 2009-11-18
GB0702456D0 (en) 2007-03-21
PE20081759A1 (es) 2009-01-31
CY1111932T1 (el) 2015-11-04
RS51956B (sr) 2012-02-29
AR065277A1 (es) 2009-05-27
UY30906A1 (es) 2008-09-30
MX2009007865A (es) 2009-07-31
CN101652137A (zh) 2010-02-17
ES2368967T3 (es) 2011-11-24
BRPI0806964A2 (pt) 2014-04-08
EP2117542B1 (de) 2011-08-17
CO6210723A2 (es) 2010-10-20
US20100029732A1 (en) 2010-02-04
JP2010518056A (ja) 2010-05-27
PT2117542E (pt) 2011-10-06
IL199840A0 (en) 2010-04-15
KR20090114391A (ko) 2009-11-03
WO2008096111A1 (en) 2008-08-14
RU2009133255A (ru) 2011-03-20
HRP20110695T1 (hr) 2011-11-30
EP2364704A1 (de) 2011-09-14
DK2117542T3 (da) 2011-10-31
SI2117542T1 (sl) 2011-11-30
ECSP099567A (es) 2009-09-29
AU2008212713A1 (en) 2008-08-14

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